[go: up one dir, main page]

WO2003061365A3 - A nucleic acid encoding a g-protein-coupled receptor, and uses thereof - Google Patents

A nucleic acid encoding a g-protein-coupled receptor, and uses thereof Download PDF

Info

Publication number
WO2003061365A3
WO2003061365A3 PCT/US2003/001694 US0301694W WO03061365A3 WO 2003061365 A3 WO2003061365 A3 WO 2003061365A3 US 0301694 W US0301694 W US 0301694W WO 03061365 A3 WO03061365 A3 WO 03061365A3
Authority
WO
WIPO (PCT)
Prior art keywords
coupled receptor
protein
nucleic acid
acid encoding
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2003/001694
Other languages
French (fr)
Other versions
WO2003061365A2 (en
Inventor
Haifeng Eishingdrelo
Jidong Cai
Anthony Sandrasagra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Aventis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0210597.1A external-priority patent/GB0210597D0/en
Priority to EP03710699A priority Critical patent/EP1470420A4/en
Priority to JP2003561321A priority patent/JP2005514934A/en
Priority to MXPA04007117A priority patent/MXPA04007117A/en
Priority to KR10-2004-7011461A priority patent/KR20040077791A/en
Priority to BR0307122-7A priority patent/BR0307122A/en
Application filed by Aventis Pharmaceuticals Inc filed Critical Aventis Pharmaceuticals Inc
Priority to CA002473707A priority patent/CA2473707A1/en
Publication of WO2003061365A2 publication Critical patent/WO2003061365A2/en
Publication of WO2003061365A3 publication Critical patent/WO2003061365A3/en
Priority to NO20043123A priority patent/NO20043123L/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Provided herein is a novel and useful G-protein coupled receptor that is involved in signal transduction with respect to inflammation and physiological immunological response. Also provided are methods of using the receptor to screen for molecules that may modulate the activity of the receptor. Such molecules may readily have applications in treating a plethora of inflammation and immunologically related diseases and disorders.
PCT/US2003/001694 2002-01-23 2003-01-21 A nucleic acid encoding a g-protein-coupled receptor, and uses thereof Ceased WO2003061365A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CA002473707A CA2473707A1 (en) 2002-01-23 2003-01-21 A nucleic acid encoding a g-protein-coupled receptor, and uses thereof
JP2003561321A JP2005514934A (en) 2002-01-23 2003-01-21 Nucleic acids encoding G protein-coupled receptors and uses thereof
MXPA04007117A MXPA04007117A (en) 2002-01-23 2003-01-21 A nucleic acid encoding a g-protein-coupled receptor, and uses thereof.
KR10-2004-7011461A KR20040077791A (en) 2002-01-23 2003-01-21 A nucleic acid encoding a G-protein-coupled receptor, and uses thereof
BR0307122-7A BR0307122A (en) 2002-01-23 2003-01-21 nucleic acid encoding a protein-coupled receptor and its uses
EP03710699A EP1470420A4 (en) 2002-01-23 2003-01-21 A nucleic acid encoding a g-protein-coupled receptor, and uses thereof
NO20043123A NO20043123L (en) 2002-01-23 2004-07-20 A nucleic acid encoding a G protein-coupled receptor and its use

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US35100602P 2002-01-23 2002-01-23
US60/351,006 2002-01-23
GBGB0210597.1A GB0210597D0 (en) 2002-01-23 2002-05-09 A nucleic acid encoding a G-protein-coupled receptor,and uses thereof
GB0210597.1 2002-05-09

Publications (2)

Publication Number Publication Date
WO2003061365A2 WO2003061365A2 (en) 2003-07-31
WO2003061365A3 true WO2003061365A3 (en) 2003-11-13

Family

ID=27614811

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/001694 Ceased WO2003061365A2 (en) 2002-01-23 2003-01-21 A nucleic acid encoding a g-protein-coupled receptor, and uses thereof

Country Status (8)

Country Link
EP (1) EP1470420A4 (en)
JP (1) JP2005514934A (en)
BR (1) BR0307122A (en)
CA (1) CA2473707A1 (en)
MX (1) MXPA04007117A (en)
NO (1) NO20043123L (en)
RU (1) RU2004125608A (en)
WO (1) WO2003061365A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094572B2 (en) 2003-03-14 2006-08-22 Bristol-Myers Squibb Polynucleotide encoding a novel human G-protein coupled receptor variant of HM74, HGPRBMY74

