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WO2002099084A3 - Composite binding polypeptides - Google Patents

Composite binding polypeptides Download PDF

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Publication number
WO2002099084A3
WO2002099084A3 PCT/US2002/022272 US0222272W WO02099084A3 WO 2002099084 A3 WO2002099084 A3 WO 2002099084A3 US 0222272 W US0222272 W US 0222272W WO 02099084 A3 WO02099084 A3 WO 02099084A3
Authority
WO
WIPO (PCT)
Prior art keywords
binding polypeptides
composite binding
polypeptides
composite
constructed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/022272
Other languages
French (fr)
Other versions
WO2002099084A2 (en
WO2002099084A9 (en
Inventor
Michael Moore
Armin Sepp
Mark Isalan
Yen Choo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gendaq Ltd
Original Assignee
Gendaq Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gendaq Ltd filed Critical Gendaq Ltd
Priority to AU2002322477A priority Critical patent/AU2002322477A1/en
Priority to US10/474,282 priority patent/US20040197892A1/en
Publication of WO2002099084A2 publication Critical patent/WO2002099084A2/en
Anticipated expiration legal-status Critical
Publication of WO2002099084A3 publication Critical patent/WO2002099084A3/en
Publication of WO2002099084A9 publication Critical patent/WO2002099084A9/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Disclosed herein are polypeptides with novel DNA binding specificities, constructed from combinations of zinc fingers, and methods for their preparation and use.
PCT/US2002/022272 2001-04-04 2002-04-04 Composite binding polypeptides Ceased WO2002099084A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2002322477A AU2002322477A1 (en) 2001-04-04 2002-04-04 Composite binding polypeptides
US10/474,282 US20040197892A1 (en) 2001-04-04 2002-04-04 Composition binding polypeptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0108491.2 2001-04-04
GB0108491A GB0108491D0 (en) 2001-04-04 2001-04-04 Engineering zinc fingers

Publications (3)

Publication Number Publication Date
WO2002099084A2 WO2002099084A2 (en) 2002-12-12
WO2002099084A3 true WO2002099084A3 (en) 2003-10-23
WO2002099084A9 WO2002099084A9 (en) 2004-12-16

Family

ID=9912259

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/022272 Ceased WO2002099084A2 (en) 2001-04-04 2002-04-04 Composite binding polypeptides

Country Status (3)

Country Link
AU (1) AU2002322477A1 (en)
GB (1) GB0108491D0 (en)
WO (1) WO2002099084A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8685737B2 (en) 2011-04-27 2014-04-01 Amyris, Inc. Methods for genomic modification

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