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WO2001013969A1 - Dispositif et procede servant a fabriquer une moelle artificielle poreuse en titane-nickel au moyen d'une technique de synthese par rotation a chaud - Google Patents

Dispositif et procede servant a fabriquer une moelle artificielle poreuse en titane-nickel au moyen d'une technique de synthese par rotation a chaud Download PDF

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Publication number
WO2001013969A1
WO2001013969A1 PCT/KR2000/000938 KR0000938W WO0113969A1 WO 2001013969 A1 WO2001013969 A1 WO 2001013969A1 KR 0000938 W KR0000938 W KR 0000938W WO 0113969 A1 WO0113969 A1 WO 0113969A1
Authority
WO
WIPO (PCT)
Prior art keywords
titanium
nickel
sample
medulla
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2000/000938
Other languages
English (en)
Inventor
Ki Suk Han
Ji Soon Kim
Seung Baik Kang
Tae Hyun Nam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHINHAN MACHINERY CO Ltd
Bio Smart Ltd
Original Assignee
SHINHAN MACHINERY CO Ltd
Bio Smart Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHINHAN MACHINERY CO Ltd, Bio Smart Ltd filed Critical SHINHAN MACHINERY CO Ltd
Priority to AU67364/00A priority Critical patent/AU6736400A/en
Publication of WO2001013969A1 publication Critical patent/WO2001013969A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F3/00—Manufacture of workpieces or articles from metallic powder characterised by the manner of compacting or sintering; Apparatus specially adapted therefor ; Presses and furnaces
    • B22F3/23—Manufacture of workpieces or articles from metallic powder characterised by the manner of compacting or sintering; Apparatus specially adapted therefor ; Presses and furnaces involving a self-propagating high-temperature synthesis or reaction sintering step
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A61L27/06—Titanium or titanium alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006—Properties of materials and coating materials
    • A61F2002/30092—Properties of materials and coating materials using shape memory or superelastic materials, e.g. nitinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00011—Metals or alloys
    • A61F2310/00023—Titanium or titanium-based alloys, e.g. Ti-Ni alloys

