[go: up one dir, main page]

WO2009004999A8 - シームレスカプセル - Google Patents

シームレスカプセル Download PDF

Info

Publication number
WO2009004999A8
WO2009004999A8 PCT/JP2008/061721 JP2008061721W WO2009004999A8 WO 2009004999 A8 WO2009004999 A8 WO 2009004999A8 JP 2008061721 W JP2008061721 W JP 2008061721W WO 2009004999 A8 WO2009004999 A8 WO 2009004999A8
Authority
WO
WIPO (PCT)
Prior art keywords
seamless capsule
interfacial tension
tension regulator
gelation accelerator
capsule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/061721
Other languages
English (en)
French (fr)
Other versions
WO2009004999A1 (ja
Inventor
Tomohiro Yoshinari
Yoshihiro Uchiyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40226045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2009004999(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to JP2009521608A priority Critical patent/JP5047285B2/ja
Priority to NZ582576A priority patent/NZ582576A/en
Priority to US12/452,374 priority patent/US20100119598A1/en
Priority to AU2008272135A priority patent/AU2008272135B2/en
Priority to EP08790686.3A priority patent/EP2172225B1/en
Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Priority to ES08790686T priority patent/ES2748934T3/es
Priority to CN2008801051658A priority patent/CN101801416B/zh
Publication of WO2009004999A1 publication Critical patent/WO2009004999A1/ja
Publication of WO2009004999A8 publication Critical patent/WO2009004999A8/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

　本発明は、界面張力調整剤やゲル化促進剤を使用しないシームレスカプセルの提供を目的とする。本発明において、ゼラチンおよび可塑剤を含有し、かつ、界面張力調整剤またはゲル化促進剤を含有しないシェル組成物により形成されたシェル、および、界面張力調整剤またはゲル化促進剤を含有しないカプセル内容物からなるシームレスカプセルを提供する。
PCT/JP2008/061721 2007-06-29 2008-06-27 シームレスカプセル Ceased WO2009004999A1 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CN2008801051658A CN101801416B (zh) 2007-06-29 2008-06-27 无缝胶囊
NZ582576A NZ582576A (en) 2007-06-29 2008-06-27 Seamless capsule comprising gelatin and a plasticizer
US12/452,374 US20100119598A1 (en) 2007-06-29 2008-06-27 Seamless capsule
AU2008272135A AU2008272135B2 (en) 2007-06-29 2008-06-27 Seamless capsule
EP08790686.3A EP2172225B1 (en) 2007-06-29 2008-06-27 Seamless capsule
JP2009521608A JP5047285B2 (ja) 2007-06-29 2008-06-27 シームレスカプセル
ES08790686T ES2748934T3 (es) 2007-06-29 2008-06-27 Cápsula sin costura

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-173198 2007-06-29
JP2007173198 2007-06-29

Publications (2)

Publication Number Publication Date
WO2009004999A1 WO2009004999A1 (ja) 2009-01-08
WO2009004999A8 true WO2009004999A8 (ja) 2009-04-09

Family

ID=40226045

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/061721 Ceased WO2009004999A1 (ja) 2007-06-29 2008-06-27 シームレスカプセル

Country Status (11)

