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WO2006000763A3 - Biocompatible layered structures and methods for their manufacture - Google Patents

Biocompatible layered structures and methods for their manufacture Download PDF

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Publication number
WO2006000763A3
WO2006000763A3 PCT/GB2005/002455 GB2005002455W WO2006000763A3 WO 2006000763 A3 WO2006000763 A3 WO 2006000763A3 GB 2005002455 W GB2005002455 W GB 2005002455W WO 2006000763 A3 WO2006000763 A3 WO 2006000763A3
Authority
WO
WIPO (PCT)
Prior art keywords
layer
layered structures
polymer
polymer layer
applied over
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2005/002455
Other languages
French (fr)
Other versions
WO2006000763A2 (en
Inventor
David John Wheatley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Glasgow
Original Assignee
University of Glasgow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Glasgow filed Critical University of Glasgow
Publication of WO2006000763A2 publication Critical patent/WO2006000763A2/en
Publication of WO2006000763A3 publication Critical patent/WO2006000763A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12Composite materials, i.e. containing one material dispersed in a matrix of the same or different material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Flexible polymeric layered structures are disclosed. A first polymer layer (e.g. biocompatible polyurethane) is moulded over a support (e.g. a frame or another polymer layer) by drying from solution. A porous layer of polymer fibres (e.g. biocompatible polyurethane) is applied over the first polymer layer. A protective barrier layer (e.g. gold) is applied over the porous layer. A further polymer layer is applied over the porous layer, allowing attachment of the further polymer layer to the porous layer by keying. The polymer layers may be reinforced by fibres, e.g. carbon nanotubes. The layered structures are of particular use for heart valve leaflets.
PCT/GB2005/002455 2004-06-23 2005-06-22 Biocompatible layered structures and methods for their manufacture Ceased WO2006000763A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0414099.2 2004-06-23
GB0414099A GB0414099D0 (en) 2004-06-23 2004-06-23 Biocompatible layered structures and methods for their manufacture

Publications (2)

Publication Number Publication Date
WO2006000763A2 WO2006000763A2 (en) 2006-01-05
WO2006000763A3 true WO2006000763A3 (en) 2006-04-27

Family

ID=32800058

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/GB2005/002455 Ceased WO2006000763A2 (en) 2004-06-23 2005-06-22 Biocompatible layered structures and methods for their manufacture
PCT/GB2005/002476 Ceased WO2006000776A2 (en) 2004-06-23 2005-06-22 Implantable biocompatible devices and methods for their manufacture

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/GB2005/002476 Ceased WO2006000776A2 (en) 2004-06-23 2005-06-22 Implantable biocompatible devices and methods for their manufacture

Country Status (2)

Country Link
GB (1) GB0414099D0 (en)
WO (2) WO2006000763A2 (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7244242B2 (en) 2002-12-30 2007-07-17 Boston Scientific Scimed, Inc. Valve treatment catheter and methods
US7267686B2 (en) 1999-10-21 2007-09-11 Boston Scientific Scimed, Inc Implantable prosthetic valve
US7416557B2 (en) 2002-10-24 2008-08-26 Boston Scientific Scimed, Inc. Venous valve apparatus and method
US7566343B2 (en) 2004-09-02 2009-07-28 Boston Scientific Scimed, Inc. Cardiac valve, system, and method
US7569071B2 (en) 2005-09-21 2009-08-04 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
US8721717B2 (en) 2003-12-19 2014-05-13 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US9301843B2 (en) 2003-12-19 2016-04-05 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US9370419B2 (en) 2005-02-23 2016-06-21 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US9421083B2 (en) 2007-02-05 2016-08-23 Boston Scientific Scimed Inc. Percutaneous valve, system and method

