[go: up one dir, main page]

UA97095C2 - Противораковая вакцина, которая содержит опухолевоассоциированный пептид, который связывается с молекулами лейкоцитарного антигена человека (hla) класса i или ii, и ее применение в производстве лекарственного средства - Google Patents

Противораковая вакцина, которая содержит опухолевоассоциированный пептид, который связывается с молекулами лейкоцитарного антигена человека (hla) класса i или ii, и ее применение в производстве лекарственного средства

Info

Publication number
UA97095C2
UA97095C2 UAA200803781A UAA200803781A UA97095C2 UA 97095 C2 UA97095 C2 UA 97095C2 UA A200803781 A UAA200803781 A UA A200803781A UA A200803781 A UAA200803781 A UA A200803781A UA 97095 C2 UA97095 C2 UA 97095C2
Authority
UA
Ukraine
Prior art keywords
molecules
tumour
hla
class
tumor
Prior art date
Application number
UAA200803781A
Other languages
English (en)
Ukrainian (uk)
Inventor
Харпреет Зингх
Нильс Эммерих
Штеффен Вальтер
Тони Вайншенк
Original Assignee
Имматикс Биотекнолоджис Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Имматикс Биотекнолоджис Гмбх filed Critical Имматикс Биотекнолоджис Гмбх
Publication of UA97095C2 publication Critical patent/UA97095C2/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Изобретение относится к противораковой вакцине, которая содержит опухолеассоциированный пептид, который включает последовательность согласно SEQ ID NO: 1, которая имеет общую длину от 16 до 30 аминокислот, и применение этой вакцины в производстве лекарственного средства для уничтожения раковых клеток у пациента.
UAA200803781A 2005-09-05 2006-09-05 Противораковая вакцина, которая содержит опухолевоассоциированный пептид, который связывается с молекулами лейкоцитарного антигена человека (hla) класса i или ii, и ее применение в производстве лекарственного средства UA97095C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05019255A EP1760089B1 (en) 2005-09-05 2005-09-05 Tumor-associated peptides binding to human leukocyte antigen (HLA) class I or II molecules and related anti-cancer vaccine
PCT/EP2006/008641 WO2007028573A1 (en) 2005-09-05 2006-09-05 Tumor-associated peptides binding to human leukocyte antigen (hla) class i or ii molecules and related anti-cancer vaccine

Publications (1)

Publication Number Publication Date
UA97095C2 true UA97095C2 (ru) 2012-01-10

Family

ID=35149455

Family Applications (2)

Application Number Title Priority Date Filing Date
UAA201111468A UA105210C2 (ru) 2005-09-05 2006-09-05 Противораковая вакцина и ее применение
UAA200803781A UA97095C2 (ru) 2005-09-05 2006-09-05 Противораковая вакцина, которая содержит опухолевоассоциированный пептид, который связывается с молекулами лейкоцитарного антигена человека (hla) класса i или ii, и ее применение в производстве лекарственного средства

Family Applications Before (1)

Application Number Title Priority Date Filing Date
UAA201111468A UA105210C2 (ru) 2005-09-05 2006-09-05 Противораковая вакцина и ее применение

Country Status (23)