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1575601A (en) * 1999-10-27 2001-05-08 Pharmacia & Upjohn Company G protein-coupled receptors expressed in brain
AU6604901A (en) * 2000-06-05 2001-12-17 Bayer Aktiengesellschaft Regulation of human hm74-like g protein coupled receptor

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1470420A4 *

Also Published As

Publication number Publication date
EP1470420A4 (en) 2005-08-24
NO20043123L (en) 2004-07-20
WO2003061365A2 (en) 2003-07-31
JP2005514934A (en) 2005-05-26
CA2473707A1 (en) 2003-07-31
RU2004125608A (en) 2005-04-20
BR0307122A (en) 2004-12-28
MXPA04007117A (en) 2005-02-25
EP1470420A2 (en) 2004-10-27

Similar Documents

Publication Publication Date Title
EP1170594A3 (en) Methods for the identification of compounds useful for the treatment of disease states mediated by Prostaglandin D2
HUP0203567A2 (en) April receptor (bcma) and uses thereof
AU1520195A (en) Use of anti-tnf antibodies as drugs in treating diseases involving elevated interleukin-6 serum levels
CA2220461A1 (en) Therapeutic compounds comprised of anti-fc receptor antibodies
WO2002083866A3 (en) Repeat sequences of the ca125 gene and their use for diagnostic and therapeutic interventions
WO2005052000A3 (en) Anti-il-20 antibodies and binding partners and methods of using in inflammation
PL398596A1 (en) Preparation containing human antibodies for the treatment of disorders associated with TNF-α
WO2004022718A3 (en) Therapeutic human anti-il-1r1 monoclonal antibody
MY139541A (en) Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
DE60234616D1 (en) SUBSTITUTED PIPERIDINES WITH SELECTIVE BINDING ABILITY TO HISTAMINE H3 RECEPTORS
WO2004058174A3 (en) Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
WO2001031014A3 (en) G protein-coupled receptors expressed in human brain
AP2002002605A0 (en) Il-8 receptor antagonists
WO2004110385A3 (en) Modulators of the glucocorticoid receptor and method
WO2003068803A3 (en) A nucleic acid encoding a g-protein-coupled receptor, and uses thereof
WO2003061365A3 (en) A nucleic acid encoding a g-protein-coupled receptor, and uses thereof
AU2002351175A1 (en) Novel human g-protein coupled receptor, hgprbmy31, and variants and methods of use thereof
WO2001037874A3 (en) Treatment of psoriasis by using an antibody to tnf alpha
MXPA04004434A (en) A nucleic acid encoding a g-protein-coupled receptor, and uses thereof.
WO2001089549A3 (en) Therapeutic uses of il-1 receptor antagonist
WO2003065045A3 (en) Diagnostics and therapeutics for diseases associated with the gpr65 receptor
AR037301A1 (en) A NUCLEIC ACID CODING A RECEPTOR COUPLED TO PROTEIN G AND ITS USES
AU2001296263A1 (en) Isolated human g-protein coupled receptors, nucleic acid molecules encoding them, and uses thereof
AU2002364149A1 (en) Novel human g-protein coupled receptor, hgprbmy34, and variants and methods of use thereof
WO2003099779A3 (en) Hemipteran muscarinic receptor

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE SI TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2004/05261

Country of ref document: ZA

Ref document number: 200405261

Country of ref document: ZA

WWE Wipo information: entry into national phase

Ref document number: 2003214861

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 163062

Country of ref document: IL

WWE Wipo information: entry into national phase

Ref document number: 2473707

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 1591/CHENP/2004

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 2003561321

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 20038027127

Country of ref document: CN

Ref document number: PA/A/2004/007117

Country of ref document: MX

Ref document number: 1020047011461

Country of ref document: KR

WWE Wipo information: entry into national phase

Ref document number: 2003710699

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2004125608

Country of ref document: RU

WWP Wipo information: published in national office

Ref document number: 2003710699

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 2003710699

Country of ref document: EP