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WO2009044010A3 - Utilisation d'au moins un dérivé oxime de la cholest-4-èn-3-one comme antioxydants - Google Patents

Utilisation d'au moins un dérivé oxime de la cholest-4-èn-3-one comme antioxydants Download PDF

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Publication number
WO2009044010A3
WO2009044010A3 PCT/FR2008/001101 FR2008001101W WO2009044010A3 WO 2009044010 A3 WO2009044010 A3 WO 2009044010A3 FR 2008001101 W FR2008001101 W FR 2008001101W WO 2009044010 A3 WO2009044010 A3 WO 2009044010A3
Authority
WO
WIPO (PCT)
Prior art keywords
cholest
antioxidants
oxime derivative
food
oxime
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2008/001101
Other languages
English (en)
Other versions
WO2009044010A2 (fr
Inventor
Rebecca Pruss
Cyrille Drouot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Trophos SA
Original Assignee
Trophos SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CA2697125A priority Critical patent/CA2697125A1/fr
Priority to MX2010000915A priority patent/MX2010000915A/es
Priority to JP2010517450A priority patent/JP2010534227A/ja
Priority to BRPI0814580-6A2A priority patent/BRPI0814580A2/pt
Priority to RU2010106614/13A priority patent/RU2475052C2/ru
Priority to NZ582646A priority patent/NZ582646A/xx
Priority to EP08836563A priority patent/EP2173198A2/fr
Priority to AU2008306838A priority patent/AU2008306838A1/en
Application filed by Trophos SA filed Critical Trophos SA
Priority to US12/670,459 priority patent/US20100267680A1/en
Publication of WO2009044010A2 publication Critical patent/WO2009044010A2/fr
Publication of WO2009044010A3 publication Critical patent/WO2009044010A3/fr
Priority to ZA2010/00192A priority patent/ZA201000192B/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23BPRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00Preservation of foods or foodstuffs, in general
    • A23B2/70Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729Organic compounds; Microorganisms; Enzymes
    • A23B2/742Organic compounds containing oxygen
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23BPRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00Preservation of foods or foodstuffs, in general
    • A23B2/70Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729Organic compounds; Microorganisms; Enzymes
    • A23B2/762Organic compounds containing nitrogen
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23BPRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B70/00Preservation of non-alcoholic beverages
    • A23B70/10Preservation of non-alcoholic beverages by addition of preservatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings or cooking oils
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/18Antioxidants, e.g. antiradicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/522Antioxidants; Radical scavengers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Toxicology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

L'invention concerne l'utilisation d'au moins un dérivé oxime de la cholest-4- èn-3-one comme antioxydants dans les domaines cosmétiques et alimentaires, et comme conservateurs antioxydant utilisables notamment dans des produits cosmétiques, alimentaires, et pharmaceutiques.
PCT/FR2008/001101 2007-07-25 2008-07-24 Utilisation d'au moins un dérivé oxime de la cholest-4-èn-3-one comme antioxydants Ceased WO2009044010A2 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
EP08836563A EP2173198A2 (fr) 2007-07-25 2008-07-24 Utilisation d'au moins un dérivé oxime de la cholest-4-èn-3-one comme antioxydants
JP2010517450A JP2010534227A (ja) 2007-07-25 2008-07-24 少なくとも1つのコレスト−4−エン−3−オンオキシム誘導体の酸化防止剤としての使用
BRPI0814580-6A2A BRPI0814580A2 (pt) 2007-07-25 2008-07-24 Utilização de pelo menos um derivado de oxima da colest-4-en-3-ona ou um dos seus sais de adição com ácidos aceitáveis, ou de um dos seus ésteres ou de um dos sais de adição dos referidos ésteres com os ácidos aceitáveis
RU2010106614/13A RU2475052C2 (ru) 2007-07-25 2008-07-24 Применение по меньшей мере одного производного оксима холест-4-ен-3-она в качестве антиоксиданта
NZ582646A NZ582646A (en) 2007-07-25 2008-07-24 Use of at least one oxime derivative of cholest-4-en-3-one as antioxidants
CA2697125A CA2697125A1 (fr) 2007-07-25 2008-07-24 Utilisation d'au moins un derive oxime de la cholest-4-en-3-one comme antioxydants
MX2010000915A MX2010000915A (es) 2007-07-25 2008-07-24 Uso de cuando menos un derivado de oxima de colest-4-en-3-ona como antioxidantes.
AU2008306838A AU2008306838A1 (en) 2007-07-25 2008-07-24 Use of at least one oxime derivative of cholest-4-en-3-one as antioxidants
US12/670,459 US20100267680A1 (en) 2007-07-25 2008-07-24 Use of at least one oxime derivative of cholest-4-en-3-one as antioxidants
ZA2010/00192A ZA201000192B (en) 2007-07-25 2010-01-11 Use of at least one oxime derivative of cholest-4-en-3-one as antioxidants

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0705426 2007-07-25
FR0705426A FR2919180B1 (fr) 2007-07-25 2007-07-25 Utilisation d'au moins un derive oxime de la cholest-4-en-3-one comme antioxydants

Publications (2)

Publication Number Publication Date
WO2009044010A2 WO2009044010A2 (fr) 2009-04-09
WO2009044010A3 true WO2009044010A3 (fr) 2009-11-05

Family

ID=39167758

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2008/001101 Ceased WO2009044010A2 (fr) 2007-07-25 2008-07-24 Utilisation d'au moins un dérivé oxime de la cholest-4-èn-3-one comme antioxydants

Country Status (12)

