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WO1997014783B1 - Reparation osseuse par modification tissulaire faisant appel a des cellules periostiques cultivees - Google Patents

Reparation osseuse par modification tissulaire faisant appel a des cellules periostiques cultivees

Info

Publication number
WO1997014783B1
WO1997014783B1 PCT/US1996/016664 US9616664W WO9714783B1 WO 1997014783 B1 WO1997014783 B1 WO 1997014783B1 US 9616664 W US9616664 W US 9616664W WO 9714783 B1 WO9714783 B1 WO 9714783B1
Authority
WO
WIPO (PCT)
Prior art keywords
cells
matrix
composition
periosteal
bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1996/016664
Other languages
English (en)
Other versions
WO1997014783A1 (fr
Filing date
Publication date
Priority claimed from US08/545,988 external-priority patent/US5700289A/en
Application filed filed Critical
Priority to AU74515/96A priority Critical patent/AU7451596A/en
Priority to EP96936643A priority patent/EP0862617A1/fr
Publication of WO1997014783A1 publication Critical patent/WO1997014783A1/fr
Publication of WO1997014783B1 publication Critical patent/WO1997014783B1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Abstract

Il a été démontré que des cellules périostiques mises en culture avaient un phénotype ostéoblastique, avec production d'ostéocalcine et de mucopolysaccharides. Il a également été démontré qu'après avoir été ensemencées dans des implants polymères, elles réparaient des lacunes crâniennes d'une taille critique, et cette réparation a été confirmée par histologie, dosages biochimiques et radiodensitométrie.
PCT/US1996/016664 1995-10-20 1996-10-17 Reparation osseuse par modification tissulaire faisant appel a des cellules periostiques cultivees Ceased WO1997014783A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU74515/96A AU7451596A (en) 1995-10-20 1996-10-17 Tissue-engineered bone repair using cultured periosteal cells
EP96936643A EP0862617A1 (fr) 1995-10-20 1996-10-17 Reparation osseuse par modification tissulaire faisant appel a des cellules periostiques cultivees

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US545,988 1990-06-28
US08/545,988 US5700289A (en) 1995-10-20 1995-10-20 Tissue-engineered bone repair using cultured periosteal cells

Publications (2)

Publication Number Publication Date
WO1997014783A1 WO1997014783A1 (fr) 1997-04-24
WO1997014783B1 true WO1997014783B1 (fr) 1997-05-22

Family

ID=24178377

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/016664 Ceased WO1997014783A1 (fr) 1995-10-20 1996-10-17 Reparation osseuse par modification tissulaire faisant appel a des cellules periostiques cultivees

Country Status (4)

Country Link
US (1) US5700289A (fr)
EP (1) EP0862617A1 (fr)
AU (1) AU7451596A (fr)
WO (1) WO1997014783A1 (fr)

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