|
US4704362A
(en)
|
1977-11-08 |
1987-11-03 |
Genentech, Inc. |
Recombinant cloning vehicle microbial polypeptide expression
|
|
GB8308235D0
(en)
*
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
*
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5208036A
(en)
*
|
1985-01-07 |
1993-05-04 |
Syntex (U.S.A.) Inc. |
N-(ω, (ω-1)-dialkyloxy)- and N-(ω, (ω-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
|
|
US4666829A
(en)
*
|
1985-05-15 |
1987-05-19 |
University Of California |
Polypeptide marker for Alzheimer's disease and its use for diagnosis
|
|
US5618920A
(en)
*
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
US4713366A
(en)
|
1985-12-04 |
1987-12-15 |
The Ohio State University Research Foundation |
Antigenic modification of polypeptides
|
|
US5096706A
(en)
*
|
1986-03-25 |
1992-03-17 |
National Research Development Corporation |
Antigen-based treatment for adiposity
|
|
US5225539A
(en)
*
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US6548640B1
(en)
*
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
|
JPS62267297A
(ja)
|
1986-05-15 |
1987-11-19 |
Tokyo Met Gov Seishin Igaku Sogo Kenkyusho |
老人斑反応性モノクロ−ナル抗体、それを産生する細胞株及び該モノクロ−ナル抗体の製造方法
|
|
US5278049A
(en)
*
|
1986-06-03 |
1994-01-11 |
Incyte Pharmaceuticals, Inc. |
Recombinant molecule encoding human protease nexin
|
|
US5231170A
(en)
*
|
1986-08-27 |
1993-07-27 |
Paul Averback |
Antibodies to dense microspheres
|
|
US5220013A
(en)
*
|
1986-11-17 |
1993-06-15 |
Scios Nova Inc. |
DNA sequence useful for the detection of Alzheimer's disease
|
|
US5187153A
(en)
|
1986-11-17 |
1993-02-16 |
Scios Nova Inc. |
Methods of treatment using Alzheimer's amyloid polypeptide derivatives
|
|
US4879213A
(en)
|
1986-12-05 |
1989-11-07 |
Scripps Clinic And Research Foundation |
Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
|
|
DE3702789A1
(de)
|
1987-01-30 |
1988-08-18 |
Bayer Ag |
Vorlaeuferprotein des apc-polypeptids, dafuer codierende dna und diagnostische verwendung der dna und des proteins
|
|
US4912206A
(en)
*
|
1987-02-26 |
1990-03-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
CDNA clone encoding brain amyloid of alzheimer's disease
|
|
WO1988007089A1
(en)
*
|
1987-03-18 |
1988-09-22 |
Medical Research Council |
Altered antibodies
|
|
JPS63245689A
(ja)
|
1987-03-31 |
1988-10-12 |
Suntory Ltd |
ヒトアミロイド関連蛋白モノクロ−ナル抗体
|
|
US4883666A
(en)
|
1987-04-29 |
1989-11-28 |
Massachusetts Institute Of Technology |
Controlled drug delivery system for treatment of neural disorders
|
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
|
US5583112A
(en)
|
1987-05-29 |
1996-12-10 |
Cambridge Biotech Corporation |
Saponin-antigen conjugates and the use thereof
|
|
US5057540A
(en)
|
1987-05-29 |
1991-10-15 |
Cambridge Biotech Corporation |
Saponin adjuvant
|
|
US5245015A
(en)
|
1991-04-26 |
1993-09-14 |
Tanox Biosystems, Inc. |
Monoclonal antibodies which neutralize HIV-1 through reaction with a conformational epitope in vitro
|
|
US5571499A
(en)
|
1987-06-24 |
1996-11-05 |
Autoimmune, Inc. |
Treatment of autoimmune diseases by aerosol administration of autoantigens
|
|
US5571500A
(en)
|
1987-06-24 |
1996-11-05 |
Autoimmune, Inc. |
Treatment of autoimmune diseases through administration by inhalation of autoantigens
|
|
US5641474A
(en)
*
|
1987-06-24 |
1997-06-24 |
Autoimmune, Inc. |
Prevention of autoimmune diseases by aerosol administration of autoantigens
|
|
US5645820A
(en)
*
|
1987-06-24 |
1997-07-08 |
Autoimmune, Inc. |
Treatment of autoimmune diseases by aerosol administration of autoantigens
|
|
US5849298A
(en)
|
1987-06-24 |
1998-12-15 |
Autoimmune Inc. |
Treatment of multiple sclerosis by oral administration of bovine myelin
|
|
US5869054A
(en)
*
|
1987-06-24 |
1999-02-09 |
Autoimmune Inc. |
Treatment of multiple sclerosis by oral administration of autoantigens
|
|
EP0666080B1
(en)
|
1987-06-24 |
2004-01-21 |
Brigham & Women's Hospital |
Treatment of autoimmune diseases by oral administration of autoantigens
|
|
US5004697A
(en)
|
1987-08-17 |
1991-04-02 |
Univ. Of Ca |
Cationized antibodies for delivery through the blood-brain barrier
|
|
US5677425A
(en)
|
1987-09-04 |
1997-10-14 |
Celltech Therapeutics Limited |
Recombinant antibody
|
|
CA1339014C
(en)
|
1987-10-08 |
1997-03-25 |
Ronald E. Majocha |
Antibodies to a4 amyloid peptide
|
|
US5231000A
(en)
*
|
1987-10-08 |
1993-07-27 |
The Mclean Hospital |
Antibodies to A4 amyloid peptide
|
|
AU2728588A
(en)
|
1987-10-23 |
1989-05-23 |
Genetics Institute Inc. |
Composition and method for treating cancers characterized by over-expression of the c-fms proto-oncogene
|
|
US5089603A
(en)
|
1989-06-21 |
1992-02-18 |
Tanox Biosystems, Inc. |
Antigenic epitopes present on membrane-bound but not secreted iga
|
|
AU3056289A
(en)
|
1988-01-13 |
1989-08-11 |
Mclean Hospital Corporation, The |
Genetic constructs containing the alzheimer brain amyloid gene
|
|
US4912094B1
(en)
|
1988-06-29 |
1994-02-15 |
Ribi Immunochem Research Inc. |
Modified lipopolysaccharides and process of preparation
|
|
US5576184A
(en)
|
1988-09-06 |
1996-11-19 |
Xoma Corporation |
Production of chimeric mouse-human antibodies with specificity to human tumor antigens
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5227159A
(en)
*
