[go: up one dir, main page]

WO2009004999A8 - シームレスカプセル - Google Patents

シームレスカプセル Download PDF

Info

Publication number
WO2009004999A8
WO2009004999A8 PCT/JP2008/061721 JP2008061721W WO2009004999A8 WO 2009004999 A8 WO2009004999 A8 WO 2009004999A8 JP 2008061721 W JP2008061721 W JP 2008061721W WO 2009004999 A8 WO2009004999 A8 WO 2009004999A8
Authority
WO
WIPO (PCT)
Prior art keywords
seamless capsule
interfacial tension
tension regulator
gelation accelerator
capsule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/061721
Other languages
English (en)
French (fr)
Other versions
WO2009004999A1 (ja
Inventor
Tomohiro Yoshinari
Yoshihiro Uchiyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40226045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2009004999(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to NZ582576A priority Critical patent/NZ582576A/en
Priority to JP2009521608A priority patent/JP5047285B2/ja
Priority to ES08790686T priority patent/ES2748934T3/es
Priority to AU2008272135A priority patent/AU2008272135B2/en
Priority to CN2008801051658A priority patent/CN101801416B/zh
Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Priority to US12/452,374 priority patent/US20100119598A1/en
Priority to EP08790686.3A priority patent/EP2172225B1/en
Publication of WO2009004999A1 publication Critical patent/WO2009004999A1/ja
Publication of WO2009004999A8 publication Critical patent/WO2009004999A8/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

　本発明は、界面張力調整剤やゲル化促進剤を使用しないシームレスカプセルの提供を目的とする。本発明において、ゼラチンおよび可塑剤を含有し、かつ、界面張力調整剤またはゲル化促進剤を含有しないシェル組成物により形成されたシェル、および、界面張力調整剤またはゲル化促進剤を含有しないカプセル内容物からなるシームレスカプセルを提供する。
PCT/JP2008/061721 2007-06-29 2008-06-27 シームレスカプセル Ceased WO2009004999A1 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
EP08790686.3A EP2172225B1 (en) 2007-06-29 2008-06-27 Seamless capsule
JP2009521608A JP5047285B2 (ja) 2007-06-29 2008-06-27 シームレスカプセル
ES08790686T ES2748934T3 (es) 2007-06-29 2008-06-27 Cápsula sin costura
AU2008272135A AU2008272135B2 (en) 2007-06-29 2008-06-27 Seamless capsule
CN2008801051658A CN101801416B (zh) 2007-06-29 2008-06-27 无缝胶囊
NZ582576A NZ582576A (en) 2007-06-29 2008-06-27 Seamless capsule comprising gelatin and a plasticizer
US12/452,374 US20100119598A1 (en) 2007-06-29 2008-06-27 Seamless capsule

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-173198 2007-06-29
JP2007173198 2007-06-29

Publications (2)

Publication Number Publication Date
WO2009004999A1 WO2009004999A1 (ja) 2009-01-08
WO2009004999A8 true WO2009004999A8 (ja) 2009-04-09

Family

ID=40226045

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/061721 Ceased WO2009004999A1 (ja) 2007-06-29 2008-06-27 シームレスカプセル

Country Status (11)

