[go: up one dir, main page]

WO2008001360A3 - Compositions and methods for treating and preventing gastro esophageal reflux disease - Google Patents

Compositions and methods for treating and preventing gastro esophageal reflux disease Download PDF

Info

Publication number
WO2008001360A3
WO2008001360A3 PCT/IL2007/000773 IL2007000773W WO2008001360A3 WO 2008001360 A3 WO2008001360 A3 WO 2008001360A3 IL 2007000773 W IL2007000773 W IL 2007000773W WO 2008001360 A3 WO2008001360 A3 WO 2008001360A3
Authority
WO
WIPO (PCT)
Prior art keywords
gerd
compositions
treating
reflux disease
esophageal reflux
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IL2007/000773
Other languages
French (fr)
Other versions
WO2008001360A2 (en
Inventor
Said Omar
Khalil Khaled
Uyad Khamaysi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lycored Ltd
Original Assignee
Lycored Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lycored Ltd filed Critical Lycored Ltd
Priority to EP07766804A priority Critical patent/EP2043669A4/en
Priority to CA002656220A priority patent/CA2656220A1/en
Publication of WO2008001360A2 publication Critical patent/WO2008001360A2/en
Anticipated expiration legal-status Critical
Publication of WO2008001360A3 publication Critical patent/WO2008001360A3/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to methods and compositions effective in treating, preventing, reducing the severity of, or relieving the symptoms of, Gastro Esophageal Reflux Disease (GERD). The compositions comprise, as an active ingredient, an extract from the plant genus Conyza Less, preferably from the species Conyza bonariensis (L) Cronq. The composition comprises only natural ingredients and has been demonstrated to be safe for use, while still providing a beneficial therapeutic effect. The composition can also be administered in combination with traditional anti-GERD medicines, either over-the-counter or prescription medicines such as antacids, H2-receptor agonists, proton pump inhibitors, promotility agents and Sucralfate. The compositions are particularly effective in treating and preventing GERD, the symptoms or GERD and conditions associated with GERD, including heartburn, regurgitation, esophagitis, Non-Erosive Esophageal Reflux Disease (NERD), Barrett's Esophagus, and any combination thereof.
PCT/IL2007/000773 2006-06-28 2007-06-26 Compositions and methods for treating and preventing gastro esophageal reflux disease Ceased WO2008001360A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07766804A EP2043669A4 (en) 2006-06-28 2007-06-26 COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF PATHOLOGICAL GASTRO-SOPHAGEAL REFLUX
CA002656220A CA2656220A1 (en) 2006-06-28 2007-06-26 Compositions and methods for treating and preventing gastro esophageal reflux disease

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL176608A IL176608A0 (en) 2006-06-28 2006-06-28 Compositions and methods for treating and preventing gastro esophageal reflux disease
IL176608 2006-06-28

Publications (2)

Publication Number Publication Date
WO2008001360A2 WO2008001360A2 (en) 2008-01-03
WO2008001360A3 true WO2008001360A3 (en) 2009-04-30

Family

ID=38846091

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2007/000773 Ceased WO2008001360A2 (en) 2006-06-28 2007-06-26 Compositions and methods for treating and preventing gastro esophageal reflux disease

Country Status (4)

Country Link
EP (1) EP2043669A4 (en)
CA (1) CA2656220A1 (en)
IL (1) IL176608A0 (en)
WO (1) WO2008001360A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108578654A (en) * 2018-05-22 2018-09-28 中国中医科学院西苑医院 A kind of Chinese medicine composition and preparation method thereof for treating Non-erosive reflux disease

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201700090582A1 (en) * 2017-08-04 2019-02-04 Neilos S R L Composition for use in the prevention and / or treatment of gastric or gastroesophageal disorders.
CN110353271B (en) * 2019-06-13 2022-07-22 陕西科技大学 Special medical food thickening component for inhibiting esophagus reflux and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101032333A (en) * 2007-04-11 2007-09-12 朱西杰 Herbal meal of gastrointestinal sustained release particle for protecting gastrointestinal mucosa

