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UA97536C2 - Proteasome inhibitors - Google Patents

Proteasome inhibitors

Info

Publication number
UA97536C2
UA97536C2 UAA201002409A UAA201002409A UA97536C2 UA 97536 C2 UA97536 C2 UA 97536C2 UA A201002409 A UAA201002409 A UA A201002409A UA A201002409 A UAA201002409 A UA A201002409A UA 97536 C2 UA97536 C2 UA 97536C2
Authority
UA
Ukraine
Prior art keywords
proteasome inhibitors
compositions
treatment
methods
various diseases
Prior art date
Application number
UAA201002409A
Other languages
English (en)
Ukrainian (uk)
Inventor
Эдвард Дж. Олхава
Михаэла Д. Данка
Original Assignee
Милленниум Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38691782&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA97536(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Милленниум Фармасьютикалз, Инк. filed Critical Милленниум Фармасьютикалз, Инк.
Publication of UA97536C2 publication Critical patent/UA97536C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

В данном изобретении предложены новые соединения, пригодные для применения как ингибиторы протеасом.В данном изобретении также предложены фармацевтические композиции, которые содержат соединения согласно данному изобретению, и применение указанных композиций для лечения разных заболеваний.
UAA201002409A 2007-08-06 2007-08-06 Proteasome inhibitors UA97536C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2007/017440 WO2009020448A1 (en) 2007-08-06 2007-08-06 Proteasome inhibitors

Publications (1)

Publication Number Publication Date
UA97536C2 true UA97536C2 (en) 2012-02-27

Family

ID=38691782

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201002409A UA97536C2 (en) 2007-08-06 2007-08-06 Proteasome inhibitors

Country Status (32)

Country Link
EP (3) EP2178888B1 (ru)
JP (1) JP5261488B2 (ru)
KR (6) KR20160040735A (ru)
CN (1) CN101772507B (ru)
AU (1) AU2007357338B2 (ru)
BR (1) BRPI0721905B8 (ru)
CA (1) CA2695082C (ru)
CY (2) CY1113386T1 (ru)
DK (1) DK2178888T3 (ru)
EA (1) EA028622B1 (ru)
EC (1) ECSP10010015A (ru)
ES (1) ES2390606T3 (ru)
FR (1) FR17C1011I2 (ru)
GE (1) GEP20125599B (ru)
HR (1) HRP20120745T1 (ru)
HU (1) HUS1700018I1 (ru)
IL (4) IL203641A (ru)
LT (1) LTC2178888I2 (ru)
LU (1) LUC00013I2 (ru)
MY (1) MY161991A (ru)
NL (1) NL300871I2 (ru)
NZ (1) NZ582693A (ru)
PH (1) PH12014500053B1 (ru)
PL (1) PL2178888T3 (ru)
PT (1) PT2178888E (ru)
RS (1) RS52435B (ru)
SG (1) SG10201508712QA (ru)
SI (1) SI2178888T1 (ru)
TN (1) TN2010000060A1 (ru)
UA (1) UA97536C2 (ru)
WO (1) WO2009020448A1 (ru)
ZA (1) ZA201000348B (ru)

