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WO2004091542A3 - Composes de ciblage d'integrine contenant de l'azote - Google Patents

Composes de ciblage d'integrine contenant de l'azote Download PDF

Info

Publication number
WO2004091542A3
WO2004091542A3 PCT/US2004/012034 US2004012034W WO2004091542A3 WO 2004091542 A3 WO2004091542 A3 WO 2004091542A3 US 2004012034 W US2004012034 W US 2004012034W WO 2004091542 A3 WO2004091542 A3 WO 2004091542A3
Authority
WO
WIPO (PCT)
Prior art keywords
integrin targeting
nitrogen containing
targeting compounds
containing integrin
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/012034
Other languages
English (en)
Other versions
WO2004091542A2 (fr
Inventor
Amir Tamiz
Curt W Bradshaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Covx Pharmaceuticals Inc
Original Assignee
Covx Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Covx Pharmaceuticals Inc filed Critical Covx Pharmaceuticals Inc
Publication of WO2004091542A2 publication Critical patent/WO2004091542A2/fr
Publication of WO2004091542A3 publication Critical patent/WO2004091542A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne des composés de ciblage d'intégrine comprenant un faible poids moléculaire de conjugués liant-agent de ciblage d'intégrine qui sont liés à un polymère tel qu'une protéine. L'invention a également pour objet différentes utilisations des composés de l'invention, y compris des procédés pour prévenir ou traiter le cancer ou d'autres maladies.
PCT/US2004/012034 2003-04-15 2004-04-15 Composes de ciblage d'integrine contenant de l'azote Ceased WO2004091542A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US46345603P 2003-04-15 2003-04-15
US60/463,456 2003-04-15
US50788703P 2003-09-30 2003-09-30
US60/507,887 2003-09-30

Publications (2)

Publication Number Publication Date
WO2004091542A2 WO2004091542A2 (fr) 2004-10-28
WO2004091542A3 true WO2004091542A3 (fr) 2005-04-14

Family

ID=33303121

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/012034 Ceased WO2004091542A2 (fr) 2003-04-15 2004-04-15 Composes de ciblage d'integrine contenant de l'azote

Country Status (1)

Country Link
WO (1) WO2004091542A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5167473B2 (ja) * 2005-03-03 2013-03-21 コヴェックス・テクノロジーズ・アイルランド・リミテッド 抗血管新生化合物
EP1871741A4 (fr) * 2005-04-04 2012-01-11 Daiamed Inc Azetidinones substituees
US8741566B2 (en) 2005-07-01 2014-06-03 Dako Denmark A/S Immunohistochemistry and in situ hybridization detection method
WO2008098788A2 (fr) * 2007-02-16 2008-08-21 Ktb Tumorforschungsgesellschaft Mbh Récepteur et promédicament ciblé par l'antigène
ES2435779T3 (es) 2007-07-19 2013-12-23 Sanofi Agentes citotóxicos que comprenden nuevos derivados de tomaimicina y su uso terapéutico
WO2010093706A2 (fr) * 2009-02-10 2010-08-19 The Scripps Research Institute Vaccination programmée chimiquement
CN106565825A (zh) * 2015-10-12 2017-04-19 复旦大学 稳定化a7r多肽及其在构建肿瘤靶向诊治递药系统中的用途
CN114478420B (zh) * 2020-11-13 2025-02-07 北京大学 多特异生物偶联连接臂及其合成方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048861A (en) * 1997-12-17 2000-04-11 Merck & Co., Inc. Integrin receptor antagonists

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048861A (en) * 1997-12-17 2000-04-11 Merck & Co., Inc. Integrin receptor antagonists

Also Published As

Publication number Publication date
WO2004091542A2 (fr) 2004-10-28

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