WO2005064283A2 - Ultraschallströmungssensor mit verschränkten sende- und empfangselementen - Google Patents
Ultraschallströmungssensor mit verschränkten sende- und empfangselementen Download PDFInfo
- Publication number
- WO2005064283A2 WO2005064283A2 PCT/EP2004/053023 EP2004053023W WO2005064283A2 WO 2005064283 A2 WO2005064283 A2 WO 2005064283A2 EP 2004053023 W EP2004053023 W EP 2004053023W WO 2005064283 A2 WO2005064283 A2 WO 2005064283A2
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- WO
- WIPO (PCT)
- Prior art keywords
- flow
- ultrasonic
- transducer array
- flow sensor
- sensor according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F1/00—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow
- G01F1/66—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow by measuring frequency, phase shift or propagation time of electromagnetic or other waves, e.g. using ultrasonic flowmeters
- G01F1/665—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow by measuring frequency, phase shift or propagation time of electromagnetic or other waves, e.g. using ultrasonic flowmeters of the drag-type
Definitions
- the air flow rate in the intake or loading section of an internal combustion engine is measured by means of flow meters. Since the chemical process of combustion depends on the mass ratios of fuel and air to each other, the mass flow of air in the intake / loading tract of the internal combustion engine must be measured, for which volume or dynamic pressure measuring methods are also used.
- the maximum air mass flow to be measured is between 400 and 1200 kg per hour, depending on the engine power. Due to the low idling requirements of modern internal combustion engines, the ratio of minimum to maximum air flow is between 1:90 and 1: 100.
- Ultrasonic flow sensors are also known from the prior art, which take advantage of the beam-blocking effect within a flowing medium in order to to measure speed. Furthermore, micromechanical or film-based ultrasonic transducers or transducers are known from the prior art.
- an alternating arrangement of an ultrasound transducer which alternately act as transmitting and receiving antennas in such a way that all emitted individual sound waves interfere with common wave functions.
- the striking advantage of the alternating arrangement lies in the congruent, mutually entangled transmission and reception area achieved thereby.
- a symmetrical transmission and reception characteristic is achieved.
- the functional division of the ultrasound transducer into transmission and reception elements enables an effective separation between weak transmission signals and the strong reception signals, the amplitudes of which can differ by several orders of magnitude.
- the symmetry with regard to transmission and reception enables direct ultrasound back reflections on a surface which is aligned symmetrically to the transducer array, without the need for phase shifts between the individual transducer elements during transmission.
- the transducer array proposed according to the invention can be manufactured, for example, from a silicon substrate with micromechanically produced separating trenches between the individual transducer elements for mutual decoupling. Strip-shaped electrodes are applied to the silicon substrate, over which a PVDF film (polyvinyldenfluoride) is applied as a thickness transducer. The surface of the film is provided with a flat counter electrode and a seal for mechanical protection.
- the transmission elements of the ultrasound transducer proposed according to the invention are in direct electrical contact with one another outside the transducer array and are connected to an oscillator. As a result, the transmitting elements are able to emit ultrasound waves in phase. The individual waves interfere with common wave fronts that are flat in the first approximation and thus spread across the flowing medium.
- the opposite wall of the flow tube is curved with a radius of curvature which preferably corresponds to twice the tube diameter through which the flowing medium flows. Because of this arrangement, the ultrasound waves at the location of the transducer array are approximately collimated to a line focus, the position of which linearly depends on the speed of the flowing medium and indicates the volume flow. Since there is no ideal line focus, the receiving element with the greatest received intensity is determined. This is done with the aid of a comparator and a sample & hold amplifier, both of which can be implemented using operational amplifiers. drawing
- FIG. 1 shows an interleaved transmit and receive transducer array arranged in relation to a curved reflection surface
- FIG. 1.1 shows an embodiment variant of an evaluation circuit
- FIG. 2 shows a possible arrangement of the transducer array within a flow tube, the radius of curvature of the reflection surface corresponding to twice the tube diameter,
- FIG. 3 shows the formation of a flow-accelerating raw constriction through the arrangement of the transducer array
- FIG. 4 shows a section through a transducer substrate on which the transducer array is formed
- FIG. 6 shows a possible form of interfering wave fronts that interact with a curved reflection surface.