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060173490A1 (en) 2005-02-01 2006-08-03 Boston Scientific Scimed, Inc. Filter system and method
US7722666B2 (en) 2005-04-15 2010-05-25 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US8012198B2 (en) 2005-06-10 2011-09-06 Boston Scientific Scimed, Inc. Venous valve, system, and method
US8133270B2 (en) 2007-01-08 2012-03-13 California Institute Of Technology In-situ formation of a valve
US8278406B2 (en) 2007-04-27 2012-10-02 Wisconsin Alumni Research Foundation Bioactive and biocompatible polyurethane-buthanediol-glycosaminoglycan salt copolymers
US7892276B2 (en) 2007-12-21 2011-02-22 Boston Scientific Scimed, Inc. Valve with delayed leaflet deployment
EP2340055B1 (en) 2008-08-19 2017-01-25 DSM IP Assets B.V. Implantable valve prosthesis and method for manufacturing such a valve
US8961599B2 (en) 2011-04-01 2015-02-24 W. L. Gore & Associates, Inc. Durable high strength polymer composite suitable for implant and articles produced therefrom
US9554900B2 (en) 2011-04-01 2017-01-31 W. L. Gore & Associates, Inc. Durable high strength polymer composites suitable for implant and articles produced therefrom
US9801712B2 (en) 2011-04-01 2017-10-31 W. L. Gore & Associates, Inc. Coherent single layer high strength synthetic polymer composites for prosthetic valves
US9744033B2 (en) 2011-04-01 2017-08-29 W.L. Gore & Associates, Inc. Elastomeric leaflet for prosthetic heart valves
US20130197631A1 (en) 2011-04-01 2013-08-01 W. L. Gore & Associates, Inc. Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom
US8945212B2 (en) * 2011-04-01 2015-02-03 W. L. Gore & Associates, Inc. Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom
US9668859B2 (en) 2011-08-05 2017-06-06 California Institute Of Technology Percutaneous heart valve delivery systems
US9554806B2 (en) 2011-09-16 2017-01-31 W. L. Gore & Associates, Inc. Occlusive devices
EP2866847B1 (en) 2012-07-02 2018-08-22 Boston Scientific Scimed, Inc. Prosthetic heart valve formation
EP2967945B1 (en) 2013-03-15 2020-10-28 California Institute of Technology Handle mechanism and functionality for repositioning and retrieval of transcatheter heart valves
US11911258B2 (en) 2013-06-26 2024-02-27 W. L. Gore & Associates, Inc. Space filling devices
WO2015053934A1 (en) * 2013-10-10 2015-04-16 Medtronic, Inc. Implantable medical devices including a polyether-polyurethane substrate with improved biostability, and methods
US9545042B2 (en) 2014-03-14 2017-01-10 Ppg Industries Ohio, Inc. P-static charge drain layer including carbon nanotubes
US10442549B2 (en) 2015-04-02 2019-10-15 Ppg Industries Ohio, Inc. Liner-type, antistatic topcoat system for aircraft canopies and windshields
US10299915B2 (en) 2015-04-09 2019-05-28 Boston Scientific Scimed, Inc. Synthetic heart valves composed of zwitterionic polymers
US10314696B2 (en) 2015-04-09 2019-06-11 Boston Scientific Scimed, Inc. Prosthetic heart valves having fiber reinforced leaflets
US10426609B2 (en) 2015-04-09 2019-10-01 Boston Scientific Scimed, Inc. Fiber reinforced prosthetic heart valve having undulating fibers
CN107847232B (en) 2015-05-14 2022-05-10 W.L.戈尔及同仁股份有限公司 Device for occluding the atrial appendage
US10716671B2 (en) 2015-07-02 2020-07-21 Boston Scientific Scimed, Inc. Prosthetic heart valve composed of composite fibers
US10413403B2 (en) 2015-07-14 2019-09-17 Boston Scientific Scimed, Inc. Prosthetic heart valve including self-reinforced composite leaflets
US10195023B2 (en) 2015-09-15 2019-02-05 Boston Scientific Scimed, Inc. Prosthetic heart valves including pre-stressed fibers
EP3429647A1 (en) 2016-03-17 2019-01-23 Centro Cardiologico Monzino Polymers and uses thereof in manufacturing of 'living' heart valves
EP3457989B1 (en) 2016-05-19 2021-09-29 Boston Scientific Scimed, Inc. Prosthetic valves, valve leaflets and related methods
CN106726008B (en) * 2017-01-04 2019-01-22 周诚 A kind of valve and preparation method thereof
US10925998B2 (en) 2017-04-25 2021-02-23 Boston Scientific Scimed, Inc. Method of manufacturing a biocompatible composite material
US11173023B2 (en) 2017-10-16 2021-11-16 W. L. Gore & Associates, Inc. Medical devices and anchors therefor
CN108014371A (en) * 2017-12-29 2018-05-11 上海纽脉医疗科技有限公司 A kind of renewable cardiac valves and its preparation facilities, method
US12245935B2 (en) 2019-11-26 2025-03-11 Boston Scientific Limited Composite web-polymer heart valve
EP4081270A4 (en) * 2019-12-26 2024-01-17 The Trustees Of Columbia University In The City Of New York BIOMIMETIC POLYMERIC COMPOSITE FOR HEART VALVE REPAIR
EP4572684A1 (en) 2022-08-16 2025-06-25 Boston Scientific Scimed, Inc. Medical device for occluding a left atrial appendage
CN120302944A (en) * 2022-12-23 2025-07-11 杭州启明医疗器械股份有限公司 Implantable material, artificial prosthesis, artificial heart valve, leaflet preform and preparation method