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1340356A (en) * 2000-08-28 2002-03-20 黄兴 Chinese medicine for treating enterogastric disease
FR2843125B1 (en) * 2002-08-02 2012-11-16 Coletica ACTIVE PRINCIPLES STIMULATING HUMAN BETA-DEFENSIVE TYPE 2 AND / OR TYPE 3, AND COSMETIC OR PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101032333A (en) * 2007-04-11 2007-09-12 朱西杰 Herbal meal of gastrointestinal sustained release particle for protecting gastrointestinal mucosa

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KONG, L. D. ET AL.: "Glycosides and Xanthine Oxidase Inhibitors from Conyza bonariensis", vol. 58, no. 4, October 2001 (2001-10-01), pages 645 - 651, XP004306136 *
SOUZA, M.C. ET AL.: "Evaluation of Anti-Inflammatory Activity of Essential Oils from two Asteraceae Species.", PHARMAZIE., vol. 58, no. 8, August 2003 (2003-08-01), pages 582 - 586, XP001537158 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108578654A (en) * 2018-05-22 2018-09-28 中国中医科学院西苑医院 A kind of Chinese medicine composition and preparation method thereof for treating Non-erosive reflux disease
CN108578654B (en) * 2018-05-22 2021-11-12 中国中医科学院西苑医院 Traditional Chinese medicine composition for treating non-erosive reflux disease and preparation method thereof

Also Published As

Publication number Publication date
EP2043669A4 (en) 2011-06-22
WO2008001360A2 (en) 2008-01-03
EP2043669A2 (en) 2009-04-08
IL176608A0 (en) 2006-10-31
CA2656220A1 (en) 2008-01-03

Similar Documents

Publication Publication Date Title
Furrer et al. Ocular tolerance of preservatives and alternatives
Bandyopadhyay et al. Reactive oxygen species-induced gastric ulceration: protection by melatonin
WO2009158625A3 (en) Compositions and methods for treating or preventing gastrointestinal disorders and gerd-related respiratory disorders
NO20073289L (en) Controlled release nanoparticle compositions comprising cephalosporin
WO2008089268A3 (en) Methods and compositions for treating conditions associated with infection and/or inflammation
NZ701559A (en) Compositions comprising povidone-iodine
NO20083968L (en) Use of A2B adenosine receptor antagonists to prevent and treat hepatic disease
MA29795B1 (en) INHIBITORS OF DIPEPTIDYL PEPTIDASE FOR THE TREATMENT OF DIABETES
Chakrabarti et al. Screening of nine herbal plants for in vitro a-amylase inhibition
WO2008002514A3 (en) Combination cough treatment compounds and method of treating common coughs
WO2008079993A3 (en) Combinations of nitric oxide and sulfide and methods of use and manufacture thereof
WO2008014256A3 (en) Composition including superoxide dismutase and prickly-pear cactus for minimizing and preventing hangovers
EP2478895A3 (en) Compositions for treating esophageal disorders
WO2006068768A3 (en) Methods and compositions for treating conditions
TW200744617A (en) Agent increasing the production of thioredoxin
WO2005067890A3 (en) Controlled release cgrp delivery composition for cardiovascular and renal indications
WO2008001360A3 (en) Compositions and methods for treating and preventing gastro esophageal reflux disease
WO2002017898A3 (en) Compositions and methods for inducing vasorelaxation
WO2007064968A3 (en) Stable pharmaceutical compositions of 5,10 methylenetetrahydrofolate
Nabavizadeh et al. Gastroprotective effects of Stachys Lavandulifolia extract on experimental gastric ulcer
WO2006014788A8 (en) Methods of use of herbal compositions
WO2007041614A3 (en) Long acting vegf inhibitors and methods of use
WO2010079910A3 (en) Eyesight-protecting composition containing functional components having preventive and therapeutic efficacy in diabetes or diabetes complications
WO2009019307A3 (en) Oral calcitonin compositions and applications thereof
WO2005102309A3 (en) In vivo release of endogenous anti-microbial mediators by leukotriene b4 (ltb4) administration

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07766804

Country of ref document: EP

Kind code of ref document: A2

ENP Entry into the national phase

Ref document number: 2656220

Country of ref document: CA

NENP Non-entry into the national phase

Ref country code: DE

NENP Non-entry into the national phase

Ref country code: RU

WWE Wipo information: entry into national phase

Ref document number: 2007766804

Country of ref document: EP