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WO2008010199A3 - A nanofibre product - Google Patents

A nanofibre product Download PDF

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Publication number
WO2008010199A3
WO2008010199A3 PCT/IE2007/000070 IE2007000070W WO2008010199A3 WO 2008010199 A3 WO2008010199 A3 WO 2008010199A3 IE 2007000070 W IE2007000070 W IE 2007000070W WO 2008010199 A3 WO2008010199 A3 WO 2008010199A3
Authority
WO
WIPO (PCT)
Prior art keywords
nanofibre
product
oxidised polysaccharide
fibre
forming polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IE2007/000070
Other languages
French (fr)
Other versions
WO2008010199A2 (en
Inventor
Jana Ruzickova
Oldrich Jirsak
Jiri Briestensky
Ciaran O'reilly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NANOPEUTICS SRO
Nanopeutics S R O
Original Assignee
NANOPEUTICS SRO
Nanopeutics S R O
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NANOPEUTICS SRO, Nanopeutics S R O filed Critical NANOPEUTICS SRO
Publication of WO2008010199A2 publication Critical patent/WO2008010199A2/en
Publication of WO2008010199A3 publication Critical patent/WO2008010199A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/225Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28Polysaccharides or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0095Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C08B15/02Oxycellulose; Hydrocellulose; Cellulosehydrate, e.g. microcrystalline cellulose
    • C08B15/04Carboxycellulose, e.g. prepared by oxidation with nitrogen dioxide
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/02Cellulose; Modified cellulose
    • C08L1/04Oxycellulose; Hydrocellulose, e.g. microcrystalline cellulose
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01DMECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00Formation of filaments, threads, or the like
    • D01D5/0007Electro-spinning
    • D01D5/0015Electro-spinning characterised by the initial state of the material
    • D01D5/003Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01DMECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00Formation of filaments, threads, or the like
    • D01D5/0007Electro-spinning
    • D01D5/0061Electro-spinning characterised by the electro-spinning apparatus
    • D01D5/0076Electro-spinning characterised by the electro-spinning apparatus characterised by the collecting device, e.g. drum, wheel, endless belt, plate or grid
    • D01D5/0084Coating by electro-spinning, i.e. the electro-spun fibres are not removed from the collecting device but remain integral with it, e.g. coating of prostheses
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01FCHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F6/00Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
    • D01F6/44Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01FCHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F6/00Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
    • D01F6/88Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/12Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Textile Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Composite Materials (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A mesh comprises nanofibers of oxidised polysaccharide and a fibre-forming polymer. The oxidised polysaccharide is uniformly dispersed in the form of molecules and/or nanoparticles in a matrix of the fibre-forming polymer. The oxidised polysaccharide may be polyanhydroglucuronic acid or salts or intermolecular complexes thereof. The polymer may be PVA. The mesh may be used in wound dressings. The dressing may have multiple layers.
PCT/IE2007/000070 2006-07-18 2007-07-18 A nanofibre product Ceased WO2008010199A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83146606P 2006-07-18 2006-07-18
US60/831,466 2006-07-18

Publications (2)

Publication Number Publication Date
WO2008010199A2 WO2008010199A2 (en) 2008-01-24
WO2008010199A3 true WO2008010199A3 (en) 2008-03-20

Family

ID=38846976

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IE2007/000070 Ceased WO2008010199A2 (en) 2006-07-18 2007-07-18 A nanofibre product

Country Status (1)

