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WO2005115286A1 - Pansement auto-irrigue pour plaies - Google Patents

Pansement auto-irrigue pour plaies Download PDF

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Publication number
WO2005115286A1
WO2005115286A1 PCT/GB2005/002044 GB2005002044W WO2005115286A1 WO 2005115286 A1 WO2005115286 A1 WO 2005115286A1 GB 2005002044 W GB2005002044 W GB 2005002044W WO 2005115286 A1 WO2005115286 A1 WO 2005115286A1
Authority
WO
WIPO (PCT)
Prior art keywords
wound
reservoir
wound dressing
backing sheet
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2005/002044
Other languages
English (en)
Inventor
Deborah Addison
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethicon Inc
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Publication of WO2005115286A1 publication Critical patent/WO2005115286A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/0203—Adhesive bandages or dressings with fluid retention members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body

Definitions

  • the present invention relates to self-irrigating wound dressings.
  • Wound irrigation is an important aspect of wound treatment. Irrigation with sterile saline solutions is used to clean, humidify, and soothe wounds, and in particular to assist with the removal of adherent fragments of wound dressings or the like.
  • the saline solution may also include therapeutic agents, such as a local anaesthetic or an antiseptic.
  • Such dressings comprise : a liquid-impermeable backing sheet, a layer of adhesive on the backing sheet, and an absorbent pad (or island) applied to the adhesive-coated side of the backing sheet such that an adhesive-coated margin of the backing sheet extends around the absorbent pad for attaching the dressing to the skin of a patient around the wound to be treated.
  • WO01/12116 describes island-type wound dressings having a perforated conduit for liquids extending under the adhesive margin. Liquid can be introduced into the conduit to assist removal of the dressing by dissolving or otherwise releasing the adhesive. There is no teaching or suggestion to use such a conduit for wound irrigation.
  • US-A-2489675 describes island-type wound dressings having a reservoir of a medicament located between the absorbent pad and the backing sheet. A frangible portion of the reservoir is broken off to release the medicament immediately before the dressing is applied to a patient.
  • US-A-3580254 describes island-type dressings having a capsule of medicament located between the absorbent island and the backing sheet.
  • the capsule can be ruptured to release the medicament after the dressing has been applied to a patient There is no teaching or suggestion of using such a capsule for wound irrigation.
  • the present invention provides a wound dressing comprising: a liquid-impermeable backing sheet, a layer of adhesive on the backing sheet, an absorbent pad applied to the adhesive-coated side of the backing sheet such that an adhesive-coated margin of the backing sheet extends around the absorbent pad, and a reservoir of wound irrigation liquid situated between the absorbent pad and the backing sheet, wherein the reservoir comprises a zone of weakness whereby the irrigation liquid can be released from the reservoir while the wound dressing is attached to a patient.
  • the backing sheet is usually substantially liquid-impermeable. That is to say, it is substantially continuous and substantially free from macroscopic apertures or slits that could allow the passage of liquid water or wound fluid. However, an aperture may be present for passage of the optional reservoir pull-tab described in more detail below.
  • the backing sheet is preferably formed from a semipermeable sheet material. That is to say, the backing sheet material is preferably permeable to water vapour, but not permeable to liquid water or wound exudate. Preferably, the backing sheet material is also substantially microorganism-impermeable. Suitable continuous conformable backing sheets will preferably have a moisture vapor transmission rate (MVTR) of the backing sheet alone of
  • MVTR moisture vapor transmission rate
  • the backing sheet thickness is preferably in the range of 10 to 1000 micrometers, more preferably 100 to 500 micrometers.
  • Suitable polymers for forming the backing sheet include polyurethanes and poly alkoxyalkyl acrylates and methacrylates such as those disclosed in GB-A- 1280631.
  • the backing sheet comprises a continuous layer of a high density blocked polyurethane foam that is predominantly closed-cell.
  • a suitable backing sheet material is the polyurethane film available under the Registered Trade Mark ESTANE 5714F.
  • the backing sheet is substantially inelastic.
