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WO2003035862A3 - Regulation of human arginase signature-containing protein - Google Patents

Regulation of human arginase signature-containing protein Download PDF

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Publication number
WO2003035862A3
WO2003035862A3 PCT/EP2002/011947 EP0211947W WO03035862A3 WO 2003035862 A3 WO2003035862 A3 WO 2003035862A3 EP 0211947 W EP0211947 W EP 0211947W WO 03035862 A3 WO03035862 A3 WO 03035862A3
Authority
WO
WIPO (PCT)
Prior art keywords
signature
containing protein
human arginase
regulation
reagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2002/011947
Other languages
French (fr)
Other versions
WO2003035862A2 (en
Inventor
Timothy J Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer Healthcare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare AG filed Critical Bayer Healthcare AG
Publication of WO2003035862A2 publication Critical patent/WO2003035862A2/en
Publication of WO2003035862A3 publication Critical patent/WO2003035862A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Reagents that regulate human arginase signature-containing protein and reagents which bind to human arginase signature-containing protein gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cardiovascular disorders.
PCT/EP2002/011947 2001-10-26 2002-10-25 Regulation of human arginase signature-containing protein Ceased WO2003035862A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33062001P 2001-10-26 2001-10-26
US60/330,620 2001-10-26

Publications (2)

Publication Number Publication Date
WO2003035862A2 WO2003035862A2 (en) 2003-05-01
WO2003035862A3 true WO2003035862A3 (en) 2003-12-24

Family

ID=23290550

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/011947 Ceased WO2003035862A2 (en) 2001-10-26 2002-10-25 Regulation of human arginase signature-containing protein

Country Status (1)

Country Link
WO (1) WO2003035862A2 (en)

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 11 November 2000 (2000-11-11), "Homo sapiens mRNA for KIAA1173 protein, complete cds", XP002246960, retrieved from EBI Database accession no. AB042554 *
DATABASE EMBL [online] 13 February 2002 (2002-02-13), DRMANAC ET AL: "New isolated polynucleotide...", XP002246986, retrieved from EBI Database accession no. ABG04239 *
DATABASE SWISS-PROT [online] EBI; July 1998 (1998-07-01), "Arginase family signature 1", XP002246961, Database accession no. PS00147 *
DATABASE SWISS-PROT [online] EBI; July 1998 (1998-07-01), "Arginase family signature 2", XP002246962, Database accession no. PS00148 *
DATABASE SWISS-PROT [online] EBI; July 1998 (1998-07-01), "Arginase family signature 3", XP002246963, Database accession no. PS01053 *
LI ET AL: "Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells", AM J PHYSIOL ENDOCRINOL METAB, vol. 280, January 2001 (2001-01-01), pages E75 - E82, XP002246959 *

Also Published As

Publication number Publication date
WO2003035862A2 (en) 2003-05-01

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