Definitions

  • the present invention relates to an apparatus and method for manufacturing an artificial porous titanium- nickel medulla by using a hot rotational synthesis method, and more particularly to an apparatus and method for manufacturing an artificial porous titanium nickel medulla by using a hot rotational synthesis method, in which a porous structure is controlled to obtain mechanical qualities required for an implant material at a site of a shattered medulla which absolutely requires initial stability, thereby enhancing osteoconduction effect and bone ingrowth, and a newly grown medulla is created after implant and then its material qualities are controlled to be similar to a human medulla, thereby obtaining biocompatibilty.
  • medulla grafting In general, after lesion of a patient having a shattered medulla, such as a joint defect, trauma, and medulla tumor, is excised, automedulla grafting, isomedulla grafting or heteromedulla grafting is operated to protect legs and arms of the patient.
  • medulla grafting such as automedulla grafting, isomedulla grafting and heteromedulla grafting has several problems. That is, the medulla grafting is subject to various limitations as to whether bio- compatibility exists or not depending on both the site of the shattered medulla and body qualities of the patient.
  • an artificial medulla for grafting on a site of a shattered medulla is manufactured based on powder metallurgy method.
  • the artificial medulla is manufactured in such a manner that the site of the shattered medulla of a patient is incised and then metal or ceramics powder is compressed and sintered to protect legs and arms of the patient without subjecting the patient to factors such as the site of the shattered medulla and body qualities.
  • the power metallurgy method has several problems. That is, the power metallurgy method does not permit a porous structure having mechanical qualities suitable for the site of the shattered medulla of the patient to be manufactured. Also, the artificial medulla is not controlled to be similar to an actual medulla of a human body, thereby causing some problems in biocompatibility . Disclosure Of Invention
  • an object of the present invention is to solve at least the problems and disadvantages of the prior art.
  • Another object of the present invention is to provide an apparatus and method for manufacturing an artificial porous titanium nickel medulla by using a hot rotational synthesis method, in which a porous structure is controlled to obtain mechanical qualities required for an implant material at a site of a shattered medulla which absolutely requires initial stability, thereby enhancing osteoconduction effect and bone ingrowth.
  • object of the present invention is to provide an apparatus and method for manufacturing an artificial porous titanium nickel medulla by using a hot rotational synthesis method, in which a newly grown medulla is created after implant and the its material qualities are controlled to be similar to a human medulla, thereby obtaining biocompatibilty.
  • a method for manufacturing an artificial porous titanium nickel medulla by using a hot rotational synthesis method includes the steps of drying raw powders of titanium and nickel under the vacuum state to remove moisture and surface absorption materials, thereby minimizing an amount of gas generated during synthesis reaction, dry-mixing the raw powders dried during the drying step with each other at a ratio of about 1:1 in atomic amount to manufacture mixed powders having uniform compositions, molding the mixed powders within a cylindrical quartz tube with compression or without pressure depending on a desired porosity and pore size, reacting the mixed powders molded in the molding step in a reaction furnace by a hot rotational synthesis method, cooling titanium-nickel products reacted in the reacting step using a reservoir for a cooling liquid, and removing impurities on a surface of the cooled Titanium-nickel products to process the titanium-nickel products in a desired shape.
  • Fig. 1 is a view showing the manufacturing steps of an artificial medulla according to the present invention.
  • Fig. 2 is a view showing an apparatus for manufacturing an artificial medulla according to the present invention. Best Mode for Carrying out the Invention
  • a method for manufacturing an artificial porous titanium nickel medulla by using a hot rotational synthesis method includes the steps of drying raw powders of titanium and nickel under the vacuum state to remove moisture and surface absorption materials, thereby minimizing an amount of gas generated during synthesis reaction, dry- mixing the raw powders dried during the drying step with each other at a ratio of about 1:1 in atomic amount to manufacture mixed powders having uniform compositions, molding the mixed powders within a cylindrical quartz tube with compression or without pressure depending on a desired porosity and pore size, reacting the mixed powders molded in the molding step in a reaction furnace by a hot rotational synthesis method, cooling titanium- nickel products reacted in the reacting step using a reservoir for a cooling liquid, and removing impurities on a surface of the cooled titanium-nickel products to process the titanium-nickel products in a desired shape.
  • the raw powders of titanium and nickel are dried for 8 hours or more at a temperature between 60°C and 70°C under the vacuum state.
  • the dried powders are dry-mixed with each other by a ball mill for 10 ⁇ 12 hours .
  • a vessel such as glass material is used to prevent the mixed powders from being contaminated.
  • a grinder such as a steel mill is not used.
  • a molding body molded within the quartz tube has a diameter of 20mm or greater to avoid instability (extinguishment) of the ignition wave due to heat loss and to obtain adiabatic reaction conditions.
  • the molding body has a porosity of 30 ⁇ 70%. If porosity is too low, heat loss caused by heat transfer during ignition reaction increases. This could prevent the ignition wave from being propagated. That is, it is likely that the ignition wave is extinguished. On the other hand, if porosity is too high, intensity becomes low so as not to be handled in the manufacturing steps.
  • an apparatus for manufacturing an artificial porous titanium nickel medulla by using a hot rotational synthesis method includes an inert gas receptacle 10 for containing an inert gas of which amount is controlled by a gas flow controller 11, a tubular reactor 20 to which the inert gas contained in the inert gas receptacle 10 is supplied, a titanium-nickel sample 50 mixed in a quartz tube 40 which is provided in the tubular reactor 20, and a reaction furnace 30 for allowing the tubular reactor 20 provided with the sample 50 to obtain sufficient adiabatic reaction.
  • the gas flow controller 11 is mounted in the inert gas receptacle 10 and controls inner pressure of the tubular reactor 20 at 1 ⁇ 2 Torr.
  • the sample is preheated within the tubular reactor 22 at a temperature of 250°C ⁇ 550°C to obtain sufficient adiabatic reaction because the sample has a low adiabatic temperature during rotational synthesis reaction of titanium and nickel. If the sample 50 preheated within the tubular reactor 20 reaches a predetermined temperature, the sample 50 is ignited by the igniter 81. That is, the sample 50 acts as a mixed powder molding body ignited by the igniter 80.
  • an end portion of the sample 50 may partially be removed.
  • a mixed powder of titanium and boron (B) may be filled in the portion where the sample 50 is partially removed, so as to be used as an auxiliary means such as a chemical furnace.
  • the present invention as described above, two or more elements are reacted to form a compound, and a powder is manufactured based on heat generated when forming the compound.
  • the artificial medulla is manufactured by a hot rotational synthesis method.
  • the hot rotational synthesis method when manufacturing a metal compound, impurities mixed with the raw powders in the synthesis reaction of high temperature are removed. Thus, a compound of high purity can be obtained.
  • the method for manufacturing an artificial porous titanium nickel medulla based on the hot rotational synthesis method includes the steps of drying raw powders of titanium and nickel under the vacuum state to remove moisture and surface absorption materials, thereby minimizing an amount of gas generated during synthesis reaction, dry-mixing the raw powders dried during the drying step with each other at a ratio of about 1:1 in atomic amount to manufacture mixed powders having uniform compositions, molding the mixed powders within a cylindrical quartz tube with compression or without pressure depending on a desired porosity and pore size, reacting the mixed powders molded in the molding step in a reaction furnace by a hot rotational synthesis method, cooling titanium-nickel products reacted in the reacting step using a reservoir for a cooling liquid, and removing impurities on a surface of the cooled titanium-nickel products to process the titanium-nickel products in a desired shape.
  • the inert gas contained in the inert gas receptacle is controlled and supplied by the gas flow controller 11 to maintain the inner pressure of the tubular reactor 20 provided with titanium and nickel powders at 1 ⁇ 2 Torr.
  • the reaction furnace controlling thermo couple 71 senses an inner temperature of the tubular reactor 20. If the inner temperature of the tubular reactor 20 is 250°C ⁇ 550°C or below, the temperature controller is operated to supply insufficient heat from the heating element 31 provided in the reaction furnace 30. If the inner temperature of the tubular reactor 20 reaches 250°C ⁇ 550°C by means of the heating element 31, the sample 50 in the quartz tube 40 is ignited by the igniter 81 which receives high power from the transformer 80.
  • the ignition wave is propagated into the mixed powder molding body to complete reaction.
  • the tubular reactor 20 is extracted from the reaction furnace 30.
  • the mixed powder molding body is then cooled by a reservoir for a cooling liquid (not shown) .
  • Surface impurities of the cooled mixed powder molding body i.e., cooled titanium-nickel products, are removed by grinding or turning so that the cooled titanium-nickel products are processed by the discharge processing method in a desired shape. It is noted that the surface impurities are also pickled with a mixed solution of distilled water of hydrofluoric acid and nitric acid, so as to be removed.
  • the aforementioned apparatus and method for manufacturing an artificial porous titanium nickel medulla by using a hot rotational synthesis method has the following advantages.
  • a porous structure is controlled to obtain mechanical qualities required for an implant material at a site of a shattered medulla which absolutely requires initial stability, thereby enhancing osteoconduction effect and bone ingrowth, and a newly grown medulla is created after implant and then its material qualities are controlled to be similar to a human medulla, thereby obtaining biocompatibilty.
  • biocompatibility exists or not depending on both the site of the shattered medulla and body qualities of the patient .