|
1989-01-31 |
1993-07-13 |
Miller Richard A |
Anti-idiotype antibodies reactive with shared idiotopes expressed by B cell lymphomas and autoantibodies
|
|
US5262332A
(en)
|
1989-04-05 |
1993-11-16 |
Brigham And Women's Hospital |
Diagnostic method for Alzheimer's disease: examination of non-neural tissue
|
|
WO1990012870A1
(en)
|
1989-04-14 |
1990-11-01 |
Research Foundation For Mental Hygiene, Inc. |
Monoclonal antibody to amyloid peptide
|
|
AU5439790A
(en)
|
1989-04-14 |
1990-11-16 |
Research Foundation For Mental Hygiene, Inc. |
Cerebrovascular amyloid protein-specific monoclonal antibody sv17-6e10
|
|
HUT61487A
(en)
|
1989-12-20 |
1993-01-28 |
Brigham & Womens Hospital |
Process for producing aerosol pharmaceutical composition comprising autoantigens
|
|
GB8928874D0
(en)
*
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
US5859205A
(en)
*
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
EP0594607B1
(en)
|
1990-03-02 |
1997-08-27 |
Autoimmune, Inc. |
Enhancement of the down-regulation of autoimmune diseases by oral or enteral administration of autoantigens
|
|
EP0451700A1
(en)
|
1990-04-10 |
1991-10-16 |
Miles Inc. |
Recombinant APP minigenes for expression in transgenic mice as models for Alzheimers's disease
|
|
WO1991016628A1
(en)
|
1990-04-24 |
1991-10-31 |
The Regents Of The University Of California |
Purification, detection and methods of use of protease nexin-2
|
|
GB9009548D0
(en)
|
1990-04-27 |
1990-06-20 |
Celltech Ltd |
Chimeric antibody and method
|
|
CA2081482C
(en)
|
1990-04-27 |
2000-11-21 |
Ellis L. Kline |
Method and composition for treatment of central nervous system disease states associated with abnormal amyloid beta protein molecular organization
|
|
US5753624A
(en)
|
1990-04-27 |
1998-05-19 |
Milkhaus Laboratory, Inc. |
Materials and methods for treatment of plaquing disease
|
|
ATE260974T1
(de)
*
|
1990-06-15 |
2004-03-15 |
Scios Inc |
Transgenes, nicht-menschliches säugetier das die amyloidbildende pathologie der alzheimerschen krankheit zeigt
|
|
US5780587A
(en)
*
|
1990-08-24 |
1998-07-14 |
President And Fellows Of Harvard College |
Compounds and methods for inhibiting β-protein filament formation and neurotoxicity
|
|
US6506728B2
(en)
|
1990-09-25 |
2003-01-14 |
Genentech, Inc. |
Methods using a novel neurotrophic factor, NT-4
|
|
CA2092823A1
(en)
|
1990-09-28 |
1992-03-29 |
Barry D. Greenberg |
Transgenic animals with alzheimer's amyloid precursor gene
|
|
JP2635444B2
(ja)
|
1990-10-15 |
1997-07-30 |
オートイミューン インク |
自己抗体の経口投与による自己免疫性疾患の治療
|
|
US5877015A
(en)
|
1991-01-21 |
1999-03-02 |
Imperial College Of Science, Technology Of Medicine |
APP770 mutant in alzheimer's disease
|
|
US5192753A
(en)
*
|
1991-04-23 |
1993-03-09 |
Mcgeer Patrick L |
Anti-rheumatoid arthritic drugs in the treatment of dementia
|
|
WO1994004679A1
(en)
*
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
JP4124480B2
(ja)
*
|
1991-06-14 |
2008-07-23 |
ジェネンテック・インコーポレーテッド |
免疫グロブリン変異体
|
|
US5672805A
(en)
|
1991-07-18 |
1997-09-30 |
The Regents Of The University Of California |
Transgenic mice expressing the neurotoxic C-terminus of β-amyloid precursor protein
|
|
JP2966592B2
(ja)
|
1991-07-20 |
1999-10-25 |
萩原 義秀 |
安定化されたヒトモノクローナル抗体製剤
|
|
US5434050A
(en)
|
1991-08-13 |
1995-07-18 |
Regents Of The University Of Minnesota |
Labelled β-amyloid peptide and methods of screening for Alzheimer's disease
|
|
US5837268A
(en)
|
1991-10-16 |
1998-11-17 |
University Of Saskatchewan |
GnRH-leukotoxin chimeras
|
|
AU671093B2
(en)
|
1992-01-07 |
1996-08-15 |
Elan Pharmaceuticals, Inc. |
Transgenic animal models for alzheimer's disease
|
|
US5679348A
(en)
|
1992-02-03 |
1997-10-21 |
Cedars-Sinai Medical Center |
Immunotherapy for recurrent HSV infections
|
|
ATE245446T1
(de)
|
1992-02-11 |
2003-08-15 |
Jackson H M Found Military Med |
Dualer träger für immunogene konstrukte
|
|
CA2117492C
(en)
|
1992-02-28 |
2009-04-07 |
Howard L. Weiner |
Bystander suppression of autoimmune diseases
|
|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
|
EP0561087B1
(en)
|
1992-03-20 |
1999-08-04 |
N.V. Innogenetics S.A. |
Mutated form of the beta-amyloid precursor protein gene
|
|
US5441870A
(en)
*
|
1992-04-15 |
1995-08-15 |
Athena Neurosciences, Inc. |
Methods for monitoring cellular processing of β-amyloid precursor protein
|
|
US5604102A
(en)
*
|
1992-04-15 |
1997-02-18 |
Athena Neurosciences, Inc. |
Methods of screening for β-amyloid peptide production inhibitors
|
|
US5851787A
(en)
*
|
1992-04-20 |
1998-12-22 |
The General Hospital Corporation |
Nucleic acid encoding amyloid precursor-like protein and uses thereof
|
|
AU4116793A
(en)
|
1992-04-24 |
1993-11-29 |
Board Of Regents, The University Of Texas System |
Recombinant production of immunoglobulin-like domains in prokaryotic cells
|
|
GB9209118D0
(en)
|
1992-04-28 |
1992-06-10 |
Sb 120 Amsterdam Bv |
Vaccine compositions
|
|
DE69327534T2
(de)
*
|
1992-06-18 |
2000-06-08 |
The President And Fellows Of Harvard College, Cambridge |
Impfstoffe gegen diphtherietoxin
|
|
NZ253137A
(en)
|
1992-06-25 |
1996-08-27 |
Smithkline Beecham Biolog |
Vaccine comprising antigen and/or antigenic composition, qs21 (quillaja saponaria molina extract) and 3 de-o-acylated monophosphoryl lipid a.
