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WO2006118990A3 - Procede et dispositif destines a la perfusion d'organe - Google Patents

Procede et dispositif destines a la perfusion d'organe Download PDF

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Publication number
WO2006118990A3
WO2006118990A3 PCT/US2006/016163 US2006016163W WO2006118990A3 WO 2006118990 A3 WO2006118990 A3 WO 2006118990A3 US 2006016163 W US2006016163 W US 2006016163W WO 2006118990 A3 WO2006118990 A3 WO 2006118990A3
Authority
WO
WIPO (PCT)
Prior art keywords
organ
fluid
perfusion
perfusion fluid
oxygenator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/016163
Other languages
English (en)
Other versions
WO2006118990A2 (fr
Inventor
Marlin L Alford
Robert M Dowben
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TRANSPLAN Inc
Original Assignee
TRANSPLAN Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TRANSPLAN Inc filed Critical TRANSPLAN Inc
Priority to EP06751728A priority Critical patent/EP1879997A2/fr
Publication of WO2006118990A2 publication Critical patent/WO2006118990A2/fr
Publication of WO2006118990A3 publication Critical patent/WO2006118990A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142—Apparatus
    • A01N1/143—Apparatus for organ perfusion
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention concerne un dispositif de perfusion d'organe portatif comportant une chambre à organes destinée à supporter un organe immergé dans un fluide de perfusion. Une pompe fait circuler le fluide de perfusion autour d'un circuit contenant une pompe, un échangeur thermique destiné à refroidir le fluide de perfusion, un oxygénateur destiné à oxygéner le fluide de perfusion, et un chargeur de pression destiné à assurer une alimentation constante de la tête vers le système vasculaire de l'organe. Un canal de dérivation forme une connexion fluidique à partir du flux en amont de l'oxygénateur vers la chambre à organes permettant à l'excès de fluide de contourner l'organe. Le dispositif comprend également une source d'oxygène, des capteurs, une source de puissance et une unité de commande destinée à recevoir des informations provenant des capteurs et à fournir des instructions de commande aux éléments de commande.
PCT/US2006/016163 2005-04-29 2006-04-28 Procede et dispositif destines a la perfusion d'organe Ceased WO2006118990A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06751728A EP1879997A2 (fr) 2005-04-29 2006-04-28 Procede et dispositif destines a la perfusion d'organe

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67632905P 2005-04-29 2005-04-29
US60/676,329 2005-04-29

Publications (2)

Publication Number Publication Date
WO2006118990A2 WO2006118990A2 (fr) 2006-11-09
WO2006118990A3 true WO2006118990A3 (fr) 2007-01-25

Family

ID=37308518

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/016163 Ceased WO2006118990A2 (fr) 2005-04-29 2006-04-28 Procede et dispositif destines a la perfusion d'organe

Country Status (2)

Country Link
EP (1) EP1879997A2 (fr)
WO (1) WO2006118990A2 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5705324B2 (ja) * 2010-09-01 2015-04-22 パフュージョン・フルイド・テクノロジーズ・インコーポレイテッドＰｅｒｆｕｓｉｏｎ Ｆｌｕｉｄ Ｔｅｃｈｎｏｌｏｇｉｅｓ， Ｉｎｃ． 灌流組成物
US9119392B2 (en) * 2010-11-09 2015-09-01 Biomedinnovations, Llc Articulating organ support
CA2847368C (fr) 2011-09-02 2017-10-31 Organ Assist B.V. Appareil, systeme et methode pour le conditionnement et la conservation d'un organe d'un donneur
CN104039137B (zh) 2011-11-10 2017-03-08 奥加诺克斯有限责任公司 器官灌注系统
GB2510080B (en) 2011-11-10 2017-09-27 Organox Ltd Organ perfusion systems
GB201119420D0 (en) 2011-11-10 2011-12-21 Organox Ltd Oxygen supply for organ perfusion systems
US20140370490A1 (en) * 2013-06-12 2014-12-18 Medtronic, Inc. Heart-lung preparation and method of use
SE1330158A1 (sv) * 2013-12-30 2015-07-01 Vivoline Medical Ab Insats för en transportanordning för organ
WO2017134192A1 (fr) * 2016-02-04 2017-08-10 Xvivo Perfusion Ab Simulateur pulmonaire ex vivo
CN106754355A (zh) * 2016-11-23 2017-05-31 厦门大学 一种器官体外培养系统
CN110122474B (zh) * 2019-04-26 2021-08-10 浙江机电职业技术学院 一种基于非接触传感控制灌注技术的人体断肢保护箱
GB2587350B (en) * 2019-09-23 2021-12-15 Royal Papworth Hospital Nhs Found Trust Organ perfusion system and method
IL323003A (en) * 2020-02-20 2025-10-01 Deka Products Lp System and method for maintaining and transferring a body part
CN111657268A (zh) * 2020-03-31 2020-09-15 同济大学 一种小动物心脏成像灌流软管系统
WO2022137164A1 (fr) 2020-12-22 2022-06-30 Polbionica Sp. Z O.O. Système de stockage ou de culture d'un organe ou d'un modèle de tissu et utilisations de celui-ci
CN114342918B (zh) * 2021-02-08 2023-01-17 苏州心擎医疗技术有限公司 温血器官转运平台及排气方法

