WO2008016995A3 - Procédés d'identification de modulateurs de la signalisation de l'insuline - Google Patents
Procédés d'identification de modulateurs de la signalisation de l'insuline Download PDFInfo
- Publication number
- WO2008016995A3 WO2008016995A3 PCT/US2007/075001 US2007075001W WO2008016995A3 WO 2008016995 A3 WO2008016995 A3 WO 2008016995A3 US 2007075001 W US2007075001 W US 2007075001W WO 2008016995 A3 WO2008016995 A3 WO 2008016995A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- identifying modulators
- insulin signalling
- insulin
- signalling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Cette invention concerne des procédés d'identification de médicaments pour le traitement de la résistance à l'insuline et du diabète.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82111806P | 2006-08-01 | 2006-08-01 | |
| US60/821,118 | 2006-08-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2008016995A2 WO2008016995A2 (fr) | 2008-02-07 |
| WO2008016995A3 true WO2008016995A3 (fr) | 2008-11-27 |
Family
ID=38997846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2007/075001 Ceased WO2008016995A2 (fr) | 2006-08-01 | 2007-08-01 | Procédés d'identification de modulateurs de la signalisation de l'insuline |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2008016995A2 (fr) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002085396A1 (fr) * | 2001-04-24 | 2002-10-31 | President And Fellows Of Harvard College | Inhibition de la kinase jun |
-
2007
- 2007-08-01 WO PCT/US2007/075001 patent/WO2008016995A2/fr not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002085396A1 (fr) * | 2001-04-24 | 2002-10-31 | President And Fellows Of Harvard College | Inhibition de la kinase jun |
Non-Patent Citations (4)
| Title |
|---|
| TANIGUCHI C.M. ET AL.: "Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN", PROC. NATL. ACAD. SCI. USA, vol. 103, no. 32, July 2006 (2006-07-01), pages 12093 - 12097 * |
| THIRONE A.C.P. ET AL.: "Opposite Effect of JAK2 on Insulin-Dependent Activation of Mitogen-Activated Protein Kinases and Akt in Muscle Cells", DIABETES, vol. 55, April 2006 (2006-04-01), pages 942 - 951 * |
| TUNCMAN G. ET AL.: "Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance", PROC. NATL. ACAD. SCI. USA, vol. 103, no. 28, July 2006 (2006-07-01), pages 10741 - 10746 * |
| USUI I. ET AL.: "Cdc-42 Is a Rho GTPase Family Member That Can Mediate Insulin Signaling to Glucose Transport in 3T3-L1 Adipocytes", J. BIOL. CHEM., vol. 278, no. 16, April 2003 (2003-04-01), pages 13765 - 13774 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008016995A2 (fr) | 2008-02-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 07840640 Country of ref document: EP Kind code of ref document: A2 |
|
| NENP | Non-entry into the national phase |
Ref country code: DE |
|
| NENP | Non-entry into the national phase |
Ref country code: RU |
|
| 122 | Ep: pct application non-entry in european phase |
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