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UA97468C2 - Комбинация и фармацевтическая композиция, которая содержит 8-[3-аминопиперидин-1-ил]ксантины, способ ее получения и их применение в качестве лекарственного средства - Google Patents

Комбинация и фармацевтическая композиция, которая содержит 8-[3-аминопиперидин-1-ил]ксантины, способ ее получения и их применение в качестве лекарственного средства

Info

Publication number
UA97468C2
UA97468C2 UAA200800333A UAA200800333A UA97468C2 UA 97468 C2 UA97468 C2 UA 97468C2 UA A200800333 A UAA200800333 A UA A200800333A UA A200800333 A UAA200800333 A UA A200800333A UA 97468 C2 UA97468 C2 UA 97468C2
Authority
UA
Ukraine
Prior art keywords
combination
xanthines
piperidin
medicament
amino
Prior art date
Application number
UAA200800333A
Other languages
English (en)
Ukrainian (uk)
Inventor
Франк Химмельсбах
Эльке Лангкопф
Маттиас Экхардт
Михаель Марк
Роланд Майер
Рихард Херманн Лотц Ральф
Мохаммад Тадайон
Original Assignee
Бёрингер Ингельхайм Фарма Гмбх & Ко. Кг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бёрингер Ингельхайм Фарма Гмбх & Ко. Кг filed Critical Бёрингер Ингельхайм Фарма Гмбх & Ко. Кг
Publication of UA97468C2 publication Critical patent/UA97468C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

В заявке описана комбинация, которая содержит замещенные ксантины общей формулы (I)в которой R-Rимеют указанные в п. 1 формулы изобретения значения, их таутомеры, их стереоизомеры, их смеси или их соли, которые имеют ценные фармакологические свойства, прежде всего ингибирующее действие на активность дипептидилпептидазы-IV ( DPP-IV).
UAA200800333A 2002-08-21 2003-08-18 Комбинация и фармацевтическая композиция, которая содержит 8-[3-аминопиперидин-1-ил]ксантины, способ ее получения и их применение в качестве лекарственного средства UA97468C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10238243A DE10238243A1 (de) 2002-08-21 2002-08-21 8-[3-Amino-piperidin-1-yl]-xanthine, deren Herstellung und deren Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
UA97468C2 true UA97468C2 (ru) 2012-02-27

Family

ID=31197174

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200800333A UA97468C2 (ru) 2002-08-21 2003-08-18 Комбинация и фармацевтическая композиция, которая содержит 8-[3-аминопиперидин-1-ил]ксантины, способ ее получения и их применение в качестве лекарственного средства

Country Status (4)

Country Link
CN (2) CN101503409B (ru)
DE (1) DE10238243A1 (ru)
UA (1) UA97468C2 (ru)
ZA (1) ZA200500087B (ru)

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DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
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Also Published As

Publication number Publication date
CN101503408A (zh) 2009-08-12
CN101503409B (zh) 2014-01-22
DE10238243A1 (de) 2004-03-04
ZA200500087B (en) 2006-07-26
CN101503409A (zh) 2009-08-12
CN101503408B (zh) 2013-04-24

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