- An entangled transducer array shown in FIG. 1 is part of an ultrasonic flow sensor 1.
- the entangled transducer array shown is preferably made from a silicon substrate.
- Individual transducer elements 4 of the entangled transducer array 2 are decoupled from one another by trenches 3.
- the separating trenches 3 are manufactured in an electromechanical manner.
- Strip-shaped electrodes are located on the silicon substrate representing the entangled transducer array 2 (cf. FIG. 4, position 11).
- the strip-shaped electrodes 5 are covered with a PVDF film 6 (polyvinylhide fluoride), which serves as a thickness transducer.
- the top of the PVDF film 6 (polyvinylidene fluoride) is provided with a flat counter electrode 7 and a seal 12 for mechanical protection.
- the seal 12 can be made of epoxy resin or silicone, for example are made, while the counter electrode 7 is preferably made of gold or aluminum.
- the strip-shaped electrodes 5 can be made of aluminum, gold or platinum, while the carrier substrate for the ultrasound transducer array 2 is preferably a silicon substrate.
- shielding electrodes can be provided between the transmitting or receiving electrodes of the ultrasound transducer array 2, as a result of which not only a mechanical but also an electrical coupling can be achieved.
- the silicon substrate 11, a strip-shaped electrode 5, a region of the PVDF film 6, a region of the counterelectrode 7 and possibly also the seal 12 applied to it belong under a transmission element 10 (cf. illustration in FIG. 4) and, if appropriate, the seal 12 applied thereon the region between two adjacent dividing trenches 3.
- the transmission elements of the entangled converter array 2 in the illustration according to FIG. 1 are designated by reference number 10.
- All of the transmission elements 10 are in direct electrical contact with one another outside of the interleaved converter array 2.
- the transmission elements 10 are also connected to an oscillator 26, so that the transmission of in-phase ultrasound waves is possible.
- the interdigitated converter array 2 is oriented perpendicular to the flow direction 14 of the flowing medium.
- Opposite the entangled transducer array 2 is a curved reflection surface 13 (see also illustration according to FIG. 2).
- the transmitted signal is identified by reference number 15, while the received signal is identified by reference number 16.
- the in-phase ultrasound waves 27 emanating from the transmission elements 10 of the entangled transducer array 2 interfere with common wave fronts 28.
- the interference phenomena depend on the spatial and temporal course of the ultrasound waves due to deflections of the molecules in the air.
- the ultrasonic individual waves 27 interfering to wave fronts 28 are flat in a first approximation and therefore spread relatively directed transversely to the flowing medium, which flows in the direction of flow 14.
- the spreading common wave fronts 28 fall on an opposite wall of a flow tube 17, which has a radius of curvature 19.
- the position 30 of the line focus 29 depends linearly on the speed of the medium flowing in the direction of flow 14.
- a first line focus 29 is drawn in at position X 0 , which occurs without a flowing medium.
- the first line focus 29.1 shifts along the X axis to the position identified by reference symbol 29.2 (cf. position i on the X axis).
- the deflection of the line focus from position 29.1 in 29.2 is based on the deflection by the medium flowing in the direction of flow 14.
- Reference symbols 28 denote the interfering wavefronts which spread in the direction of a curved reflection surface 13.
- FIG. 1.1 shows an evaluation circuit in a schematic manner.
- the evaluation circuit as shown in FIG. 1.1 comprises a signal multiplexer 34, which is connected to the entangled converter array 2.
- the signal multiplexer 34 is followed by a signal processor 36 and a comparator 31.
- a sample and hold amplifier 32 which can also be designed as an operational amplifier, that of the receiving elements with the highest received ultrasound signal intensity can be determined.
- the signal multiplexer 34 can be controlled via a multiplexer controller 35.
- Ui denotes the input voltage signal which is tapped at the entangled converter array 2; with U 2 the voltage signal on the output side of the sample and hold amplifier 32.