  • the sheet exhibits an elastic recovery at 50% strain of less than 90%, preferably less than 75%, more preferably less than 50%.
  • the backing sheet may have any shape, such as circular, oval or rectangular.
  • the backing sheet is shaped with at least one line of symmetry, and in certain embodiments the absorbent pad may be offset along a line of symmetry of the backing sheet.
  • the backing sheet is substantially rectangular (including square).
  • the backing sheet may be substantially rectangular and has dimensions of from 5 to 25 cm by from 5 to 25 cm, more preferably from 10 to 20 cm by from 10 to 20 cm.
  • the adhesive layer should be moisture vapor transmitting and/or patterned to allow passage of water vapor therethrough.
  • the adhesive layer is preferably a continuous moisture vapor transmitting, pressure-sensitive adhesive layer of the type conventionally used for island-type wound dressings, for example, a pressure sensitive adhesive based on acrylate ester copolymers, polyvinyl ethyl ether and polyurethane as described for example in GB-A- 1280631.
  • the basis weight of the adhesive layer is preferably 20 to 250 g/m 2 , and more preferably 50 to 150 g/m 2 . Polyurethane-based pressure sensitive adhesives are preferred.
  • the adhesive layer extends outwardly from the absorbent pad to form an adhesive-coated margin on the backing sheet around the adhesive island as in a conventional island dressing.
  • the wound facing surface of the absorbent island itself is substantially free of the adhesive present on the backing sheet, and more preferably it is substantially free of any adhesive.
  • the absorbent pad or island may comprise any of the layers conventionally used for absorbing wound fluids, serum or blood in the wound healing art, including gauzes, nonwoven fabrics, superabsorbents, hydrogels and mixtures thereof.
  • the absorbent pad comprises a layer of absorbent foam, such as an open celled hydrophilic polyurethane foam prepared in accordance with EP-A-0541391, the entire content of which is expressly incorporated herein by reference.
  • the absorbent pad may comprise a nonwoven fibrous web, for example a carded web of viscose staple fibers.
  • the basis weight of the absorbent pad may be in the range of 50-500g/m 2 , such as 100- 400g/m 2 .
  • the absorbent pad may comprise more than one layer.
  • it may comprise an absorbent layer laminated to a non-adherent, liquid-permeable wound contacting top sheet.
  • the uncompressed thickness of the absorbent pad may be in the range of from 0.5mm to 10mm, such as 1mm to 4mm. In some embodiments, the uncompressed thickness of the pad may be less than 3mm.
  • the free (uncompressed) liquid absorbency of the pad measured for physiological saline may for example be in the range of 5 to 30 g/g at 25°.
  • the absorbent island has at least one dimension greater than 4cm, preferably 5 to 10cm.
  • the shape of the pad likewise may be any shape, such as circular, oval or rectangular, and may be the same or different from the shape of the backing sheet.
  • the area of the absorbent pad is typically in the range of from 1cm 2 to 200cm 2 , more preferably from 4cm to 100cm . In certain embodiments, such as sacral dressings, the area of the absorbent pad is preferably greater than 16cm , more preferably greater than 20cm .
  • the wound irrigation liquid comprises a sterile saline solution, and preferably it consists essentially of such a solution.
  • the saline solution may comprise a therapeutic agent, for example selected from the group consisting of an antimicrobial agent, a pain relieving agent, a growth factor and mixtures thereof.
  • the antimicrobial agent may be selected from the group consisting of antiseptics and antibiotics and mixtures thereof.
  • Suitable antibiotics include peptide antimicrobials (e.g. defensins, Magainin, synthetic derivatives of them); antibiotics such as gentamycin, tetracycline, penicillins, terramycins, erythromycin, bacitracin, neomycin, polymycin B, mupirocin, clindamycin and mixtures thereof.
  • Suitable antiseptics include silver sulfadiazine, chlorhexidine, povidone iodine, triclosan, other silver salts and colloidal silver, sucralfate, antimicrobial quaternary ammonium salts and mixtures thereof.
  • the antimicrobial agent may be incorporated into the the wound irrigation liquid at concentrations of between about 0.1-30% by weight based on the final weight of the sponge, more suitable from about 0.5-15% by weight, and preferably from about 1 to about 5% by weight.
  • the pain relieving agent may be selected from the group consisting of an anaesthetic, an analgesic, an antiinflammatory or mixtures thereof.
  • Suitable anaesthetics include lidocaine or novocaine.
  • Suitable analgesics include non-steroidal anti-inflammatory drugs (NSAIDs).