|
|
US5837672A
(en)
|
1992-07-10 |
1998-11-17 |
Athena Neurosciences, Inc. |
Methods and compositions for the detection of soluble β-amyloid peptide
|
|
US6610493B1
(en)
|
1993-06-17 |
2003-08-26 |
Brigham And Women's Hospital |
Screening compounds for the ability to alter the production of amyloid-β peptide
|
|
US5766846A
(en)
*
|
1992-07-10 |
1998-06-16 |
Athena Neurosciences |
Methods of screening for compounds which inhibit soluble β-amyloid peptide production
|
|
WO1994001772A1
(en)
|
1992-07-13 |
1994-01-20 |
The Children's Medical Center Corporation |
SCREEN FOR ALZHEIMER'S DISEASE THERAPEUTICS BASED ON β-AMYLOID PRODUCTION
|
|
AU4719393A
(en)
|
1992-07-31 |
1994-03-03 |
Medeva Holdings B.V. |
Expression of recombinant fusion proteins in attenuated bacteria
|
|
NZ255256A
(en)
|
1992-08-27 |
1997-02-24 |
Deakin Res Ltd |
Synthetic peptide antigen analogues with retro, inverso or retro-inverso modification, their use and antibodies against them
|
|
US5958883A
(en)
|
1992-09-23 |
1999-09-28 |
Board Of Regents Of The University Of Washington Office Of Technology |
Animal models of human amyloidoses
|
|
AU5358494A
(en)
|
1992-10-13 |
1994-05-09 |
Duke University |
Method of inhibiting binding of amyloid precursor protein to beta-amyloid protein
|
|
US5605811A
(en)
*
|
1992-10-26 |
1997-02-25 |
Athena Neurosciences, Inc. |
Methods and compositions for monitoring cellular processing of beta-amyloid precursor protein
|
|
JP3553592B2
(ja)
|
1992-10-26 |
2004-08-11 |
ビー． シェンク，デイル |
可溶性β−アミロイド・ペプチドの検出のための方法及び組成物
|
|
US6210671B1
(en)
*
|
1992-12-01 |
2001-04-03 |
Protein Design Labs, Inc. |
Humanized antibodies reactive with L-selectin
|
|
US5955317A
(en)
|
1993-01-25 |
1999-09-21 |
Takeda Chemical Industries, Ltd. |
Antibodies to β-amyloids or their derivatives and use thereof
|
|
EP1308461A3
(en)
*
|
1993-01-25 |
2004-02-11 |
Takeda Chemical Industries, Ltd. |
Antibodies to beta-amyloids or their derivatives and use thereof
|
|
US5358708A
(en)
|
1993-01-29 |
1994-10-25 |
Schering Corporation |
Stabilization of protein formulations
|
|
CA2115811A1
(en)
*
|
1993-02-17 |
1994-08-18 |
Claus Krebber |
A method for in vivo selection of ligand-binding proteins
|
|
CA2115900A1
(en)
|
1993-02-22 |
1994-08-23 |
Gerald W. Becker |
Pharmaceutical screens and antibodies
|
|
CA2158455C
(en)
*
|
1993-03-17 |
2003-05-27 |
Nicholas P. Restifo |
Immunogenic chimeras comprising nucleic acid sequences encoding endoplasmic reticulum signal sequence peptides and at least one other peptide and their uses in vaccines and disease treatments
|
|
US5776468A
(en)
*
|
1993-03-23 |
1998-07-07 |
Smithkline Beecham Biologicals (S.A.) |
Vaccine compositions containing 3-0 deacylated monophosphoryl lipid A
|
|
IT1270939B
(it)
|
1993-05-11 |
1997-05-26 |
Angeletti P Ist Richerche Bio |
Procedimento per la preparazione di immunogeni e reagenti diagnostici,e immunogeni e reagenti diagnostici cosi' ottenibili.
|
|
WO1994028412A1
(en)
|
1993-05-28 |
1994-12-08 |
The Miriam Hospital |
Composition and method for in vivo imaging of amyloid deposits
|
|
US5464823A
(en)
|
1993-07-20 |
1995-11-07 |
The Regents Of The University Of California |
Mammalian antibiotic peptides
|
|
ATE215124T1
(de)
|
1993-07-30 |
2002-04-15 |
Medeva Holdings Bv |
Rekombinante tetc-fusionsprotein enthaltene impfstoffzusammensetzungen
|
|
CA2146667A1
(en)
|
1993-08-18 |
1995-02-23 |
Adolf Hoess |
Lipopolysaccharide-binding and neutralizing peptides
|
|
AU707083B2
(en)
|
1993-08-26 |
1999-07-01 |
Bavarian Nordic Inc. |
Inducing antibody response against self-proteins with the aid of foreign T-cell epitopes
|
|
DK96493D0
(da)
|
1993-08-26 |
1993-08-26 |
Mouritsen Og Elsner Aps |
Fremgangsmaade til at inducere antistofresponser mod selvproteiner og autovaccine fremstillet ved fremgangsmaaden
|
|
WO1995005853A1
(en)
|
1993-08-26 |
1995-03-02 |
The Regents Of The University Of California |
Method, compositions and devices for administration of naked polynucleotides which encode biologically active peptides
|
|
WO1995006407A1
(en)
|
1993-08-30 |
1995-03-09 |
The Regents Of The University Of California |
Novel component of amyloid in alzheimer's disease and methods for use of same
|
|
EP0730609B1
(en)
|
1993-09-07 |
2005-01-05 |
Smithkline Beecham Corporation |
Recombinant il4 antibodies useful in treatment of il4 mediated disorders
|
|
US5652334A
(en)
*
|
1993-09-08 |
1997-07-29 |
City Of Hope |
Method for design of substances that enhance memory and improve the quality of life
|
|
US5385887A
(en)
*
|
1993-09-10 |
1995-01-31 |
Genetics Institute, Inc. |
Formulations for delivery of osteogenic proteins
|
|
PT735893E
(pt)
*
|
1993-09-14 |
2009-03-06 |
Pharmexa Inc |
Péptidos que se ligam aos alelos pan dr para aumentar a resposta imunitária
|
|
US5470951A
