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WO2006000776A3 - Implantable biocompatible devices and methods for their manufacture - Google Patents

Implantable biocompatible devices and methods for their manufacture Download PDF

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Publication number
WO2006000776A3
WO2006000776A3 PCT/GB2005/002476 GB2005002476W WO2006000776A3 WO 2006000776 A3 WO2006000776 A3 WO 2006000776A3 GB 2005002476 W GB2005002476 W GB 2005002476W WO 2006000776 A3 WO2006000776 A3 WO 2006000776A3
Authority
WO
WIPO (PCT)
Prior art keywords
valve
layer
layers
leaflets
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2005/002476
Other languages
French (fr)
Other versions
WO2006000776A2 (en
Inventor
David John Wheatley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Glasgow
Original Assignee
University of Glasgow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Glasgow filed Critical University of Glasgow
Publication of WO2006000776A2 publication Critical patent/WO2006000776A2/en
Publication of WO2006000776A3 publication Critical patent/WO2006000776A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Implantable biocompatible devices such as synthetic prosthetic heart valves are disclosed. The trileaflet aortic heart valve design has three valve leaflets supported on a frame. The leaflets are made up of a number of layers, each layer being formed by drying a layer of polymer solution in a preferred shape, different to the preferred shape of other layers. This allows the valve to have different configurations in which one or more of the layers are in a minimal stress configuration. This can provide the leaflets with improved flexibility. Furthermore, a partially open valve configuration is described, providing the valve with upstream bulge portions in the sub-commissural regions of the valve, allowing improved opening and washout of the valve. Still further, a method of manufacturing the valve is disclosed, in which a layer of the valve is distended in order to apply a layer of porous material by electrostatic spinning.
PCT/GB2005/002476 2004-06-23 2005-06-22 Implantable biocompatible devices and methods for their manufacture Ceased WO2006000776A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0414099.2 2004-06-23
GB0414099A GB0414099D0 (en) 2004-06-23 2004-06-23 Biocompatible layered structures and methods for their manufacture

Publications (2)

Publication Number Publication Date
WO2006000776A2 WO2006000776A2 (en) 2006-01-05
WO2006000776A3 true WO2006000776A3 (en) 2006-04-27

Family

ID=32800058

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/GB2005/002455 Ceased WO2006000763A2 (en) 2004-06-23 2005-06-22 Biocompatible layered structures and methods for their manufacture
PCT/GB2005/002476 Ceased WO2006000776A2 (en) 2004-06-23 2005-06-22 Implantable biocompatible devices and methods for their manufacture

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/GB2005/002455 Ceased WO2006000763A2 (en) 2004-06-23 2005-06-22 Biocompatible layered structures and methods for their manufacture

Country Status (2)

Country Link
GB (1) GB0414099D0 (en)
WO (2) WO2006000763A2 (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7244242B2 (en) 2002-12-30 2007-07-17 Boston Scientific Scimed, Inc. Valve treatment catheter and methods
US7267686B2 (en) 1999-10-21 2007-09-11 Boston Scientific Scimed, Inc Implantable prosthetic valve
US7416557B2 (en) 2002-10-24 2008-08-26 Boston Scientific Scimed, Inc. Venous valve apparatus and method
US7566343B2 (en) 2004-09-02 2009-07-28 Boston Scientific Scimed, Inc. Cardiac valve, system, and method
US7569071B2 (en) 2005-09-21 2009-08-04 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
US8721717B2 (en) 2003-12-19 2014-05-13 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US9301843B2 (en) 2003-12-19 2016-04-05 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US9370419B2 (en) 2005-02-23 2016-06-21 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US9421083B2 (en) 2007-02-05 2016-08-23 Boston Scientific Scimed Inc. Percutaneous valve, system and method