  • Suitable antiinflammatory agents include steroids such as prostaglandins.
  • the pain relieving agent may be incorporated into the the wound irrigation liquid at concentrations of between about 0.1-30% by weight based on the final weight of the sponge, more suitably from about 0.5-15% by weight, and preferably between about 1-5% by weight.
  • the growth factor may be selected from the group consisting of platelet derived growth factor (PDGF), fibroblast growth factor (FGF), transforming growth factor beta (TGF- ⁇ ), epidermal growth factor (EGF), vascular endothelial growth factor (VEGF) and insulinlike growth factor (IGF), and mixtures thereof.
  • PDGF platelet derived growth factor
  • FGF fibroblast growth factor
  • TGF- ⁇ transforming growth factor beta
  • EGF epidermal growth factor
  • VEGF vascular endothelial growth factor
  • IGF insulinlike growth factor
  • the growth factor may be incorporated into the wound irrigation liquid at concentrations of between about lppm to about 1% by weight based on the final weight of the sponge, more suitably from about lOppm to about lOOOppm by weight.
  • the reservoir contains from about 1ml to about 40ml of the wound irrigation liquid, for example from about 4ml to about 25ml.
  • wound irrigation liquid there is preferably sufficient wound irrigation liquid to substantially saturate the absorbent pad and thereby ensure easy, pain- free removal of the dressing from the wound after use.
  • the reservoir is suitably made out of polymer sheet material, which may be shaped and filled by any of the methods conventional in the art. Suitable methods include injection molding or form-fill-seal packaging, for example vertical form-fill-seal packaging with through-liquid impulse sealing.
  • the polymer used for the reservoir sheet is conformable but not substantially elastomeric. Suitable polymers include, but are not limited to: polyolefins such as polyethylene, polypropylene, or ethylene methyl acrylate (EMA); polyesters; polyamides such as nylons; fluoropolymers such as polyvinylidene fluoride (PNDF) or polytetrafluoroethylene (PTFE); and mixtures thereof.
  • the reservoir sheet material is preferably a polyolefin film.
  • the film has a thickness by weight (ASTM E252-84) of from 10 to 200 micrometers, more preferably from 25 to 100 micrometers.
  • zone of weakness refers to a region of the reservoir that releases the liquid from the reservoir when an external force is applied to the reservoir.
  • the zone of weakness may, for example, comprise a score line in the sheet material making up the reservoir.
  • the zone of weakness may comprise a region of thinned sheet material making up the reservoir.
  • the zone of weakness may comprise a region of relatively weak sealing between two layers of sheet material making up the reservoir.
  • the zone of weakness may comprise a plug in an outlet of the reservoir that can be expelled or released by the application of a force from outside the dressing.
  • the dressing may further comprise a pull tab attached to the zone of weakness for applying a force to the zone while the dressing is attached to a patient.
  • the reservoir may be opened by applying a force through the backing sheet to increase the pressure in the reservoir to rupture the zone of weakness.
  • the wound dressing may further comprise indicia on the backing sheet showing where to apply a force to open the reservoir.
  • the wound dressing according to the invention may further comprise a channel or conduit for liquid leading from the reservoir to a wound facing surface of the dressing.
  • the channel or conduit is preferably in liquid communication with the zone of weakness in the reservoir and with the wound facing surface of the dressing.
  • the channel or conduit may extend around the edges of the absorbent pad so that the irrigation liquid bypasses the absorbent pad on its way to the wound surface. This may be achieved, for example, by leaving suitable adhesive-free regions extending down the sides of the absorbent pad.
  • the absorbent pad may be enclosed in an envelope having liquid-impermeabl back and sides and a liquid-permeable front (wound facing) surface, so that the saline from the reservoir flows around the pad onto the wound surface before being reabsorbed into the pad.
  • the channel or conduit may comprise a tube extending from the reservoir, and suitably the channel or conduit may then be formed integrally with the reservoirln
  • the zone of weakness may comprise a plug or pinch or score line in the channel that can be ruptured by applying pressure to the reservoir through the backing sheet.
  • the channel or conduit could be in the form shown in US-A-2489675 (the entire content of which is incorporated herein by reference). In use, the irrigation liquid passes down the channel or conduit onto the surface of the wound, and is then reabsorbed back into the absorbent pad thereby irrigating and cleaning the wound.