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Powder Metallurgy (AREA)
  • Prostheses (AREA)

Abstract

Dispositif et procédé servant à fabriquer une moelle artificielleporeuse en titane-nickel au moyen d'une technique de synthèse parrotation à chaud. Ce procédé consiste à sécher des poudres brutesde titane et de nickel sous vide, à mélanger ces poudres brutesséchées selon un rapport de 1 :1, à mouler les poudres mélangées dans un tube de quartz cylindrique avec ou sans compression, à effectuer la réaction des poudres mélangées et moulées dans un four de réaction au moyen d'une technique de synthèse par rotation à chaud, à refroidir les produits réactionnels de titane-nickel au moyen d'un réservoir contenant un liquide de refroidissement et à supprimer les impuretés de surface de ces produits de titane-nickel afin de les façonner dans la forme désirée.
PCT/KR2000/000938 1999-08-23 2000-08-22 Dispositif et procede servant a fabriquer une moelle artificielle poreuse en titane-nickel au moyen d'une technique de synthese par rotation a chaud Ceased WO2001013969A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU67364/00A AU6736400A (en) 1999-08-23 2000-08-22 Apparatus and method for manufacturing an artificial porous titanium nickel medulla by using a hot rotational synthesis method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1999/34961 1999-08-23
KR1019990034961A KR100320804B1 (ko) 1999-08-23 1999-08-23 고온자전합성법에 의한 다공성 티탄니켈 인공골 제조방법 및그 장치

Publications (1)

Publication Number Publication Date
WO2001013969A1 true WO2001013969A1 (fr) 2001-03-01

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Country Status (3)

