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WO2006118990A3 - Method and device for organ perfusion - Google Patents

Method and device for organ perfusion Download PDF

Info

Publication number
WO2006118990A3
WO2006118990A3 PCT/US2006/016163 US2006016163W WO2006118990A3 WO 2006118990 A3 WO2006118990 A3 WO 2006118990A3 US 2006016163 W US2006016163 W US 2006016163W WO 2006118990 A3 WO2006118990 A3 WO 2006118990A3
Authority
WO
WIPO (PCT)
Prior art keywords
organ
fluid
perfusion
perfusion fluid
oxygenator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/016163
Other languages
French (fr)
Other versions
WO2006118990A2 (en
Inventor
Marlin L Alford
Robert M Dowben
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TRANSPLAN Inc
Original Assignee
TRANSPLAN Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TRANSPLAN Inc filed Critical TRANSPLAN Inc
Priority to EP06751728A priority Critical patent/EP1879997A2/en
Publication of WO2006118990A2 publication Critical patent/WO2006118990A2/en
Publication of WO2006118990A3 publication Critical patent/WO2006118990A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142—Apparatus
    • A01N1/143—Apparatus for organ perfusion
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

A portable organ perfusion device has an organ chamber for supporting an organ immersed in a perfusion fluid. A pump circulates the perfusion fluid around a circuit containing a pump, a heat exchanger for cooling the perfusion fluid, an oxygenator for oxygenation of the perfusion fluid, and a pressure head device for ensuring a constant head supply to the vasculature of the organ. A bypass channel forms a fluid connection from upstream of the oxygenator to the organ chamber allowing excess fluid to bypass the organ. The device also includes an oxygen source, sensors, a power source and a control unit for receiving information from the sensors and providing control instructions to control elements.
PCT/US2006/016163 2005-04-29 2006-04-28 Method and device for organ perfusion Ceased WO2006118990A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06751728A EP1879997A2 (en) 2005-04-29 2006-04-28 Method and device for organ perfusion

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67632905P 2005-04-29 2005-04-29
US60/676,329 2005-04-29

Publications (2)

Publication Number Publication Date
WO2006118990A2 WO2006118990A2 (en) 2006-11-09
WO2006118990A3 true WO2006118990A3 (en) 2007-01-25

Family

ID=37308518

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/016163 Ceased WO2006118990A2 (en) 2005-04-29 2006-04-28 Method and device for organ perfusion

Country Status (2)

Country Link
EP (1) EP1879997A2 (en)
WO (1) WO2006118990A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5705324B2 (en) * 2010-09-01 2015-04-22 パフュージョン・フルイド・テクノロジーズ・インコーポレイテッドＰｅｒｆｕｓｉｏｎ Ｆｌｕｉｄ Ｔｅｃｈｎｏｌｏｇｉｅｓ， Ｉｎｃ． Perfusion composition
US9119392B2 (en) * 2010-11-09 2015-09-01 Biomedinnovations, Llc Articulating organ support
CA2847368C (en) 2011-09-02 2017-10-31 Organ Assist B.V. Apparatus, system and method for conditioning and preserving an organ from a donor
CN104039137B (en) 2011-11-10 2017-03-08 奥加诺克斯有限责任公司 Organ perfusion system
GB2510080B (en) 2011-11-10 2017-09-27 Organox Ltd Organ perfusion systems
GB201119420D0 (en) 2011-11-10 2011-12-21 Organox Ltd Oxygen supply for organ perfusion systems
US20140370490A1 (en) * 2013-06-12 2014-12-18 Medtronic, Inc. Heart-lung preparation and method of use
SE1330158A1 (en) * 2013-12-30 2015-07-01 Vivoline Medical Ab Insert for an organ transport device
WO2017134192A1 (en) * 2016-02-04 2017-08-10 Xvivo Perfusion Ab Ex vivo lung simulator
CN106754355A (en) * 2016-11-23 2017-05-31 厦门大学 A kind of organ vitro culture system
CN110122474B (en) * 2019-04-26 2021-08-10 浙江机电职业技术学院 Human body broken limb protection box based on non-contact sensing control perfusion technology
GB2587350B (en) * 2019-09-23 2021-12-15 Royal Papworth Hospital Nhs Found Trust Organ perfusion system and method
IL323003A (en) * 2020-02-20 2025-10-01 Deka Products Lp System and method for organ maintenance and transport
CN111657268A (en) * 2020-03-31 2020-09-15 同济大学 Small animal heart imaging perfusion hose system
WO2022137164A1 (en) 2020-12-22 2022-06-30 Polbionica Sp. Z O.O. A system for storing or cultivating of an organ or tissue model and uses thereof
CN114342918B (en) * 2021-02-08 2023-01-17 苏州心擎医疗技术有限公司 Warm-blooded organ transfer platform and exhaust method