  • the wound dressing according to the present invention optionally further comprises a liquid-permeable wound facing top sheet over the absorbent pad.
  • the top sheet may be any medically acceptable wound facing sheet, including woven and nonwoven textile materials.
  • the wound facing top sheet comprises a layer of absorbent foam, such as an open celled hydrophilic polyurethane foam prepared in accordance with EP-A-0541391, the entire content of which is expressly incorporated herein by reference.
  • the wound facing top sheet comprises an apertured thermoplastic film.
  • the top sheet film may be formed from a thermoplastic film-forming polymer.
  • the polymer is conformable but not substantially elastomeric. Suitable polymers include, but are not limited to: polyolefins such as polyethylene, polypropylene, or ethylene methyl acrylate (EMA); polyesters; polyamides such as nylons; fluoropolymers such as polyvinylidene fluoride (PNDF) or polytetrafluoroethylene (PTFE); and mixtures thereof.
  • the top sheet is preferably a polyolefm film.
  • the film has a thickness by weight (ASTM E252-84) of from 10 to 200 micrometers, more preferably from 25 to 100 micrometers.
  • the top sheet of the wound dressing according to the invention is liquid permeable, but acts to block or restrict the flow of liquid from the back surface to the wound site. That is to say, the top sheet allows fluid to pass through the top sheet from the wound site, but blocks or restricts flow of the fluid back through the top sheet onto the wound (also known as wet-back).
  • Such non-wetting or top sheets may for example be made from porous non- woven fabrics comprising a layer of hydrophobic fibers, or having a hydrophobic finish applied to at least the outer surface thereof.
  • the top sheet is formed from a substantially liquid-impermeable sheet material provided with tapered capillaries, each capillary having a base substantially in the plane of the wound facing surface of the top sheet and an apical opening remote from the wound facing surface of the top sheet and preferably in contact with an absorbent layer.
  • the conical capillaries provide rapid one-way wicking of fluid from the front of the top sheet, with minimal wet-back. Top sheets of this type are described in GB-A-1526778.
  • the wound facing top sheet comprises an apertured film of water-insoluble hydrogel material.
  • the apertured sheet may be a self- supporting sheet of such a hydrogel material as described in WO03/011352, the entire content of which are incorporated herein by reference.
  • the apertures typically make up from about 0.1% to about 50% of the area of the film, more typically from about 1% to about 30% of the area of the apertured film, and preferably from about 10% to about 25% of the area of the apertured film.
  • the apertured film has from about 1 to about 30 apertures per square cm, for example from about 4 to about 15 apertures per square cm or from about 5 to about 10 apertures per square cm.
  • the apertures are uniformly distributed over the surface of the film, preferably in a regular pattern.
  • each aperture may for example be from about 0.01 to about 10 mm , preferably from about 0.1 to about 4 mm , and more preferably from about 1mm to about 2mm .
  • the apertures have a ratio of maximum length to maximum width of from about 1 to about 10, preferably from about 1 to about 3, and more preferably from about 1 to about 1.5.
  • Suitable aperture shapes include round, oval or regular polygonal
  • the wound facing top sheet may also consist of, or comprise, or be occlusively coated by, a composition that is soluble in a component of wound exudate, whereby the permeability of the wound facing sheet is dependent on the amount and/or the composition of wound exudate.
  • the composition may be soluble in water to provide increased absorption rates for highly exuding wounds, as described in GB-A-2379392.
  • the composition may be soluble in the presence of enzymes that are markers for wound chronicity, such as protease enzymes, as described in WO03/047643.
  • the composition may be soluble in the presence of enzymes that are markers for wound infection, such as lysozyme, as described in WO2004/024196.
  • the composition may be soluble in the presence of enzymes that are markers for pain, or other wound conditions.
  • the wound facing top sheet may be bonded to the backing sheet around or behind the absorbent pad, and/or it may be bonded to the absorbent pad by any suitable means, including adhesive bonding, melt bonding, needling, or entanglement.
  • a channel or conduit suitably leads from the reservoir to the wound facing surface of the top sheet.
