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WO2004091542A3 - Nitrogen containing integrin targeting compounds - Google Patents

Nitrogen containing integrin targeting compounds Download PDF

Info

Publication number
WO2004091542A3
WO2004091542A3 PCT/US2004/012034 US2004012034W WO2004091542A3 WO 2004091542 A3 WO2004091542 A3 WO 2004091542A3 US 2004012034 W US2004012034 W US 2004012034W WO 2004091542 A3 WO2004091542 A3 WO 2004091542A3
Authority
WO
WIPO (PCT)
Prior art keywords
integrin targeting
nitrogen containing
targeting compounds
containing integrin
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/012034
Other languages
French (fr)
Other versions
WO2004091542A2 (en
Inventor
Amir Tamiz
Curt W Bradshaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Covx Pharmaceuticals Inc
Original Assignee
Covx Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Covx Pharmaceuticals Inc filed Critical Covx Pharmaceuticals Inc
Publication of WO2004091542A2 publication Critical patent/WO2004091542A2/en
Publication of WO2004091542A3 publication Critical patent/WO2004091542A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention provides integrin targeting compounds which comprise small molecular weight integrin targeting agent-linker conjugates which are linked to a polymer such as a protein. Various uses of the invention compounds are provided, including methods to prevent or treat cancer or other disease.
PCT/US2004/012034 2003-04-15 2004-04-15 Nitrogen containing integrin targeting compounds Ceased WO2004091542A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US46345603P 2003-04-15 2003-04-15
US60/463,456 2003-04-15
US50788703P 2003-09-30 2003-09-30
US60/507,887 2003-09-30

Publications (2)

Publication Number Publication Date
WO2004091542A2 WO2004091542A2 (en) 2004-10-28
WO2004091542A3 true WO2004091542A3 (en) 2005-04-14

Family

ID=33303121

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/012034 Ceased WO2004091542A2 (en) 2003-04-15 2004-04-15 Nitrogen containing integrin targeting compounds

Country Status (1)

Country Link
WO (1) WO2004091542A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5167473B2 (en) * 2005-03-03 2013-03-21 コヴェックス・テクノロジーズ・アイルランド・リミテッド Anti-angiogenic compounds
EP1871741A4 (en) * 2005-04-04 2012-01-11 Daiamed Inc AZETIDINONES SUBSTITUTED
US8741566B2 (en) 2005-07-01 2014-06-03 Dako Denmark A/S Immunohistochemistry and in situ hybridization detection method
WO2008098788A2 (en) * 2007-02-16 2008-08-21 Ktb Tumorforschungsgesellschaft Mbh Receptor and antigen targeted prodrug
ES2435779T3 (en) 2007-07-19 2013-12-23 Sanofi Cytotoxic agents comprising new tomaimycin derivatives and their therapeutic use
WO2010093706A2 (en) * 2009-02-10 2010-08-19 The Scripps Research Institute Chemically programmed vaccination
CN106565825A (en) * 2015-10-12 2017-04-19 复旦大学 Stabilized A7R polypeptide and application of polypeptide in construction of tumor targeted diagnosis and treatment drug delivery system
CN114478420B (en) * 2020-11-13 2025-02-07 北京大学 Multispecific bioconjugate linker and synthesis method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048861A (en) * 1997-12-17 2000-04-11 Merck & Co., Inc. Integrin receptor antagonists

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048861A (en) * 1997-12-17 2000-04-11 Merck & Co., Inc. Integrin receptor antagonists

Also Published As

Publication number Publication date
WO2004091542A2 (en) 2004-10-28

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