Country Link
US (1) US20100119598A1 (ja)
EP (1) EP2172225B1 (ja)
JP (1) JP5047285B2 (ja)
KR (1) KR20100039362A (ja)
CN (2) CN102552213A (ja)
AU (1) AU2008272135B2 (ja)
ES (1) ES2748934T3 (ja)
MY (1) MY157882A (ja)
NZ (1) NZ582576A (ja)
TW (1) TW200911358A (ja)
WO (1) WO2009004999A1 (ja)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA100403C2 (en) * 2008-01-10 2012-12-25 Такеда Фармасьютикал Компани Лимитед Capsule formulation
ES2632967T3 (es) 2008-09-02 2017-09-18 Amarin Pharmaceuticals Ireland Limited Composición farmacéutica que comprende ácido eicosapentaenoico y ácido nicotínico y métodos de uso de la misma
EP3616694A1 (en) 2009-02-10 2020-03-04 Amarin Pharmaceuticals Ireland Limited Eicosapentaenoic acid ethyl ester for treating hypertriglyceridemia
AU2010241571B2 (en) 2009-04-29 2014-06-26 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
EP4008327A1 (en) 2009-04-29 2022-06-08 Amarin Pharmaceuticals Ireland Limited Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
LT2443246T (lt) * 2009-06-15 2018-03-26 Amarin Pharmaceuticals Ireland Limited Kompozicijos ir būdai, skirti trigliceridų sumažinimui, nepakeliant ldl-c lygio subjekte, kartu taikant statino terapiją
JP5421674B2 (ja) * 2009-07-01 2014-02-19 株式会社ファンケル ソフトカプセル用乳化組成物及びソフトカプセル剤
MX2012003555A (es) 2009-09-23 2012-07-03 Amarin Corp Plc Composicion farmaceutica que comprende acido graso omega-3 y derivado hidroxi de una estatina y metodos para usar la misma.
US11712429B2 (en) 2010-11-29 2023-08-01 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
WO2012074930A2 (en) 2010-11-29 2012-06-07 Amarin Pharma, Inc. Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
JP5876695B2 (ja) * 2011-09-29 2016-03-02 森下仁丹株式会社 シームレスカプセルおよびその製造方法
WO2013070735A1 (en) 2011-11-07 2013-05-16 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
US11291643B2 (en) 2011-11-07 2022-04-05 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
JP6307442B2 (ja) 2012-01-06 2018-04-04 アマリン ファーマシューティカルス アイルランド リミテッド 対象の高感度（ｈｓ−ｃｒｐ）のレベルを低下させる組成物および方法
EA039108B1 (ru) 2012-06-29 2021-12-06 Амарин Фармасьютикалз Айрлэнд Лимитед Способы уменьшения риска развития сердечно-сосудистого события у субъекта, получающего терапию статином
WO2014074552A2 (en) 2012-11-06 2014-05-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy
US9814733B2 (en) 2012-12-31 2017-11-14 A,arin Pharmaceuticals Ireland Limited Compositions comprising EPA and obeticholic acid and methods of use thereof
US20140187633A1 (en) 2012-12-31 2014-07-03 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
US9452151B2 (en) 2013-02-06 2016-09-27 Amarin Pharmaceuticals Ireland Limited Methods of reducing apolipoprotein C-III
US9624492B2 (en) 2013-02-13 2017-04-18 Amarin Pharmaceuticals Ireland Limited Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
US9662307B2 (en) 2013-02-19 2017-05-30 The Regents Of The University Of Colorado Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof
US9283201B2 (en) 2013-03-14 2016-03-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for treating or preventing obesity in a subject in need thereof
US20140271841A1 (en) 2013-03-15 2014-09-18 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin
WO2014170947A1 (ja) 2013-04-15 2014-10-23 三生医薬株式会社 崩壊可能なカプセル及びその製造方法並びに喫煙器具
US10966968B2 (en) 2013-06-06 2021-04-06 Amarin Pharmaceuticals Ireland Limited Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
US20150065572A1 (en) 2013-09-04 2015-03-05 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing prostate cancer
