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UA96265C2 - Композиция и способ ингибирования jak пути передачи сигнала - Google Patents

Композиция и способ ингибирования jak пути передачи сигнала

Info

Publication number
UA96265C2
UA96265C2 UAA200714921A UAA200714921A UA96265C2 UA 96265 C2 UA96265 C2 UA 96265C2 UA A200714921 A UAA200714921 A UA A200714921A UA A200714921 A UAA200714921 A UA A200714921A UA 96265 C2 UA96265 C2 UA 96265C2
Authority
UA
Ukraine
Prior art keywords
inhibition
composition
jak pathway
jak
pathway
Prior art date
Application number
UAA200714921A
Other languages
English (en)
Ukrainian (uk)
Inventor
Гуи Ли
Самбаиах Тота
Дейвид Керролл
Анкуш Аргейд
Кин Тсо
Арвиндер Срен
Джеффри Клоф
Хольгер Кеим
Сомасекхар БХАМИДИПАТИ
Ванесса Тейлор
Робин КУПЕР
Раджиндер Сингх
Брайан Вонг
Original Assignee
Райджел Фармасьютикалс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Райджел Фармасьютикалс, Инк. filed Critical Райджел Фармасьютикалс, Инк.
Publication of UA96265C2 publication Critical patent/UA96265C2/ru

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Данное изобретение касается соединения формулы, IIIAего сольвата или фармацевтически приемлемой соли, фармацевтической композиции на его основе, а также способа ингибирования активности JAK-киназы, особенно JAK3.
UAA200714921A 2005-06-08 2006-06-08 Композиция и способ ингибирования jak пути передачи сигнала UA96265C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68903205P 2005-06-08 2005-06-08

Publications (1)

Publication Number Publication Date
UA96265C2 true UA96265C2 (ru) 2011-10-25

Family

ID=40014879

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200714921A UA96265C2 (ru) 2005-06-08 2006-06-08 Композиция и способ ингибирования jak пути передачи сигнала

Country Status (3)

Country Link
CN (1) CN101282945A (ru)
UA (1) UA96265C2 (ru)
ZA (2) ZA200710206B (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8338439B2 (en) * 2008-06-27 2012-12-25 Celgene Avilomics Research, Inc. 2,4-disubstituted pyrimidines useful as kinase inhibitors
US8809343B2 (en) 2008-12-26 2014-08-19 Fudan University Pyrimidine derivative, preparation method and use thereof
CN102317265B (zh) * 2009-01-14 2015-03-25 里格尔药品股份有限公司 用于治疗炎性疾病的2,4-嘧啶二胺化合物
RU2672100C2 (ru) * 2010-07-28 2018-11-12 Райджел Фармасьютикалз, Инк. Композиции и способы ингибирования пути jak
CN103159749A (zh) * 2011-12-13 2013-06-19 南京友杰医药科技有限公司 抗抑郁药维拉佐酮（vilazodone）的合成方法
RU2641106C2 (ru) * 2013-10-16 2018-01-16 Фуджифилм Корпорэйшн Соль азотсодержащего гетероциклического соединения или ее кристаллическая форма, фармацевтическая композиция и ингибитор flt3
CN105924389A (zh) * 2015-12-18 2016-09-07 重庆两江药物研发中心有限公司 瑞戈非尼中间体的制备方法
CN110256465B (zh) * 2019-07-13 2021-08-13 南方医科大学 一种含二氢吡喃并噻唑的2,4-二氨基嘧啶及其应用
CN117402178B (zh) * 2023-12-15 2024-03-08 英矽智能科技(上海)有限公司 作为jak抑制剂和phd抑制剂的嘧啶类化合物
CN117756822B (zh) * 2023-12-20 2025-04-18 英矽智能科技(上海)有限公司 作为jak抑制剂和phd抑制剂的嘧啶氨基类化合物
CN120647626A (zh) * 2025-06-09 2025-09-16 江西省肿瘤医院(江西省第二人民医院、江西省癌症中心) 一种靶向egfr、axl靶点的4-氨基嘧啶类化合物及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0004888D0 (en) * 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds

Also Published As

Publication number Publication date
CN101282945A (zh) 2008-10-08
ZA200809949B (en) 2010-08-25
ZA200710206B (en) 2009-12-30

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