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MX2010014041A - Una forma cristalina de posaconazol. - Google Patents

Una forma cristalina de posaconazol.

Info

Publication number
MX2010014041A
MX2010014041A MX2010014041A MX2010014041A MX2010014041A MX 2010014041 A MX2010014041 A MX 2010014041A MX 2010014041 A MX2010014041 A MX 2010014041A MX 2010014041 A MX2010014041 A MX 2010014041A MX 2010014041 A MX2010014041 A MX 2010014041A
Authority
MX
Mexico
Prior art keywords
posaconazole
crystalline form
treat
same
relates
Prior art date
Application number
MX2010014041A
Other languages
English (en)
Inventor
Griesser Ulrich
Wieser Josef
Pichler Arthur
Hotter Andreas
Langes Christoph
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of MX2010014041A publication Critical patent/MX2010014041A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a la forma cristalina IV de posaconazol y composiciones farmacéuticas comprendiendo la misma. La composición farmacéutica puede ser usada para tratar o prevenir infecciones fungales.
MX2010014041A 2008-07-03 2009-06-25 Una forma cristalina de posaconazol. MX2010014041A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13385208P 2008-07-03 2008-07-03
EP08159600A EP2141159A1 (en) 2008-07-03 2008-07-03 A Crystalline form of posaconazole
PCT/EP2009/057975 WO2010000668A1 (en) 2008-07-03 2009-06-25 A crystalline form of posaconazole

Publications (1)

Publication Number Publication Date
MX2010014041A true MX2010014041A (es) 2011-03-03

Family

ID=39951578

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010014041A MX2010014041A (es) 2008-07-03 2009-06-25 Una forma cristalina de posaconazol.

Country Status (17)

Country Link
US (1) US8435998B2 (es)
EP (2) EP2141159A1 (es)
KR (1) KR101639456B1 (es)
CN (1) CN102066363B (es)
AU (1) AU2009265848B2 (es)
BR (1) BRPI0915714A2 (es)
CA (1) CA2728170C (es)
DK (1) DK2318396T5 (es)
ES (1) ES2397592T3 (es)
HR (1) HRP20130026T2 (es)
IL (1) IL209196A (es)
MX (1) MX2010014041A (es)
PL (1) PL2318396T3 (es)
RS (1) RS52673B (es)
SI (1) SI2318396T1 (es)
WO (1) WO2010000668A1 (es)
ZA (1) ZA201008019B (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2130540A1 (en) 2008-06-02 2009-12-09 Sandoz AG Pharmaceutical compositions containing a crystalline form of posaconazole
EP2141159A1 (en) 2008-07-03 2010-01-06 Sandoz AG A Crystalline form of posaconazole
WO2011003992A1 (en) * 2009-07-09 2011-01-13 Sandoz Ag A crystalline form of posaconazole
RU2580318C2 (ru) 2010-05-19 2016-04-10 Сандоз Аг Получение промежуточных продуктов для синтеза позаконазола
JP5956980B2 (ja) * 2010-05-19 2016-07-27 サンド・アクチエンゲゼルシヤフト キラル化合物の調製の方法
WO2011144653A1 (en) 2010-05-19 2011-11-24 Sandoz Ag Process for the preparation of chiral triazolones
AU2011254658B2 (en) 2010-05-19 2016-02-18 Sandoz Ag Purification of posaconazole and of posaconazole intermediates
US9493428B2 (en) 2011-06-16 2016-11-15 Sandoz Ag Process for the preparation of a chiral compound
US20150164890A1 (en) * 2012-06-14 2015-06-18 Sandoz Ag Pharmaceutical compositions comprising crystalline posaconazole
CN105579448B (zh) * 2013-07-25 2018-12-21 桑多斯股份公司 制备泊沙康唑的晶型iv的改进方法
ITMI20132118A1 (it) * 2013-12-18 2015-06-19 Djada Pharmaceutical Sa Una forma cristallina di posaconazolo
ITMI20132115A1 (it) * 2013-12-18 2015-06-19 Djada Pharmaceutical Sa Una forma cristallina di posaconazolo
ITMI20132117A1 (it) * 2013-12-18 2015-06-19 Djada Pharmaceutical Sa Una forma cristallina di posaconazolo
ITMI20132114A1 (it) * 2013-12-18 2015-06-19 Djada Pharmaceutical Sa Una forma cristallina di posaconazolo
DE102014203040A1 (de) 2014-02-19 2015-08-20 Carl Zeiss Smt Gmbh Beleuchtungssystem einer mikrolithographischen Projektionsbelichtungsanlage und Verfahren zum Betreiben eines solchen
CN104370894A (zh) * 2014-10-21 2015-02-25 江苏恒盛药业有限公司 无定型泊沙康唑的制备工艺
CN105622590B (zh) * 2014-10-30 2019-08-20 上海美悦生物科技发展有限公司 一种泊沙康唑的晶型vi及其制备方法
PL3331501T3 (pl) 2015-08-08 2020-03-31 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Preparat o zwiększonej odporności na warunki przewodu pokarmowego zawierający pozakonazol
EP3925601B1 (en) 2016-02-26 2024-07-17 Alfred E. Tiefenbacher (GmbH & Co. KG) Gastro-resistant formulation containing posaconazole and a polymeric precipitation inhibitor
WO2017032908A1 (en) 2016-07-08 2017-03-02 Synthon B.V. Pharmaceutical composition comprising amorphous posaconazole
WO2018096497A1 (en) * 2016-11-28 2018-05-31 Cellix Bio Private Limited Compositions and methods for the treatment of fungal infections
TR201620462A2 (tr) 2016-12-31 2018-07-23 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi POSAKONAZOL İÇEREN FARMASÖTİK BİLEŞİMLER ve ÜRETİM YÖNTEMİ
CN106883221A (zh) * 2017-04-17 2017-06-23 兰州大学 一种无定形泊沙康唑及其制备方法
CN107625729A (zh) * 2017-09-29 2018-01-26 重庆华邦制药有限公司 泊沙康唑口服混悬液及其制备方法
EP4003354A4 (en) * 2019-07-31 2023-11-15 The Regents Of The University Of Michigan POSACONAZOLE COCRYSTALS, METHODS OF MANUFACTURE AND USE THEREOF
GB201917867D0 (en) 2019-12-06 2020-01-22 Pulmocide Ltd Polymorphs
EP4196096A1 (en) 2020-08-13 2023-06-21 Alfred E. Tiefenbacher (GmbH & Co. KG) Gastro-resistant high-strength formulation containing posaconazole
WO2023012378A1 (en) 2021-11-25 2023-02-09 Alfred E. Tiefenbacher (Gmbh Und Co. Kg) Granules containing posaconazole
EP4091604B1 (en) 2021-11-25 2024-04-03 Alfred E. Tiefenbacher (GmbH & Co. KG) Granules containing posaconazole