- the center of gravity of the intensity distribution can also be determined, which is established across all strip-shaped electrodes 5 of the entangled transducer array 2 of the ultrasonic flow sensor 1.
- FIG. 2 shows a cross section through a flow tube in which an interleaved ultrasonic transducer array proposed according to the invention is accommodated.
- the flow tube 24 is delimited by a wall and has a diameter 18 (cf. d).
- the reflection surface 13, which has a curvature 23, is integrated into the wall of the flow tube 24.
- the radius of curvature 19 of the reflection surface 13 is preferably twice the tube diameter 18.
- the entangled transducer array 2 is integrated into a wall of the flow tube 24 in the illustration according to FIG.
- the direction of flow of the flowing medium, its flow rate or volume lumen flow is to be determined is indicated by reference numeral 14 and runs from right to left in the illustration according to FIG.
- Reference number 17 denotes an auxiliary circle which has a radius of approximately twice the diameter 18 of the flow tube 24.
- the auxiliary circle 17 serves to indicate the curvature of the arched reflection surface 13.
- the representation according to FIG. 2 shows the differing wavefronts 28 emanating from the entangled transducer array 2, which move towards the curved reflection surface 13 formed in the curvature 23, as well as the wavefronts 28 reflected by the latter on the reception elements of the entangled transducer array 2.
- Figure 3 shows a variant of an entangled transducer array with a flow-accelerating pipe constriction.
- FIG. 3 shows that the entangled transducer array 2 is accommodated in a surface within the tube wall of the flow tube 24, which is formed in a curve 23.
- the curvature 23 form a surface depression within the tube wall of the flow tube 24, so that the flow cross section between the bottom 9 of the entangled transducer array 2 and the top of the reflection surface 13 is narrowed, indicated by the distance 25 di, which is smaller than that in the figure 2 shown distance 18 d between the flow tube 24 and the top of the reflection surface 13 integrated into the wall.
- a cross-sectional narrowing results within the flow tube 24, so that the cross-section of curvature below the entangled transducer array 2 is narrowed overall and the flow in flow direction 14 is accelerated.
- a deposit of particles such as dust or the like on the inside of the wall of the flow tube 24 and on the underside 9 of the entangled transducer array 2 can thereby be effectively prevented.
- the formation of a curvature in the reflection surface 13 to bring about a SttaM collimation can be dispensed with if the individual transducer elements of the ultrasonic flow sensor are excited with a phase delay such that the path difference between the individual ultrasonic waves 27 results in a curved or flat wavefront 28 (cf. Figures 5 and 6). If these wave fronts 28 have a radius of curvature immediately after their emission, which is twice as large as the tube diameter, then after reflection at the opposite one, the waves converge into a line focus 29 at the location of the limited transducer array 2. The determination of the receiving element with the highest intensity was mentioned above. Instead, a focus on the intensity distribution of the received signal could also be determined and the measurement resolution could thus be improved.
- the reflection curvature 13 results in a cross-sectional widening and thus a local reduction in the flow velocity of the flowing medium in the flow direction 14 in the flow tube 24. This can lead to an increased deposition of particles such as dust in individual cases. The deposition of dust and other particles carried in the flowing medium can be prevented by the embodiment shown in FIG. 3.
- the inventive design of an entangled transducer array 2 enables an alternating arrangement of ultrasound transducers, which alternately act as transmit and receive antennas in such a way that all emitted individual sound waves 27 can interfere with common ultrasonic wave fronts 28.
- the advantage of the proposed alternating arrangement lies in the congruent, mutually entangled transmission and reception range achieved thereby, whereby a symmetrical transmission and reception arrangement can be achieved in combination with a single ultrasound reflection within the flow tube 24.
- the functional division into transmission and reception elements advantageously enables a separation between the weak transmission and the strong reception signals, the amplitudes of which can differ from one another by several orders of magnitude.
- the symmetry with regard to transmission and reception enables direct ultrasound back reflections on a surface which is aligned symmetrically to the ultrasound transducer array, without the need for a phase shift between the individual transducer elements during transmission.
