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WO1996019205B1 - Systeme de liberation transdermique avec opercule adhesif et rondelle pelable - Google Patents

Systeme de liberation transdermique avec opercule adhesif et rondelle pelable

Info

Publication number
WO1996019205B1
WO1996019205B1 PCT/US1995/016498 US9516498W WO9619205B1 WO 1996019205 B1 WO1996019205 B1 WO 1996019205B1 US 9516498 W US9516498 W US 9516498W WO 9619205 B1 WO9619205 B1 WO 9619205B1
Authority
WO
WIPO (PCT)
Prior art keywords
peel seal
backing layer
active agent
seal disc
adhesive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1995/016498
Other languages
English (en)
Other versions
WO1996019205A1 (fr
Filing date
Publication date
Application filed filed Critical
Priority to EP95943869A priority Critical patent/EP0799029A1/fr
Priority to AU45233/96A priority patent/AU695170B2/en
Priority to JP8519931A priority patent/JPH10511353A/ja
Publication of WO1996019205A1 publication Critical patent/WO1996019205A1/fr
Publication of WO1996019205B1 publication Critical patent/WO1996019205B1/fr
Priority to MXPA/A/1997/004291A priority patent/MXPA97004291A/xx
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Abstract

Dispositif (10) conçu pour appliquer une substance active sur la peau ou les muqueuses d'un individu, qui est constitué des parties suivantes: un composite laminaire d'un opercule adhésif (26), une couche dorsale (14) sur laquelle repose la partie centrale de l'opercule, une membrane active (16) perméable à la substance administrée, la couche dorsale et la membrane qui délimitent un réceptacle (12) contenant la formulation de la substance active, une rondelle pelable (20) sur laquelle repose la membrane active perméable à la substance, un joint à thermoscellage (22) sur le pourtour de la rondelle pelable. La membrane active perméable à la substance, la couche dorsale et un revêtement intérieur amovible (24) de diffusion sont à la base de la partie exposée de l'opercule et de la rondelle pelable. Le revêtement adhésif est placé au-dessus et en bordure de la trajectoire de la substance active vers la peau et les muqueuses et il est protégé de la dégradation des composants du réceptacle par plusieurs joints à thermoscellage. La rondelle pelable sert de protection contre la diffusion de la substance active contenue dans le réceptacle et le revêtement intérieur de diffusion empêche la partie adhésive d'être exposée à l'environnement extérieur avant toute utilisation.
PCT/US1995/016498 1994-12-21 1995-12-08 Systeme de liberation transdermique avec opercule adhesif et rondelle pelable Ceased WO1996019205A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP95943869A EP0799029A1 (fr) 1994-12-21 1995-12-08 Systeme de liberation transdermique avec opercule adhesif et rondelle pelable
AU45233/96A AU695170B2 (en) 1994-12-21 1995-12-08 Transdermal delivery system with adhesive overlay and peel seal disc
JP8519931A JPH10511353A (ja) 1994-12-21 1995-12-08 接着剤オーバーレイおよび剥離性シールディスクを用いた経皮送達システム
MXPA/A/1997/004291A MXPA97004291A (en) 1994-12-21 1997-06-10 System of release transdermica conrecubrimiento adhesivo and disco de selladodesprendi

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36180094A 1994-12-21 1994-12-21
US08/361,800 1994-12-21

Publications (2)

Publication Number Publication Date
WO1996019205A1 WO1996019205A1 (fr) 1996-06-27
WO1996019205B1 true WO1996019205B1 (fr) 1996-08-08

Family

ID=23423499

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/016498 Ceased WO1996019205A1 (fr) 1994-12-21 1995-12-08 Systeme de liberation transdermique avec opercule adhesif et rondelle pelable

Country Status (9)