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WO2007149512A2 (en) 2006-06-19 2007-12-27 Proteolix, Inc. Peptide epoxyketones for pr0teas0me inhibition
US7442830B1 (en) 2007-08-06 2008-10-28 Millenium Pharmaceuticals, Inc. Proteasome inhibitors
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AR075090A1 (es) 2008-09-29 2011-03-09 Millennium Pharm Inc Derivados de acido 1-amino-2-ciclobutiletilboronico inhibidores de proteosoma,utiles como agentes anticancerigenos, y composiciones farmaceuticas que los comprenden.
AU2009308516B2 (en) 2008-10-21 2016-08-25 Onyx Therapeutics, Inc. Combination therapy with peptide epoxyketones
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CN103570806B (zh) * 2012-07-26 2020-04-07 圣特莱国际公司 多肽环氧酮化合物
JP2013006855A (ja) * 2012-09-03 2013-01-10 Millennium Pharmaceuticals Inc プロテアソーム阻害剤
JP6018319B2 (ja) * 2012-12-03 2016-11-02 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 置換トリアゾールボロン酸化合物
US20160250238A1 (en) * 2013-10-03 2016-09-01 Millennium Pharmaceuticals, Inc. Method for the Prophylaxis or Treatment of Systemic Lupus Erythematosus and/or Lupus Nephritis
US20150335668A1 (en) 2014-05-20 2015-11-26 Millennium Pharmaceuticals, Inc. Method for cancer therapy
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WO2017198194A1 (zh) * 2016-05-19 2017-11-23 成都奥璟生物科技有限公司 一种硼酸和硼酸酯类化合物及其应用
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WO2018019196A1 (zh) * 2016-07-25 2018-02-01 深圳市塔吉瑞生物医药有限公司 一种取代的硼酸化合物及包含该化合物的药物组合物及其用途
CN108440583B (zh) * 2017-01-23 2020-12-04 成都奥璟生物科技有限公司 一种新的硼酸衍生物及其药物组合物
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CN109305980B (zh) * 2017-07-28 2022-10-11 成都奥璟生物科技有限公司 一种硼酸酯化合物、其合成方法及其用途
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Also Published As

Publication number Publication date
CY1113386T1 (el) 2016-06-22
EA201070247A1 (ru) 2010-06-30
CA2695082A1 (en) 2009-02-12
CY2017016I1 (el) 2017-07-12
LUC00013I2 (ru) 2017-06-19
SG10201508712QA (en) 2015-11-27
KR20150010802A (ko) 2015-01-28
EP2527347A1 (en) 2012-11-28
IL242290A0 (en) 2015-11-30
SI2178888T1 (sl) 2012-11-30
KR20160040735A (ko) 2016-04-14
KR20140042932A (ko) 2014-04-07
LUC00013I1 (ru) 2017-04-06
BRPI0721905A2 (pt) 2014-02-25
FR17C1011I1 (ru) 2017-05-26
ES2390606T3 (es) 2012-11-14
BRPI0721905B8 (pt) 2021-05-25
IL242292A0 (en) 2015-11-30
IL242291A0 (en) 2015-11-30
HUS1700018I1 (hu) 2017-05-29
KR101831674B1 (ko) 2018-02-23
EP3210987A1 (en) 2017-08-30
LTC2178888I2 (lt) 2018-03-12
ECSP10010015A (es) 2010-04-30
KR101474831B1 (ko) 2014-12-19
CA2695082C (en) 2015-07-28
LTPA2017010I1 (lt) 2017-05-10
HK1182924A1 (zh) 2013-12-13
EP2178888B1 (en) 2012-07-04
NZ582693A (en) 2012-01-12
IL242290A (en) 2017-12-31
PH12014500053A1 (en) 2015-03-30
HRP20120745T1 (hr) 2012-10-31
IL242292A (en) 2017-12-31
RS52435B (sr) 2013-02-28
JP2010535759A (ja) 2010-11-25
WO2009020448A1 (en) 2009-02-12
PT2178888E (pt) 2012-10-04
BRPI0721905B1 (pt) 2020-11-17
IL203641A (en) 2015-11-30
KR20170004031A (ko) 2017-01-10
ZA201000348B (en) 2011-03-30
CN101772507B (zh) 2012-12-12
PH12014500053B1 (en) 2015-03-30
IL242291A (en) 2017-12-31
CN101772507A (zh) 2010-07-07
KR20100059811A (ko) 2010-06-04
AU2007357338B2 (en) 2014-03-20
CY2017016I2 (el) 2017-07-12
TN2010000060A1 (en) 2011-09-26
EP2178888A1 (en) 2010-04-28
DK2178888T3 (da) 2012-10-01
JP5261488B2 (ja) 2013-08-14
NL300871I2 (nl) 2017-12-07
HK1143595A1 (en) 2011-01-07
EA028622B1 (ru) 2017-12-29
KR20140042933A (ko) 2014-04-07
GEP20125599B (en) 2012-08-10
PL2178888T3 (pl) 2012-11-30
FR17C1011I2 (fr) 2018-04-27
MY161991A (en) 2017-05-31
AU2007357338A1 (en) 2009-02-12

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