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US20060173490A1 (en) 2005-02-01 2006-08-03 Boston Scientific Scimed, Inc. Filter system and method
US7722666B2 (en) 2005-04-15 2010-05-25 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US8012198B2 (en) 2005-06-10 2011-09-06 Boston Scientific Scimed, Inc. Venous valve, system, and method
US8133270B2 (en) 2007-01-08 2012-03-13 California Institute Of Technology In-situ formation of a valve
US8278406B2 (en) 2007-04-27 2012-10-02 Wisconsin Alumni Research Foundation Bioactive and biocompatible polyurethane-buthanediol-glycosaminoglycan salt copolymers
US7892276B2 (en) 2007-12-21 2011-02-22 Boston Scientific Scimed, Inc. Valve with delayed leaflet deployment
EP2340055B1 (en) 2008-08-19 2017-01-25 DSM IP Assets B.V. Implantable valve prosthesis and method for manufacturing such a valve
US8961599B2 (en) 2011-04-01 2015-02-24 W. L. Gore & Associates, Inc. Durable high strength polymer composite suitable for implant and articles produced therefrom
US9554900B2 (en) 2011-04-01 2017-01-31 W. L. Gore & Associates, Inc. Durable high strength polymer composites suitable for implant and articles produced therefrom
US9801712B2 (en) 2011-04-01 2017-10-31 W. L. Gore & Associates, Inc. Coherent single layer high strength synthetic polymer composites for prosthetic valves
US9744033B2 (en) 2011-04-01 2017-08-29 W.L. Gore & Associates, Inc. Elastomeric leaflet for prosthetic heart valves
US20130197631A1 (en) 2011-04-01 2013-08-01 W. L. Gore & Associates, Inc. Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom
US8945212B2 (en) * 2011-04-01 2015-02-03 W. L. Gore & Associates, Inc. Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom
US9668859B2 (en) 2011-08-05 2017-06-06 California Institute Of Technology Percutaneous heart valve delivery systems
US9554806B2 (en) 2011-09-16 2017-01-31 W. L. Gore & Associates, Inc. Occlusive devices
EP2866847B1 (en) 2012-07-02 2018-08-22 Boston Scientific Scimed, Inc. Prosthetic heart valve formation
EP2967945B1 (en) 2013-03-15 2020-10-28 California Institute of Technology Handle mechanism and functionality for repositioning and retrieval of transcatheter heart valves
US11911258B2 (en) 2013-06-26 2024-02-27 W. L. Gore & Associates, Inc. Space filling devices
WO2015053934A1 (en) * 2013-10-10 2015-04-16 Medtronic, Inc. Implantable medical devices including a polyether-polyurethane substrate with improved biostability, and methods
US9545042B2 (en) 2014-03-14 2017-01-10 Ppg Industries Ohio, Inc. P-static charge drain layer including carbon nanotubes
US10442549B2 (en) 2015-04-02 2019-10-15 Ppg Industries Ohio, Inc. Liner-type, antistatic topcoat system for aircraft canopies and windshields
US10299915B2 (en) 2015-04-09 2019-05-28 Boston Scientific Scimed, Inc. Synthetic heart valves composed of zwitterionic polymers
US10314696B2 (en) 2015-04-09 2019-06-11 Boston Scientific Scimed, Inc. Prosthetic heart valves having fiber reinforced leaflets
US10426609B2 (en) 2015-04-09 2019-10-01 Boston Scientific Scimed, Inc. Fiber reinforced prosthetic heart valve having undulating fibers
CN107847232B (en) 2015-05-14 2022-05-10 W.L.戈尔及同仁股份有限公司 Device for occluding the atrial appendage
US10716671B2 (en) 2015-07-02 2020-07-21 Boston Scientific Scimed, Inc. Prosthetic heart valve composed of composite fibers
US10413403B2 (en) 2015-07-14 2019-09-17 Boston Scientific Scimed, Inc. Prosthetic heart valve including self-reinforced composite leaflets
US10195023B2 (en) 2015-09-15 2019-02-05 Boston Scientific Scimed, Inc. Prosthetic heart valves including pre-stressed fibers
EP3429647A1 (en) 2016-03-17 2019-01-23 Centro Cardiologico Monzino Polymers and uses thereof in manufacturing of 'living' heart valves
EP3457989B1 (en) 2016-05-19 2021-09-29 Boston Scientific Scimed, Inc. Prosthetic valves, valve leaflets and related methods
CN106726008B (en) * 2017-01-04 2019-01-22 周诚 A kind of valve and preparation method thereof
US10925998B2 (en) 2017-04-25 2021-02-23 Boston Scientific Scimed, Inc. Method of manufacturing a biocompatible composite material
US11173023B2 (en) 2017-10-16 2021-11-16 W. L. Gore & Associates, Inc. Medical devices and anchors therefor
CN108014371A (en) * 2017-12-29 2018-05-11 上海纽脉医疗科技有限公司 A kind of renewable cardiac valves and its preparation facilities, method
US12245935B2 (en) 2019-11-26 2025-03-11 Boston Scientific Limited Composite web-polymer heart valve
EP4081270A4 (en) * 2019-12-26 2024-01-17 The Trustees Of Columbia University In The City Of New York BIOMIMETIC POLYMERIC COMPOSITE FOR HEART VALVE REPAIR
EP4572684A1 (en) 2022-08-16 2025-06-25 Boston Scientific Scimed, Inc. Medical device for occluding a left atrial appendage
CN120302944A (en) * 2022-12-23 2025-07-11 杭州启明医疗器械股份有限公司 Implantable material, artificial prosthesis, artificial heart valve, leaflet preform and preparation method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4218782A (en) * 1977-05-25 1980-08-26 Biocoating Anpartsselskab Heart valve prosthesis and method for the production thereof
US20030109922A1 (en) * 2001-12-12 2003-06-12 Peterson Paul C. Polymer heart valve with perforated stent and sewing cuff