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002965A (en) * 1989-05-09 1991-03-26 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Use of ginkgolides to prevent reperfusion injury in organ transplantation
DE4201259A1 (en) * 1992-01-18 1993-07-22 Sachs Elektronik Kg Hugo DEVICE FOR PERFUSING AN INSULATED HEART
US5405742A (en) * 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
US5693462A (en) * 1994-12-12 1997-12-02 Charlotte-Mecklenburg Hospital Authority Organ transplant solutions and method for transplanting an organ
US5702881A (en) * 1993-03-16 1997-12-30 Alliance Pharmaceutical Corp. Method and solution for organ preservation comprising retinal-derived growth factor, cyclodextrin, mucopolysaccharide and fluorocarbon
US5965433A (en) * 1996-05-29 1999-10-12 Trans D.A.T.A. Service, Inc. Portable perfusion/oxygenation module having mechanically linked dual pumps and mechanically actuated flow control for pulsatile cycling of oxygenated perfusate
US6046046A (en) * 1997-09-23 2000-04-04 Hassanein; Waleed H. Compositions, methods and devices for maintaining an organ
US6582375B2 (en) * 2001-10-11 2003-06-24 University Of Cincinnati System for study of global uni-or bi-ventricular function of an explanted, reperfused heart
US6673594B1 (en) * 1998-09-29 2004-01-06 Organ Recovery Systems Apparatus and method for maintaining and/or restoring viability of organs

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002965A (en) * 1989-05-09 1991-03-26 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Use of ginkgolides to prevent reperfusion injury in organ transplantation
DE4201259A1 (en) * 1992-01-18 1993-07-22 Sachs Elektronik Kg Hugo DEVICE FOR PERFUSING AN INSULATED HEART
US5702881A (en) * 1993-03-16 1997-12-30 Alliance Pharmaceutical Corp. Method and solution for organ preservation comprising retinal-derived growth factor, cyclodextrin, mucopolysaccharide and fluorocarbon
US5405742A (en) * 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
US5693462A (en) * 1994-12-12 1997-12-02 Charlotte-Mecklenburg Hospital Authority Organ transplant solutions and method for transplanting an organ
US5965433A (en) * 1996-05-29 1999-10-12 Trans D.A.T.A. Service, Inc. Portable perfusion/oxygenation module having mechanically linked dual pumps and mechanically actuated flow control for pulsatile cycling of oxygenated perfusate
US6046046A (en) * 1997-09-23 2000-04-04 Hassanein; Waleed H. Compositions, methods and devices for maintaining an organ
US6673594B1 (en) * 1998-09-29 2004-01-06 Organ Recovery Systems Apparatus and method for maintaining and/or restoring viability of organs
US6582375B2 (en) * 2001-10-11 2003-06-24 University Of Cincinnati System for study of global uni-or bi-ventricular function of an explanted, reperfused heart

Also Published As

Publication number Publication date
WO2006118990A2 (en) 2006-11-09
EP1879997A2 (en) 2008-01-23

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