[go: up one dir, main page]

WO2003061365A3 - Acide nucleique codant pour un recepteur couple a la proteine g, et ses utilisations - Google Patents

Acide nucleique codant pour un recepteur couple a la proteine g, et ses utilisations Download PDF

Info

Publication number
WO2003061365A3
WO2003061365A3 PCT/US2003/001694 US0301694W WO03061365A3 WO 2003061365 A3 WO2003061365 A3 WO 2003061365A3 US 0301694 W US0301694 W US 0301694W WO 03061365 A3 WO03061365 A3 WO 03061365A3
Authority
WO
WIPO (PCT)
Prior art keywords
coupled receptor
protein
nucleic acid
acid encoding
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2003/001694
Other languages
English (en)
Other versions
WO2003061365A2 (fr
Inventor
Haifeng Eishingdrelo
Jidong Cai
Anthony Sandrasagra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Aventis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0210597.1A external-priority patent/GB0210597D0/en
Priority to KR10-2004-7011461A priority Critical patent/KR20040077791A/ko
Priority to CA002473707A priority patent/CA2473707A1/fr
Priority to JP2003561321A priority patent/JP2005514934A/ja
Priority to BR0307122-7A priority patent/BR0307122A/pt
Priority to EP03710699A priority patent/EP1470420A4/fr
Application filed by Aventis Pharmaceuticals Inc filed Critical Aventis Pharmaceuticals Inc
Priority to MXPA04007117A priority patent/MXPA04007117A/es
Publication of WO2003061365A2 publication Critical patent/WO2003061365A2/fr
Publication of WO2003061365A3 publication Critical patent/WO2003061365A3/fr
Priority to NO20043123A priority patent/NO20043123L/no
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La présente invention concerne un récepteur couplé à la protéine G nouveau et utile impliqué dans la transduction du signal par rapport à l'inflammation et à la réponse immunologique physiologique. L'invention concerne également des procédés d'utilisation du récepteur pour le criblage de molécules susceptibles de moduler l'activité du récepteur. De telles molécules peuvent aisément trouver des applications dans une grande variété de maladies et de troubles liés à l'inflammation et aux mécanismes immunitaires
PCT/US2003/001694 2002-01-23 2003-01-21 Acide nucleique codant pour un recepteur couple a la proteine g, et ses utilisations Ceased WO2003061365A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
MXPA04007117A MXPA04007117A (es) 2002-01-23 2003-01-21 Un acido nucleico que codifica un receptor acoplado a la proteina g, y sus usos.
CA002473707A CA2473707A1 (fr) 2002-01-23 2003-01-21 Acide nucleique codant pour un recepteur couple a la proteine g, et ses utilisations
JP2003561321A JP2005514934A (ja) 2002-01-23 2003-01-21 Gタンパク質共役受容体をコードする核酸、およびその使用
BR0307122-7A BR0307122A (pt) 2002-01-23 2003-01-21 ácido nucléico codificando um receptor acoplado à proteìna g e seus usos
EP03710699A EP1470420A4 (fr) 2002-01-23 2003-01-21 Acide nucleique codant pour un recepteur couple a la proteine g, et ses utilisations
KR10-2004-7011461A KR20040077791A (ko) 2002-01-23 2003-01-21 G-단백질-커플링된 수용체를 암호화하는 핵산 및 이의 용도
NO20043123A NO20043123L (no) 2002-01-23 2004-07-20 En nukleinsyre som koder for en G-proteinkoplet reseptor og anvendelsen av den

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US35100602P 2002-01-23 2002-01-23
US60/351,006 2002-01-23
GBGB0210597.1A GB0210597D0 (en) 2002-01-23 2002-05-09 A nucleic acid encoding a G-protein-coupled receptor,and uses thereof
GB0210597.1 2002-05-09

Publications (2)

Publication Number Publication Date
WO2003061365A2 WO2003061365A2 (fr) 2003-07-31
WO2003061365A3 true WO2003061365A3 (fr) 2003-11-13

Family

ID=27614811

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/001694 Ceased WO2003061365A2 (fr) 2002-01-23 2003-01-21 Acide nucleique codant pour un recepteur couple a la proteine g, et ses utilisations

Country Status (8)

Country Link
EP (1) EP1470420A4 (fr)
JP (1) JP2005514934A (fr)
BR (1) BR0307122A (fr)
CA (1) CA2473707A1 (fr)
MX (1) MXPA04007117A (fr)
NO (1) NO20043123L (fr)
RU (1) RU2004125608A (fr)
WO (1) WO2003061365A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094572B2 (en) 2003-03-14 2006-08-22 Bristol-Myers Squibb Polynucleotide encoding a novel human G-protein coupled receptor variant of HM74, HGPRBMY74

