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WO2008017456A1 - Système de perfusion comprenant un mélange réactionnel pour modifier la température d'un liquide de perfusion - Google Patents

Système de perfusion comprenant un mélange réactionnel pour modifier la température d'un liquide de perfusion Download PDF

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Publication number
WO2008017456A1
WO2008017456A1 PCT/EP2007/006973 EP2007006973W WO2008017456A1 WO 2008017456 A1 WO2008017456 A1 WO 2008017456A1 EP 2007006973 W EP2007006973 W EP 2007006973W WO 2008017456 A1 WO2008017456 A1 WO 2008017456A1
Authority
WO
WIPO (PCT)
Prior art keywords
infusion
reaction
tube
liquid
reservoir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2007/006973
Other languages
German (de)
English (en)
Inventor
Fabian Temme
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2008017456A1 publication Critical patent/WO2008017456A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K5/00—Heat-transfer, heat-exchange or heat-storage materials, e.g. refrigerants; Materials for the production of heat or cold by chemical reactions other than by combustion
    • C09K5/16—Materials undergoing chemical reactions when used
    • C09K5/18—Non-reversible chemical reactions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D5/00—Devices using endothermic chemical reactions, e.g. using frigorific mixtures
    • F25D5/02—Devices using endothermic chemical reactions, e.g. using frigorific mixtures portable, i.e. adapted to be carried personally
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M2005/14272—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body for emergency, field or home use, e.g. self-contained kits to be carried by the doctor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3606—General characteristics of the apparatus related to heating or cooling cooled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/364—General characteristics of the apparatus related to heating or cooling by chemical reaction
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2331/00—Details or arrangements of other cooling or freezing apparatus not provided for in other groups of this subclass
    • F25D2331/80—Type of cooled receptacles
    • F25D2331/811—Pour-throughs