(en)
|
1993-09-29 |
1995-11-28 |
City Of Hope |
Peptides for antagonizing the effects of amyloid βprotein
|
|
US5858981A
(en)
|
1993-09-30 |
1999-01-12 |
University Of Pennsylvania |
Method of inhibiting phagocytosis
|
|
CA2174501A1
(en)
|
1993-10-20 |
1995-04-27 |
Warren J. Strittmatter |
Method of binding material to the .beta.-amyloid peptide
|
|
JP3504963B2
(ja)
|
1993-10-22 |
2004-03-08 |
智靖 羅 |
抗ヒト高親和性ＩｇＥ受容体モノクローナル抗体に係るアミノ酸配列をコードするＤＮＡ断片
|
|
ATE223702T1
(de)
|
1993-10-22 |
2002-09-15 |
Genentech Inc |
Verfahren und zusammensetzungen zur mikrokapselung von adjuvantien
|
|
US5744368A
(en)
|
1993-11-04 |
1998-04-28 |
Research Foundation Of State University Of New York |
Methods for the detection of soluble amyloid β-protein (βAP) or soluble transthyretin (TTR)
|
|
JPH07132033A
(ja)
|
1993-11-12 |
1995-05-23 |
Hoechst Japan Ltd |
アルツハイマー病モデルトランスジェニック動物
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
US5434170A
(en)
*
|
1993-12-23 |
1995-07-18 |
Andrulis Pharmaceuticals Corp. |
Method for treating neurocognitive disorders
|
|
GB9326253D0
(en)
|
1993-12-23 |
1994-02-23 |
Smithkline Beecham Biolog |
Vaccines
|
|
US5877399A
(en)
*
|
1994-01-27 |
1999-03-02 |
Johns Hopkins University |
Transgenic mice expressing APP-Swedish mutation develop progressive neurologic disease
|
|
CA2182311A1
(en)
*
|
1994-01-27 |
1995-08-03 |
Karen Hsiao |
Transgenic non-human mammals with progressive neurologic disease
|
|
WO1995020979A1
(en)
|
1994-02-03 |
1995-08-10 |
The Picower Institute For Medical Research |
Compositions and methods for advanced glycosylation endproduct-mediated modulation of amyloidosis
|
|
AUPM411994A0
(en)
|
1994-02-25 |
1994-03-24 |
Deakin Research Limited |
Epitopes
|
|
US5795954A
(en)
|
1994-03-04 |
1998-08-18 |
Genentech, Inc. |
Factor VIIa inhibitors from Kunitz domain proteins
|
|
US6270757B1
(en)
|
1994-04-21 |
2001-08-07 |
Genetics Institute, Inc. |
Formulations for IL-11
|
|
US6372716B1
(en)
*
|
1994-04-26 |
2002-04-16 |
Genetics Institute, Inc. |
Formulations for factor IX
|
|
AU686818B2
(en)
|
1994-05-25 |
1998-02-12 |
John Mcmichael |
Materials and methods for treatment of plaquing diseases
|
|
US5622701A
(en)
*
|
1994-06-14 |
1997-04-22 |
Protein Design Labs, Inc. |
Cross-reacting monoclonal antibodies specific for E- and P-selectin
|
|
US6417178B1
(en)
*
|
1994-07-19 |
2002-07-09 |
University Of Pittsburgh |
Amyloid binding nitrogen-linked compounds for the antemortem diagnosis of alzheimer's disease, in vivo imaging and prevention of amyloid deposits
|
|
US6114133A
(en)
|
1994-11-14 |
2000-09-05 |
Elan Pharmaceuticals, Inc. |
Methods for aiding in the diagnosis of Alzheimer's disease by measuring amyloid-β peptide (x-≧41)
|
|
US5589154A
(en)
|
1994-11-22 |
1996-12-31 |
Rutgers, The State University Of New Jersey |
Methods for the prevention or treatment of vascular hemorrhaging and Alzheimer's disease
|
|
US5688651A
(en)
|
1994-12-16 |
1997-11-18 |
Ramot University Authority For Applied Research And Development Ltd. |
Prevention of protein aggregation
|
|
DE69620877T2
(de)
*
|
1995-02-06 |
2002-12-12 |
Genetics Institute, Inc. |
Arzneimittelformulierungen für il-12
|
|
US5786180A
(en)
|
1995-02-14 |
1998-07-28 |
Bayer Corporation |
Monoclonal antibody 369.2B specific for β A4 peptide
|
|
US5624937A
(en)
|
1995-03-02 |
1997-04-29 |
Eli Lilly And Company |
Chemical compounds as inhibitors of amyloid beta protein production
|
|
US6303567B1
(en)
|
1995-03-14 |
2001-10-16 |
Praecis Pharmaceuticals, Inc . |
Modulators of β-amyloid peptide aggregation comprising D-amino acids
|
|
US5817626A
(en)
|
1995-03-14 |
1998-10-06 |
Praecis Pharmaceuticals Incorporated |
Modulators of beta-amyloid peptide aggregation
|
|
US5854215A
(en)
|
1995-03-14 |
1998-12-29 |
Praecis Pharmaceuticals Incorporated |
Modulators of β-amyloid peptide aggregation
|
|
JPH11514333A
(ja)
|
1995-03-14 |
1999-12-07 |
プレーシス ファーマスーティカルズ インコーポレイテッド |
アミロイドの凝集の調節剤
|
|
US5869046A
(en)
*
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
EP0827544B1
(en)
|
1995-05-23 |
2004-08-18 |
MorphoSys AG |
Multimeric proteins
|
|
WO1996039176A1
(en)
|
1995-06-05 |
1996-12-12 |
Brigham & Women's Hospital |
USE OF ORAL TOLERANCE TO SUPPRESS BOTH Th1 AND Th2 IMMUNE RESPONSES AND TO SUPPRESS ANTIBODY PRODUCTION
|
|
ATE214603T1
(de)
|
1995-06-30 |
2002-04-15 |
American Cyanamid Co |
Stabile makrolide und makrolide imptstoff- zusammensetzungen
|
|
JP4073955B2
(ja)
|
1995-07-07 |
2008-04-09 |
ダーウィン モレキュラー コーポレイション |
アルツハイマー病に関連する第１染色体の遺伝子および遺伝子産物
|
|
US6267958B1
(en)
*
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
|
US6685940B2
(en)
|
1995-07-27 |
2004-02-03 |
Genentech, Inc. |
Protein formulation
|
|
DK1143006T3
(da)
|
1995-08-18 |
2008-07-14 |
Morphosys Ip Gmbh |
Vektorer/DNA-sekvenser fra humane kombinatoriske antistofbiblioteker