Country Link
US (1) US20090274714A1 (ru)
EP (2) EP1760089B1 (ru)
JP (1) JP5132561B2 (ru)
KR (1) KR101150663B1 (ru)
CN (1) CN101287755B (ru)
AT (2) ATE440107T1 (ru)
AU (1) AU2006289289B2 (ru)
BR (1) BRPI0615466A2 (ru)
CA (1) CA2621414C (ru)
CY (2) CY1110536T1 (ru)
DE (2) DE602005016112D1 (ru)
DK (2) DK1760089T3 (ru)
EA (1) EA013466B1 (ru)
ES (2) ES2330013T3 (ru)
HR (1) HRP20110240T1 (ru)
NO (1) NO20081690L (ru)
NZ (1) NZ565956A (ru)
PL (2) PL1760089T3 (ru)
PT (2) PT1760089E (ru)
RS (1) RS51893B (ru)
SI (2) SI1760089T1 (ru)
UA (2) UA105210C2 (ru)
WO (1) WO2007028573A1 (ru)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1806359B1 (en) 2005-09-05 2010-03-17 Immatics Biotechnologies GmbH Tumor-associated peptides binding promiscuously to human leukocyte antigen (HLA) class II molecules
US20090004213A1 (en) 2007-03-26 2009-01-01 Immatics Biotechnologies Gmbh Combination therapy using active immunotherapy
ES2321680B1 (es) * 2007-04-26 2010-03-05 Fundacion Para La Investigacion Biosanitaria De Andalucia Oriental - Alejandro Otero (Fibao) Restauracion de las moleculas hla de clase i mediante terapia genica empleando vectores adenovirales portando el gen de la beta 2-microglobulina.
EA018456B1 (ru) * 2007-07-27 2013-08-30 Имматикс Байотекнолоджиз Гмбх Новые иммуногенные эпитопы для иммунотерапии
UA103882C2 (ru) 2007-07-27 2013-12-10 Імматікс Біотекнолоджіс Гмбх Композиция опухолево-ассоциированных пептидов и соответствующая противораковая вакцина
MX2010001086A (es) 2007-07-27 2010-04-09 Immatics Biotechnologies Gmbh Nueva inmunoterapia contra tumores neuronales y cerebrales.
CY1112212T1 (el) * 2008-04-24 2015-12-09 Immatics Biotechnologies Gmbh Νεα σκευασματα πεπτιδιων που σχετιζονται με ογκους τα οποια συνδεονται σε μορια του αντιγονου ανθρωπινων λευκοκυτταρων (hla) ταξης i ή ii για εμβολια
PT2113253E (pt) * 2008-04-30 2010-06-15 Immatics Biotechnologies Gmbh Formulações novas de peptídeos associados a tumores que se ligam a moléculas de classe i ou ii do antígeno leucocitário humano (hla) para vacinas
SI2119726T2 (en) 2008-05-14 2018-03-30 Immatics Biotechnologies Gmbh New and powerful Class II MHC peptides derived from survivin and neurocane
AU2016204708B2 (en) * 2008-10-01 2018-02-22 Immatics Biotechnologies Gmbh Novel immunotherapy against several tumors including neuronal and brain tumors
PT2172211E (pt) * 2008-10-01 2015-03-09 Immatics Biotechnologies Gmbh Composição de peptídeos associados a tumores e vacina anti -cancro relacionada para o tratamento de glioblastoma (gbm) e outros tipos de câncer
GB201004551D0 (en) * 2010-03-19 2010-05-05 Immatics Biotechnologies Gmbh NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer
GB201004575D0 (en) 2010-03-19 2010-05-05 Immatics Biotechnologies Gmbh Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers
GB201006360D0 (en) * 2010-04-16 2010-06-02 Immatics Biotechnologies Gmbh Method for differentially quantifying naturally processed HLA-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development
GB201009222D0 (en) * 2010-06-02 2010-07-21 Immatics Biotechnologies Gmbh Improved cancer therapy based on tumour associated antigens derived from cyclin D1
ES2677118T3 (es) * 2010-12-02 2018-07-30 Oncotherapy Science, Inc. Péptidos de TOMM34 y vacunas que incluyen los mismos
JP2014521599A (ja) * 2011-07-05 2014-08-28 カディラ ファーマシューティカルズ リミテッド がん抗原
MY170949A (en) * 2011-07-11 2019-09-20 Cancer Res Initiatives Foundation A peptide capable of binding with a human leukocyte antigen (hla) molecule, a cancer vaccine derived from said peptide and use of said cancer vaccine
AU2013280416B2 (en) 2012-06-27 2017-06-15 Rutgers, The State University Of New Jersey Rapid assays for T-cell activation by RNA measurements using flow cytometry
US20140017267A1 (en) * 2012-07-13 2014-01-16 Matthias W Rath Metalloproteinase oligopeptides and their therapeutic use
TWI777196B (zh) * 2013-08-05 2022-09-11 德商伊瑪提克斯生物科技有限公司 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物(五)
KR20160097290A (ko) 2013-12-09 2016-08-17 타르고바스 에이에스에이 펩타이드 혼합물
LT3545965T (lt) 2014-12-23 2021-09-10 Immatics Biotechnologies Gmbh Nauji peptidai ir peptidų deriniai, skirti naudoti imunoterapijai prieš hepatoceliulinę karcinomą (hck) ir kitų rūšių vėžį
