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WO2009025080A1 - 大腸癌マーカポリペプチド、及び大腸癌の診断方法 - Google Patents

大腸癌マーカポリペプチド、及び大腸癌の診断方法 Download PDF

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Publication number
WO2009025080A1
WO2009025080A1 PCT/JP2008/002217 JP2008002217W WO2009025080A1 WO 2009025080 A1 WO2009025080 A1 WO 2009025080A1 JP 2008002217 W JP2008002217 W JP 2008002217W WO 2009025080 A1 WO2009025080 A1 WO 2009025080A1
Authority
WO
WIPO (PCT)
Prior art keywords
colorectal cancer
marker polypeptide
cancer marker
diagnosis
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/002217
Other languages
English (en)
French (fr)
Inventor
Yoshio Kodera
Tadakazu Maeda
Yusuke Kawashima
Fumio Nomura
Takeshi Tomonaga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kitasato Institute
Chiba University NUC
Original Assignee
Kitasato Institute
Chiba University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kitasato Institute, Chiba University NUC filed Critical Kitasato Institute
Priority to JP2009528951A priority Critical patent/JP5570810B2/ja
Publication of WO2009025080A1 publication Critical patent/WO2009025080A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • G01N33/57535—

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

　【課題】　体液試料、特に血清等に存在する大腸癌マーカポリペプチド、及び該大腸癌マーカを検出する大腸癌の診断方法を提供する。 　　【解決手段】　配列番号１、２、３、及び５のいずれか１のアミノ酸配列を含む大腸癌マーカポリペプチド；並びに配列番号１、２、３、及び５のいずれか１のアミノ酸配列を含む、大腸癌マーカポリペプチドの少なくとも１種を、被験者から得た体液試料から検出することを特徴とする、大腸癌の診断方法である。 　　
PCT/JP2008/002217 2007-08-18 2008-08-15 大腸癌マーカポリペプチド、及び大腸癌の診断方法 Ceased WO2009025080A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009528951A JP5570810B2 (ja) 2007-08-18 2008-08-15 大腸癌マーカポリペプチド、及び大腸癌の診断方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007213211 2007-08-18
JP2007-213211 2007-08-18

Publications (1)

Publication Number Publication Date
WO2009025080A1 true WO2009025080A1 (ja) 2009-02-26

Family

ID=40377989

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/002217 Ceased WO2009025080A1 (ja) 2007-08-18 2008-08-15 大腸癌マーカポリペプチド、及び大腸癌の診断方法

Country Status (2)

Country Link
JP (1) JP5570810B2 (ja)
WO (1) WO2009025080A1 (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011150517A3 (en) * 2010-06-01 2012-01-26 Miraculins, Inc. Xyxin fragment biomarker for diagnosis of colon cancer
JP2015108515A (ja) * 2013-12-03 2015-06-11 株式会社プロトセラ 大腸癌の診断のための検査方法
JP2016148623A (ja) * 2015-02-13 2016-08-18 京都府公立大学法人 大腸がんの検出方法
WO2024203701A1 (ja) * 2023-03-30 2024-10-03 国立大学法人東海国立大学機構 情報処理装置、情報処理方法、および、コンピュータプログラム
CN121186358A (zh) * 2025-11-25 2025-12-23 长兴固容生物科技有限公司 一种用于肠癌筛查、诊断的标志物组及其用途

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004020583A2 (en) * 2002-08-27 2004-03-11 Bristol-Myers Squibb Company Polynucleotide predictor set for identifying protein tyrosine kinase modulators
WO2004030615A2 (en) * 2002-10-02 2004-04-15 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
WO2004090550A2 (en) * 2003-04-08 2004-10-21 Colotech A/S A method for detection of colorectal cancer in human samples
WO2005054508A2 (en) * 2003-12-01 2005-06-16 Ipsogen Gene expression profiling of colon cancer by dna microarrays and correlation with survival and histoclinical parameters
WO2006053592A1 (en) * 2004-08-13 2006-05-26 Indivumed Gmbh Use of c3a and derivatives thereof as a biomarker for colorectal ademona and/or carcinoma; diagnosis method and test system using the same
WO2006125021A2 (en) * 2005-05-16 2006-11-23 Dana Farber Cancer Institute, Inc. Fibrinogen alpha and hemoglobin polypeptides as cancer markers

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004020583A2 (en) * 2002-08-27 2004-03-11 Bristol-Myers Squibb Company Polynucleotide predictor set for identifying protein tyrosine kinase modulators
WO2004030615A2 (en) * 2002-10-02 2004-04-15 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
WO2004090550A2 (en) * 2003-04-08 2004-10-21 Colotech A/S A method for detection of colorectal cancer in human samples
WO2005054508A2 (en) * 2003-12-01 2005-06-16 Ipsogen Gene expression profiling of colon cancer by dna microarrays and correlation with survival and histoclinical parameters
WO2006053592A1 (en) * 2004-08-13 2006-05-26 Indivumed Gmbh Use of c3a and derivatives thereof as a biomarker for colorectal ademona and/or carcinoma; diagnosis method and test system using the same
WO2006125021A2 (en) * 2005-05-16 2006-11-23 Dana Farber Cancer Institute, Inc. Fibrinogen alpha and hemoglobin polypeptides as cancer markers

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
KODERA YOSHIO ET AL.: "Daichogan no peptide shuyo marker no kaihatsu", THE JAPANESE CANCER ASSOCIATION GAKUJUTSU SOKAI KIJI, vol. 66TH, 25 August 2007 (2007-08-25), pages 88 - 89 *
KOOMEN M.JOHN ET AL.: "Diagnostic protein discovery using liquid chromatography/mass spectrometry for proteolytic peptide targeting", RAPID COMMUNICATIONS IN MASS SPECTROMETRY, vol. 19, 2005, pages 1624 - 1636 *
WARD D.G. ET AL.: "Identification of serum biomarkers for colon by proteomic analysis", BRITISH JOURNAL OF CANCER, vol. 94, 2006, pages 1898 - 1905 *
ZHENG G.X. ET AL.: "Establishment of serum protein pattern for screening colorectal cancer using SELDI-TOF MS", EXP.ONCOL., vol. 28, no. 4, 2006, pages 282 - 287 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011150517A3 (en) * 2010-06-01 2012-01-26 Miraculins, Inc. Xyxin fragment biomarker for diagnosis of colon cancer
EP2576610A4 (en) * 2010-06-01 2014-03-05 Miraculins Inc BIOMARKERS FOR THE DIAGNOSIS AND TREATMENT OF DARM CANCER
JP2015108515A (ja) * 2013-12-03 2015-06-11 株式会社プロトセラ 大腸癌の診断のための検査方法
JP2016148623A (ja) * 2015-02-13 2016-08-18 京都府公立大学法人 大腸がんの検出方法
WO2024203701A1 (ja) * 2023-03-30 2024-10-03 国立大学法人東海国立大学機構 情報処理装置、情報処理方法、および、コンピュータプログラム
CN121186358A (zh) * 2025-11-25 2025-12-23 长兴固容生物科技有限公司 一种用于肠癌筛查、诊断的标志物组及其用途

Also Published As

Publication number Publication date
JPWO2009025080A1 (ja) 2010-11-18
JP5570810B2 (ja) 2014-08-13

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