Definitions

  • the invention relates to a portable infusion system having at least one infusion tube for connecting at least one infusion reservoir having an infusion liquid to an access to the human or animal body, wherein in an infusion the infusion solution flows from the infusion reservoir through the infusion tube to the body.
  • the invention relates to a method for cooling infusion fluid.
  • BESTATIGUNGSKOPIE In addition, there is a problem in that it is not possible to store the infusion liquid too cold to supply them directly to the patient. Before the infusion liquid is heated, for example, to a body inlet temperature of 32 to 34 0 C, which requires appropriate Schuein- devices. However, similar heaters are also usually not available locally.
  • the object of the present invention is to provide a transportable infusion system which enables a temperature control of infusion fluid in a simple and cost-effective manner.
  • a temperature difference when cooling or heating the infusion solution of at least 5 to 10 0 C can be achieved with the infusion system according to the invention.
  • the temperature of the infusion liquid is changed by indirect heat transfer between the infusion liquid and at least one reaction mixture, wherein the reaction mixture is obtainable by mixing at least two reaction components and wherein a enthalpy change of the reaction mixture in the reaction of the reaction components to the temperature change the infusion fluid leads.
  • the invention allows, if necessary, to provide several reactions in order to ensure a targeted temperature of the infusion liquid.
  • a regulation of the temperature of the infusion liquid is conceivable such that a suitable reaction mixture is present, which cools the infusion liquid from a temperature of 37 0 C and heated to 34 0 C.
  • reaction in the context of the invention includes physicochemical and chemical reactions.
  • reaction for cooling the infusion liquid, it is possible to use, for example, freeze mixtures of at least two reaction components, heat being able to be removed by an endothermic reaction of the components of the infusion liquid.
  • endothermic heat effects can be utilized in dissolving the salts for cooling.
  • the temperature change during dissolution results from the energy required to dissolve the ion lattice of the salts and the hydration energy, which is released upon dissolution.
  • the mixture of the environment extracts the missing energy, the solution cools down.
  • Cold mixes of salts in water can reach temperatures of up to -15 ° C.
  • the infusion liquid is instead provided to exploit the released during an exothermic reaction of at least two reaction components released heat energy.
  • systems of at least two reaction components for heating the infusion fluid can be provided, which are used in the prior art, for example in the case of latent heat accumulators.
  • the invention allows hypothermia induction by infusion of cold fluids directly on site. Pre-cooling of the infusion solution in a refrigerator or the like is not required.
  • the infusion system according to the invention can therefore be used locally and independently of the availability of electrical energy for cooling or heating the infusion solution.
  • the reaction mixture is obtained in the infusion system according to the invention by two initially separately present reaction components, which are then mixed. After mixing, the physicochemical or chemical reaction occurs, for example, for the dissociation reaction of salts in water.
  • the decrease in the total enthalpy occurring in the latter reaction between the reaction components then leads to a cooling of the infusion liquid, which presupposes that the available heat transfer surface between the Inrusi- onswashkeit and the reaction mixture is sufficiently large to ensure indirect heat transfer to the extent required.
  • the temperature change of the infusion solution should take place when flowing through the infusion tube.
  • the infusion liquid stored in the infusion reservoir could also be chemically induced to cool or heat up before passing through the infusion tube, which, however, necessitates a longer cooling time or a greater temperature difference.
  • At least a first reservoir for at least a first reaction component and at least a second reservoir for at least a second reaction component are provided, wherein the first reservoir and the second reservoir are separated from each other in a non-use state of the infusion system and wherein Use state of the infusion system for a change in temperature of the infusion fluid at least one fluid-communicating connection between the first reservoir and the second reservoir can be produced.
  • About the fluid-communicating compound the mixing of the two components to the reaction mixture, which occurs during mixing and then to the described endothermic or exothermic reaction.
  • the separation of the two reservoirs in the non-use state ensures that the infusion system according to the invention remains usable over a long period of time.
  • At least one jacket tube surrounding the infusion tube is provided, wherein between the infusion tube and the jacket tube Mantle space for the endothermic or exothermic reaction of the reaction components is formed.
  • the jacket space extends in the manner of an annular gap preferably substantially over the entire length of the infusion tube, wherein the jacket tube can be glued and / or fused at its upper end and at its lower end to the infusion tube and wherein the jacket tube can have the same length as the infusion tube.
  • the jacket space between the jacket tube and the infusion tube is preferably closed to the outside, so that an outlet of a reaction component from the shell space must be feared neither in the non-use state nor in use.
