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WO2002018566A3 - Regulation of human l-asparaginase-like enzyme - Google Patents

Regulation of human l-asparaginase-like enzyme Download PDF

Info

Publication number
WO2002018566A3
WO2002018566A3 PCT/EP2001/009607 EP0109607W WO0218566A3 WO 2002018566 A3 WO2002018566 A3 WO 2002018566A3 EP 0109607 W EP0109607 W EP 0109607W WO 0218566 A3 WO0218566 A3 WO 0218566A3
Authority
WO
WIPO (PCT)
Prior art keywords
asparaginase
human
enzyme
regulation
reagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/009607
Other languages
French (fr)
Other versions
WO2002018566A2 (en
Inventor
Timothy J Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to AU2001282109A priority Critical patent/AU2001282109A1/en
Publication of WO2002018566A2 publication Critical patent/WO2002018566A2/en
Publication of WO2002018566A3 publication Critical patent/WO2002018566A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/82—Asparaginase (3.5.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Reagents which regulate human L-asparaginase-like enzyme and reagents which bind to human L-asparaginase-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer and CNS disorders.
PCT/EP2001/009607 2000-08-31 2001-08-21 Regulation of human l-asparaginase-like enzyme Ceased WO2002018566A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001282109A AU2001282109A1 (en) 2000-08-31 2001-08-21 Regulation of human l-asparaginase-like enzyme

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22905500P 2000-08-31 2000-08-31
US60/229,055 2000-08-31

Publications (2)

Publication Number Publication Date
WO2002018566A2 WO2002018566A2 (en) 2002-03-07
WO2002018566A3 true WO2002018566A3 (en) 2003-01-30

Family

ID=22859671

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/009607 Ceased WO2002018566A2 (en) 2000-08-31 2001-08-21 Regulation of human l-asparaginase-like enzyme

Country Status (2)

Country Link
AU (1) AU2001282109A1 (en)
WO (1) WO2002018566A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001016334A2 (en) * 1999-09-01 2001-03-08 Incyte Genomics, Inc. Human hydrolytic enzymes
WO2001053312A1 (en) * 1999-12-23 2001-07-26 Hyseq, Inc. Novel nucleic acids and polypeptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001016334A2 (en) * 1999-09-01 2001-03-08 Incyte Genomics, Inc. Human hydrolytic enzymes
WO2001053312A1 (en) * 1999-12-23 2001-07-26 Hyseq, Inc. Novel nucleic acids and polypeptides

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EBI [online] 1 October 2000 (2000-10-01), XP002213531, Database accession no. Q9NXJ2 *
DATABASE EBI [online] 22 February 2000 (2000-02-22), WATANABE ET AL: "NEDO human cDNA sequencing project", XP002213530, Database accession no. AK000219 *
DATABASE EBI [online] 22 October 2001 (2001-10-22), XP002213532, Database accession no. AAM40221 *
DATABASE EBI [online] 22 October 2001 (2001-10-22), XP002213533, Database accession no. AAI61163 *

Also Published As

Publication number Publication date
WO2002018566A2 (en) 2002-03-07
AU2001282109A1 (en) 2002-03-13

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