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WO2008004118A3 - Carthamus tinctoris plant extracts for treating osteoporosis and the extraction process thereof - Google Patents

Carthamus tinctoris plant extracts for treating osteoporosis and the extraction process thereof Download PDF

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Publication number
WO2008004118A3
WO2008004118A3 PCT/IB2007/002062 IB2007002062W WO2008004118A3 WO 2008004118 A3 WO2008004118 A3 WO 2008004118A3 IB 2007002062 W IB2007002062 W IB 2007002062W WO 2008004118 A3 WO2008004118 A3 WO 2008004118A3
Authority
WO
WIPO (PCT)
Prior art keywords
extracts
tinctoris
carthamus
plant
extraction process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2007/002062
Other languages
French (fr)
Other versions
WO2008004118A2 (en
Inventor
Villoo Morawala Patell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Avesthagen Ltd
Original Assignee
Avestha Gengraine Technologies Pvt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avestha Gengraine Technologies Pvt Ltd filed Critical Avestha Gengraine Technologies Pvt Ltd
Publication of WO2008004118A2 publication Critical patent/WO2008004118A2/en
Publication of WO2008004118A3 publication Critical patent/WO2008004118A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to compositions and methods for preventing, treating, or managing osteoporosis or conditions which are characterized by increased bone resorption, comprising administration of a prophylactically and therapeutically effective amount of Carthamus tinctoris plant or extracts thereof to a mammal in need of such therapy. Preferably the mammal is human and the compositions comprise of single extract or a combination of extracts thereof. The present invention further relates to extracts which are isolated from different parts of Carthamus tinctoris plant, the preparation of such extracts, the medicaments containing said extracts, and the use of these extracts and constituents for the preparation of a medicament. The present invention also relates to the process for preparing the extracts from various parts of Carthamus tinctoris plant.
PCT/IB2007/002062 2006-07-06 2007-07-09 Carthamus tinctoris plant extracts for treating osteoporosis and the extraction process thereof Ceased WO2008004118A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1176/CHE/2006 2006-07-06
IN1176CH2006 2006-07-06

Publications (2)

Publication Number Publication Date
WO2008004118A2 WO2008004118A2 (en) 2008-01-10
WO2008004118A3 true WO2008004118A3 (en) 2008-06-05

Family

ID=38894945

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/002062 Ceased WO2008004118A2 (en) 2006-07-06 2007-07-09 Carthamus tinctoris plant extracts for treating osteoporosis and the extraction process thereof

Country Status (1)

Country Link
WO (1) WO2008004118A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102552460A (en) * 2012-02-10 2012-07-11 河南省正骨研究院 Qi-benefiting and bone-growing Chinese medicinal preparation and preparation method thereof
CN103816198A (en) * 2012-11-16 2014-05-28 邢秋苓 Safflower extract and application thereof
CN103816197A (en) * 2012-11-16 2014-05-28 邢秋苓 Flos carthami extract capable of suppressing formation of osteoclast
CN105106363A (en) * 2015-09-29 2015-12-02 王磊 Traditional Chinese medicine for promoting healing of bone fracture
CN105079725A (en) * 2015-10-08 2015-11-25 王磊 Traditional Chinese medicine composition for treating bone fractures

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010016042A (en) * 2000-10-12 2001-03-05 김도완 Health functional snack containing safflower seed powder and process for preparation thereof
KR20010034963A (en) * 2000-04-04 2001-05-07 이원정 Novel Use of Polyphenol Compounds isolated from Safflower(Carthamus tinctorius L.) Seed
KR20030038870A (en) * 2001-11-06 2003-05-17 경상북도(승계청:경상북도농업기술원,관리청:경상북도 도지사) Preparation method of yangkang made with roasted safflower seed 45mesh powder
KR20030044973A (en) * 2003-05-16 2003-06-09 황규현 Food manufacturing process preventing from Neuralgia, Arthritis, Osteoporosis
EP1325681A1 (en) * 2001-12-11 2003-07-09 Société des Produits Nestlé S.A. Composition for promotion of bone growth and maintenance of bone health
WO2004052299A2 (en) * 2002-12-09 2004-06-24 Shaklee Corporation MODIFICATION OF CYCLOOXYGENASE AND LIPOXYGENASE ACTIVITY WITH ASTERIDAE EXTRACTS AND OPTIONALLy BOSWELLIC ACID
KR20050050291A (en) * 2003-11-25 2005-05-31 이광현 A herb remedy

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010034963A (en) * 2000-04-04 2001-05-07 이원정 Novel Use of Polyphenol Compounds isolated from Safflower(Carthamus tinctorius L.) Seed
KR20010016042A (en) * 2000-10-12 2001-03-05 김도완 Health functional snack containing safflower seed powder and process for preparation thereof
KR20030038870A (en) * 2001-11-06 2003-05-17 경상북도(승계청:경상북도농업기술원,관리청:경상북도 도지사) Preparation method of yangkang made with roasted safflower seed 45mesh powder
EP1325681A1 (en) * 2001-12-11 2003-07-09 Société des Produits Nestlé S.A. Composition for promotion of bone growth and maintenance of bone health
WO2004052299A2 (en) * 2002-12-09 2004-06-24 Shaklee Corporation MODIFICATION OF CYCLOOXYGENASE AND LIPOXYGENASE ACTIVITY WITH ASTERIDAE EXTRACTS AND OPTIONALLy BOSWELLIC ACID
KR20030044973A (en) * 2003-05-16 2003-06-09 황규현 Food manufacturing process preventing from Neuralgia, Arthritis, Osteoporosis
KR20050050291A (en) * 2003-11-25 2005-05-31 이광현 A herb remedy

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 200156, Derwent World Patents Index; AN 2001-510620, XP002475227 *
DATABASE WPI Week 200168, Derwent World Patents Index; AN 2001-600610, XP002475228 *
DATABASE WPI Week 200369, Derwent World Patents Index; AN 2003-728180, XP002475229 *
DATABASE WPI Week 200382, Derwent World Patents Index; AN 2003-892596, XP002475225 *
DATABASE WPI Week 200663, Derwent World Patents Index; AN 2006-609189, XP002475226 *
JANG HYE-OCK ET AL: "Effect of extracts from safflower seeds on osteoblastic differentiation and intracellular free calcium concentration in MCM-E1 cells", KOREAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, KOREAN PHYCOLIGICAL SOCIETY, SEOUL, KR, vol. 9, no. 1, February 2005 (2005-02-01), pages 55 - 62, XP009097696, ISSN: 1226-4512 *
KIM H J ET AL: "Bone-protecting effect of safflower seeds in ovariectomized rats", July 2002, CALCIFIED TISSUE INTERNATIONAL, VOL. 71, NR. 1, PAGE(S) 88-94, ISSN: 0171-967X, XP009097700 *

Also Published As

Publication number Publication date
WO2008004118A2 (en) 2008-01-10

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