UA96282C2 - 3,5-substitgued piperidine compounds as renin inhibitors - Google Patents
3,5-substitgued piperidine compounds as renin inhibitorsInfo
- Publication number
- UA96282C2 UA96282C2 UAA200808524A UAA200808524A UA96282C2 UA 96282 C2 UA96282 C2 UA 96282C2 UA A200808524 A UAA200808524 A UA A200808524A UA A200808524 A UAA200808524 A UA A200808524A UA 96282 C2 UA96282 C2 UA 96282C2
- Authority
- UA
- Ukraine
- Prior art keywords
- treatment
- compound
- renin
- substituted piperidine
- disease
- Prior art date
Links
- 150000003053 piperidines Chemical class 0.000 title abstract 2
- 239000002461 renin inhibitor Substances 0.000 title 1
- 229940086526 renin-inhibitors Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 4
- 102100028255 Renin Human genes 0.000 abstract 3
- 108090000783 Renin Proteins 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 3
- -1 piperidine compound Chemical class 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N tetrahydropyridine hydrochloride Natural products C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to 3,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (= disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5-substituted piperidine compound, and/or a method of treatment comprising administering a 3,5-substituted piperidine compound, a method for the manufacture of a 3, 5-substituted piperidine compound, and novel intermediates and partial steps for its synthesis. The preferred compounds (which can also be present as salts) have the formula (I’), wherein R1 , R2, T, R3 and R4 are as defined in the specification., (I’)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05028771 | 2005-12-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA96282C2 true UA96282C2 (en) | 2011-10-25 |
Family
ID=40391423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200808524A UA96282C2 (en) | 2005-12-30 | 2006-12-28 | 3,5-substitgued piperidine compounds as renin inhibitors |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN101365680A (en) |
| TN (1) | TNSN08287A1 (en) |
| UA (1) | UA96282C2 (en) |
| ZA (1) | ZA200804956B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015156346A1 (en) * | 2014-04-10 | 2015-10-15 | 武田薬品工業株式会社 | Method for producing heterocyclic compound |
| CA3005707C (en) * | 2015-11-17 | 2023-11-21 | Aerie Pharmaceuticals, Inc. | Process for the preparation of kinase inhibitors and intermediates thereof |
| CN117865941B (en) * | 2024-03-13 | 2024-06-28 | 上海方予健康医药科技有限公司 | Substituted piperidine compounds, process for their preparation and their use |
-
2006
- 2006-12-28 UA UAA200808524A patent/UA96282C2/en unknown
- 2006-12-28 CN CNA200680051335XA patent/CN101365680A/en active Pending
-
2008
- 2008-06-06 ZA ZA200804956A patent/ZA200804956B/en unknown
- 2008-06-27 TN TNP2008000287A patent/TNSN08287A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TNSN08287A1 (en) | 2009-10-30 |
| ZA200804956B (en) | 2009-05-27 |
| CN101365680A (en) | 2009-02-11 |
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