Country Link
US (1) US5662925A (fr)
EP (1) EP0799029A1 (fr)
JP (1) JPH10511353A (fr)
CN (1) CN1170360A (fr)
AU (1) AU695170B2 (fr)
CA (1) CA2208132A1 (fr)
TW (1) TW438607B (fr)
WO (1) WO1996019205A1 (fr)
ZA (1) ZA9510786B (fr)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962011A (en) * 1993-12-06 1999-10-05 Schering-Plough Healthcare Products, Inc. Device for delivery of dermatological ingredients
DE69709366T2 (de) 1996-07-02 2002-08-08 Minnesota Mining And Manufacturing Company, St. Paul Medizinische klebende zusammensetzung und verpackung
EP0909167B1 (fr) * 1996-07-03 2002-10-30 Alza Corporation Dispositifs d'administration de medicaments et procede de fabrication
US6007837A (en) * 1996-07-03 1999-12-28 Alza Corporation Drug delivery devices and process of manufacture
US5738647A (en) * 1996-09-27 1998-04-14 Becton Dickinson And Company User activated iontophoretic device and method for activating same
US5797867A (en) * 1996-09-27 1998-08-25 Becton Dickinson And Company Iontophoretic drug delivery system, including method for activating same for attachment to patient
US6174545B1 (en) 1997-07-01 2001-01-16 Alza Corporation Drug delivery devices and process of manufacture
US6086912A (en) * 1998-02-11 2000-07-11 Gilman; Marvin S. Topical drug delivery system
US6120792A (en) * 1998-04-29 2000-09-19 Juni; Jack E. Medicated skin patch and method for its use
US6761896B1 (en) * 1998-10-29 2004-07-13 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Skin cosmetic care system and method
US6475514B1 (en) 1998-12-03 2002-11-05 Andrew Blitzer Athletic patch
US6284941B1 (en) 1999-03-09 2001-09-04 Craig M. Cox Bandage having a scar treatment pad for scar management and scar repair
WO2000054755A1 (fr) * 1999-03-17 2000-09-21 Barbara Sheila Goldberg Distributeur adhesif
US20030102246A1 (en) * 1999-03-20 2003-06-05 Lts Lohmann Therapie-Systeme Ag Method for improving the stability of stored and/or used light-sensitive therapeutic systems or components thereof
MXPA02000053A (es) 1999-07-05 2003-07-21 Idea Ag Un metodo para mejorar el tratamiento a traves de barreras adaptables semipermeables.
DE19943317C1 (de) * 1999-09-10 2001-03-15 Lohmann Therapie Syst Lts Kunststofffolien, insbesondere für die Verwendung in einem dermalen oder transdermalen therapeutischen System und Verfahren zu ihrer Herstellung
US6344021B1 (en) * 2000-03-03 2002-02-05 Robert W. Juster Magnetic therapy patch
RU2328276C2 (ru) * 2000-06-01 2008-07-10 Ватсон Фармасьютикалз, Инк. Трансдермальная доставка лазофоксифена
JP4627582B2 (ja) * 2000-06-23 2011-02-09 ニプロパッチ株式会社 経皮吸収又は経粘膜吸収用の投与デバイス
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US20040092494A9 (en) * 2000-08-30 2004-05-13 Dudley Robert E. Method of increasing testosterone and related steroid concentrations in women
US20020119187A1 (en) * 2000-09-29 2002-08-29 Cantor Adam S. Composition for the transdermal delivery of fentanyl
RU2276998C2 (ru) 2001-05-01 2006-05-27 Институт Нефтехимического Синтеза Имени А.В. Топчиева Российской Академии Наук Гидрогелевые композиции
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
CA2447302C (fr) 2001-05-01 2008-07-29 A.V. Topchiev Institute Of Petrochemical Synthesis Composition bioadhesive biphase absorbant l'eau
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
US6506403B1 (en) * 2001-08-21 2003-01-14 Qi Yu Treatment patch
US6676961B1 (en) 2002-03-06 2004-01-13 Automated Carrier Technologies, Inc. Transdermal patch assembly
US7473432B2 (en) 2002-10-11 2009-01-06 Idea Ag NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery
CA2453013C (fr) 2002-12-13 2011-02-15 Gary W. Cleary Dispositifs d'administration d'ingredients par voie percutanee, transdermique ou transmuqueuse ou par les muqueuses
US20040214215A1 (en) * 2003-03-07 2004-10-28 Yu Ruey J. Bioavailability and improved delivery of alkaline pharmaceutical drugs
US20040220264A1 (en) * 2003-03-17 2004-11-04 Yu Ruey J Bioavailability and improved delivery of acidic pharmaceutical drugs
WO2005007020A2 (fr) 2003-07-03 2005-01-27 Corium International, Inc. Pansement, dispositif d'administration d'ingredient et dispositif de fixation intraveineux et procede associe
US8524272B2 (en) 2003-08-15 2013-09-03 Mylan Technologies, Inc. Transdermal patch incorporating active agent migration barrier layer
CN1929819B (zh) 2004-01-30 2012-02-29 考里安国际公司 递送活性剂的快速溶解膜
