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WO1994020539B1 - Procedes et compositions pour la production de proteines osteogenes recombinantes - Google Patents

Procedes et compositions pour la production de proteines osteogenes recombinantes

Info

Publication number
WO1994020539B1
WO1994020539B1 PCT/US1994/002335 US9402335W WO9420539B1 WO 1994020539 B1 WO1994020539 B1 WO 1994020539B1 US 9402335 W US9402335 W US 9402335W WO 9420539 B1 WO9420539 B1 WO 9420539B1
Authority
WO
WIPO (PCT)
Prior art keywords
binding partner
protein
osteogenic protein
species
subunit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1994/002335
Other languages
English (en)
Other versions
WO1994020539A1 (fr
Filing date
Publication date
Application filed filed Critical
Priority to JP6520181A priority Critical patent/JPH08510446A/ja
Priority to AU63588/94A priority patent/AU682176B2/en
Priority to DE69434914T priority patent/DE69434914T2/de
Priority to EP94910830A priority patent/EP0687272B1/fr
Publication of WO1994020539A1 publication Critical patent/WO1994020539A1/fr
Publication of WO1994020539B1 publication Critical patent/WO1994020539B1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Abstract

Nouvelles compositions de protéines ostéogènes constituant des formes solubles de ces protéines, et procédés et compositions permettant de distinguer entre les formes solubles et matures de ces protéines.
PCT/US1994/002335 1993-03-04 1994-03-04 Procedes et compositions pour la production de proteines osteogenes recombinantes Ceased WO1994020539A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP6520181A JPH08510446A (ja) 1993-03-04 1994-03-04 組換え骨形成タンパク質を生成するための方法および組成物
AU63588/94A AU682176B2 (en) 1993-03-04 1994-03-04 Method and compositions for recombinant osteogenic protein production
DE69434914T DE69434914T2 (de) 1993-03-04 1994-03-04 Verfahren und zusammensetzungen zur herstellung von rekombinantem osteogenischem protein
EP94910830A EP0687272B1 (fr) 1993-03-04 1994-03-04 Procedes et compositions pour la production de proteines osteogenes recombinantes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2707093A 1993-03-04 1993-03-04
US027,070 1993-03-04

Publications (2)

Publication Number Publication Date
WO1994020539A1 WO1994020539A1 (fr) 1994-09-15
WO1994020539B1 true WO1994020539B1 (fr) 1994-10-27

Family

ID=21835518

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/002335 Ceased WO1994020539A1 (fr) 1993-03-04 1994-03-04 Procedes et compositions pour la production de proteines osteogenes recombinantes

Country Status (6)

Country Link
EP (1) EP0687272B1 (fr)
JP (2) JPH08510446A (fr)
AU (1) AU682176B2 (fr)
CA (1) CA2157387C (fr)
DE (1) DE69434914T2 (fr)
WO (1) WO1994020539A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2141555C (fr) * 1992-07-31 2007-03-27 William K. Jones Complexe proteinique morphogene soluble et composition a base de celui-ci
US6498142B1 (en) 1996-05-06 2002-12-24 Curis, Inc. Morphogen treatment for chronic renal failure
TW562807B (en) * 1997-04-01 2003-11-21 Chugai Pharmaceutical Co Ltd Novel secretory membrane protein
AU743510B2 (en) 1997-05-05 2002-01-24 Stryker Corporation Therapies for acute renal failure
CA2652549A1 (fr) * 2006-05-17 2007-12-13 Stryker Corporation Procede pour traiter des defauts cartilagineux a l'aide d'uncomplexe de proteine morphogenique soluble
US9809636B2 (en) 2012-04-06 2017-11-07 Acceleron Pharma Inc. Methods for increasing red blood cell levels comprising administering BMP9

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE243254T1 (de) * 1988-04-08 2003-07-15 Stryker Corp Biosynthetische knochenbildende proteine, und sie enthaltende knochenbildende vorrichtungen
US5284756A (en) * 1988-10-11 1994-02-08 Lynn Grinna Heterodimeric osteogenic factor
ES2161693T3 (es) * 1991-03-11 2001-12-16 Curis Inc Morfogenesis inducida por proteinas.
IT1259042B (it) * 1992-01-27 1996-03-11 Mini Ricerca Scient Tecnolog Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante
CA2141555C (fr) * 1992-07-31 2007-03-27 William K. Jones Complexe proteinique morphogene soluble et composition a base de celui-ci

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WO1994020539B1 (fr) Procedes et compositions pour la production de proteines osteogenes recombinantes
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