  • the jacket space may have a first chamber for the first reaction component towards the distal end of the infusion tube and a second chamber for the second reaction component towards the proximal end of the infusion tube, wherein in the non-use state of the infusion system, the first chamber and the second chamber by at least a liquid-tight partition are separated from each other.
  • the infusion tube is guided through the two chambers in the longitudinal direction.
  • a plurality of chambers for the first reaction component and a plurality of chambers for the second reaction component may also be arranged alternately one behind the other in order to ensure improved mixing of the reaction components.
  • the chambers are then separated from one another.
  • the reaction components can be mixed in a simple manner and initiate the endothermic or exothermic reaction, wherein the mixing of the components can be further enhanced by the influence of gravity and / or by diffusion effects.
  • a mechanical interruption of the partition for example by piercing a needle or the like., Is possible. Then, however, it must be ensured that there is no escape of a reaction component via the jacket tube into the environment or to a perforation of the infusion tube and contamination of the infusion liquid.
  • the infusion liquid is supplied in the case of a hanging arrangement of the infusion tube, whereby the infusion liquid is conducted from a suspended container or bag via the hanging infusion tube to the body.
  • a reaction space for the endothermic or exothermic reaction is preferably formed by the lower chamber. In principle, however, the reaction can also take place in both chambers.
  • the dividing wall is interrupted by exerting pressure on the first chamber arranged above the dividing wall, the reaction component contained in the first chamber exits via the dividing wall into the second chamber arranged below it.
  • the dividing wall is preferably arranged adjacent to the distal end of the infusion tube.
  • a sufficiently long cooling section for the infusion solution By displacing the dividing wall to the distal end of the infusion tube, a sufficiently long cooling section for the infusion solution can be provided, wherein the length of the cooling section can correspond to the length of the second second chamber arranged below the dividing wall.
  • the Distance of the partition from the distal end of the infusion tube less than 15 cm, in particular less than 5 to 10 cm, amount.
  • the two chambers preferably have a different cavity volume, which takes into account the fact that the amounts used of the reaction components are generally not the same size.
  • a comparatively small amount of liquid water suffices to dissolve a large amount of a salt.
  • a reservoir for the first reaction component with the shell space which is formed between the infusion tube and the outer jacket tube, via at least one closed in non-use state fluidkommuniticiande line, such as a hose connected wherein the entire shell space can form a reservoir for the second reaction component.
  • the first reservoir is thus separated from the jacket space and connected, for example via a closable conduit with the jacket space.
  • the first reservoir may be a bag or a container for a reaction component, wherein the contents of the bag or container may be emptied into the jacket space after opening the conduit.
  • the desired reaction of the components wherein the shell space over its entire length, i. preferably over the entire length of the infusion tube, for cooling or heating of the infusion solution is effective.
  • the invention also allows for liquid reaction components to provide two external fluid reservoirs for the components.
  • the components are then introduced together into the shell space, wherein in turn the mixing of the reaction components takes place in the shell space and the endothermic or exothermic reaction takes place.
  • the coolant in the invention can be effected by mixing a first liquid reaction component with a second solid reaction component, wherein the second reaction component can be in particular spherical or particulate.
  • the first reaction component is water and the second reaction component is a salt, as will be discussed below.
  • the first liquid reaction component can be arranged in the upper chamber.
  • the second reaction component can be stored.
  • the desired reaction then preferably occurs between the components, with the first component being emptied into the second chamber via the dividing wall between the chambers.
  • the void volume of the second reaction component in the second chamber should be sufficiently large to ensure intensive mixing with the first reaction component.
  • the first chamber is preferably designed to be correspondingly large in order to ensure a complete reaction of the two reaction components. This applies correspondingly if the jacket space has only one chamber as the reaction space and is completely filled with the second reaction component, wherein the first reaction component is introduced into the jacket space via an external bag or container.
  • reaction mixtures which are not obtainable by a mixture of a solid and a liquid reaction component.
  • both reaction components may be liquid or flowable.
  • the reaction component can be distributed uniformly over the entire length of a chamber. This ensures a uniform cooling effect over the entire length. The same applies if the shell space has only one chamber and is completely filled with a reaction component.
  • the first coolant component may comprise water and optionally further components
  • the second coolant component ammonium nitrate, in particular calcium ammonium nitrate, and optionally further components.
  • the mixing of ammonium nitrate in water leads to a dothermic dissolution reaction of the salt in water, which in its dissolution removes heat from the water and thereby causes a considerable decrease in temperature.