- FIG. 4 shows a cross section through a transducer element 4. Individual trenches 3 are formed in the silicon substrate 11.
- the strip-shaped electrodes 5 run on the upper side of the silicon substrate 11, above which the PVDF film 6 is applied.
- the flat counterelectrode 7 Above the PVDF foil 6 is the flat counterelectrode 7, which is made of a metallic material, for example gold, aluminum or platinum.
- a seal 12 in the form of an epoxy protective layer can be applied to the top of the flat counter electrode 7.
- Reference number 10 denotes the top of a transmission element shown by way of example in FIG.
- the silicon substrate 11, which is the carrier substrate has a much greater thickness.
- FIG. 5 shows individual ultrasonic waves 27 emanating from transmitting elements 10, which due to their mutual overlap form an interfering wavefront 28 unite.
- the interfering wavefront 28 that forms runs essentially parallel.
- the individual ultrasonic waves shown in FIG. 6 run as curved wave fronts 28 due to a phase shift for collimation without a curved reflection surface 13.
- ultrasonic flow sensor 36 analog signal processing 2 entangled transducer array 3 separating trench 4 transducer element 5 rod-shaped electrode 6 PVDF film 7 flat counter electrode 8 top side 9 bottom side 10 transmission element 11 silicon substrate 12 epoxy resin protective layer 13 reflection surface 14 flow direction 15 signal sent 16 received signal 17 auxiliary circuit
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- Physics & Mathematics (AREA)
- Electromagnetism (AREA)
- Fluid Mechanics (AREA)
- General Physics & Mathematics (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Measuring Volume Flow (AREA)
- Transducers For Ultrasonic Waves (AREA)
Abstract
Description
Claims
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006546141A JP2007517207A (ja) | 2003-12-29 | 2004-11-19 | 交差式の送信および受信素子を有する超音波流れセンサ |
| DE502004011348T DE502004011348D1 (de) | 2003-12-29 | 2004-11-19 | Ultraschallströmungssensor mit verschränkten sende- und empfangselementen |
| EP04820844A EP1716394B1 (de) | 2003-12-29 | 2004-11-19 | Ultraschallströmungssensor mit verschränkten sende- und empfangselementen |
| US10/583,903 US7500403B2 (en) | 2003-12-29 | 2004-11-19 | Ultrasonic flow sensor having interlaid transmitting and receiving elements |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10361763.9 | 2003-12-29 | ||
| DE10361763A DE10361763A1 (de) | 2003-12-29 | 2003-12-29 | Ultraschallströmungssensor mit verschränkten Sende- und Empfangselementen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2005064283A2 true WO2005064283A2 (de) | 2005-07-14 |
| WO2005064283A3 WO2005064283A3 (de) | 2005-09-09 |
Family
ID=34706699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP2004/053023 Ceased WO2005064283A2 (de) | 2003-12-29 | 2004-11-19 | Ultraschallströmungssensor mit verschränkten sende- und empfangselementen |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7500403B2 (de) |
| EP (1) | EP1716394B1 (de) |
| JP (1) | JP2007517207A (de) |
| DE (2) | DE10361763A1 (de) |
| WO (1) | WO2005064283A2 (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008000577A1 (de) * | 2006-06-26 | 2008-01-03 | Continental Automotive Gmbh | Verfahren und vorrichtung zum messen eines luftmassenstroms mittels ultraschall |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004013251A1 (de) * | 2004-03-18 | 2005-10-06 | Robert Bosch Gmbh | Ultraschall-Strömungssensor mit Wandlerarray und Reflexionsfläche |