US9585859B2 (en) 2013-10-10 2017-03-07 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
RU2670930C9 (ru) * 2014-01-31 2018-12-13 Морисита Дзинтан Ко., Лтд. Препарат для перорального введения жвачным животным и содержащий его корм для жвачных животных
US10561631B2 (en) 2014-06-11 2020-02-18 Amarin Pharmaceuticals Ireland Limited Methods of reducing RLP-C
WO2015195662A1 (en) 2014-06-16 2015-12-23 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense ldl or membrane polyunsaturated fatty acids
US10406130B2 (en) 2016-03-15 2019-09-10 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
JP6884369B2 (ja) * 2016-12-28 2021-06-09 三生医薬株式会社 シームレスカプセル
TW201900160A (zh) 2017-05-19 2019-01-01 愛爾蘭商艾瑪琳製藥愛爾蘭有限公司 用於降低腎功能下降之個體中的三酸甘油酯之組合物及方法
US11058661B2 (en) 2018-03-02 2021-07-13 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L
SI4056176T1 (sl) 2018-09-24 2024-09-30 Amarin Pharmaceuticals Ireland Limited Metode zmanjševanja tveganja za kardiovaskularne dogodke pri subjektu
CN111040021B (zh) * 2018-10-12 2023-06-02 浙江道尔生物科技有限公司 一种改善生物活性蛋白性质的载体蛋白
JP6603817B1 (ja) 2019-01-18 2019-11-06 三生医薬株式会社 シ−ムレスカプセルならびにこれを含むフィルターおよび喫煙器具
KR20200105068A (ko) 2019-02-28 2020-09-07 우석대학교 산학협력단 오일을 함유하는 심리스 캡슐의 제조방법
BR112022009189A2 (pt) 2019-11-12 2022-07-26 Amarin Pharmaceuticals Ie Ltd Métodos para reduzir o risco de eventos cardiovasculares em um sujeito com fibrilação atrial e/ou palpitação atrial
KR102204696B1 (ko) * 2019-12-10 2021-01-19 한국 한의학 연구원 1-모노에이코사펜타에노인을 유효성분으로 함유하는 주름개선용 조성물
CN115361940A (zh) 2020-03-30 2022-11-18 三生医药株式会社 含有薄荷醇的组合物
KR20230111206A (ko) 2020-11-06 2023-07-25 갓코 호진 긴키 다이가쿠 혈관 질환 치료용 조성물, 혈관 질환 예방용 조성물, 고혈압 치료용 조성물 및 고혈압 예방용 조성물
JP6913976B1 (ja) * 2020-11-13 2021-08-04 東洋カプセル株式会社 シームレスカプセル及びその製造方法
AU2022263358A1 (en) 2021-04-21 2023-11-30 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of heart failure
CN117813080A (zh) 2021-09-14 2024-04-02 三生医药株式会社 含石竹烯组合物
MX2024002865A (es) 2021-09-14 2024-03-21 Sunsho Pharmaceutical Co Ltd Composicion que contiene cariofileno.
KR102864596B1 (ko) 2022-04-25 2025-09-26 유엠에스엔지니어링 주식회사 오메가 3 심리스 연질캡슐 제조방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8819110D0 (en) * 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production
JP2806564B2 (ja) * 1989-07-20 1998-09-30 森下仁丹株式会社 親水性物質を内容物とするシームレスカプセルおよびその製法
JPH0412083A (ja) * 1990-04-27 1992-01-16 Osaka Titanium Co Ltd シリコン単結晶製造方法
JP3159724B2 (ja) 1991-04-19 2001-04-23 フロイント産業株式会社 シームレスカプセル製造方法および装置
JPH0826976A (ja) * 1994-07-21 1996-01-30 Freunt Ind Co Ltd 食品状医薬品
US5650232A (en) 1994-10-07 1997-07-22 Warner-Lambert Company Method for making seamless capsules
JP3759986B2 (ja) * 1995-12-07 2006-03-29 フロイント産業株式会社 シームレスカプセルおよびその製造方法
DK1157692T3 (da) * 2000-05-22 2006-02-06 Pro Aparts Investimentos E Con Sammensætning af fedtsyrer indeholdende mindst 80 vægt-% EPA og DHA, derivater deraf og farmaceutisk anvendelse deraf
ES2272632T3 (es) * 2002-12-05 2007-05-01 SYMRISE GMBH & CO. KG Capsulas rellenas cin costura.
AU2003288606A1 (en) * 2002-12-20 2004-07-14 Pronova Biocare As Use of a fatty acid composition for treatment of male infertility
JP2004262774A (ja) * 2003-02-20 2004-09-24 Freunt Ind Co Ltd シームレスカプセル
GB0403247D0 (en) * 2004-02-13 2004-03-17 Tillotts Pharma Ag A pharmaceutical composition
CA2557113A1 (en) * 2004-02-17 2005-08-25 Symrise Gmbh & Co. Kg Coated spherical seamless filled capsules
US20090304784A1 (en) * 2006-07-28 2009-12-10 V. Mane Fils Seamless capsules containing high amounts of polyunsaturated fatty acids and a flavouring component