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US4253463A (en) * 1979-10-19 1981-03-03 Kim Il B Method of reducing infection utilizing an intravascular device having antiseptic metal portion
CH641063A5 (en) * 1979-12-06 1984-02-15 Balzers Hochvakuum METHOD FOR COATING A SURFACE PART OF AN ELASTIC BODY WITH A CONTINUOUS LAYER.
DE3239032C2 (en) * 1982-10-21 1986-09-11 Siemens AG, 1000 Berlin und 8000 München Catheter tube
US4888009A (en) * 1985-04-05 1989-12-19 Abiomed, Inc. Prosthetic heart valve
EP0484680A1 (en) * 1990-10-09 1992-05-13 The Furukawa Electric Co., Ltd. Method of producing catheter and catheter thus obtained
US5468562A (en) * 1991-03-01 1995-11-21 Spire Corporation Metallized polymeric implant with ion embedded coating
US7658727B1 (en) * 1998-04-20 2010-02-09 Medtronic, Inc Implantable medical device with enhanced biocompatibility and biostability
AU3724900A (en) * 1999-03-05 2000-09-21 Louis R. Matson Surface-modified bioactive surgical implants suppressing tissue growth
US6475235B1 (en) * 1999-11-16 2002-11-05 Iowa-India Investments Company, Limited Encapsulated stent preform
DE10050305A1 (en) * 2000-10-09 2002-04-11 Adiam Life Science Ag Production of thin membranes, especially flaps for heart valves, comprises applying drops of polymer solution or viscous, multicomponent polymerizable system in line or over surface of a base or support and then drying
EP1539262A1 (en) * 2002-07-29 2005-06-15 Potencia Medical AG Durable implant
DE10256120B4 (en) * 2002-11-29 2005-04-14 Holger Heuser Medical instrument and method for applying a mark on such an instrument
US20040111144A1 (en) * 2002-12-06 2004-06-10 Lawin Laurie R. Barriers for polymeric coatings

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4218782A (en) * 1977-05-25 1980-08-26 Biocoating Anpartsselskab Heart valve prosthesis and method for the production thereof
US20030109922A1 (en) * 2001-12-12 2003-06-12 Peterson Paul C. Polymer heart valve with perforated stent and sewing cuff

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7267686B2 (en) 1999-10-21 2007-09-11 Boston Scientific Scimed, Inc Implantable prosthetic valve
US7416557B2 (en) 2002-10-24 2008-08-26 Boston Scientific Scimed, Inc. Venous valve apparatus and method
US7244242B2 (en) 2002-12-30 2007-07-17 Boston Scientific Scimed, Inc. Valve treatment catheter and methods
US8721717B2 (en) 2003-12-19 2014-05-13 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US9301843B2 (en) 2003-12-19 2016-04-05 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7566343B2 (en) 2004-09-02 2009-07-28 Boston Scientific Scimed, Inc. Cardiac valve, system, and method
US8932349B2 (en) 2004-09-02 2015-01-13 Boston Scientific Scimed, Inc. Cardiac valve, system, and method
US9370419B2 (en) 2005-02-23 2016-06-21 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US7569071B2 (en) 2005-09-21 2009-08-04 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
US9421083B2 (en) 2007-02-05 2016-08-23 Boston Scientific Scimed Inc. Percutaneous valve, system and method

Also Published As

Publication number Publication date
GB0414099D0 (en) 2004-07-28
WO2006000763A2 (en) 2006-01-05
WO2006000763A3 (en) 2006-04-27
WO2006000776A2 (en) 2006-01-05

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