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UY27846A1 - Compuestos quimicos - Google Patents

Compuestos quimicos

Info

Publication number
UY27846A1
UY27846A1 UY27846A UY27846A UY27846A1 UY 27846 A1 UY27846 A1 UY 27846A1 UY 27846 A UY27846 A UY 27846A UY 27846 A UY27846 A UY 27846A UY 27846 A1 UY27846 A1 UY 27846A1
Authority
UY
Uruguay
Prior art keywords
chemical compounds
solvates
salts
compounds
ibat
Prior art date
Application number
UY27846A
Other languages
English (en)
Inventor
Starke Ingemar
Dahlstrnm Mikael Ulf Johan
Lemurell Malin Anita
Alenfalk Suzanne
Skjrret Tore
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY27846A1 publication Critical patent/UY27846A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

La presente invención se relaciona con compuestos de fórmula (I) : ( en donde los grupos variables son como se definen en la presente) sales, solvatos, solvatos de dichas sales y profármacos farmacéuticamente aceptables de los mismos y su uso como inhibidores del transporte de ácido biliar ileal (IBAT) para el tratamiento de hiperlipidemia. También se describen procesos para su fabricación y composiciones farmacéuticas que los contienen.
UY27846A 2002-06-14 2003-06-12 Compuestos quimicos UY27846A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0213669.5A GB0213669D0 (en) 2002-06-14 2002-06-14 Chemical compounds

Publications (1)

Publication Number Publication Date
UY27846A1 true UY27846A1 (es) 2003-12-31

Family

ID=9938564

Family Applications (1)

Application Number Title Priority Date Filing Date
UY27846A UY27846A1 (es) 2002-06-14 2003-06-12 Compuestos quimicos

Country Status (25)

Country Link
US (1) US7192947B2 (es)
EP (1) EP1515984B1 (es)
JP (1) JP4423191B2 (es)
KR (1) KR20050010514A (es)
CN (1) CN1659182A (es)
AR (1) AR039672A1 (es)
AT (1) ATE424407T1 (es)
AU (1) AU2003240079B2 (es)
BR (1) BR0311628A (es)
CA (1) CA2489463A1 (es)
DE (1) DE60326451D1 (es)
ES (1) ES2321826T3 (es)
GB (1) GB0213669D0 (es)
IS (1) IS7597A (es)
MX (1) MXPA04012603A (es)
MY (1) MY134270A (es)
NO (1) NO20045099L (es)
NZ (1) NZ537122A (es)
PL (1) PL372626A1 (es)
RU (1) RU2315772C2 (es)
SA (1) SA03240217B1 (es)
TW (1) TWI282790B (es)
UY (1) UY27846A1 (es)
WO (1) WO2003106482A1 (es)
ZA (1) ZA200409860B (es)

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Also Published As

Publication number Publication date
WO2003106482A1 (en) 2003-12-24
ATE424407T1 (de) 2009-03-15
ZA200409860B (en) 2005-10-19
TWI282790B (en) 2007-06-21
US20050222120A1 (en) 2005-10-06
DE60326451D1 (de) 2009-04-16
NO20045099L (no) 2005-01-06
PL372626A1 (en) 2005-07-25
MXPA04012603A (es) 2005-03-23
JP4423191B2 (ja) 2010-03-03
AU2003240079A1 (en) 2003-12-31
KR20050010514A (ko) 2005-01-27
IS7597A (is) 2004-12-15
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RU2315772C2 (ru) 2008-01-27
AU2003240079B2 (en) 2007-11-15
AR039672A1 (es) 2005-03-09
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GB0213669D0 (en) 2002-07-24
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