  • xylitol wood sugar
  • xylitol wood sugar
  • a second coolant component which is dissolved with an aqueous or nonaqueous liquid as the first coolant component.
  • the transition from a crystalline to a non-crystalline state, for example in dissolved form, takes place in the case of xylitol with the absorption of heat, whereby the energy required to dissolve the crystal lattice is removed from the environment, so that a temperature decrease occurs.
  • This cooling effect can in turn be used to cool the infusion fluid.
  • gases for example, can be incorporated into the second reaction component, which can lead to an increase in volume of the second reaction component present in spherical or particulate form. This makes it possible to fill the second chamber evenly with the second reaction component in the case of a high volume of voids. Moreover, it is also possible to mix the second reaction component with at least one porous material and to distribute it together with the porous material in the chamber. By the porous material can be ensured that the second reaction component evenly distributed. Also, sponge-like structures may be provided in the interior of the chamber, to which the second reaction component attaches.
  • the second reaction component may be attached to the inner wall of the jacket tube or to the outer wall of the infusion tube. Bonding of the second reaction component in the interior of the jacket space is also possible in order to keep the second reaction component in intermediate stages. In this case, however, it must be ensured that intensive mixing of the first and the second reaction component is still possible. Internals may also be provided in the inner area between the infusion tube and the jacket tube, which serve as a barrier for the second reaction component and prevent accumulation of the reaction component at the lower end of the chamber. It is understood that the features mentioned regardless of the training of the information system can be provided in order to achieve an even distribution of a component in a reservoir for this component.
  • reaction component with at least one further component which is rapidly soluble so that upon mixing with the other reaction component, flow in the reservoir occurs.
  • the currents ensure a uniform distribution of the reaction components. It is understood that said features can be provided independently of the formation of the infusion system in order to achieve an even distribution of the reaction components.
  • At least one reaction component comprises at least one thermochromic material
  • an end to the endothermic or exothermic reaction i. an end of the temperature change or the achievement of a certain temperature
  • the temperature can be indicated by the color of the thermochromic material.
  • the thermochromic material may be arranged, for example, in the interior of a particle or spherical reaction component.
  • the concentration of a thermochromic material inside a particulate or spherical reaction component may increase from the inside to the outside to indicate how long a temperature manipulation of the infusion fluid is still possible.
  • At least one protective tube may be provided between the infusion tube and the jacket tube, the protective tube being filled with a conducting liquid.
  • the protective tube provides adequate protection against contamination of the infusion fluid in the event of damage to the infusion tube.
  • the conductive fluid ensures good heat transfer between the infusion fluid and the reaction mixture. guaranteed.
  • at least one colorant may be provided to indicate a mixing of infusion solution and / or conducting liquid with at least one reaction component by color change.
  • at least one reaction component involved in the endothermic or exothermic reaction or the conducting liquid has a color-modifying component for this purpose.
  • the infusion tube can be made of PVC or PUR.
  • the jacket hose is preferably made of PE. This ensures a high resistance of the infusion system to mechanical damage and aging.
  • FIGURE of the drawing shows a transportable infusion system 1 with which an infusion liquid 2 can be supplied via an infusion tube 3 to an access 4 of a schematically represented human body 5.
  • the infusion liquid 2 flows from a bag-shaped or container-shaped infusion reservoir 6 through the infusion tube 3 to the body 5, wherein the infusion system 1 is arranged suspended and the volume flow through the infusion tube 3 can be adjusted by means of a regulator 7.
  • the infusion system 1 is used for cooling the infusion fluid 2.
  • the infusion tube 3 is guided inside a protective tube 8, which in turn is guided inside an outer jacket tube 9.
  • the inner region between the jacket tube 9 and the protective tube 8 forms a jacket space 10, which has a first chamber 11 and a second chamber 12.
  • the chambers 11, 12 are separated from each other by a partition wall 12a in the non-use state of the infusion system 1.
  • a first liquid reaction component 13 is provided, which is water.
  • the second chamber 12 has an ammonium nitrate-containing mixture, preferably calcium ammonium nitrate in granular form.
  • the second chamber 12 represents a reaction space for the dissociation reaction of ammonium nitrate in water.
  • the annular space between the infusion tube 3 and the protective tube 8 is filled with a conducting liquid 15 in order to facilitate the heat transfer from the infusion liquid 2 to the reaction mixture of the two reaction components 13, 14 in the second chamber 12.
  • the second reaction component 14 is arranged distributed substantially uniformly over the entire length of the second chamber 12. As a result, a uniform cooling effect can be ensured. It is understood that the first chamber 1 1 has a sufficient size to ensure the solution reaction of the second reaction component 14 sufficiently.