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KR (1) KR100320804B1 (fr)
AU (1) AU6736400A (fr)
WO (1) WO2001013969A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001087370A1 (fr) * 2000-05-19 2001-11-22 Vidam Technology Ltd. Structure de nickel-titane poreuse utilisee comme support pour des cellules vivantes
EP1287796A1 (fr) 2001-09-04 2003-03-05 Biorthex Inc. Dispositif de fusion intervertébrale
FR2834999A1 (fr) * 2002-01-21 2003-07-25 Delachaux Sa Procede de fabrication d'elements metalliques de purete elevee
WO2005014072A1 (fr) * 2003-08-08 2005-02-17 Biorthex Inc. Matiere ti-ni poreuse biocompatible
CN100389915C (zh) * 2006-03-21 2008-05-28 北京科技大学 一种高孔隙度镍钛基形状记忆合金的凝胶注模成型方法
CN102329978A (zh) * 2011-10-09 2012-01-25 上海大学 利用非固溶合金腐蚀烧结制备多孔材料的方法
RU2798496C1 (ru) * 2022-10-21 2023-06-23 Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский Томский государственный университет" Способ получения пористого сплава на основе никелида титана

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010069275A (ko) * 2001-02-26 2001-07-25 최재복 뽕잎, 누에, 동충하초가 함유된 기능성 선식의 조성 및제조방법
RU2320741C2 (ru) * 2006-02-06 2008-03-27 Виктор Эдуардович Гюнтер Пористый сплав на основе никелида титана и способ его получения
RU2394112C2 (ru) * 2008-09-17 2010-07-10 Виктор Эдуардович Гюнтер Способ получения пористого никелида титана

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JPS5250909A (en) * 1975-10-21 1977-04-23 Natl Res Inst For Metals Process for producing porous ti-ni, ti-co alloy
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WO1999034845A1 (fr) * 1997-12-31 1999-07-15 Biorthex Inc. Article poreux en alliage nickel-titane

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SU662270A1 (ru) * 1977-07-25 1979-05-15 Сибирский Физико-Технический Институт Им.В.Д.Кузнецова При Томском Ордена Трудового Красного Знамени Государственном Университете Им.В.В.Куйбышева Способ получени материалов на основе никелида титана
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JPH03295562A (ja) * 1990-04-13 1991-12-26 Daido Steel Co Ltd 生体用形状記憶合金
DE4210801A1 (de) * 1992-04-01 1992-11-05 Rossar Ingeneering Gbr Ges Fue Verfahren zur herstellung einer nickel-titanum (niti)-legierung mit dem effekt der formenwiederherstellung zur herstellung von reparaturteilen und prothesen fuer den menschlichen koerper
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PATENT ABSTRACTS OF JAPAN *

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001087370A1 (fr) * 2000-05-19 2001-11-22 Vidam Technology Ltd. Structure de nickel-titane poreuse utilisee comme support pour des cellules vivantes
EP1287796A1 (fr) 2001-09-04 2003-03-05 Biorthex Inc. Dispositif de fusion intervertébrale
FR2834999A1 (fr) * 2002-01-21 2003-07-25 Delachaux Sa Procede de fabrication d'elements metalliques de purete elevee
WO2003062479A1 (fr) * 2002-01-21 2003-07-31 Delachaux S.A. Procede de fabrication d'elements metalliques de purete elevee tel que le chrome
RU2306349C2 (ru) * 2002-01-21 2007-09-20 Делашо С.А. Способ получения металлических гранул высокой чистоты, таких как гранулы хрома
US7361205B2 (en) 2002-01-21 2008-04-22 Delachaux S.A. Method for production of metallic elements of high purity such as chromes
WO2005014072A1 (fr) * 2003-08-08 2005-02-17 Biorthex Inc. Matiere ti-ni poreuse biocompatible
US7604870B2 (en) 2003-08-08 2009-10-20 Nitinol Devices And Components, Inc. Biocompatible porous Ti-Ni material
CN100389915C (zh) * 2006-03-21 2008-05-28 北京科技大学 一种高孔隙度镍钛基形状记忆合金的凝胶注模成型方法
CN102329978A (zh) * 2011-10-09 2012-01-25 上海大学 利用非固溶合金腐蚀烧结制备多孔材料的方法
RU2798496C1 (ru) * 2022-10-21 2023-06-23 Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский Томский государственный университет" Способ получения пористого сплава на основе никелида титана

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