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WO2002064761A3 - Regulation of human long chain polyunsaturated fatty acid elongation enzyme-like protein - Google Patents

Regulation of human long chain polyunsaturated fatty acid elongation enzyme-like protein Download PDF

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Publication number
WO2002064761A3
WO2002064761A3 PCT/EP2002/001260 EP0201260W WO02064761A3 WO 2002064761 A3 WO2002064761 A3 WO 2002064761A3 EP 0201260 W EP0201260 W EP 0201260W WO 02064761 A3 WO02064761 A3 WO 02064761A3
Authority
WO
WIPO (PCT)
Prior art keywords
fatty acid
long chain
polyunsaturated fatty
chain polyunsaturated
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2002/001260
Other languages
French (fr)
Other versions
WO2002064761A2 (en
Inventor
Zhimin Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to AU2002231779A priority Critical patent/AU2002231779A1/en
Publication of WO2002064761A2 publication Critical patent/WO2002064761A2/en
Publication of WO2002064761A3 publication Critical patent/WO2002064761A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Reagents that regulate human long chain polyunsaturated fatty acid elongation enzyme-like protein and reagents which bind to human long chain polyunsaturated fatty acid elongation enzyme-like gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer, diabetes, CNS disorder, metabolic disease, asthma or COPD.
PCT/EP2002/001260 2001-02-09 2002-02-07 Regulation of human long chain polyunsaturated fatty acid elongation enzyme-like protein Ceased WO2002064761A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002231779A AU2002231779A1 (en) 2001-02-09 2002-02-07 Regulation of human long chain polyunsaturated fatty acid elongation enzyme-like protein

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US26741501P 2001-02-09 2001-02-09
US60/267,415 2001-02-09
US33144901P 2001-11-16 2001-11-16
US60/331,449 2001-11-16
US33494801P 2001-12-04 2001-12-04
US60/334,948 2001-12-04

Publications (2)

Publication Number Publication Date
WO2002064761A2 WO2002064761A2 (en) 2002-08-22
WO2002064761A3 true WO2002064761A3 (en) 2003-05-01

Family

ID=27401965

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/001260 Ceased WO2002064761A2 (en) 2001-02-09 2002-02-07 Regulation of human long chain polyunsaturated fatty acid elongation enzyme-like protein

Country Status (2)

Country Link
AU (1) AU2002231779A1 (en)
WO (1) WO2002064761A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009502114A (en) * 2005-07-27 2009-01-29 オンコセラピー・サイエンス株式会社 Genes and polypeptides related to prostate cancer
TW201032820A (en) * 2008-12-16 2010-09-16 Oncotherapy Science Inc ELOVL7 epitope peptides and vaccines containing the same

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012720A2 (en) * 1998-09-02 2000-03-09 Abbott Laboratories Elongase genes and uses thereof
WO2000070945A2 (en) * 1999-05-20 2000-11-30 Karolinska Innovations Ab Fatty acid elongation genes and uses thereof
WO2001004636A1 (en) * 1999-07-12 2001-01-18 Ohio University Mammalian cells expressing desaturases and elongases
WO2002044320A2 (en) * 2000-11-29 2002-06-06 Xenon Genetics Inc. Human elongase genes and uses thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012720A2 (en) * 1998-09-02 2000-03-09 Abbott Laboratories Elongase genes and uses thereof
WO2000070945A2 (en) * 1999-05-20 2000-11-30 Karolinska Innovations Ab Fatty acid elongation genes and uses thereof
WO2001004636A1 (en) * 1999-07-12 2001-01-18 Ohio University Mammalian cells expressing desaturases and elongases
WO2002044320A2 (en) * 2000-11-29 2002-06-06 Xenon Genetics Inc. Human elongase genes and uses thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 27 January 2000 (2000-01-27), XP002228622, retrieved from EBI Database accession no. AL137506 *
LEONARD AMANDA E ET AL: "Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids", BIOCHEMICAL JOURNAL, PORTLAND PRESS, LONDON, GB, vol. 350, no. 3, 2000, pages 765 - 770, XP002208697, ISSN: 0264-6021 *
OH ET AL: "ELO2 and ELO3, homologs of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 272, no. 28, 11 July 1997 (1997-07-11), pages 17376 - 17384, XP002119019, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
WO2002064761A2 (en) 2002-08-22
AU2002231779A1 (en) 2002-08-28

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