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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Combustion & Propulsion (AREA)
  • Thermal Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Mechanical Engineering (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un système de perfusion mobile (1), avec au moins un flexible de perfusion (3) pour relier au moins un réservoir de perfusion (6) comprenant un liquide de perfusion (2) à un accès (4) vers un corps humain ou animal (5). Lors d'une perfusion, le liquide de perfusion (2) s'écoule du réservoir de perfusion (6) vers le corps (5) par le flexible de perfusion (3). Selon l'invention, un transfert indirect de chaleur a lieu entre le liquide de perfusion (2) et au moins un mélange réactionnel, le mélange réactionnel pouvant être obtenu par mélange d'au moins deux composants réactifs (13, 14). La modification de l'enthalpie du mélange réactionnel lors de la réaction des composants réactifs (13, 14) engendre une modification de la température du liquide de perfusion (2).
PCT/EP2007/006973 2006-08-07 2007-08-07 Système de perfusion comprenant un mélange réactionnel pour modifier la température d'un liquide de perfusion Ceased WO2008017456A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE202006012186.2 2006-08-07
DE202006012186 2006-08-07

Publications (1)

Publication Number Publication Date
WO2008017456A1 true WO2008017456A1 (fr) 2008-02-14

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WO (1) WO2008017456A1 (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011103604A3 (fr) * 2010-02-21 2011-11-10 Rian Botes Dispositif de refroidissement d'une boisson
WO2012054973A1 (fr) 2010-10-27 2012-05-03 Flinders Medical Centre Chauffe-liquides portatif
CN103654997A (zh) * 2013-12-05 2014-03-26 凌浪 一种连续注射器
WO2014070798A1 (fr) 2012-10-29 2014-05-08 Forever Young International, Inc. Dispositifs d'administration de fluide intracorporel modifiant la température
CN103861183A (zh) * 2014-03-14 2014-06-18 重庆大学 一种利用相变实现热量转移的输液管加热装置
CN104162213A (zh) * 2014-08-27 2014-11-26 苏州万木春生物技术有限公司 一种快速流体冷却装置
WO2018025107A1 (fr) 2016-08-04 2018-02-08 Frasnelli Andreas Appareil intraveineux auto-chauffant
CN108744174A (zh) * 2018-06-15 2018-11-06 河南省肿瘤医院 一种静脉输液固定装置
EP4056155A1 (fr) * 2016-11-02 2022-09-14 Miraki Innovation Think Tank, LLC Dispositifs et procédés de génération de boue

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522190A (en) * 1983-11-03 1985-06-11 University Of Cincinnati Flexible electrochemical heater
DE3444066A1 (de) * 1984-12-03 1986-06-05 Kneipp-Werke Kneipp-Mittel-Zentrale Leusser & Oberhäußer, 8700 Würzburg Packung fuer die heilbehandlung durch energiezufuhr oder -entzug
GB2233081A (en) * 1989-04-15 1991-01-02 Richard Cedric Hart Jones Heating or cooling device
FI896072A7 (fi) * 1989-12-19 1991-06-20 Bo Roger Boedeker Transfusions och infusionsvaetskevaermare.
GB2316159A (en) * 1996-08-03 1998-02-18 Bass Plc Cooling packaged beverages
EP1201257A1 (fr) * 2000-10-18 2002-05-02 Anders Magnusson Procédé et dispositif pour maintenir au chaud des liquides de perfusion
WO2003059414A2 (fr) * 2002-01-15 2003-07-24 The Heat Factory, Inc. Dispositif de rechauffement pour fluide destine a une administration par voie intraveineuse
DE202004009808U1 (de) * 2004-06-22 2004-10-14 Wang, Wei-Hsun, Yungho Thermochrome Wärmespeicher-/Freigabevorrichtung
EP1584341A1 (fr) * 2004-04-08 2005-10-12 Sidam di Azzolini Graziano E C. S.a.s. Ensemble pour injecter des fluides conditionnées thermiquement, en particulier pour des interventions de premiers soins
WO2006056015A1 (fr) * 2004-11-26 2006-06-01 Flinders Medical Centre Rechauffeur de fluides
WO2006074260A1 (fr) * 2005-01-07 2006-07-13 Hickey, Charles P. Emballage destine a rechauffer ou a refroidir un produit alimentaire