GB201501017D0 (en) 2014-12-23 2015-03-04 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers
ES2790725T3 (es) * 2015-03-16 2020-10-29 Max Delbrueck Centrum Fuer Molekulare Medizin Helmholtz Gemeinschaft Procedimiento de detección de nuevos epítopos de células T inmunogénicas y aislamiento de nuevos receptores de células T específicas de antígeno mediante una biblioteca de células de MHC
TWI755157B (zh) 2015-03-17 2022-02-11 德商英麥提克生物技術股份有限公司 用於抗胰臟癌與其他癌症的免疫治療的新穎胜肽及胜肽的組合
GB201504502D0 (en) * 2015-03-17 2015-04-29 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers
GB201505305D0 (en) 2015-03-27 2015-05-13 Immatics Biotechnologies Gmbh Novel Peptides and combination of peptides for use in immunotherapy against various tumors
PL3388075T3 (pl) 2015-03-27 2023-12-11 Immatics Biotechnologies Gmbh Nowe peptydy i kombinacja peptydów do stosowania w immunoterapii względem różnych nowotworów
GB201505585D0 (en) * 2015-03-31 2015-05-13 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carinoma (RCC) and other cancers
GB201507030D0 (en) * 2015-04-24 2015-06-10 Immatics Biotechnologies Gmbh Immunotherapy against lung cancers, in particular NSCLC
AU2016280839B2 (en) * 2015-06-19 2020-07-16 Immatics Biotechnologies Gmbh Peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer and other cancers
GB201510771D0 (en) 2015-06-19 2015-08-05 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer
GB201511191D0 (en) 2015-06-25 2015-08-12 Immatics Biotechnologies Gmbh T-cell epitopes for the immunotherapy of myeloma
HK1254866A1 (zh) 2015-06-25 2019-07-26 Immatics Biotechnologies Gmbh 用於骨髓瘤和其他癌症免疫治疗的新型细胞表位和细胞表位组合物
HRP20202019T1 (hr) 2015-07-01 2021-04-30 Immatics Biotechnologies Gmbh Novi peptidi i kombinacija peptida za uporabu u imunoterapiji protiv raka jajnika i drugih malignih tumora
GB201511546D0 (en) 2015-07-01 2015-08-12 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
GB201511792D0 (en) * 2015-07-06 2015-08-19 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against esopageal cancer and other cancers
CN113880938B (zh) 2015-07-06 2025-09-05 伊玛提克斯生物技术有限公司 用于食管癌和其他癌症免疫治疗的新型肽和肽组合物
GB201512369D0 (en) * 2015-07-15 2015-08-19 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against epithelial ovarian cancer and other cancers
HK1258386A1 (zh) 2015-10-05 2019-11-08 Immatics Biotechnologies Gmbh 用於小细胞肺癌和其他癌症免疫治疗的肽和肽组合物
GB201517538D0 (en) 2015-10-05 2015-11-18 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers
EP3167898A1 (en) 2015-11-11 2017-05-17 IEO - Istituto Europeo di Oncologia Srl Method for obtaining tumor peptides and uses thereof
EP3383427A4 (en) * 2015-12-04 2019-11-27 Mayo Foundation for Medical Education and Research METHOD AND VACCINES FOR INDUCTION OF IMMUNE REACTIONS TO SEVERAL DIFFERENT MHC MOLECULES
IL298653A (en) 2015-12-11 2023-01-01 Immatics Biotechnologies Gmbh New peptides and a combination of peptides for use in immunotherapy against several types of cancer
GB201521894D0 (en) * 2015-12-11 2016-01-27 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against various cancers
EP3419656A4 (en) * 2016-02-22 2019-10-30 Oceanside Biotechnology NEOANTIGEN COMPOSITIONS AND METHODS FOR USE THEREOF IN IMMUNOOTHERAPY
PE20181923A1 (es) * 2016-03-31 2018-12-11 Neon Therapeutics Inc Neoantigenos y metodos de su uso
TWI796299B (zh) * 2016-08-26 2023-03-21 德商英麥提克生物技術股份有限公司 用於頭頸鱗狀細胞癌和其他癌症免疫治療的新型肽和支架
EP4317432A3 (en) 2016-12-08 2024-04-17 Immatics Biotechnologies GmbH T cell receptors with improved pairing
DE102016123893A1 (de) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T-Zellrezeptoren mit verbesserter Bindung
CN106986932A (zh) * 2017-04-06 2017-07-28 海口市人民医院 一种c‑Met表位肽及其应用
WO2019160099A1 (ja) * 2018-02-15 2019-08-22 大塚製薬株式会社 がん抗原ペプチド
CN110804642B (zh) * 2019-09-10 2022-06-21 清华大学 Gpr174免疫学功能及其用途
KR20220100664A (ko) * 2019-11-14 2022-07-15 보가지치 유니버시테시 암 면역요법에서의 asc speck
CN114524870A (zh) * 2020-11-23 2022-05-24 香雪生命科学技术(广东)有限公司 源自于ssx2抗原的短肽
CA3216268A1 (en) * 2021-04-23 2022-10-27 Scott Burkholz Vaccine for sars-cov-2
CN118620040A (zh) * 2022-01-05 2024-09-10 成都朗谷生物科技股份有限公司 一种针对乙型肝炎病毒的抗原肽

