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WO1996039390B1 - Derives de benzimidazole inhibiteurs de la proliferation des cellules musculaires lisses - Google Patents

Derives de benzimidazole inhibiteurs de la proliferation des cellules musculaires lisses

Info

Publication number
WO1996039390B1
WO1996039390B1 PCT/US1996/008353 US9608353W WO9639390B1 WO 1996039390 B1 WO1996039390 B1 WO 1996039390B1 US 9608353 W US9608353 W US 9608353W WO 9639390 B1 WO9639390 B1 WO 9639390B1
Authority
WO
WIPO (PCT)
Prior art keywords
carbon atoms
alkyl
phenyl
hydrogen
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1996/008353
Other languages
English (en)
Other versions
WO1996039390A1 (fr
Filing date
Publication date
Priority claimed from US08/468,482 external-priority patent/US6288100B1/en
Application filed filed Critical
Priority to NZ309490A priority Critical patent/NZ309490A/en
Priority to JP9500980A priority patent/JPH11506749A/ja
Priority to AU59673/96A priority patent/AU713043B2/en
Priority to EP96916965A priority patent/EP0830343A1/fr
Priority to BR9609365A priority patent/BR9609365A/pt
Publication of WO1996039390A1 publication Critical patent/WO1996039390A1/fr
Publication of WO1996039390B1 publication Critical patent/WO1996039390B1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Abstract

Composés et sels pharmaceutiquement acceptables de composés de formule (I) ou (II), dans lesquelles R est alkyle, phényle ou phényle substitué, R2 est hydrogène, halogène, alcoxy ou alkyle, R1 est hydrogène, alkyle, aryle, arylalkyle ou benzyle substitué. Ces substances sont utiles comme inhibiteurs de la prolifération des cellules musculaires lisses.
PCT/US1996/008353 1995-06-06 1996-06-03 Derives de benzimidazole inhibiteurs de la proliferation des cellules musculaires lisses Ceased WO1996039390A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
NZ309490A NZ309490A (en) 1995-06-06 1996-06-03 Benzimidazole derivatives as inhibitors of smooth muscle cell proliferation
JP9500980A JPH11506749A (ja) 1995-06-06 1996-06-03 平滑筋細胞増殖の阻害薬としてのベンゾイミダゾール誘導体
AU59673/96A AU713043B2 (en) 1995-06-06 1996-06-03 Benzimidazole derivatives as inhibitors of smooth muscle cell proliferation
EP96916965A EP0830343A1 (fr) 1995-06-06 1996-06-03 Derives de benzimidazole inhibiteurs de la proliferation des cellules musculaires lisses
BR9609365A BR9609365A (pt) 1995-06-06 1996-06-03 Derivados de benzimidazol como inibidores de proliferação de células de músculo liso

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/468,482 US6288100B1 (en) 1995-06-06 1995-06-06 Benzimidazole derivatives
US08/468,482 1995-06-06

Publications (2)

Publication Number Publication Date
WO1996039390A1 WO1996039390A1 (fr) 1996-12-12
WO1996039390B1 true WO1996039390B1 (fr) 1997-01-09

Family

ID=23859998

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/008353 Ceased WO1996039390A1 (fr) 1995-06-06 1996-06-03 Derives de benzimidazole inhibiteurs de la proliferation des cellules musculaires lisses

Country Status (13)

Country Link
US (1) US6288100B1 (fr)
EP (1) EP0830343A1 (fr)
JP (1) JPH11506749A (fr)
KR (1) KR19990022372A (fr)
CN (1) CN1192205A (fr)
AR (1) AR002748A1 (fr)
AU (1) AU713043B2 (fr)
BR (1) BR9609365A (fr)
CA (1) CA2223393A1 (fr)
IL (1) IL118384A0 (fr)
NZ (1) NZ309490A (fr)
WO (1) WO1996039390A1 (fr)
ZA (1) ZA964692B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5188988B2 (ja) 2006-02-10 2013-04-24 トランステック ファーマ，インコーポレイティド ベンゾアゾール誘導体、組成物、及びオーロラキナーゼ阻害剤としての使用方法
WO2010051085A1 (fr) * 2008-10-30 2010-05-06 Oncotherapy Science, Inc. Dérivés de 7-hydroxy-benzo-imidazole-4-yl-méthanone et inhibiteurs de pbk les contenant

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1062950A (en) * 1963-12-31 1967-03-22 Gevaert Photo Prod Nv Trimethine dyes
GR78209B (fr) * 1982-04-15 1984-09-26 May & Baker Ltd
DE3505609A1 (de) 1985-02-19 1986-08-21 Merck Patent Gmbh, 6100 Darmstadt Benzimidazolyl-pyridazinone
HU193951B (en) 1985-03-11 1987-12-28 Richter Gedeon Vegyeszet Process for producing new sulfur-containing 5-substituted benzimidazol derivatives and pharmaceutical compositions containing them
NZ221729A (en) * 1986-09-15 1989-07-27 Janssen Pharmaceutica Nv Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions
US4859684A (en) * 1986-09-15 1989-08-22 Janssen Pharmaceutica N.V. (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives and use thereof in treating androgen dependent disorders
US5200422A (en) 1990-09-24 1993-04-06 Neurosearch A/S Benzimidazole derivatives, their preparation and use
DE4212748A1 (de) 1992-04-16 1993-10-21 Thomae Gmbh Dr K Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
JP2759228B2 (ja) 1992-05-21 1998-05-28 株式会社大塚製薬工場 ホスホン酸ジエステル誘導体
US5387600A (en) 1992-07-30 1995-02-07 Fuji Photo Film Co., Ltd. Treating arteriosclerosis using benzimidazole compositions

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