Country Link
WO (1) WO2008010199A2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009074630A2 (en) * 2007-12-11 2009-06-18 Basf Se Process for producing nano- and mesofibres by electrospinning colloidal dispersions comprising at least one essentially water-insoluble polymer
EP2321123B1 (en) 2008-08-29 2018-08-08 Dow Silicones Corporation Metallized particles formed from a dispersion
TW201016909A (en) * 2008-08-29 2010-05-01 Dow Corning Article formed from electrospinning a dispersion
CZ302380B6 (en) * 2010-02-18 2011-04-20 Univerzita Tomáše Bati ve Zlíne Dry substance of hydrogel to cover wounds and process for preparing thereof
EP2600909B1 (en) * 2010-07-14 2014-11-19 Bard Access Systems, Inc. A dressing device for use with a cannula or a catheter
US20120094120A1 (en) 2010-10-18 2012-04-19 PurThread Technologies, Inc. Enhancing and preserving anti-microbial performance in fibers with pigments
FI126109B (en) * 2013-02-22 2016-06-30 Upm Kymmene Corp Nanofibrillar polysaccharide for use in inhibiting and controlling lace and scar formation
GB2511528A (en) 2013-03-06 2014-09-10 Speciality Fibres And Materials Ltd Absorbent materials
US9908987B2 (en) 2013-08-12 2018-03-06 PurThread Technologies, Inc. Antimicrobial and antifungal polymer fibers, fabrics, and methods of manufacture thereof
CN104153082B (en) * 2014-05-07 2016-08-03 新乡市凤泉化纤纺织有限公司 Aloe antibiotic yarn
WO2015183228A1 (en) * 2014-05-27 2015-12-03 Duymuş Ethem Nano fiber cover for wounds and ambustions with an additive containing natural antiseptic
US9878480B1 (en) 2014-06-24 2018-01-30 PurThread Technologies, Inc. Method for making polymer feedstock usable for generation of fiber having anti-microbial properties
CN104324407B (en) * 2014-09-26 2016-01-27 福州大学 A kind of preparation method of nano silver chloride/chitosan fiber antibacterial dressing
CZ2014674A3 (en) * 2014-09-30 2016-04-13 Nafigate Cosmetics, A.S. Application method of cosmetic preparation containing at least one active substance to skin and means for this cosmetic preparation application method l
CN104606710B (en) * 2015-02-03 2016-09-21 广东泰宝医疗科技股份有限公司 A kind of preparation method of high antibiotic property alginate dressing
CN106075558A (en) * 2016-07-18 2016-11-09 杭州语奥生物科技有限公司 Conservative restoration material and preparation method thereof after a kind of uterine cavity damage
CN107261198B (en) * 2017-06-28 2020-04-28 西北大学 A kind of preparation method of anti-seepage and anti-adhesion porous hemostatic gel dressing
CN107224605B (en) * 2017-06-28 2020-04-28 西北大学 Preparation method of high-permeability burn and scald dressing
CN107349464B (en) * 2017-06-28 2020-02-18 西北大学 A kind of preparation method of novel medical hemostatic gel dressing
CN107261199B (en) * 2017-06-28 2020-04-21 西北大学 A kind of preparation method of zeolite-containing hemostatic gel dressing
CN108048933B (en) * 2017-11-20 2021-02-26 河北吉藁化纤有限责任公司 A kind of copper-containing antibacterial viscose fiber and preparation method thereof
CN108434507B (en) * 2018-04-25 2021-05-11 南开大学 Ion-mediated dressing and preparation method and application thereof
CN114786737A (en) * 2019-10-04 2022-07-22 新加坡国立大学 Hemostatic device, hemostatic coating dispersion and hydrophobic surface
CN111068103B (en) * 2020-02-06 2020-12-18 牡丹江医学院 A kind of long-acting antibacterial gel dressing for surgical wound and preparation method thereof
KR102632849B1 (en) * 2021-11-17 2024-02-06 한국과학기술연구원 Nanofiber mat, nanofiber mat manufacturing apparatus and method

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2031661C1 (en) * 1993-07-16 1995-03-27 Научно-производственное предприятие "Экомедсервис" Agent for treatment of wounds and for rendering first medical aid
US6140257A (en) * 1996-04-12 2000-10-31 Bristol-Myers Squibb Company Composite fibres, wound dressings incorporating such fibres and a method for making same
US20030040487A1 (en) * 1998-07-21 2003-02-27 Ivan Santar Polymer complexes of glucuronoglucanes
US20030077231A1 (en) * 1997-01-30 2003-04-24 Alpenstock Holdings Limited Cellulose derivatives
US6753454B1 (en) * 1999-10-08 2004-06-22 The University Of Akron Electrospun fibers and an apparatus therefor
US20060013863A1 (en) * 2004-07-16 2006-01-19 Shalaby Shalaby W Hemostatic microfibrous constructs
US20060046590A1 (en) * 2004-08-27 2006-03-02 Stony Brook Technology And Applied Research Crosslinking of hyaluronan solutions and nanofiberous membranes made therefrom

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2031661C1 (en) * 1993-07-16 1995-03-27 Научно-производственное предприятие "Экомедсервис" Agent for treatment of wounds and for rendering first medical aid
US6140257A (en) * 1996-04-12 2000-10-31 Bristol-Myers Squibb Company Composite fibres, wound dressings incorporating such fibres and a method for making same
US20030077231A1 (en) * 1997-01-30 2003-04-24 Alpenstock Holdings Limited Cellulose derivatives
US20030040487A1 (en) * 1998-07-21 2003-02-27 Ivan Santar Polymer complexes of glucuronoglucanes
US6753454B1 (en) * 1999-10-08 2004-06-22 The University Of Akron Electrospun fibers and an apparatus therefor
US20060013863A1 (en) * 2004-07-16 2006-01-19 Shalaby Shalaby W Hemostatic microfibrous constructs
US20060046590A1 (en) * 2004-08-27 2006-03-02 Stony Brook Technology And Applied Research Crosslinking of hyaluronan solutions and nanofiberous membranes made therefrom

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
YOUNG SIC KANG ET AL: "MANUFACTURING THE CELLULOSE WEB BY USING ELECTRO-SPINNING AND IN-VITRO BEHAVIOUR OF OXIDIZED CELLULOSE WEB", HAN'GUG SEOMYU GONGHAG HOEJI-HAN'GUG SOMYU GONGHAGHOE - JOURNAL OF THE KOREAN FIBER SOCIETY, HAN'GUG SEOMYU GONGHAGHOE, SEOUL, KR, vol. 39, 2002, pages 14 - 20, XP008050645, ISSN: 1225-1089 *

Also Published As

Publication number Publication date
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