Country Link
US (1) US20100119598A1 (ja)
EP (1) EP2172225B1 (ja)
JP (1) JP5047285B2 (ja)
KR (1) KR20100039362A (ja)
CN (2) CN102552213A (ja)
AU (1) AU2008272135B2 (ja)
ES (1) ES2748934T3 (ja)
MY (1) MY157882A (ja)
NZ (1) NZ582576A (ja)
TW (1) TW200911358A (ja)
WO (1) WO2009004999A1 (ja)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2711814A1 (en) * 2008-01-10 2009-07-16 Takeda Pharmaceutical Company Limited Capsule formulation
EP4137128A1 (en) 2008-09-02 2023-02-22 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and a statin, and methods of using same
NZ594395A (en) 2009-02-10 2014-01-31 Amarin Pharmaceuticals Ie Ltd Use of eicosapentaenoic acid ethyl ester for treating hypertriglyceridemia
US20120100208A1 (en) 2009-04-29 2012-04-26 Amarin Pharma, Inc. Stable pharmaceutical composition and methods of using same
US20120093922A1 (en) 2009-04-29 2012-04-19 Amarin Corporation Plc Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
SG177254A1 (en) 2009-06-15 2012-02-28 Ian Osterloh Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy
JP5421674B2 (ja) * 2009-07-01 2014-02-19 株式会社ファンケル ソフトカプセル用乳化組成物及びソフトカプセル剤
US20110071176A1 (en) 2009-09-23 2011-03-24 Amarin Pharma, Inc. Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same
WO2012074930A2 (en) 2010-11-29 2012-06-07 Amarin Pharma, Inc. Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
US11712429B2 (en) 2010-11-29 2023-08-01 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
JP5876695B2 (ja) 2011-09-29 2016-03-02 森下仁丹株式会社 シームレスカプセルおよびその製造方法
US11291643B2 (en) 2011-11-07 2022-04-05 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
EP2775837A4 (en) 2011-11-07 2015-10-28 Amarin Pharmaceuticals Ie Ltd METHODS OF TREATING HYPERTRIGLYCERIDEMIA
ES2891473T3 (es) 2012-01-06 2022-01-28 Amarin Pharmaceuticals Ie Ltd Composiciones y métodos para reducir los niveles de alta sensibilidad (hs-CRP) en un sujeto
PT4342546T (pt) 2012-06-29 2025-09-01 Amarin Pharmaceuticals Ie Ltd Éster etílico do ácido eicosapentanoico para utilização na redução do risco de acidente vascular cerebral não-fatal num indivíduo em terapia com estatina
WO2014074552A2 (en) 2012-11-06 2014-05-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy
US9814733B2 (en) 2012-12-31 2017-11-14 A,arin Pharmaceuticals Ireland Limited Compositions comprising EPA and obeticholic acid and methods of use thereof
US20140187633A1 (en) 2012-12-31 2014-07-03 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
US9452151B2 (en) 2013-02-06 2016-09-27 Amarin Pharmaceuticals Ireland Limited Methods of reducing apolipoprotein C-III
US9624492B2 (en) 2013-02-13 2017-04-18 Amarin Pharmaceuticals Ireland Limited Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
US9662307B2 (en) 2013-02-19 2017-05-30 The Regents Of The University Of Colorado Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof
US9283201B2 (en) 2013-03-14 2016-03-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for treating or preventing obesity in a subject in need thereof
US20140271841A1 (en) 2013-03-15 2014-09-18 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin
AP2015008369A0 (en) 2013-04-15 2015-04-30 Sunsho Pharmaceutical Co Ltd Disintegrable capsule, manufacturing method for same, and smoking device containing said disintegrable capsule
US10966968B2 (en) 2013-06-06 2021-04-06 Amarin Pharmaceuticals Ireland Limited Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
US20150065572A1 (en) 2013-09-04 2015-03-05 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing prostate cancer
