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WO2008102192A3 - Controlled release pharmaceutical compositions - Google Patents

Controlled release pharmaceutical compositions Download PDF

Info

Publication number
WO2008102192A3
WO2008102192A3 PCT/HU2008/000020 HU2008000020W WO2008102192A3 WO 2008102192 A3 WO2008102192 A3 WO 2008102192A3 HU 2008000020 W HU2008000020 W HU 2008000020W WO 2008102192 A3 WO2008102192 A3 WO 2008102192A3
Authority
WO
WIPO (PCT)
Prior art keywords
controlled release
release pharmaceutical
layer
pharmaceutical compositions
primery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/HU2008/000020
Other languages
French (fr)
Other versions
WO2008102192A2 (en
Inventor
Pal Fekete
Zoltan Budavari
Gyoergy Ujfalussy
Zsolt Zsigmond
Agnes Bozso
Huszar Magdolna Leventiszne
Zoltanne Palfi
Krisztina Abraham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egis Pharmaceuticals PLC
Original Assignee
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egis Pharmaceuticals PLC filed Critical Egis Pharmaceuticals PLC
Publication of WO2008102192A2 publication Critical patent/WO2008102192A2/en
Publication of WO2008102192A3 publication Critical patent/WO2008102192A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to a controlled release pharmaceutical composition in a layered pellet form containing carvedilol, wherein the pellet contains a core (1) containing a solid organic acid, a primery coating layer (2), an acid dissolution controlling layer (3), a layer (4) containing the active ingredient and a further enteric layer (5).
PCT/HU2008/000020 2007-02-23 2008-02-22 Controlled release pharmaceutical compositions Ceased WO2008102192A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU0700172A HU227881B1 (en) 2007-02-23 2007-02-23 Sustained release pharmaceutical preparation containing carvedilol
HUP0700172 2007-02-23

Publications (2)

Publication Number Publication Date
WO2008102192A2 WO2008102192A2 (en) 2008-08-28
WO2008102192A3 true WO2008102192A3 (en) 2009-04-09

Family

ID=89987354

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/HU2008/000020 Ceased WO2008102192A2 (en) 2007-02-23 2008-02-22 Controlled release pharmaceutical compositions

Country Status (2)

Country Link
HU (1) HU227881B1 (en)
WO (1) WO2008102192A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002065834A2 (en) * 2000-10-24 2002-08-29 Smithkline Beecham Corporation Novel formulations of carvedilol
WO2003074032A1 (en) * 2002-03-07 2003-09-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Oral administration form for difficulty soluble basic active ingredients which are applied orally
WO2004056336A2 (en) * 2002-12-20 2004-07-08 Ranbaxy Laboratories Limited Controlled release, multiple unit drug delivery systems
WO2006102964A2 (en) * 2005-03-29 2006-10-05 Evonik Röhm Gmbh Multiparticulate pharmaceutical form comprising pellets with a substance having a modular effect in relation to active ingredient release
WO2007023325A2 (en) * 2005-08-26 2007-03-01 Egis Gyógyszergyár Nylvánosan Müködo Részvénytársaság Controlled release pharmaceutical composition containing carvedilol

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002065834A2 (en) * 2000-10-24 2002-08-29 Smithkline Beecham Corporation Novel formulations of carvedilol
WO2003074032A1 (en) * 2002-03-07 2003-09-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Oral administration form for difficulty soluble basic active ingredients which are applied orally
WO2004056336A2 (en) * 2002-12-20 2004-07-08 Ranbaxy Laboratories Limited Controlled release, multiple unit drug delivery systems
WO2006102964A2 (en) * 2005-03-29 2006-10-05 Evonik Röhm Gmbh Multiparticulate pharmaceutical form comprising pellets with a substance having a modular effect in relation to active ingredient release
WO2007023325A2 (en) * 2005-08-26 2007-03-01 Egis Gyógyszergyár Nylvánosan Müködo Részvénytársaság Controlled release pharmaceutical composition containing carvedilol

Also Published As

Publication number Publication date
HU227881B1 (en) 2012-05-29
WO2008102192A2 (en) 2008-08-28
HUP0700172A3 (en) 2010-01-28
HU0700172D0 (en) 2008-03-28
HUP0700172A2 (en) 2008-12-29

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