US20050196418A1 (en) * 2004-03-04 2005-09-08 Yu Ruey J. Bioavailability and improved delivery of alkaline pharmaceutical drugs
ES2526700T3 (es) 2004-08-05 2015-01-14 Corium International, Inc. Composición de adhesivo
RU2389798C2 (ru) 2004-09-14 2010-05-20 Дзе Риджентс Оф Дзе Юниверсити Оф Колорадо, Э Боди Корпорейт Способ лечения буциндололом, основанный на определении генотипа
US7771342B2 (en) * 2004-09-29 2010-08-10 Patrick J. Rademacher Apparatus and method for reducing vision problems as a result of floaters
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
PT2450041T (pt) 2005-10-12 2018-11-16 Unimed Pharmaceuticals Llc Gel de testosterona melhorado e método para a sua utilização
EP1965776A1 (fr) * 2005-12-08 2008-09-10 Fertin Pharma Timbre transdermique d'alcaloide du tabac a faible resistance a la flexion
US8043829B2 (en) * 2006-10-25 2011-10-25 Amgen Inc. DNA encoding chimeric toxin peptide fusion proteins and vectors and mammalian cells for recombinant expression
DE102007006244B4 (de) * 2007-02-08 2012-03-15 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System zur Verabreichung wasserlöslicher Wirkstoffe
CA2687141C (fr) * 2007-05-22 2014-04-01 Amgen Inc. Compositions et procedes pour produire des proteines de fusion bioactives
US20100178323A1 (en) * 2007-07-10 2010-07-15 Agis Kydonieus Dermal Delivery Device
WO2009009651A1 (fr) * 2007-07-10 2009-01-15 Agile Therapeutics, Inc. Dispositif d'administration thermique avec soudure ultrasonore
CN101801321B (zh) * 2007-07-10 2014-07-02 敏捷治疗公司 原位密封的经皮输送装置
US20100028413A1 (en) * 2008-08-04 2010-02-04 Aida Picone Skin treatment strip
EP2201941A1 (fr) * 2008-12-29 2010-06-30 UCB Pharma GmbH Technologie de fabrication de pavé
EP2387394B1 (fr) 2009-01-14 2018-05-02 Corium International, Inc. Administration transdermique de tamsulosine
US8920392B2 (en) 2009-05-05 2014-12-30 Watson Laboratories, Inc. Method for treating overactive bladders and a device for storage and administration of topical oxybutynin compositions
US9512481B2 (en) 2009-09-11 2016-12-06 The Regents Of The University Of Colorado, A Body Corporate Polymorphisms in the PDE3A gene
JP5624147B2 (ja) * 2009-09-30 2014-11-12 メンリッケ・ヘルス・ケア・アーベー フィルム被覆材のキャリア層にグリップタブを取り付ける方法
ES2587191T3 (es) 2009-12-23 2016-10-21 Arca Biopharma, Inc. Métodos y composiciones para enfermedades y afecciones cardiovasculares
WO2012071175A1 (fr) 2010-11-23 2012-05-31 Nupathe, Inc. Système de distribution de médicaments iontophorétique co-emballé autonome activé par l'utilisateur
US9340590B2 (en) 2011-03-16 2016-05-17 Amgen Inc. Potent and selective inhibitors of NaV1.3 and NaV1.7
CA2849910A1 (fr) 2011-09-30 2013-04-04 Perio Sciences, Llc Compositions antioxydantes pour le traitement de l'inflammation ou de dommages oxydatifs
EP2970408B1 (fr) 2013-03-12 2018-01-10 Amgen Inc. Inhibiteurs sélectifs et puissants de nav1.7
WO2015089310A1 (fr) * 2013-12-11 2015-06-18 Atkinson Oscar Revêtement cutané occlusif
US11607026B2 (en) * 2014-05-30 2023-03-21 Johnson & Johnson Consumer Inc. Device for delivery of skin care composition
CN107548308A (zh) * 2014-12-30 2018-01-05 艾利丹尼森公司 用于挤压和缩小疤痕的多层胶带
EP3067050A1 (fr) * 2015-03-13 2016-09-14 Acino AG Système thérapeutique transdermique avec bande de recouvrement comprenant deux couches adhésives
JP6484502B2 (ja) * 2015-06-09 2019-03-13 新光電気工業株式会社 絆創膏型モジュール
KR101636069B1 (ko) * 2015-12-08 2016-07-11 주식회사 라파스 마이크로구조체 제조방법
CA3010183A1 (fr) 2015-12-30 2017-07-06 Corium International, Inc. Systemes et procedes d'administration transdermique a long terme
AU2017281789B2 (en) 2016-06-23 2023-04-13 Corium, LLC. Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent
RU2764764C2 (ru) 2016-07-27 2022-01-21 Кориум Интернэшнл, Инк. Трансдермальные системы доставки мемантина
CA3032044C (fr) 2016-07-27 2024-10-01 Corium Int Inc Systeme d'administration transdermique de donepezil
US11318190B2 (en) 2017-05-05 2022-05-03 United States Government As Represented By The Department Of Veterans Affairs Methods and compositions for treating liver disease
GB2561262B (en) * 2017-07-13 2019-03-20 Dentmed Ltd A targeted drug delivery pad
JP2020529229A (ja) * 2017-07-26 2020-10-08 コリウム, インコーポレイテッド 溶媒充填細孔を有する微多孔膜を有する経皮送達システム
WO2019126531A1 (fr) 2017-12-20 2019-06-27 Corium, Inc. Composition adhésive transdermique comprenant un agent thérapeutique liquide volatil à bas point de fusion
US11185287B2 (en) 2018-06-22 2021-11-30 Vital Connect, Inc. Adhesive overlay