Also Published As

Publication number Publication date
CN101801416B (zh) 2012-10-24
AU2008272135B2 (en) 2013-10-31
AU2008272135A1 (en) 2009-01-08
JPWO2009004999A1 (ja) 2010-08-26
ES2748934T3 (es) 2020-03-18
CN101801416A (zh) 2010-08-11
US20100119598A1 (en) 2010-05-13
EP2172225B1 (en) 2019-08-07
EP2172225A8 (en) 2011-06-29
TW200911358A (en) 2009-03-16
WO2009004999A1 (ja) 2009-01-08
KR20100039362A (ko) 2010-04-15
CN102552213A (zh) 2012-07-11
NZ582576A (en) 2012-05-25
MY157882A (en) 2016-07-29
EP2172225A4 (en) 2011-04-27
JP5047285B2 (ja) 2012-10-10
EP2172225A1 (en) 2010-04-07

Similar Documents

Publication Publication Date Title
WO2009004999A1 (ja) シームレスカプセル
WO2009114601A3 (en) Preparation of lenalidomide
WO2007143104A8 (en) Antibodies as t cell receptor mimics, methods of production and uses thereof
WO2007081793A3 (en) Room temperature curable organopolysiloxane composition
WO2008064353A3 (en) 7,8-saturated-4,5-epoxy-morphinanium analogs
WO2007143651A3 (en) Chewable co-enzyme q-10 capsule
TW200736158A (en) Chlorine dioxide generating composition
MXPA05011026A (es) Pelicula de gel termo-reversible homogenea que contiene carragenano kappa-2 y capsulas blandas hechas a partir de la misma.
MY160203A (en) Liposome composition
BRPI0707334B8 (pt) formulação de cápsula de gelatina mole de um composto 15-ceto-prostaglandina e método para estabilização do um composto 15-cetoprostaglandina
WO2009126960A3 (en) Multilayer fragrance encapsulation
EP2942599A3 (en) Composition suitable for a deflagration to detonation transition device
WO2010122332A3 (en) Xanthan gum and swellable particulate containing composition and uses thereof
EP1976993A4 (en) THERMACETOGENIUM PHAEUM CONSORTIUM FOR THE MANUFACTURE OF MATERIALS WITH INCREASED HYDROGEN CONTENT
WO2010043408A3 (de) Mikroverkapseltes fesoterodin
WO2009143841A8 (en) Film-coated compressed chewing gum
WO2008071800A3 (en) Filled plastic material composition
WO2012075015A3 (en) Oral metronidazole pharmaceutical compositions
WO2011051967A3 (en) Pharmaceutical compositions comprising mycophenolate and processes for preparing thereof
WO2008099835A1 (ja) Ｐｅｇ充填硬質カプセル剤のバンドシール
WO2009075329A1 (ja) 分解性を調整したゼラチン組成物
BR112013002717A2 (pt) acesso baseado em rede a conteúdo de vídeo associado com correio de voz
WO2008008548A3 (en) Engine with hybrid crankcase
WO2007132359A3 (en) Composition containing lactobacillus sp. and a cannabinoid receptor and/or a opioid receptor agonist
WO2010128526A3 (en) Oxygen scavenging polyester composition

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200880105165.8

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08790686

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2009521608

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 12009502459

Country of ref document: PH

WWE Wipo information: entry into national phase

Ref document number: 8341/DELNP/2009

Country of ref document: IN

Ref document number: 2008790686

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 12452374

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2008272135

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 582576

Country of ref document: NZ

ENP Entry into the national phase

Ref document number: 20107001925

Country of ref document: KR

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: 2008272135

Country of ref document: AU

Date of ref document: 20080627

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: PI 20095565

Country of ref document: MY