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4440859A (en) 1977-05-27 1984-04-03 The Regents Of The University Of California Method for producing recombinant bacterial plasmids containing the coding sequences of higher organisms
US4704362A (en) 1977-11-08 1987-11-03 Genentech, Inc. Recombinant cloning vehicle microbial polypeptide expression
LU88258I2 (ru) 1978-12-22 1994-02-03
US4530901A (en) 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
US4678751A (en) 1981-09-25 1987-07-07 Genentech, Inc. Hybrid human leukocyte interferons
US4766075A (en) 1982-07-14 1988-08-23 Genentech, Inc. Human tissue plasminogen activator
US4582800A (en) 1982-07-12 1986-04-15 Hoffmann-La Roche Inc. Novel vectors and method for controlling interferon expression
US4757006A (en) 1983-10-28 1988-07-12 Genetics Institute, Inc. Human factor VIII:C gene and recombinant methods for production
US4677063A (en) 1985-05-02 1987-06-30 Cetus Corporation Human tumor necrosis factor
US4810648A (en) 1986-01-08 1989-03-07 Rhone Poulenc Agrochimie Haloarylnitrile degrading gene, its use, and cells containing the gene
EP0671926B1 (en) * 1992-08-11 2002-11-13 President And Fellows Of Harvard College Immunomodulatory peptides
AUPM322393A0 (en) 1993-12-24 1994-01-27 Austin Research Institute, The Mucin carbohydrate compounds and their use in immunotherapy
CN1180843C (zh) 1994-07-27 2004-12-22 昆士兰医学研究所 多表位疫苗
ES2203782T3 (es) 1996-01-17 2004-04-16 Imperial College Innovations Limited Inmunoterapia que utiliza linfocitos t citotoxicos (ctl).
US6096313A (en) * 1996-02-09 2000-08-01 Ludwig Institute For Cancer Research Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant
US6316213B1 (en) * 1997-03-19 2001-11-13 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian, breast and lung cancer
IL125608A0 (en) * 1998-07-30 1999-03-12 Yeda Res & Dev Tumor associated antigen peptides and use of same as anti-tumor vaccines
DE19917195B4 (de) 1999-04-16 2006-09-28 Immatics Biotechnologies Gmbh Peptid zur Auslösung einer Immunreaktion gegen Tumorzellen, diese enthaltende pharmzeutische Zusammensetzungen, dessen Verwendungen, dafür codierende Nukleinsäure und diese Nukleinsäure enthaltender Expressionsvektor
KR100358068B1 (ko) * 1999-12-28 2002-10-25 주식회사 하이닉스반도체 플래쉬 메모리 소자의 제조방법
AU2002368151A1 (en) * 2002-08-13 2004-02-25 Warner-Lambert Company Llc Matrix metalloproteinase inhibitors and methods for identification of lead compounds
US20060045881A1 (en) * 2004-08-26 2006-03-02 Board Of Regents, The University Of Texas System Anti-cancer vaccines