|
|
US5824322A
(en)
|
1995-08-21 |
1998-10-20 |
Cytrx Corporation |
Compositions and methods for growth promotion
|
|
JP3495738B2
(ja)
*
|
1995-09-14 |
2004-02-09 |
ザ レジェンツ オブ ザ ユニバーシティー オブ カリフォルニア |
天然ＰｒＰｓｃ特異的抗体
|
|
US5731284A
(en)
|
1995-09-28 |
1998-03-24 |
Amgen Inc. |
Method for treating Alzheimer's disease using glial line-derived neurotrophic factor (GDNF) protein product
|
|
US5985242A
(en)
|
1995-10-27 |
1999-11-16 |
Praecis Pharmaceuticals, Inc. |
Modulators of β-amyloid peptide aggregation comprising D-amino acids
|
|
US5750361A
(en)
*
|
1995-11-02 |
1998-05-12 |
The Regents Of The University Of California |
Formation and use of prion protein (PRP) complexes
|
|
CA2235226A1
(en)
|
1995-11-10 |
1997-05-15 |
Elan Corporation, Plc |
Peptides which enhance transport across tissues and methods of identifying and using the same
|
|
WO1997021728A1
(en)
|
1995-12-12 |
1997-06-19 |
Karolinska Innovations Ab |
PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b)
|
|
JPH09178743A
(ja)
|
1995-12-27 |
1997-07-11 |
Oriental Yeast Co Ltd |
可溶性ａｐｐの定量法
|
|
US6015662A
(en)
*
|
1996-01-23 |
2000-01-18 |
Abbott Laboratories |
Reagents for use as calibrators and controls
|
|
US5770700A
(en)
*
|
1996-01-25 |
1998-06-23 |
Genetics Institute, Inc. |
Liquid factor IX formulations
|
|
JP2000505306A
(ja)
|
1996-02-26 |
2000-05-09 |
モルフォシス・アクチェンゲゼルシャフト |
２つまたはそれ以上の相互作用性（ポリ）ペプチドをコードする核酸配列の新規同定方法
|
|
US6150091A
(en)
|
1996-03-06 |
2000-11-21 |
Baylor College Of Medicine |
Direct molecular diagnosis of Friedreich ataxia
|
|
US6372225B1
(en)
|
1996-03-23 |
2002-04-16 |
The Research Foundation Of Microbial Diseases Of Osaka University |
Tetanus toxin functional fragment antigen and tetanus vaccine
|
|
US6284533B1
(en)
|
1996-05-01 |
2001-09-04 |
Avant Immunotherapeutics, Inc. |
Plasmid-based vaccine for treating atherosclerosis
|
|
DE69726003T2
(de)
|
1996-07-16 |
2004-08-26 |
Andreas Plückthun |
Immunglobulin-superfamilie domainen und fragmente mit erhöhter löslichkeit
|
|
CA2183901A1
(en)
|
1996-08-22 |
1998-02-23 |
Johanna E. Bergmann |
Targets for therapy and diagnosis of alzheimer's disease and down syndrome in humans
|
|
EP0929574B1
(en)
|
1996-08-27 |
2005-06-29 |
Praecis Pharmaceuticals Incorporated |
MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS
|
|
US6057367A
(en)
*
|
1996-08-30 |
2000-05-02 |
Duke University |
Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses
|
|
US6797495B2
(en)
|
1996-11-05 |
2004-09-28 |
The Regents Of The University Of California |
Somatic cells with ablated PrP gene and methods of use
|
|
US6022859A
(en)
*
|
1996-11-15 |
2000-02-08 |
Wisconsin Alumni Research Foundation |
Inhibitors of β-amyloid toxicity
|
|
AU5508798A
(en)
|
1996-11-19 |
1998-06-10 |
Trustees Of The University Of Pennsylvania, The |
Diagnostic and therapeutic reagents for alzheimer's disease
|
|
US6962984B2
(en)
|
1996-12-05 |
2005-11-08 |
Nihon University |
IgA nephropathy-related DNA
|
|
US6218506B1
(en)
*
|
1997-02-05 |
2001-04-17 |
Northwestern University |
Amyloid β protein (globular assembly and uses thereof)
|
|
US20030068316A1
(en)
|
1997-02-05 |
2003-04-10 |
Klein William L. |
Anti-ADDL antibodies and uses thereof
|
|
US6277375B1
(en)
|
1997-03-03 |
2001-08-21 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
|
US5798102A
(en)
|
1997-03-04 |
1998-08-25 |
Milkhaus Laboratory, Inc. |
Treatment of cardiomyopathy
|
|
US20020086847A1
(en)
*
|
1997-04-09 |
2002-07-04 |
Mindset Biopharmaceuticals (Usa) |
Recombinant antibodies specific for beta-amyloid ends, DNA encoding and methods of use thereof
|
|
EP2006303A1
(en)
|
1997-04-09 |
2008-12-24 |
Intellect Neurosciences, Inc. |
Recombinant antibodies specific for Beta-Amyloid ends, DNA encoding and methods of use thereof
|
|
US8173127B2
(en)
*
|
1997-04-09 |
2012-05-08 |
Intellect Neurosciences, Inc. |
Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof
|
|
US6787319B2
(en)
*
|
1997-04-16 |
2004-09-07 |
American Home Products Corp. |
β-amyloid peptide-binding proteins and polynucleotides encoding the same
|
|
DE69838294T2
(de)
|
1997-05-20 |
2009-08-13 |
Ottawa Health Research Institute, Ottawa |
Verfahren zur Herstellung von Nukleinsäurekonstrukten
|
|
WO1998056418A1
(en)
|
1997-06-13 |
1998-12-17 |
Genentech, Inc. |
Stabilized antibody formulation
|
|
WO1999000150A2
(en)
|
1997-06-27 |
1999-01-07 |
Regents Of The University Of California |
Drug targeting of a peptide radiopharmaceutical through the primate blood-brain barrier in vivo with a monoclonal antibody to the human insulin receptor
|
|
IT1293511B1
(it)
|
1997-07-30 |
1999-03-01 |
Gentili Ist Spa |
Anticorpi monoclonali catalitici ad attivita' proteasica per la lisi selettiva della componente proteica di placche e aggregati correlati