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US4533254A (en) 1981-04-17 1985-08-06 Biotechnology Development Corporation Apparatus for forming emulsions
DE3544983A1 (de) 1985-12-19 1987-06-25 Hoechst Ag Antimykotisch wirksamer nagellack
DE69428125T2 (de) * 1993-12-21 2002-05-02 Schering Corp., Kenilworth Fungizide tetrahydrofurane
US5625064A (en) * 1995-04-19 1997-04-29 Schering Corporation Process for the preparation of triazolones
MX9701229A (es) 1995-06-02 1997-05-31 Schering Corp Antifungicos de tetrahidrofurano.
US5834472A (en) 1996-05-24 1998-11-10 Schering Corporation Antifungal composition with enhanced bioavailability
US5972381A (en) 1996-06-28 1999-10-26 Schering Corporation Solid solution of an antifungal agent with enhanced bioavailability
HU225233B1 (en) 1997-10-07 2006-08-28 Schering Corp Crystalline polymorph of antifungal triazole derivative, pharmaceuticals containing the same and its use
US6713481B1 (en) 1997-10-17 2004-03-30 David R. Andrews Crystalline antifungal polymorph
KR100607742B1 (ko) 2001-04-03 2006-08-01 쉐링 코포레이션 안정한 액상 현탁제, 및 이를 함유하는, 생체 이용율이 증진된 항진균성 조성물
US7563748B2 (en) 2003-06-23 2009-07-21 Cognis Ip Management Gmbh Alcohol alkoxylate carriers for pesticide active ingredients
JP2008501034A (ja) 2004-05-28 2008-01-17 シェーリング　コーポレイション ポサコナゾールを含む注射用薬学的懸濁液
RU2346996C2 (ru) 2004-06-29 2009-02-20 ЮРОПИЭН НИКЕЛЬ ПиЭлСи Усовершенствованное выщелачивание основных металлов
AU2006264212B2 (en) 2005-06-29 2010-10-28 Compumedics Limited Sensor assembly with conductive bridge
EP2130540A1 (en) 2008-06-02 2009-12-09 Sandoz AG Pharmaceutical compositions containing a crystalline form of posaconazole
EP2141159A1 (en) 2008-07-03 2010-01-06 Sandoz AG A Crystalline form of posaconazole
WO2011000020A1 (en) 2009-06-12 2011-01-06 Sbc Research Pty Ltd Enhanced method of detection
WO2011003992A1 (en) 2009-07-09 2011-01-13 Sandoz Ag A crystalline form of posaconazole

Also Published As

Publication number Publication date
CN102066363B (zh) 2014-11-05
ES2397592T3 (es) 2013-03-08
AU2009265848A1 (en) 2010-01-07
ES2397592T9 (es) 2013-08-30
US20110065722A1 (en) 2011-03-17
PL2318396T3 (pl) 2013-03-29
BRPI0915714A2 (pt) 2015-10-27
EP2318396B1 (en) 2012-10-24
CA2728170A1 (en) 2010-01-07
DK2318396T5 (da) 2013-09-02
HRP20130026T2 (en) 2013-10-11
AU2009265848B2 (en) 2014-02-20
WO2010000668A1 (en) 2010-01-07
CA2728170C (en) 2017-02-14
SI2318396T1 (sl) 2013-02-28
KR101639456B1 (ko) 2016-07-13
IL209196A0 (en) 2011-01-31
HRP20130026T1 (hr) 2013-02-28
EP2318396A1 (en) 2011-05-11
DK2318396T3 (da) 2013-02-04
KR20110025763A (ko) 2011-03-11
EP2318396B9 (en) 2013-05-29
IL209196A (en) 2015-08-31
CN102066363A (zh) 2011-05-18
ZA201008019B (en) 2012-02-29
US8435998B2 (en) 2013-05-07
EP2141159A1 (en) 2010-01-06
RS52673B (sr) 2013-06-28

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