US9585859B2 (en) 2013-10-10 2017-03-07 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
US20160338948A1 (en) * 2014-01-31 2016-11-24 Morishita Jintan Co., Ltd. Orally administered agent for ruminants and ruminant feed containing same
US10561631B2 (en) 2014-06-11 2020-02-18 Amarin Pharmaceuticals Ireland Limited Methods of reducing RLP-C
US10172818B2 (en) 2014-06-16 2019-01-08 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
US10406130B2 (en) 2016-03-15 2019-09-10 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
JP6884369B2 (ja) * 2016-12-28 2021-06-09 三生医薬株式会社 シームレスカプセル
WO2018213663A1 (en) 2017-05-19 2018-11-22 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject having reduced kidney function
US11058661B2 (en) 2018-03-02 2021-07-13 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L
DK4056176T3 (da) 2018-09-24 2024-05-06 Amarin Pharmaceuticals Ie Ltd Fremgangsmåde til at reducere risikoen af kardiovaskulære hændelser hos et individ
CN111040021B (zh) * 2018-10-12 2023-06-02 浙江道尔生物科技有限公司 一种改善生物活性蛋白性质的载体蛋白
JP6603817B1 (ja) 2019-01-18 2019-11-06 三生医薬株式会社 シ−ムレスカプセルならびにこれを含むフィルターおよび喫煙器具
KR20200105068A (ko) 2019-02-28 2020-09-07 우석대학교 산학협력단 오일을 함유하는 심리스 캡슐의 제조방법
US12427134B2 (en) 2019-11-12 2025-09-30 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of cardiovascular events in a subject with atrial fibrillation and/or atrial flutter
KR102204696B1 (ko) * 2019-12-10 2021-01-19 한국 한의학 연구원 1-모노에이코사펜타에노인을 유효성분으로 함유하는 주름개선용 조성물
WO2021201059A1 (ja) 2020-03-30 2021-10-07 三生医薬株式会社 メントールを含有する組成物
CN116507220A (zh) 2020-11-06 2023-07-28 学校法人近畿大学 血管疾病治疗用组合物、血管疾病预防用组合物、高血压治疗用组合物和高血压预防用组合物
JP6913976B1 (ja) * 2020-11-13 2021-08-04 東洋カプセル株式会社 シームレスカプセル及びその製造方法
WO2022225896A1 (en) 2021-04-21 2022-10-27 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of heart failure
AR127047A1 (es) 2021-09-14 2023-12-13 Sunsho Pharmaceutical Co Ltd Composición que contiene cariofileno
JPWO2023042819A1 (ja) 2021-09-14 2023-03-23
KR102864596B1 (ko) * 2022-04-25 2025-09-26 유엠에스엔지니어링 주식회사 오메가 3 심리스 연질캡슐 제조방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8819110D0 (en) * 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production
JP2806564B2 (ja) * 1989-07-20 1998-09-30 森下仁丹株式会社 親水性物質を内容物とするシームレスカプセルおよびその製法
JPH0412083A (ja) * 1990-04-27 1992-01-16 Osaka Titanium Co Ltd シリコン単結晶製造方法
JP3159724B2 (ja) 1991-04-19 2001-04-23 フロイント産業株式会社 シームレスカプセル製造方法および装置
JPH0826976A (ja) * 1994-07-21 1996-01-30 Freunt Ind Co Ltd 食品状医薬品
US5650232A (en) * 1994-10-07 1997-07-22 Warner-Lambert Company Method for making seamless capsules
JP3759986B2 (ja) * 1995-12-07 2006-03-29 フロイント産業株式会社 シームレスカプセルおよびその製造方法
ES2246769T3 (es) * 2000-05-22 2006-03-01 Pro Aparts - Investimentos E Consultoria Lda Composicion de acidos grasos que contiene al menos 80% en peso de epa y dha o sus derivados y su uso farmaceutico.
ATE340566T1 (de) * 2002-12-05 2006-10-15 Symrise Gmbh & Co Kg Nahtlose gefüllte kapseln
WO2004056370A1 (en) * 2002-12-20 2004-07-08 Pronova Biocare As Use of a fatty acid composition for treatment of male infertility
JP2004262774A (ja) * 2003-02-20 2004-09-24 Freunt Ind Co Ltd シームレスカプセル
GB0403247D0 (en) * 2004-02-13 2004-03-17 Tillotts Pharma Ag A pharmaceutical composition
JP2007523904A (ja) * 2004-02-17 2007-08-23 シムライズ・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング・ウント・コンパニー・コマンジツト・ゲゼルシヤフト 被覆された、球状のシームレス型充填カプセル
WO2008012329A2 (en) * 2006-07-28 2008-01-31 V. Mane Fils Seamless capsules containing high amounts of polyunsaturated fatty acids and a flavouring component