| US8968204B2 (en) * | 2006-06-12 | 2015-03-03 | Transonic Systems, Inc. | System and method of perivascular pressure and flow measurement |
| DE102007016408A1 (de) * | 2007-03-26 | 2008-10-02 | Ident Technology Ag | Mobiles Kommunikationsgerät und Eingabeeinrichtung hierfür |
| US8517990B2 (en) | 2007-12-18 | 2013-08-27 | Hospira, Inc. | User interface improvements for medical devices |
| EP2375223B1 (de) * | 2009-01-06 | 2020-09-30 | Panasonic Corporation | Durchsatzmessvorrichtung |
| US8857269B2 (en) | 2010-08-05 | 2014-10-14 | Hospira, Inc. | Method of varying the flow rate of fluid from a medical pump and hybrid sensor system performing the same |
| EP2745204A4 (de) | 2011-08-19 | 2015-01-07 | Hospira Inc | Systeme und verfahren für eine grafische schnittstelle mit einer grapfischen darstellung medizinischer daten |
| WO2013090709A1 (en) | 2011-12-16 | 2013-06-20 | Hospira, Inc. | System for monitoring and delivering medication to a patient and method of using the same to minimize the risks associated with automated therapy |
| CA2868801C (en) | 2012-03-30 | 2021-07-13 | Hospira, Inc. | Air detection system and method for detecting air in a pump of an infusion system |
| ES3028431T3 (en) | 2012-07-31 | 2025-06-19 | Icu Medical Inc | Patient care system for critical medications |
| CA2913421C (en) | 2013-05-24 | 2022-02-15 | Hospira, Inc. | Multi-sensor infusion system for detecting air or an occlusion in the infusion system |
| AU2014274146B2 (en) | 2013-05-29 | 2019-01-24 | Icu Medical, Inc. | Infusion system which utilizes one or more sensors and additional information to make an air determination regarding the infusion system |
| AU2014274122A1 (en) | 2013-05-29 | 2016-01-21 | Icu Medical, Inc. | Infusion system and method of use which prevents over-saturation of an analog-to-digital converter |
| US9343898B2 (en) * | 2013-07-19 | 2016-05-17 | Texas Instruments Incorporated | Driver current control apparatus and methods |
| ES2776363T3 (es) | 2014-02-28 | 2020-07-30 | Icu Medical Inc | Sistema de infusión y método que utiliza detección óptica de aire en línea de doble longitud de onda |
| JP2017517302A (ja) | 2014-05-29 | 2017-06-29 | ホスピーラ インコーポレイテッド | 構成可能閉ループ送達速度キャッチアップを有する注入システムおよびポンプ |
| DE102014118187A1 (de) * | 2014-12-09 | 2016-06-09 | Endress + Hauser Flowtec Ag | Ultraschall-Durchflussmessgerät |
| US11344668B2 (en) | 2014-12-19 | 2022-05-31 | Icu Medical, Inc. | Infusion system with concurrent TPN/insulin infusion |
| US10850024B2 (en) | 2015-03-02 | 2020-12-01 | Icu Medical, Inc. | Infusion system, device, and method having advanced infusion features |
| CN106908104A (zh) * | 2015-12-23 | 2017-06-30 | 江苏迈拓智能仪表有限公司 | 一种插杆式超声波流量传感器结构 |
| CA3023658C (en) | 2016-05-13 | 2023-03-07 | Icu Medical, Inc. | Infusion pump system and method with common line auto flush |
| WO2017214441A1 (en) | 2016-06-10 | 2017-12-14 | Icu Medical, Inc. | Acoustic flow sensor for continuous medication flow measurements and feedback control of infusion |
| US10705656B2 (en) * | 2017-09-29 | 2020-07-07 | Qualcomm Incorporated | System and method for ultrasonic sensing |
| US10089055B1 (en) | 2017-12-27 | 2018-10-02 | Icu Medical, Inc. | Synchronized display of screen content on networked devices |