|
|
JP2002501721A
(ja)
|
1997-08-01 |
2002-01-22 |
モルフォシス・アクチェンゲゼルシャフト |
多量体（ポリ）ペプチドコンプレックスのメンバーをコードする核酸配列を同定するための新規方法およびファージ
|
|
DE69842048D1
(de)
|
1997-08-01 |
2011-01-27 |
Max Planck Gesellschaft |
Zusammensetzung und verfahren zum nachweis von krankheiten in zusammenhang mit der bildung von amyloid-ähnlichen fibrillen oder protein-aggregaten
|
|
ES2500490T3
(es)
|
1997-08-29 |
2014-09-30 |
Antigenics Inc. |
Composiciones que comprenden el adyuvante QS-21 y polisorbato o ciclodextrina como excipiente
|
|
US6175057B1
(en)
*
|
1997-10-08 |
2001-01-16 |
The Regents Of The University Of California |
Transgenic mouse model of alzheimer's disease and cerebral amyloid angiopathy
|
|
CA2251263A1
(en)
|
1997-11-14 |
1999-05-14 |
Hajime Karasuyama |
Transgenic animal allergy models and methods for their use
|
|
US6761888B1
(en)
|
2000-05-26 |
2004-07-13 |
Neuralab Limited |
Passive immunization treatment of Alzheimer's disease
|
|
US6750324B1
(en)
*
|
1997-12-02 |
2004-06-15 |
Neuralab Limited |
Humanized and chimeric N-terminal amyloid beta-antibodies
|
|
US6710226B1
(en)
*
|
1997-12-02 |
2004-03-23 |
Neuralab Limited |
Transgenic mouse assay to determine the effect of Aβ antibodies and Aβ Fragments on alzheimer's disease characteristics
|
|
US6923964B1
(en)
|
1997-12-02 |
2005-08-02 |
Neuralab Limited |
Active immunization of AScr for prion disorders
|
|
US7790856B2
(en)
|
1998-04-07 |
2010-09-07 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6905686B1
(en)
*
|
1997-12-02 |
2005-06-14 |
Neuralab Limited |
Active immunization for treatment of alzheimer's disease
|
|
TWI239847B
(en)
|
1997-12-02 |
2005-09-21 |
Elan Pharm Inc |
N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
|
|
US7179892B2
(en)
|
2000-12-06 |
2007-02-20 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
US20080050367A1
(en)
|
1998-04-07 |
2008-02-28 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6787523B1
(en)
|
1997-12-02 |
2004-09-07 |
Neuralab Limited |
Prevention and treatment of amyloidogenic disease
|
|
US6913745B1
(en)
*
|
1997-12-02 |
2005-07-05 |
Neuralab Limited |
Passive immunization of Alzheimer's disease
|
|
US7964192B1
(en)
|
1997-12-02 |
2011-06-21 |
Janssen Alzheimer Immunotherapy |
Prevention and treatment of amyloidgenic disease
|
|
NZ504711A
(en)
|
1997-12-03 |
2002-02-01 |
Fujisawa Pharmaceutical Co |
Soft-pellet drug and process for the preparation thereof
|
|
DE1033998T1
(de)
|
1997-12-03 |
2001-05-23 |
Brigham And Women's Hospital, Boston |
Methode zur unterdrückung von beta-amyloid-verwandten veränderungen in alzheimer
|
|
FR2777015B3
(fr)
|
1998-02-23 |
2000-09-15 |
Financ De Biotechnologie |
Procede et moyens pour l'obtention de modeles cellulaires et animaux de maladies neurodegeneratives
|
|
US6528624B1
(en)
*
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
|
US6194551B1
(en)
*
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
US20050059802A1
(en)
*
|
1998-04-07 |
2005-03-17 |
Neuralab Ltd |
Prevention and treatment of amyloidogenic disease
|
|
US20050059591A1
(en)
*
|
1998-04-07 |
2005-03-17 |
Neuralab Limited |
Prevention and treatment of amyloidogenic disease
|
|
ES2230848T3
(es)
|
1998-04-28 |
2005-05-01 |
Smithkline Beecham Corporation |
Anticuerpos monoclonales con inmunogenicidad reducida.
|
|
NO314086B1
(no)
|
1998-05-08 |
2003-01-27 |
Gemvax As |
Peptider og farmasöytiske sammensetninger inneholdende disse, nukleinsyresekvenser som koder for slike peptider, plasmider og virusvektoreromfattende slike DNA-sekvenser samt anvendelse av disse for fremstilling avfarmasöytiske preparater til
|
|
CA2328612A1
(en)
|
1998-05-19 |
1999-11-25 |
Yeda Research And Development Co., Ltd. |
Activated t cells, nervous system-specific antigens and their uses
|
|
US20030147882A1
(en)
|
1998-05-21 |
2003-08-07 |
Alan Solomon |
Methods for amyloid removal using anti-amyloid antibodies
|
|
EP1078005B1
(en)
|
1998-05-21 |
2010-04-21 |
University Of Tennessee Research Foundation |
Methods for amyloid removal using anti-amyloid antibodies
|
|
US6727349B1
(en)
*
|
1998-07-23 |
2004-04-27 |
Millennium Pharmaceuticals, Inc. |
Recombinant anti-CCR2 antibodies and methods of use therefor
|
|
ES2222728T3
(es)
|
1998-10-05 |
2005-02-01 |
Pharmexa A/S |
Procedimiento de vacunacion terapeutica.
|
|
EP1150688A4
(en)
|
1998-10-19 |
2004-06-16 |
Yeda Res & Dev |
TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS BY NEGATIVE REGULATION OF THE AUTO-IMMUNE RESPONSE TO AUTOANTIGENS
|
|
GB2348203B
(en)
|
1998-11-04 |
2002-06-19 |
Imp College Innovations Ltd |
Solube beta-forms of prion proteins, methods of preparation and use
|
|
ES2216509T3
(es)
|
1999-01-19 |
2004-10-16 |
PHARMACIA & UPJOHN COMPANY |
Procedimiento de envasado para sustancias medicinales sensibles a la oxidacion.
