UA93036C2 - Lactam compounds and use thereof as pharmaceutical preparations - Google Patents
Lactam compounds and use thereof as pharmaceutical preparationsInfo
- Publication number
- UA93036C2 UA93036C2 UAA200706357A UAA200706357A UA93036C2 UA 93036 C2 UA93036 C2 UA 93036C2 UA A200706357 A UAA200706357 A UA A200706357A UA A200706357 A UAA200706357 A UA A200706357A UA 93036 C2 UA93036 C2 UA 93036C2
- Authority
- UA
- Ukraine
- Prior art keywords
- pharmaceutical preparations
- lactam compounds
- diseases associated
- dehydrogenase type
- steroid dehydrogenase
- Prior art date
Links
- -1 Lactam compounds Chemical class 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 101710088194 Dehydrogenase Proteins 0.000 abstract 2
- 102000003979 Mineralocorticoid Receptors Human genes 0.000 abstract 2
- 108090000375 Mineralocorticoid Receptors Proteins 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- PQSUYGKTWSAVDQ-ZVIOFETBSA-N Aldosterone Chemical compound C([C@@]1([C@@H](C(=O)CO)CC[C@H]1[C@@H]1CC2)C=O)[C@H](O)[C@@H]1[C@]1(C)C2=CC(=O)CC1 PQSUYGKTWSAVDQ-ZVIOFETBSA-N 0.000 abstract 1
- PQSUYGKTWSAVDQ-UHFFFAOYSA-N Aldosterone Natural products C1CC2C3CCC(C(=O)CO)C3(C=O)CC(O)C2C2(C)C1=CC(=O)CC2 PQSUYGKTWSAVDQ-UHFFFAOYSA-N 0.000 abstract 1
- 229960002478 aldosterone Drugs 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The present invention relates to inhibitors of 11-hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-hydroxyl steroid dehydrogenase type land/or diseases associated with aldosterone excess.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62661704P | 2004-11-10 | 2004-11-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA93036C2 true UA93036C2 (en) | 2011-01-10 |
Family
ID=39012070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200706357A UA93036C2 (en) | 2004-11-10 | 2005-11-09 | Lactam compounds and use thereof as pharmaceutical preparations |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN101098856A (en) |
| CR (1) | CR9103A (en) |
| UA (1) | UA93036C2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102267995A (en) * | 2010-06-04 | 2011-12-07 | 艾琪康医药科技（上海）有限公司 | Method for preparing diazaspiro compound |
-
2005
- 2005-11-09 CN CNA2005800459986A patent/CN101098856A/en active Pending
- 2005-11-09 UA UAA200706357A patent/UA93036C2/en unknown
-
2007
- 2007-05-03 CR CR9103A patent/CR9103A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101098856A (en) | 2008-01-02 |
| CR9103A (en) | 2007-08-28 |
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