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522190A (en) * 1983-11-03 1985-06-11 University Of Cincinnati Flexible electrochemical heater
DE3444066A1 (de) * 1984-12-03 1986-06-05 Kneipp-Werke Kneipp-Mittel-Zentrale Leusser & Oberhäußer, 8700 Würzburg Packung fuer die heilbehandlung durch energiezufuhr oder -entzug
GB2233081A (en) * 1989-04-15 1991-01-02 Richard Cedric Hart Jones Heating or cooling device
FI896072A7 (fi) * 1989-12-19 1991-06-20 Bo Roger Boedeker Transfusions och infusionsvaetskevaermare.
GB2316159A (en) * 1996-08-03 1998-02-18 Bass Plc Cooling packaged beverages
EP1201257A1 (fr) * 2000-10-18 2002-05-02 Anders Magnusson Procédé et dispositif pour maintenir au chaud des liquides de perfusion
WO2003059414A2 (fr) * 2002-01-15 2003-07-24 The Heat Factory, Inc. Dispositif de rechauffement pour fluide destine a une administration par voie intraveineuse
EP1584341A1 (fr) * 2004-04-08 2005-10-12 Sidam di Azzolini Graziano E C. S.a.s. Ensemble pour injecter des fluides conditionnées thermiquement, en particulier pour des interventions de premiers soins
DE202004009808U1 (de) * 2004-06-22 2004-10-14 Wang, Wei-Hsun, Yungho Thermochrome Wärmespeicher-/Freigabevorrichtung
WO2006056015A1 (fr) * 2004-11-26 2006-06-01 Flinders Medical Centre Rechauffeur de fluides
WO2006074260A1 (fr) * 2005-01-07 2006-07-13 Hickey, Charles P. Emballage destine a rechauffer ou a refroidir un produit alimentaire

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011103604A3 (fr) * 2010-02-21 2011-11-10 Rian Botes Dispositif de refroidissement d'une boisson
US9962501B2 (en) 2010-10-27 2018-05-08 Fbe Pty Ltd Portable fluid warmer
WO2012054973A1 (fr) 2010-10-27 2012-05-03 Flinders Medical Centre Chauffe-liquides portatif
US20130267930A1 (en) * 2010-10-27 2013-10-10 Fbe Pty Ltd Portable fluid warmer
US10744276B2 (en) 2010-10-27 2020-08-18 Fbe Pty Ltd Portable fluid warmer
EP2911720B1 (fr) * 2012-10-29 2020-01-08 Forever Young International, Inc. Dispositifs d'administration de fluide intracorporel modifiant la température
WO2014070798A1 (fr) 2012-10-29 2014-05-08 Forever Young International, Inc. Dispositifs d'administration de fluide intracorporel modifiant la température
CN103654997B (zh) * 2013-12-05 2015-09-23 凌浪 一种连续注射器
CN103654997A (zh) * 2013-12-05 2014-03-26 凌浪 一种连续注射器
CN103861183B (zh) * 2014-03-14 2015-11-04 重庆大学 一种利用相变实现热量转移的输液管加热装置
CN103861183A (zh) * 2014-03-14 2014-06-18 重庆大学 一种利用相变实现热量转移的输液管加热装置
CN104162213A (zh) * 2014-08-27 2014-11-26 苏州万木春生物技术有限公司 一种快速流体冷却装置
WO2018025107A1 (fr) 2016-08-04 2018-02-08 Frasnelli Andreas Appareil intraveineux auto-chauffant
EP4056155A1 (fr) * 2016-11-02 2022-09-14 Miraki Innovation Think Tank, LLC Dispositifs et procédés de génération de boue
US11890225B2 (en) 2016-11-02 2024-02-06 Miraki Innovation Think Tank Llc Devices and methods for slurry generation
CN108744174A (zh) * 2018-06-15 2018-11-06 河南省肿瘤医院 一种静脉输液固定装置

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