|
|
AU775525B2
(en)
|
1999-01-22 |
2004-08-05 |
Auckland Technology Enabling Corporation Limited |
Vaccine-mediated treatment of neurological disorders
|
|
AU4529800A
(en)
|
1999-05-05 |
2000-11-21 |
Neurochem, Inc. |
Stereoselective antifibrillogenic peptides and peptidomimetics thereof
|
|
US6787637B1
(en)
|
1999-05-28 |
2004-09-07 |
Neuralab Limited |
N-Terminal amyloid-β antibodies
|
|
PE20010212A1
(es)
|
1999-06-01 |
2001-02-22 |
Neuralab Ltd |
Composiciones del peptido a-beta y procesos para producir las mismas
|
|
UA81216C2
(en)
|
1999-06-01 |
2007-12-25 |
|
Prevention and treatment of amyloid disease
|
|
DK1409654T3
(da)
|
1999-06-16 |
2008-12-08 |
Boston Biomedical Res Inst |
Immunologisk styring af beta-amyloid-niveauer in vivo
|
|
PL360914A1
(en)
|
1999-07-15 |
2004-09-20 |
Genetics Institute Inc. |
Formulations for il-11
|
|
DE60043165D1
(de)
|
1999-08-04 |
2009-11-26 |
Univ Southern California |
Globularer Aufbau vom Amyloid-beta- protein und deren Verwendungen
|
|
US6919075B1
(en)
|
1999-09-03 |
2005-07-19 |
Ramot At Tel Aviv University Ltd. |
Bacteriophage displaying aβ epitopes and method of use
|
|
US6294171B2
(en)
|
1999-09-14 |
2001-09-25 |
Milkhaus Laboratory, Inc. |
Methods for treating disease states comprising administration of low levels of antibodies
|
|
US20020094335A1
(en)
*
|
1999-11-29 |
2002-07-18 |
Robert Chalifour |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
WO2001039796A2
(en)
|
1999-11-29 |
2001-06-07 |
Neurochem Inc. |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
IL149976A0
(en)
|
1999-12-08 |
2002-12-01 |
Mindset Biopharmaceuticals Usa |
Chimeric peptides as immunogens, antibodies thereto, and methods for immunization using chimeric peptides or antibodies
|
|
US6399314B1
(en)
*
|
1999-12-29 |
2002-06-04 |
American Cyanamid Company |
Methods of detection of amyloidogenic proteins
|
|
CA2400838C
(en)
|
2000-02-21 |
2013-04-23 |
Pharmexa A/S |
Novel method for down-regulation of amyloid
|
|
US20030086938A1
(en)
|
2000-02-21 |
2003-05-08 |
Jensen Martin Roland |
Novel methods for down-regulation of amyloid
|
|
DE1257584T1
(de)
|
2000-02-24 |
2003-05-28 |
Lilly Co Eli |
Humanisierte antikörper, die amyloid beta peptid demarkieren
|
|
CA2404237C
(en)
|
2000-04-05 |
2010-01-26 |
University Of Tennessee Research Corporation |
Methods of investigating, diagnosing, and treating amyloidosis
|
|
PT1284998E
(pt)
|
2000-05-22 |
2005-06-30 |
Univ New York |
Eptideos imunogenicos sinteticos mas nao-amiloidogenicos homologos a beta-amiloides, destinados a induzir uma reaccao imunitaria contra os beta-amiloides e os depositos amiloides
|
|
EP2082749A3
(en)
|
2000-07-07 |
2010-06-30 |
Bioarctic Neuroscience AB |
Prevention and treatment of Alzheimer's disease
|
|
US20020009445A1
(en)
*
|
2000-07-12 |
2002-01-24 |
Yansheng Du |
Human beta-amyloid antibody and use thereof for treatment of alzheimer's disease
|
|
EP1172378A1
(en)
|
2000-07-12 |
2002-01-16 |
Richard Dr. Dodel |
Human beta-amyloid antibody and use thereof for treatment of alzheimer's disease
|
|
US20030092145A1
(en)
|
2000-08-24 |
2003-05-15 |
Vic Jira |
Viral vaccine composition, process, and methods of use
|
|
DE60139788D1
(de)
|
2000-09-06 |
2009-10-15 |
Aventis Pharma Sa |
Verfahren und zusammensetzungen für amyloidosis-verbundene krankheiten
|
|
IT1319277B1
(it)
|
2000-10-24 |
2003-09-26 |
Chiesi Farma Spa |
Proteine di fusione utili per il trattamento di immunizzazione dellamalattia di alzheimer.
|
|
IL139308A0
(en)
|
2000-10-26 |
2001-11-25 |
Marikovsky Moshe |
Peptides from amyloid precursor protein which inhibit tumor growth and metastasis
|
|
US20020133001A1
(en)
|
2000-11-27 |
2002-09-19 |
Praecis Pharmaceuticals Inc. |
Therapeutic agents and methods of use thereof for treating an amyloidogenic disease
|
|
US7700751B2
(en)
|
2000-12-06 |
2010-04-20 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize β-amyloid peptide
|
|
PE20020574A1
(es)
|
2000-12-06 |
2002-07-02 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido amiloideo beta
|
|
US6900036B2
(en)
|
2000-12-27 |
2005-05-31 |
University Of Texas Health Science Center Houston |
Prion isomers, methods of making, methods of using, and compositions and products comprising prion isomers
|
|
US20020160394A1
(en)
|
2001-01-24 |
2002-10-31 |
Bayer Corporation |
Regulation of transthyretin to treat obesity
|
|
DE60121729T2
(de)
|
2001-04-19 |
2007-11-29 |
Dr. Hermann Schätzl |
Prion Proteindimere für Impfungen
|
|
AU2002257162A1
(en)
|
2001-04-30 |
2002-11-11 |
Eli Lilly And Company |
Humanized antibodies
|
|
AU2002258808A1
(en)
|
2001-04-30 |
2002-11-11 |
Eli Lilly And Company |
Humanized antibodies
|
|
US6906169B2
(en)
*
|
2001-05-25 |
2005-06-14 |
United Biomedical, Inc. |
Immunogenic peptide composition comprising measles virus Fprotein Thelper cell epitope (MUFThl-16) and N-terminus of β-amyloid peptide
|
|
GB0113179D0
(en)
|
2001-05-31 |
2001-07-25 |
Novartis Ag |
Organic compounds
|
|
AU2002345843A1
(en)
|
2001-06-22 |
2003-01-08 |
Panacea Pharmaceuticals, Inc. |
