[go: up one dir, main page]

WO2008038149A3 - Process for production of cytidine 5'-monophosphate - Google Patents

Process for production of cytidine 5'-monophosphate Download PDF

Info

Publication number
WO2008038149A3
WO2008038149A3 PCT/IB2007/003807 IB2007003807W WO2008038149A3 WO 2008038149 A3 WO2008038149 A3 WO 2008038149A3 IB 2007003807 W IB2007003807 W IB 2007003807W WO 2008038149 A3 WO2008038149 A3 WO 2008038149A3
Authority
WO
WIPO (PCT)
Prior art keywords
amino acid
monophosphate
protein
cytidine
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2007/003807
Other languages
French (fr)
Japanese (ja)
Other versions
WO2008038149A2 (en
Inventor
Hisaya Tanaka
Akihiko Maruyama
Yoshiyuki Yonetani
Ritsuko Katahira
Shingo Kakita
Satoshi Mitsuhashi
Jun-Ichi Saito
Hideki Oda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP2008536202A priority Critical patent/JP5175734B2/en
Publication of WO2008038149A2 publication Critical patent/WO2008038149A2/en
Publication of WO2008038149A3 publication Critical patent/WO2008038149A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1077—Pentosyltransferases (2.4.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Disclosed is a protein having an activity of producing cytidine 5'-monophosphate (CMP) from cytosine. Specifically disclosed is: a protein having an amino acid sequence depicted in SEQ ID NO:1, 2 or 30; or a protein which has an amino acid sequence having the substitution of at least one amino acid residue selected from amino acid residues at the 36th, 46th, 94th, 102nd, 121st, 141st, 143rd, 167th and 198th positions in an amino acid sequence depicted in SEQ ID NO:1, 2 or 30 by a different amino acid residue.
PCT/IB2007/003807 2006-09-27 2007-09-27 Process for production of cytidine 5'-monophosphate Ceased WO2008038149A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008536202A JP5175734B2 (en) 2006-09-27 2007-09-27 Method for producing cytidine 5'-monophosphate

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006262666 2006-09-27
JP2006-262666 2006-09-27

Publications (2)

Publication Number Publication Date
WO2008038149A2 WO2008038149A2 (en) 2008-04-03
WO2008038149A3 true WO2008038149A3 (en) 2008-11-13

Family

ID=39230606

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/003807 Ceased WO2008038149A2 (en) 2006-09-27 2007-09-27 Process for production of cytidine 5'-monophosphate

Country Status (2)

Country Link
JP (1) JP5175734B2 (en)
WO (1) WO2008038149A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7693230B2 (en) 1999-04-16 2010-04-06 Parkervision, Inc. Apparatus and method of differential IQ frequency up-conversion
US7072427B2 (en) 2001-11-09 2006-07-04 Parkervision, Inc. Method and apparatus for reducing DC offsets in a communication system

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005108562A2 (en) * 2004-05-10 2005-11-17 Fondazione Centro San Raffaele Del Monte Tabor Synthetic fluorouridine-activating enzyme for cancer therapy

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005108562A2 (en) * 2004-05-10 2005-11-17 Fondazione Centro San Raffaele Del Monte Tabor Synthetic fluorouridine-activating enzyme for cancer therapy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
FURTH J. J. ET AL.: "The incorporation of adenylic and cytidylic acids into ribonucleic acid", J. BIOL. CHEM., vol. 236, 1961, pages 3317 - 3322, XP055354130 *

Also Published As

Publication number Publication date
WO2008038149A2 (en) 2008-04-03
JP5175734B2 (en) 2013-04-03
JPWO2008038149A1 (en) 2010-01-28

Similar Documents

Publication Publication Date Title
NZ591416A (en) Antisense oligonucleotides directed against connective tissue growth factor and uses thereof
WO2004072100A3 (en) Nell peptide expression systems and bone formation activity of nell peptide
NZ598724A (en) Soybean transgenic event mon 87708 and methods of use thereof
TW200726777A (en) Peptides inhibiting angiotensin-converting enzyme
NZ600690A (en) Fkbp-l and uses thereof
WO2003091398A3 (en) Compositions and methods for stem cell delivery
EP3249405A3 (en) Stabilizing composition for immobilized biomolecules
IL265947A (en) High-purity large-scale preparation of stannsoporfin
WO2008109142A3 (en) Pirna and uses related thereto
MY150072A (en) Mucosal bioadhesive slow release carrier for delivering active principles
MX2009010965A (en) Tem8 peptides and vaccines comprising the same.
WO2008038149A3 (en) Process for production of cytidine 5'-monophosphate
ATE453719T1 (en) GLYCOSYLATED HYBRID COMPOUNDS, THEIR PRODUCTION AND USE
IL175319A (en) Phosphate-binding protein, compositions comprising it, use thereof and method for detecting the same
WO2002077277A3 (en) Dna markers for assessing seed purity and a method of using dna sequences for assessing seed purity
WO2004022715A3 (en) Cloning and characterization of the broad-spectrum resistance gene pi2
WO2005082155A3 (en) A method for the preparation of a high-purity rice protein concentrate
TW200633977A (en) Novel process for the manufacture of 3-pyrrolidin-2-yl-propionic acid derivatives
WO2009044085A3 (en) Oligonucleotides, use, method of detection and kit for diagnosing the presence of the e1 gene of the chikungunya virus
KR100399333B1 (en) Novel genotype cms radish family plant, method for producing hybrid seeds using the same, and dna marker for selecting the nwb-cms radish family plant
WO2007023342A3 (en) Process of making geminal bisphosphonic acids and pharmaceutically acceptable salts and/or hydrates thereof
WO2008155924A1 (en) Glucose dehydrogenase
WO2009108513A3 (en) Methods and compositions for increased yield
WO2008041176A3 (en) Process for the preparation of form i and form ii of ritonavir
WO2006102657A3 (en) Method of protecting a soybean plant with flutriafol

Legal Events

Date Code Title Description
DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07825771

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2008536202

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 07825771

Country of ref document: EP

Kind code of ref document: A2

DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)