UA93036C2 - Лактамные соединения и применение в качестве фармацевтических препаратов - Google Patents
Лактамные соединения и применение в качестве фармацевтических препаратовInfo
- Publication number
- UA93036C2 UA93036C2 UAA200706357A UAA200706357A UA93036C2 UA 93036 C2 UA93036 C2 UA 93036C2 UA A200706357 A UAA200706357 A UA A200706357A UA A200706357 A UAA200706357 A UA A200706357A UA 93036 C2 UA93036 C2 UA 93036C2
- Authority
- UA
- Ukraine
- Prior art keywords
- pharmaceutical preparations
- lactam compounds
- diseases associated
- dehydrogenase type
- steroid dehydrogenase
- Prior art date
Links
- -1 Lactam compounds Chemical class 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 101710088194 Dehydrogenase Proteins 0.000 abstract 2
- 102000003979 Mineralocorticoid Receptors Human genes 0.000 abstract 2
- 108090000375 Mineralocorticoid Receptors Proteins 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- PQSUYGKTWSAVDQ-ZVIOFETBSA-N Aldosterone Chemical compound C([C@@]1([C@@H](C(=O)CO)CC[C@H]1[C@@H]1CC2)C=O)[C@H](O)[C@@H]1[C@]1(C)C2=CC(=O)CC1 PQSUYGKTWSAVDQ-ZVIOFETBSA-N 0.000 abstract 1
- PQSUYGKTWSAVDQ-UHFFFAOYSA-N Aldosterone Natural products C1CC2C3CCC(C(=O)CO)C3(C=O)CC(O)C2C2(C)C1=CC(=O)CC2 PQSUYGKTWSAVDQ-UHFFFAOYSA-N 0.000 abstract 1
- 229960002478 aldosterone Drugs 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Данное изобретение касается ингибиторов 11- -гидроксистероиддегидрогеназы 1-го типа, антагонистов минералокортикоидного рецептора (MR) и их фармацевтических композиций. Соединения согласно изобретению могут быть применены для лечения различных болезней, опосредствованных экспрессией или активностью 11--гидроксистероиддегидрогеназы 1-го типа, и/или болезней, ассоциированных с избытком альдостерона.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62661704P | 2004-11-10 | 2004-11-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA93036C2 true UA93036C2 (ru) | 2011-01-10 |
Family
ID=39012070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200706357A UA93036C2 (ru) | 2004-11-10 | 2005-11-09 | Лактамные соединения и применение в качестве фармацевтических препаратов |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN101098856A (ru) |
| CR (1) | CR9103A (ru) |
| UA (1) | UA93036C2 (ru) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102267995A (zh) * | 2010-06-04 | 2011-12-07 | 艾琪康医药科技（上海）有限公司 | 一种制备二氮杂螺环化合物的方法 |
-
2005
- 2005-11-09 CN CNA2005800459986A patent/CN101098856A/zh active Pending
- 2005-11-09 UA UAA200706357A patent/UA93036C2/ru unknown
-
2007
- 2007-05-03 CR CR9103A patent/CR9103A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101098856A (zh) | 2008-01-02 |
| CR9103A (es) | 2007-08-28 |
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