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3589975A (en) * 1967-03-23 1971-06-29 Reynolds Metals Co Composite sheet of plastic and metallic material and method of making the same
US4253463A (en) * 1979-10-19 1981-03-03 Kim Il B Method of reducing infection utilizing an intravascular device having antiseptic metal portion
US4388164A (en) * 1979-12-06 1983-06-14 Balzers Aktiengesellschaft Method of coating the surface of an elastic body with a continuous layer
DE3239032A1 (en) * 1982-10-21 1984-04-26 Siemens AG, 1000 Berlin und 8000 München Catheter tube
US4888009A (en) * 1985-04-05 1989-12-19 Abiomed, Inc. Prosthetic heart valve
EP0484680A1 (en) * 1990-10-09 1992-05-13 The Furukawa Electric Co., Ltd. Method of producing catheter and catheter thus obtained
US5468562A (en) * 1991-03-01 1995-11-21 Spire Corporation Metallized polymeric implant with ion embedded coating
EP1023879A2 (en) * 1999-01-29 2000-08-02 Medtronic, Inc. Implantable medical device with enhanced biocompatibility and biostability
US20030050689A1 (en) * 1999-03-05 2003-03-13 Surgica Corporation Surface-modified bioactive suppressant surgical implants
US20030055479A1 (en) * 1999-11-16 2003-03-20 Iowa-India Investments Company, Limited Encapsulated stent preform
US20030183982A1 (en) * 2000-10-09 2003-10-02 Josef Jansen Method for producing thin membrance-type structure components
WO2004011051A1 (en) * 2002-07-29 2004-02-05 Potencia Medical Ag Durable implant
US20040111144A1 (en) * 2002-12-06 2004-06-10 Lawin Laurie R. Barriers for polymeric coatings
DE10256120A1 (en) * 2002-11-29 2004-06-24 Holger Heuser Medical instrument used as an endoscope, catheter or stent has an adhesion promoting layer formed as a lacquer layer containing a plastic which corresponds to the plastic of the substrate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK229077A (en) * 1977-05-25 1978-11-26 Biocoating Aps HEARTBALL PROSTHET AND PROCEDURE FOR MANUFACTURING IT
US6755857B2 (en) * 2001-12-12 2004-06-29 Sulzer Carbomedics Inc. Polymer heart valve with perforated stent and sewing cuff

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3589975A (en) * 1967-03-23 1971-06-29 Reynolds Metals Co Composite sheet of plastic and metallic material and method of making the same
US4253463A (en) * 1979-10-19 1981-03-03 Kim Il B Method of reducing infection utilizing an intravascular device having antiseptic metal portion
US4388164A (en) * 1979-12-06 1983-06-14 Balzers Aktiengesellschaft Method of coating the surface of an elastic body with a continuous layer
DE3239032A1 (en) * 1982-10-21 1984-04-26 Siemens AG, 1000 Berlin und 8000 München Catheter tube
US4888009A (en) * 1985-04-05 1989-12-19 Abiomed, Inc. Prosthetic heart valve
EP0484680A1 (en) * 1990-10-09 1992-05-13 The Furukawa Electric Co., Ltd. Method of producing catheter and catheter thus obtained
US5468562A (en) * 1991-03-01 1995-11-21 Spire Corporation Metallized polymeric implant with ion embedded coating
EP1023879A2 (en) * 1999-01-29 2000-08-02 Medtronic, Inc. Implantable medical device with enhanced biocompatibility and biostability
US20030050689A1 (en) * 1999-03-05 2003-03-13 Surgica Corporation Surface-modified bioactive suppressant surgical implants
US20030055479A1 (en) * 1999-11-16 2003-03-20 Iowa-India Investments Company, Limited Encapsulated stent preform
US20030183982A1 (en) * 2000-10-09 2003-10-02 Josef Jansen Method for producing thin membrance-type structure components
WO2004011051A1 (en) * 2002-07-29 2004-02-05 Potencia Medical Ag Durable implant
DE10256120A1 (en) * 2002-11-29 2004-06-24 Holger Heuser Medical instrument used as an endoscope, catheter or stent has an adhesion promoting layer formed as a lacquer layer containing a plastic which corresponds to the plastic of the substrate
US20040111144A1 (en) * 2002-12-06 2004-06-10 Lawin Laurie R. Barriers for polymeric coatings

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7267686B2 (en) 1999-10-21 2007-09-11 Boston Scientific Scimed, Inc Implantable prosthetic valve
US7416557B2 (en) 2002-10-24 2008-08-26 Boston Scientific Scimed, Inc. Venous valve apparatus and method
US7244242B2 (en) 2002-12-30 2007-07-17 Boston Scientific Scimed, Inc. Valve treatment catheter and methods
US8721717B2 (en) 2003-12-19 2014-05-13 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US9301843B2 (en) 2003-12-19 2016-04-05 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7566343B2 (en) 2004-09-02 2009-07-28 Boston Scientific Scimed, Inc. Cardiac valve, system, and method
US8932349B2 (en) 2004-09-02 2015-01-13 Boston Scientific Scimed, Inc. Cardiac valve, system, and method
US9370419B2 (en) 2005-02-23 2016-06-21 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US7569071B2 (en) 2005-09-21 2009-08-04 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
US9421083B2 (en) 2007-02-05 2016-08-23 Boston Scientific Scimed Inc. Percutaneous valve, system and method

Also Published As

Publication number Publication date
GB0414099D0 (en) 2004-07-28
WO2006000763A2 (en) 2006-01-05
WO2006000776A3 (en) 2006-04-27
WO2006000776A2 (en) 2006-01-05

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