  • the top sheet prevents the liquid from being reabsorbed by the absorbent pad too quickly, before it has properly irrigated the wound.
  • the dressings according to the present invention can be used in similar fashion to conventional island dressings, but they have the added advantage that the reservoir can be used to irrigate the wound in situ, without removing the dressing. This provides for quick, easy and mess-free wound irrigation under sterile conditions. In addition, once the absorbent pad is soaked with the irrigation liquid, it is easier to remove the dressing because the absorbent pad is less adherent to the wound surface.
  • the adhesive dressings according to the invention further comprise at least one release-coated cover sheet covering the absorbent pad and the adhesive-coated margin.
  • the dressings comprise two edge cover sheets covering opposed edges of the dressing and a central cover sheet extending between the edge cover sheets, preferably substantially as described in EP-A-0117632, the entire content of which is incorporated herein by reference.
  • the wound dressing according to the present invention usually is sterile, and may be packaged in a microorganism-impermeable container.
  • the wound dressings according to the present invention may be used in a method of treatment of a wound in a living animal or human comprising the steps of: applying a dressing according to the invention to the wound in need of treatment, followed by releasing the irrigation liquid from the reservoir to irrigate the wound.
  • the step of releasing is performed after the dressing has been applied to the wound for a suitable treatment period, for example at least 1 hour or at least 6 hours.
  • the step of releasing is followed by a step of removing the dressing e.g. once a substantial part of the irrigation liquid has been reabsorbed by the absorbent pad.
  • Fig. 1 shows a sectional schematic view of a wound dressing according to a first embodiment of the present invention
  • Fig.2 shows shows a sectional schematic view of a wound dressing according to a second embodiment of the present invention.
  • Fig.3 shows shows a sectional schematic view of the wound dressing of Fig.2 during release of the irrigation liquid from the reservoir.
  • the backing sheet 1 is formed from a microporous polyurethane sponge film of the kind conventionally used to provide a breathable but microorganism- impermeable backing to island wound dressings.
  • the backing sheet 1 is rectangular with rounded corners. The dimensions are approximately 150 mm by 150 mm, which makes the dressing suitable for protection of a human sacral region.
  • a lower surface of the backing sheet 1 is coated with a layer 2 of a medical grade pressure-sensitive adhesive.
  • An absorbent pad 3 of hydrophilic nonwoven textile fabric is located centrally on the wound facing side of the backing sheet 1.
  • a perforated thermoplastic top sheet 4 covers the absorbent pad 3. The edges 5 of the top sheet are folded back along the edges of the absorbent pad 3 and adhere to the adhesive layer 2, thereby retaining the top sheet 4 and absorbent pad 2 in place centrally on the backing sheet 1.
  • the adhesive-coated margin around the absorbent pad has an average width of about 20-50 mm.
  • the dressing further comprises a reservoir 6 filled with a sterile saline solution 9.
  • the reservoir 6 is in the form of an envelope of thermoplastic sheet material formed and filled by injection molding, or by form-fill-seal equipment (for example vertical form-fill-seal with through-liquid impulse sealing).
  • a tear strip 7 is formed in the wall of the reservoir 6, and a pull thread 8 extends along the tear strip and through the backing sheet 1 so that the end of the pull thread 8 can be grasped and pulled to open the reservoir while the dressing is attached to a patient.
  • the dressing may further comprise passages or adhesive-free channels (not shown) extending along the edges of the absorbent pad 3 and providing conduits for the passage of the sterile solution around the absorbent pad to the wound surface, from where it is then drawn back into the absorbent pad.
  • the island and the adhesive-coated margin are covered by a release-coated cover sheet 10.
  • the reservoir 12 in this embodiment comprises an integrally formed conduit 13 extending through the absorbent pad 14 and the top sheet 15.
  • the conduit comprises a collar of pressure-sensitive, waterproof adhesive 16 on an inner surface thereof, whereby the conduit is sealed by pinching this collar.
  • the saline can be released through the conduit by applying a gently force to the backing sheet to compress and pressurize the reservoir 12, thereby forcing open the conduit 13 as shown in Fig.3.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