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002965A (en) * 1989-05-09 1991-03-26 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Use of ginkgolides to prevent reperfusion injury in organ transplantation
DE4201259A1 (de) * 1992-01-18 1993-07-22 Sachs Elektronik Kg Hugo Vorrichtung zur perfusion eines isolierten herzens
US5405742A (en) * 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
US5693462A (en) * 1994-12-12 1997-12-02 Charlotte-Mecklenburg Hospital Authority Organ transplant solutions and method for transplanting an organ
US5702881A (en) * 1993-03-16 1997-12-30 Alliance Pharmaceutical Corp. Method and solution for organ preservation comprising retinal-derived growth factor, cyclodextrin, mucopolysaccharide and fluorocarbon
US5965433A (en) * 1996-05-29 1999-10-12 Trans D.A.T.A. Service, Inc. Portable perfusion/oxygenation module having mechanically linked dual pumps and mechanically actuated flow control for pulsatile cycling of oxygenated perfusate
US6046046A (en) * 1997-09-23 2000-04-04 Hassanein; Waleed H. Compositions, methods and devices for maintaining an organ
US6582375B2 (en) * 2001-10-11 2003-06-24 University Of Cincinnati System for study of global uni-or bi-ventricular function of an explanted, reperfused heart
US6673594B1 (en) * 1998-09-29 2004-01-06 Organ Recovery Systems Apparatus and method for maintaining and/or restoring viability of organs

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002965A (en) * 1989-05-09 1991-03-26 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Use of ginkgolides to prevent reperfusion injury in organ transplantation
DE4201259A1 (de) * 1992-01-18 1993-07-22 Sachs Elektronik Kg Hugo Vorrichtung zur perfusion eines isolierten herzens
US5702881A (en) * 1993-03-16 1997-12-30 Alliance Pharmaceutical Corp. Method and solution for organ preservation comprising retinal-derived growth factor, cyclodextrin, mucopolysaccharide and fluorocarbon
US5405742A (en) * 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
US5693462A (en) * 1994-12-12 1997-12-02 Charlotte-Mecklenburg Hospital Authority Organ transplant solutions and method for transplanting an organ
US5965433A (en) * 1996-05-29 1999-10-12 Trans D.A.T.A. Service, Inc. Portable perfusion/oxygenation module having mechanically linked dual pumps and mechanically actuated flow control for pulsatile cycling of oxygenated perfusate
US6046046A (en) * 1997-09-23 2000-04-04 Hassanein; Waleed H. Compositions, methods and devices for maintaining an organ
US6673594B1 (en) * 1998-09-29 2004-01-06 Organ Recovery Systems Apparatus and method for maintaining and/or restoring viability of organs
US6582375B2 (en) * 2001-10-11 2003-06-24 University Of Cincinnati System for study of global uni-or bi-ventricular function of an explanted, reperfused heart

Also Published As

Publication number Publication date
WO2006118990A2 (fr) 2006-11-09
EP1879997A2 (fr) 2008-01-23

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