Compositions and methods for preventing protein aggregation in neurodegenerative diseases
|
|
CA2454587C
(en)
|
2001-07-25 |
2012-11-13 |
Protein Design Labs, Inc. |
Stable lyophilized pharmaceutical formulation of igg antibodies
|
|
US20030135035A1
(en)
|
2001-08-09 |
2003-07-17 |
Mark Shannon |
Human ZZAP1 protein
|
|
CA2452104A1
(en)
*
|
2001-08-17 |
2003-02-27 |
Eli Lilly And Company |
Use of antibodies having high affinity for soluble ass to treat conditions and diseases related to ass
|
|
EP1519740A4
(en)
|
2001-08-17 |
2005-11-09 |
Lilly Co Eli |
FASTER IMPROVEMENT OF COGNITION IN DISEASES ASSOCIATED WITH A-BETA
|
|
US20040192898A1
(en)
|
2001-08-17 |
2004-09-30 |
Jia Audrey Yunhua |
Anti-abeta antibodies
|
|
US20030082191A1
(en)
|
2001-08-29 |
2003-05-01 |
Poduslo Joseph F. |
Treatment for central nervous system disorders
|
|
US7781413B2
(en)
|
2001-10-31 |
2010-08-24 |
Board Of Regents, The University Of Texas System |
SEMA3B inhibits tumor growth and induces apoptosis in cancer cells
|
|
NZ532896A
(en)
|
2001-11-08 |
2007-08-31 |
Pdl Biopharma Inc |
Stable liquid pharmaceutical formulation of IGG antibodies including daclizumab and fontolizumab
|
|
AU2002357007A1
(en)
|
2001-11-21 |
2003-06-10 |
New York University |
SYNTHETIC IMMUNOGENIC BUT NON-DEPOSIT-FORMING POLYPEPTIDES AND PEPTIDES HOMOLOGOUS TO AMYLOID Beta, PRION PROTEIN, AMYLIN, Alpha-SYNUCLEIN, OR POLYGLUTAMINE REPEATS FOR INDUCTION OF AN IMMUNE RESPONSE THERETO
|
|
US20050227941A1
(en)
|
2001-12-17 |
2005-10-13 |
Karen Duff |
Sequestration of ass in the periphery in the absence of immunomodulating agent as a therapeutic approach for the treatment or prevention of beta-amyloid related diseases
|
|
AR038568A1
(es)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
|
CN1646161A
(zh)
|
2002-02-21 |
2005-07-27 |
杜克大学 |
自身免疫疾病的药剂和治疗方法
|
|
MY139983A
(en)
*
|
2002-03-12 |
2009-11-30 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
|
WO2004013172A2
(en)
|
2002-07-24 |
2004-02-12 |
Innogenetics N.V. |
Fragments of beta-amyloid as targets for vaccination against alzheimer disease
|
|
EP1545582A4
(en)
|
2002-10-01 |
2008-09-17 |
Univ Northwestern |
DIFFUSIBLE DERIVATIVES DERIVED FROM AMYLOID BETA (ADDL), ADDL SUBSTITUTE, ADDL BINDING MOLECULES, AND USES THEREOF
|
|
FR2846667B1
(fr)
*
|
2002-11-06 |
2004-12-31 |
Pasteur Institut |
Fragments variables d'anticorps de camelides a chaine unique diriges contre le peptide beta-amyloide 1-42 et leurs applications pour le diagnostic et le traitement des maladies neuroagregatives
|
|
AU2003293543A1
(en)
|
2002-12-13 |
2004-07-09 |
Abgenix, Inc. |
System and method for stabilizing antibodies with histidine
|
|
PL378571A1
(pl)
|
2003-02-01 |
2006-05-02 |
Neuralab Limited |
Czynna immunizacja dla wytworzenia przeciwciał przeciw rozpuszczalnemu A-ß
|
|
ATE468886T1
(de)
*
|
2003-02-10 |
2010-06-15 |
Applied Molecular Evolution |
Abeta-bindende moleküle
|
|
PL1610820T5
(pl)
|
2003-04-04 |
2014-01-31 |
Genentech Inc |
Preparaty zawierające wysokoskoncentrowane przeciwciała i białka
|
|
EP1480041A1
(en)
|
2003-05-22 |
2004-11-24 |
Innogenetics N.V. |
Method for the prediction, diagnosis and differential diagnosis of Alzheimer's disease
|
|
PE20050627A1
(es)
*
|
2003-05-30 |
2005-08-10 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido beta amiloideo
|
|
WO2005014041A2
(en)
|
2003-07-24 |
2005-02-17 |
Novartis Ag |
Use of an amyloid beta dna vaccine for the treatment and/or prevention of amyloid diseases
|
|
WO2005026211A2
(en)
|
2003-09-05 |
2005-03-24 |
Eli Lilly And Company |
Anti-ghrelin antibodies
|
|
PH12011502391A1
(en)
|
2003-12-17 |
2014-04-28 |
Janssen Alzheimer Immunotherap |
Aã immunogenic peptide carrier conjugates and methods of producing same
|
|
EA012984B1
(ru)
|
2003-12-17 |
2010-02-26 |
Вайет |
Конъюгаты иммуногенных пептидных носителей и способы их получения
|
|
AU2005294131A1
(en)
|
2004-10-05 |
2006-04-20 |
Wyeth |
Methods and compositions for improving recombinant protein production
|
|
US20060160161A1
(en)
|
2004-10-26 |
2006-07-20 |
Elan Pharmaceuticals, Inc. |
Methods for assessing antibodies to neurodegenerative disease-associated antigens
|
|
TW200635608A
(en)
*
|
2004-12-15 |
2006-10-16 |
Neuralab Ltd |
Aβ antibodies for use in improving cognition
|
|
WO2006066118A2
(en)
|
2004-12-15 |
2006-06-22 |
Neuralab Limited |
Contextual fear test for predicting efficacy of alzheimer immunotherapeutic treatment
|
|
WO2006066233A1
(en)
|
2004-12-15 |
2006-06-22 |
Neuralab Limited |
An immunoprecipitation-based assay for predicting in vivo efficacy of beta-amyloid antibodies
|
|
PE20061329A1
(es)
|
2004-12-15 |
2006-12-08 |
Neuralab Ltd |
Anticuerpos ab humanizados para mejorar la cognicion
|
|
US7625560B2
(en)
|
2004-12-15 |
2009-12-01 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize beta amyloid peptide
|
|
CN101111264A
(zh)
|
2005-01-28 |
2008-01-23 |
惠氏公司 |
稳定化的液体多肽制剂
|
|
GT200600031A
(es)
|
2005-01-28 |
2006-08-29 |
|
Formulacion anticuerpo anti a beta
|
|
NZ565044A
(en)
|
2005-06-17 |
2010-05-28 |
Elan Pharma Int Ltd |
Methods of purifying anti A beta antibodies with calcium chloride
|