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WO2008111507A1 - 改変されたグルコサミン-6-リン酸合成酵素 - Google Patents

改変されたグルコサミン-6-リン酸合成酵素 Download PDF

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Publication number
WO2008111507A1
WO2008111507A1 PCT/JP2008/054144 JP2008054144W WO2008111507A1 WO 2008111507 A1 WO2008111507 A1 WO 2008111507A1 JP 2008054144 W JP2008054144 W JP 2008054144W WO 2008111507 A1 WO2008111507 A1 WO 2008111507A1
Authority
WO
WIPO (PCT)
Prior art keywords
glucosamine
phosphate synthase
phosphate
modified glucosamine
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/054144
Other languages
English (en)
French (fr)
Inventor
Kouichi Terazono
Yoshiyuki Yonetani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyowa Hakko Bio Co Ltd
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Kyowa Hakko Bio Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd, Kyowa Hakko Bio Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of WO2008111507A1 publication Critical patent/WO2008111507A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

　本発明によれば、フラクトース-6-リン酸とアンモニアからグルコサミン-6-リン酸を精製する活性を有する蛋白質、該蛋白質をコードするDNA、該DNAを含む組換え体DNA、該蛋白質を製造する能力を有する微生物および該微生物を用いたグルコサミンまたはグルコサミン-6-リン酸の製造法を提供することができる。
PCT/JP2008/054144 2007-03-09 2008-03-07 改変されたグルコサミン-6-リン酸合成酵素 Ceased WO2008111507A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-060104 2007-03-09
JP2007060104 2007-03-09

Publications (1)

Publication Number Publication Date
WO2008111507A1 true WO2008111507A1 (ja) 2008-09-18

Family

ID=39759446

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/054144 Ceased WO2008111507A1 (ja) 2007-03-09 2008-03-07 改変されたグルコサミン-6-リン酸合成酵素

Country Status (1)

Country Link
WO (1) WO2008111507A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112048486A (zh) * 2020-07-23 2020-12-08 中国水产科学研究院南海水产研究所 一种斑节对虾PmGFPT2基因及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000004182A1 (en) * 1998-07-15 2000-01-27 Dcv, Inc. D/B/A Bio-Technical Resources Process and materials for production of glucosamine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000004182A1 (en) * 1998-07-15 2000-01-27 Dcv, Inc. D/B/A Bio-Technical Resources Process and materials for production of glucosamine

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DENG M.-D. ET AL.: "Directed evolution and characterization of Escherichia coli glucosamine synthase", BIOCHIMIE, vol. 88, no. 5, 2006, pages 419 - 429, XP005507361 *
MOUILLERON S. ET AL.: "Glutamine Binding Opens the Ammonia Channel and Activates Glucosamine-6P Synthase", J. BIOL. CHEM., vol. 281, no. 7, 2006, pages 4404 - 4412 *
TEPLYAKOV A. ET AL.: "Channeling of ammonia in glucosamine-6-phosphate synthase", JOURNAL OF MOLECULAR BIOLOGY, vol. 313, no. 5, 2001, pages 1093 - 1102, XP004469295 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112048486A (zh) * 2020-07-23 2020-12-08 中国水产科学研究院南海水产研究所 一种斑节对虾PmGFPT2基因及其应用
CN112048486B (zh) * 2020-07-23 2021-11-09 中国水产科学研究院南海水产研究所 一种斑节对虾PmGFPT2基因及其应用

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