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598122A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US4316893A (en) * 1975-06-19 1982-02-23 Nelson Research & Development Co. Vehicle composition containing 1-substituted azacycloalkan-2-ones
US4405616A (en) * 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
US3989816A (en) * 1975-06-19 1976-11-02 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloheptan-2-ones
US4060084A (en) * 1976-09-07 1977-11-29 Alza Corporation Method and therapeutic system for providing chemotherapy transdermally
EP0040861B1 (fr) * 1979-01-11 1985-04-17 Key Pharmaceuticals, Inc. Matrice polymère à diffusion et méthode pour sa préparation
US4379454A (en) * 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
US4650484A (en) * 1983-02-03 1987-03-17 Alza Corporation Method for treating ischemic conditions
ES8608895A1 (es) * 1984-08-17 1986-07-16 Allpack Ind Lohnverpackung Parche adhesivo farmaceutico y procedimiento para su fabri- cacion
US4710191A (en) * 1985-12-16 1987-12-01 Jonergin, Inc. Therapeutic device for the administration of medicaments
US4863970A (en) * 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
US4849224A (en) * 1987-11-12 1989-07-18 Theratech Inc. Device for administering an active agent to the skin or mucosa
US4983395A (en) * 1987-11-12 1991-01-08 Theratech Inc. Device for administering an active agent to the skin or mucosa
US5202125A (en) * 1990-12-10 1993-04-13 Theratech, Inc. Method and systems for administering nitroglycerin transdermally at enhanced transdermal fluxes
WO1993023019A1 (fr) * 1992-05-11 1993-11-25 Sri International Dispositifs d'apport medicamenteux transcutane, compositions qui y sont associees et procedes d'utilisation

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