Also Published As

Publication number Publication date
CA2621414C (en) 2016-10-04
NO20081690L (no) 2008-04-04
CN101287755A (zh) 2008-10-15
ATE440107T1 (de) 2009-09-15
PL1922334T3 (pl) 2011-06-30
JP5132561B2 (ja) 2013-01-30
CA2621414A1 (en) 2007-03-15
EA013466B1 (ru) 2010-04-30
AU2006289289B2 (en) 2012-04-19
WO2007028573A1 (en) 2007-03-15
DE602006019446D1 (de) 2011-02-17
EP1760089A1 (en) 2007-03-07
PT1922334E (pt) 2011-04-01
SI1922334T1 (sl) 2011-04-29
DK1760089T3 (da) 2009-11-16
UA105210C2 (ru) 2014-04-25
EA200800676A1 (ru) 2008-08-29
US20090274714A1 (en) 2009-11-05
AU2006289289A1 (en) 2007-03-15
RS51893B (sr) 2012-02-29
HRP20110240T1 (en) 2011-05-31
ES2358802T3 (es) 2011-05-13
ES2330013T3 (es) 2009-12-03
PL1760089T3 (pl) 2010-03-31
WO2007028573A9 (en) 2008-05-02
KR101150663B1 (ko) 2012-05-25
EP1922334A1 (en) 2008-05-21
DK1922334T3 (da) 2011-04-18
CN101287755B (zh) 2014-12-31
SI1760089T1 (sl) 2009-12-31
DE602005016112D1 (de) 2009-10-01
PT1760089E (pt) 2009-10-19
BRPI0615466A2 (pt) 2011-05-17
CY1113062T1 (el) 2016-04-13
JP2009506762A (ja) 2009-02-19
ATE494303T1 (de) 2011-01-15
CY1110536T1 (el) 2015-04-29
KR20080052647A (ko) 2008-06-11
EP1922334B1 (en) 2011-01-05
EP1760089B1 (en) 2009-08-19
NZ565956A (en) 2011-06-30

Similar Documents

Publication Publication Date Title
UA97095C2 (ru) Противораковая вакцина, которая содержит опухолевоассоциированный пептид, который связывается с молекулами лейкоцитарного антигена человека (hla) класса i или ii, и ее применение в производстве лекарственного средства
WO2007028574A3 (en) Tumor-associated peptides binding promiscuously to human leukocyte antigen (hla) class ii molecules
WO2006037421A3 (en) Immunogenic t-helper epitopes from human tumour antigens and immunotherapeutic methods using said epitopes