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001036471A2 (fr) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Versions endogenes et non-endogenes de recepteurs couples a la proteine g humaine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1230361A2 (fr) * 1999-10-27 2002-08-14 PHARMACIA & UPJOHN COMPANY Recepteurs couples par des proteines g exprimes dans le cerveau
WO2001094385A2 (fr) * 2000-06-05 2001-12-13 Bayer Aktiengesellschaft Regulation du recepteur couple a la proteine humaine g de type hm74

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001036471A2 (fr) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Versions endogenes et non-endogenes de recepteurs couples a la proteine g humaine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1470420A4 *

Also Published As

Publication number Publication date
EP1470420A4 (fr) 2005-08-24
NO20043123L (no) 2004-07-20
BR0307122A (pt) 2004-12-28
WO2003061365A2 (fr) 2003-07-31
CA2473707A1 (fr) 2003-07-31
MXPA04007117A (es) 2005-02-25
EP1470420A2 (fr) 2004-10-27
JP2005514934A (ja) 2005-05-26
RU2004125608A (ru) 2005-04-20

Similar Documents

Publication Publication Date Title
HUP0203567A2 (hu) APRIL-receptor (BCMA) és alkalmazásai
AU1520195A (en) Use of anti-tnf antibodies as drugs in treating diseases involving elevated interleukin-6 serum levels
WO2002083866A3 (fr) Sequences repetees du gene ca125 et leurs utilisations dans des interventions diagnostiques et therapeutiques
WO2005052000A3 (fr) Anticorps et partenaires de liaison anti-il 20 et procedes d'utilisation dans l'inflammation
EP1470146B8 (fr) Anticorps contre l'antigene muc18
EP2267032A3 (fr) Procédé d'administration de polypeptides thérapeutiques et polypeptides correspondants
PL398596A1 (pl) Preparat zawierający ludzkie przeciwciała do leczenia zaburzeń związanych z TNF-α
WO2004022718A3 (fr) Anticorps monoclonal therapeutique anti-il-1r1 humain
WO2003057837A3 (fr) Procedes d'utilisation d'anticorps anti-muc18
MY139541A (en) Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
WO2004058174A3 (fr) Derives d'acide acetique d'indane et leur utilisation en tant qu'agents pharmaceutiques et intermediaires, et procede de preparation correspondant
WO2001031014A3 (fr) Recepteurs couples par des proteines g exprimes dans le cerveau
AP2002002605A0 (en) Il-8 receptor antagonists
WO2004110385A3 (fr) Modulateurs du recepteur des glucocorticoides et procede associe
WO2003068803A3 (fr) Acide nucleique codant un recepteur couple a la proteine g, et utilisations correspondantes
WO2003061365A3 (fr) Acide nucleique codant pour un recepteur couple a la proteine g, et ses utilisations
AU2003273995A1 (en) Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
AU2002351175A1 (en) Novel human g-protein coupled receptor, hgprbmy31, and variants and methods of use thereof
MXPA04004434A (es) Un acido nucleico que codifica un receptor acoplado a la proteina g y sus usos.
WO2004110993A3 (fr) N-ureidoalkyl-piperidines utilisees comme modulateurs de l'activite des recepteurs de chimiokine
WO2003065045A3 (fr) Diagnostic et traitement de maladies associees au recepteur gpr65
AR037301A1 (es) Un acido nucleico que codifica un receptor acoplado a la proteina g y sus usos
AU2001296263A1 (en) Isolated human g-protein coupled receptors, nucleic acid molecules encoding them, and uses thereof
WO2004083394A3 (fr) Recepteurs humains couples a la proteine g et modulateurs de ceux-ci destines au traitement de troubles inflammatoires
AU2002364149A1 (en) Novel human g-protein coupled receptor, hgprbmy34, and variants and methods of use thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE SI TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2004/05261

Country of ref document: ZA

Ref document number: 200405261

Country of ref document: ZA

WWE Wipo information: entry into national phase

Ref document number: 2003214861

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 163062

Country of ref document: IL

WWE Wipo information: entry into national phase

Ref document number: 2473707

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 1591/CHENP/2004

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 2003561321

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 20038027127

Country of ref document: CN

Ref document number: PA/A/2004/007117

Country of ref document: MX

Ref document number: 1020047011461

Country of ref document: KR

WWE Wipo information: entry into national phase

Ref document number: 2003710699

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2004125608

Country of ref document: RU

WWP Wipo information: published in national office

Ref document number: 2003710699

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 2003710699

Country of ref document: EP