Country Link
US (1) US20100267680A1 (fr)
EP (1) EP2173198A2 (fr)
JP (1) JP2010534227A (fr)
AU (1) AU2008306838A1 (fr)
BR (1) BRPI0814580A2 (fr)
CA (1) CA2697125A1 (fr)
FR (1) FR2919180B1 (fr)
MX (1) MX2010000915A (fr)
NZ (1) NZ582646A (fr)
RU (1) RU2475052C2 (fr)
WO (1) WO2009044010A2 (fr)
ZA (1) ZA201000192B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2874923B1 (fr) * 2004-09-07 2006-10-27 Trophos Sa Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation
FR2919182B1 (fr) * 2007-07-25 2009-11-13 Trophos Utilisation d'au moins un derive oxime du 3,5-seco-4-nor-cholestane comme antioxydants
FR2979239A1 (fr) 2011-08-25 2013-03-01 Trophos Liposome comprenant au moins un derive de cholesterol
CN109952286B (zh) * 2016-11-15 2022-03-22 香港浸会大学 基于石斛属成分的皮肤保护组合物
CN108113996A (zh) * 2016-11-29 2018-06-05 中国人民解放军军事医学科学院毒物药物研究所 一种用于化学毒剂防护的水溶性皮肤防护剂及其制备方法和用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61148111A (ja) * 1984-12-21 1986-07-05 Ichimaru Fuarukosu Kk 発毛促進剤
US20060217358A1 (en) * 2003-03-11 2006-09-28 Trophos Use of derivatives of cholest-4-en-3-one as medicaments, pharmaceutical compositions containing same, novel derivatives and preparation method thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU487923A1 (ru) * 1973-07-04 1975-10-15 Ордена Трудового Красного Знамени Институт Кристаллографии Им.А.В.Шубникова Стабильна жидкокристаллическа смесь
FR2581542B1 (fr) 1985-05-07 1988-02-19 Oreal Compositions topiques destinees au traitement de la peau a base de derives de l'acide salicylique
DE19834812A1 (de) * 1998-08-01 2000-02-03 Beiersdorf Ag Verwendung von Sterolderivaten in kosmetischen und dermatologischen Zubereitungen zur Stärkung der Barrierefunktion der Haut
FR2874923B1 (fr) * 2004-09-07 2006-10-27 Trophos Sa Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation
US20060198809A1 (en) * 2005-03-04 2006-09-07 Woodridge Labs, Inc. Gamma-amino butyric acid composition
FR2894968B1 (fr) 2005-12-20 2008-02-22 Trophos Sa Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation
FR2898272B1 (fr) * 2006-03-09 2008-07-04 Trophos Sa Utilisation de derives du 3,5-seco-4-nor-cholestrane pour l'obtention d'un medicament cytoprotecteur
FR2899108B1 (fr) * 2006-03-31 2012-02-03 Trophos Utilisation de derives du cholest-4-en-3-one pour l'obtention d'un medicament cytoprotecteur
FR2914188B1 (fr) * 2007-03-28 2012-06-22 Trophos Nouvelle composition a base d'oxime de cholest-4-en-3-one
FR2919182B1 (fr) * 2007-07-25 2009-11-13 Trophos Utilisation d'au moins un derive oxime du 3,5-seco-4-nor-cholestane comme antioxydants
RU2485956C2 (ru) * 2007-10-30 2013-06-27 Трофо Новая композиция для лечения побочных эффектов противораковой терапии
FR2934596B1 (fr) * 2008-07-30 2015-04-10 Trophos Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation
FR2940650B1 (fr) * 2008-12-29 2017-01-27 Trophos Nouveaux derives d'oxime du 3,5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant,et procede de preparation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61148111A (ja) * 1984-12-21 1986-07-05 Ichimaru Fuarukosu Kk 発毛促進剤
US20060217358A1 (en) * 2003-03-11 2006-09-28 Trophos Use of derivatives of cholest-4-en-3-one as medicaments, pharmaceutical compositions containing same, novel derivatives and preparation method thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 198633, Derwent World Patents Index; AN 1986-216089, XP002544222 *
KOBAYASHI M ET AL: "POLYPHOSPHORIC ACID-CATALYZED BECKMANN REARRANGEMENT OF 3-KETO-STEROID OXIMES", 1969, CHEMICAL AND PHARMACEUTICAL BULLETIN, TOKYO, JP, PAGE(S) 1255-1260, ISSN: 0009-2363, XP008029833 *
KOLAK U ET AL: "CARDIOACTIVE DITERPENOIDS FROM THE ROOTS OF SALVIA AMPLEXICAULIS", 2001, PLANTA MEDICA, THIEME, STUTTGART, DE, PAGE(S) 761-763, ISSN: 0032-0943, XP008033781 *
SUZUKI K ET AL: "The cholesterol metabolite cholest-4-en-3-one and its 3-oxo derivatives suppress body weight gain, body fat accumulation and serum lipid concentration in mice", 18 August 1998, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, PAGE(S) 2133-2138, ISSN: 0960-894X, XP004137233 *

Also Published As

Publication number Publication date
NZ582646A (en) 2012-11-30
RU2010106614A (ru) 2011-08-27
ZA201000192B (en) 2011-05-25
AU2008306838A1 (en) 2009-04-09
US20100267680A1 (en) 2010-10-21
BRPI0814580A2 (pt) 2014-10-07
WO2009044010A2 (fr) 2009-04-09
CA2697125A1 (fr) 2009-04-09
RU2475052C2 (ru) 2013-02-20
FR2919180B1 (fr) 2009-11-27
EP2173198A2 (fr) 2010-04-14
FR2919180A1 (fr) 2009-01-30
MX2010000915A (es) 2010-03-01
JP2010534227A (ja) 2010-11-04

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