| US11278671B2 (en) | 2019-12-04 | 2022-03-22 | Icu Medical, Inc. | Infusion pump with safety sequence keypad |
| CA3189781A1 (en) | 2020-07-21 | 2022-01-27 | Icu Medical, Inc. | Fluid transfer devices and methods of use |
| US11135360B1 (en) | 2020-12-07 | 2021-10-05 | Icu Medical, Inc. | Concurrent infusion with common line auto flush |
| USD1091564S1 (en) | 2021-10-13 | 2025-09-02 | Icu Medical, Inc. | Display screen or portion thereof with graphical user interface for a medical device |
| CA3241894A1 (en) | 2021-12-10 | 2023-06-15 | Icu Medical, Inc. | Medical fluid compounding systems with coordinated flow control |
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| US4200858A (en) * | 1976-12-28 | 1980-04-29 | Canon Kabushiki Kaisha | Acoustic wave scanning apparatus |
| JPS54143260A (en) * | 1978-04-28 | 1979-11-08 | Toshiba Corp | Ultrasonic flowmeter |
| JPS5516433U (de) * | 1978-07-20 | 1980-02-01 | ||
| JPS567016A (en) * | 1979-06-30 | 1981-01-24 | Toshiba Corp | Simple-shaped pipe inside flow meter |
| JPS57198826A (en) * | 1981-05-22 | 1982-12-06 | Siemens Ag | Ultrasonic flowmeter |
| EP0068961A3 (de) * | 1981-06-26 | 1983-02-02 | Thomson-Csf | Vorrichtung zur lokalen Erwärmung von biologischen Gewebe |
| JPS60260847A (ja) * | 1984-06-07 | 1985-12-24 | Nippon Dempa Kogyo Co Ltd | 超音波探触子 |
| US4719476A (en) * | 1986-04-17 | 1988-01-12 | Xerox Corporation | Spatially addressing capillary wave droplet ejectors and the like |
| DE4010148A1 (de) * | 1990-03-29 | 1991-10-02 | Siemens Ag | Verbesserung fuer einen ultraschall-gas-/fluessigkeits-durchflussmesser |
| DE4416826A1 (de) * | 1994-05-16 | 1995-11-23 | Steffen Dipl Ing Schulze | Neuartiges Ultraschallsystem zur Bestimmung der Strömungsgeschwindigkeit in Gasen und Flüssigkeiten |
| US5677491A (en) * | 1994-08-08 | 1997-10-14 | Diasonics Ultrasound, Inc. | Sparse two-dimensional transducer array |
| US5807258A (en) * | 1997-10-14 | 1998-09-15 | Cimochowski; George E. | Ultrasonic sensors for monitoring the condition of a vascular graft |
| JP2000253496A (ja) * | 1999-03-03 | 2000-09-14 | Ge Yokogawa Medical Systems Ltd | アレイ型超音波トランスデューサおよびその製造方法 |
| EP1350077B1 (de) * | 2001-01-09 | 2006-11-22 | Landis+Gyr GmbH | Durchflussmesser |
| US7857763B2 (en) * | 2005-02-08 | 2010-12-28 | Alan Chi-Chung Tai | Automatic signal-optimizing transducer assembly for blood flow measurement |
-
2003
- 2003-12-29 DE DE10361763A patent/DE10361763A1/de not_active Withdrawn
-
2004
- 2004-11-19 EP EP04820844A patent/EP1716394B1/de not_active Expired - Lifetime
- 2004-11-19 WO PCT/EP2004/053023 patent/WO2005064283A2/de not_active Ceased
- 2004-11-19 JP JP2006546141A patent/JP2007517207A/ja not_active Ceased
- 2004-11-19 DE DE502004011348T patent/DE502004011348D1/de not_active Expired - Lifetime
- 2004-11-19 US US10/583,903 patent/US7500403B2/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008000577A1 (de) * | 2006-06-26 | 2008-01-03 | Continental Automotive Gmbh | Verfahren und vorrichtung zum messen eines luftmassenstroms mittels ultraschall |
Also Published As
| Publication number | Publication date |
|---|---|
| US20080028868A1 (en) | 2008-02-07 |
| US7500403B2 (en) | 2009-03-10 |
| EP1716394A2 (de) | 2006-11-02 |
| DE502004011348D1 (de) | 2010-08-12 |
| EP1716394B1 (de) | 2010-06-30 |
| DE10361763A1 (de) | 2005-07-28 |
| JP2007517207A (ja) | 2007-06-28 |
| WO2005064283A3 (de) | 2005-09-09 |
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