Ce pansement pour plaies est constitué d'une feuille support, imperméable aux liquides, garnie d'une couche de colle. Contre la face collante de la feuille support se trouve une compresse absorbante disposée de façon à ménager autour d'elle une marge adhésive. un réservoir de liquide d'irrigation de la plaie. Entre la compresse absorbante absorbant et la feuille support se trouve un réservoir de liquide d'irrigation de la plaie. Une zone de faiblesse de ce réservoir permet de libérer du liquide d'irrigation tant que le pansement tient sur le patient.
PCT/GB2005/002044 2004-05-26 2005-05-25 Pansement auto-irrigue pour plaies Ceased WO2005115286A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0411794.1 2004-05-26
GB0411794A GB2414397B (en) 2004-05-26 2004-05-26 Self-irrigating wound dressing

Publications (1)

Publication Number Publication Date
WO2005115286A1 true WO2005115286A1 (fr) 2005-12-08

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Application Number Title Priority Date Filing Date
PCT/GB2005/002044 Ceased WO2005115286A1 (fr) 2004-05-26 2005-05-25 Pansement auto-irrigue pour plaies

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GB (1) GB2414397B (fr)
WO (1) WO2005115286A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008149107A1 (fr) * 2007-06-06 2008-12-11 Bristol-Myers Squibb Company Pansement
WO2010101472A1 (fr) * 2009-03-03 2010-09-10 Padtech As Tampon à barrière de fluide
US8454990B2 (en) 2008-08-01 2013-06-04 Milliken & Company Composite article suitable for use as a wound dressing
CN107970520A (zh) * 2017-12-29 2018-05-01 无锡圣诺亚科技有限公司 创口消毒装置
DE102019122159A1 (de) * 2019-08-19 2021-02-25 Adrian Abu-Ghazaleh Wundpflaster, enthaltend ein speziell ausgeführtes Reservoir für eine pharmazeutische Zubereitung

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3580254A (en) * 1967-07-13 1971-05-25 Henry P Stuart Bandage containing a medicinal material and method of using
US4499896A (en) * 1982-03-30 1985-02-19 Minnesota Mining And Manufacturing Co. Reservoir wound dressing
DE3424837C1 (de) * 1984-07-03 1986-01-16 Hassia-Verpackung Karl Klein Gmbh, 1000 Berlin Depot-Pflaster
EP0399248A2 (fr) * 1989-05-25 1990-11-28 Martin Eisenring Pansement adhésif

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5538736A (en) * 1987-04-28 1996-07-23 Lts Lohmann Therapie-Systeme Gmbh Active substance-containing plaster for the controlled administration of active substances to the skin
DE3844247A1 (de) * 1988-12-29 1990-07-12 Minnesota Mining & Mfg Vorrichtung, insbesondere pflaster zum transdermalen verabreichen eines medikaments
DE4110027C2 (de) * 1991-03-27 1996-08-29 Lohmann Therapie Syst Lts Verfahren zur Konfektionierung transdermaler therapeutischer Pflaster
GB9515807D0 (en) * 1995-08-02 1995-10-04 Cantwell Evelyna D Topical hyperbaric bandage
WO2001003619A1 (fr) * 1999-07-08 2001-01-18 Johnson & Johnson Consumer Companies, Inc. Dispositif d'administration topique exothermique

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3580254A (en) * 1967-07-13 1971-05-25 Henry P Stuart Bandage containing a medicinal material and method of using
US4499896A (en) * 1982-03-30 1985-02-19 Minnesota Mining And Manufacturing Co. Reservoir wound dressing
DE3424837C1 (de) * 1984-07-03 1986-01-16 Hassia-Verpackung Karl Klein Gmbh, 1000 Berlin Depot-Pflaster
EP0399248A2 (fr) * 1989-05-25 1990-11-28 Martin Eisenring Pansement adhésif

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008149107A1 (fr) * 2007-06-06 2008-12-11 Bristol-Myers Squibb Company Pansement
AU2008259554B2 (en) * 2007-06-06 2014-04-24 Convatec Technologies Inc. A wound dressing
US8454990B2 (en) 2008-08-01 2013-06-04 Milliken & Company Composite article suitable for use as a wound dressing
WO2010101472A1 (fr) * 2009-03-03 2010-09-10 Padtech As Tampon à barrière de fluide
US9161603B2 (en) 2009-03-03 2015-10-20 Padtech As Pad with fluid barrier
CN107970520A (zh) * 2017-12-29 2018-05-01 无锡圣诺亚科技有限公司 创口消毒装置
CN107970520B (zh) * 2017-12-29 2024-06-04 常熟市中医院（常熟市新区医院） 创口消毒装置
DE102019122159A1 (de) * 2019-08-19 2021-02-25 Adrian Abu-Ghazaleh Wundpflaster, enthaltend ein speziell ausgeführtes Reservoir für eine pharmazeutische Zubereitung
WO2021032252A1 (fr) * 2019-08-19 2021-02-25 Abu Ghazaleh Adrian Pansement adhésif contenant un réservoir spécialement conçu pour une préparation pharmaceutique

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Publication number Publication date
GB2414397B (en) 2009-03-11
GB2414397A (en) 2005-11-30
GB0411794D0 (en) 2004-06-30

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