Also Published As

Publication number Publication date
KR20100039362A (ko) 2010-04-15
JP5047285B2 (ja) 2012-10-10
EP2172225A8 (en) 2011-06-29
WO2009004999A1 (ja) 2009-01-08
JPWO2009004999A1 (ja) 2010-08-26
AU2008272135B2 (en) 2013-10-31
ES2748934T3 (es) 2020-03-18
US20100119598A1 (en) 2010-05-13
AU2008272135A1 (en) 2009-01-08
CN102552213A (zh) 2012-07-11
CN101801416B (zh) 2012-10-24
TW200911358A (en) 2009-03-16
NZ582576A (en) 2012-05-25
CN101801416A (zh) 2010-08-11
EP2172225A1 (en) 2010-04-07
EP2172225A4 (en) 2011-04-27
EP2172225B1 (en) 2019-08-07
MY157882A (en) 2016-07-29

Similar Documents

Publication Publication Date Title
WO2009004999A1 (ja) シームレスカプセル
WO2009114601A3 (en) Preparation of lenalidomide
NO20084342L (no) Todelt transparent gummidannende silisiumblanding
WO2007143104A8 (en) Antibodies as t cell receptor mimics, methods of production and uses thereof
WO2008064353A3 (en) 7,8-saturated-4,5-epoxy-morphinanium analogs
WO2007143651A3 (en) Chewable co-enzyme q-10 capsule
PL1976933T3 (pl) Utwardzalna w temperaturze pokojowej kompozycja oragnopolisiloksanowa
WO2008091413A3 (en) Polycarbonate composition comprising nanomaterials
WO2010021962A3 (en) Azide-containing fluoropolymers and their preparation
WO2010007439A3 (en) Seal
EP2942599A3 (en) Composition suitable for a deflagration to detonation transition device
WO2010122332A3 (en) Xanthan gum and swellable particulate containing composition and uses thereof
WO2011053003A3 (en) Gastric-retentive sustained release formulation containing pregabalin, polyethyleneoxide and pva-peg graft copolymer
EP1976993A4 (en) THERMACETOGENIUM PHAEUM CONSORTIUM FOR THE MANUFACTURE OF MATERIALS WITH INCREASED HYDROGEN CONTENT
WO2010043408A3 (de) Mikroverkapseltes fesoterodin
WO2012075015A3 (en) Oral metronidazole pharmaceutical compositions
WO2011051967A3 (en) Pharmaceutical compositions comprising mycophenolate and processes for preparing thereof
WO2008099835A1 (ja) Ｐｅｇ充填硬質カプセル剤のバンドシール
WO2008065282A3 (fr) Pyrazoles substituees, compositions les contenant, procede de fabrication et utilisation
WO2008019782A3 (de) Dispersionen von nanoharnstoffen. enthaltend wirkstoffe
WO2009075329A1 (ja) 分解性を調整したゼラチン組成物
WO2008008548A3 (en) Engine with hybrid crankcase
WO2010128526A3 (en) Oxygen scavenging polyester composition
WO2011025386A3 (en) Marine housing for a submersible instrument
WO2006109344A3 (en) Composition to be used for the treatment of parodontal pathologies

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200880105165.8

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08790686

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2009521608

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 12009502459

Country of ref document: PH

WWE Wipo information: entry into national phase

Ref document number: 8341/DELNP/2009

Country of ref document: IN

Ref document number: 2008790686

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 12452374

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2008272135

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 582576

Country of ref document: NZ

ENP Entry into the national phase

Ref document number: 20107001925

Country of ref document: KR

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: 2008272135

Country of ref document: AU

Date of ref document: 20080627

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: PI 20095565

Country of ref document: MY