GB2443377A - Anti-malarial composition comprising artesunate and lumefantrine - Google Patents
Anti-malarial composition comprising artesunate and lumefantrineInfo
- Publication number
- GB2443377A GB2443377A GB0804039A GB0804039A GB2443377A GB 2443377 A GB2443377 A GB 2443377A GB 0804039 A GB0804039 A GB 0804039A GB 0804039 A GB0804039 A GB 0804039A GB 2443377 A GB2443377 A GB 2443377A
- Authority
- GB
- United Kingdom
- Prior art keywords
- lumefantrine
- artesunate
- composition
- malarial composition
- malarial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- FIHJKUPKCHIPAT-AHIGJZGOSA-N artesunate Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2O[C@@H](OC(=O)CCC(O)=O)[C@@H]4C FIHJKUPKCHIPAT-AHIGJZGOSA-N 0.000 title abstract 2
- 229960004991 artesunate Drugs 0.000 title abstract 2
- DYLGFOYVTXJFJP-MYYYXRDXSA-N lumefantrine Chemical compound C12=CC(Cl)=CC=C2C=2C(C(O)CN(CCCC)CCCC)=CC(Cl)=CC=2\C1=C/C1=CC=C(Cl)C=C1 DYLGFOYVTXJFJP-MYYYXRDXSA-N 0.000 title abstract 2
- 229960004985 lumefantrine Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000000078 anti-malarial effect Effects 0.000 title 1
- 239000003430 antimalarial agent Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 201000004792 malaria Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A pharmaceutical composition comprising artesunate and lumefantrine provided in combination in a single pharmaceutical dosage unit. The invention also relates to a method of making the pharmaceutical composition, and to the use of the composition in the treatment of malaria.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN794MU2005 | 2005-08-05 | ||
| PCT/GB2006/002919 WO2007017646A2 (en) | 2005-08-05 | 2006-08-04 | Anti-malarial composition comprising artesunate and lumefantrine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB0804039D0 GB0804039D0 (en) | 2008-04-09 |
| GB2443377A true GB2443377A (en) | 2008-04-30 |
Family
ID=37649482
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0804039A Withdrawn GB2443377A (en) | 2005-08-05 | 2008-03-04 | Anti-malarial composition comprising artesunate and lumefantrine |
Country Status (3)
| Country | Link |
|---|---|
| GB (1) | GB2443377A (en) |
| WO (1) | WO2007017646A2 (en) |
| ZA (1) | ZA200801208B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH696229A5 (en) * | 2006-05-13 | 2007-02-28 | Professeur Dr Achille Benakis | New galenic forms of Artemisinin and its derivatives in combination with other antimalarials for the treatment of malaria. |
| FR2914860B1 (en) * | 2007-04-12 | 2009-05-22 | Ile D Inventeurs Apis Spheromo | MULTILAYER SPHEROIDS WITH ANTIPALUDITIC ACTION IN WHICH ONE OF THE LAYERS CONTAINS ARTESUNATE |
| WO2010004573A1 (en) * | 2008-07-07 | 2010-01-14 | Ipca Laboratories Limited | Synergistic antimalarial pharmaceutical composition |
| WO2011009956A1 (en) * | 2009-07-24 | 2011-01-27 | Dafra Pharma N.V. | Injectable aqueous solution containing artesunate |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992002217A1 (en) * | 1990-08-08 | 1992-02-20 | Ciba-Geigy Ag | Antimalarial compositions |
-
2006
- 2006-08-04 WO PCT/GB2006/002919 patent/WO2007017646A2/en not_active Ceased
-
2008
- 2008-02-04 ZA ZA200801208A patent/ZA200801208B/en unknown
- 2008-03-04 GB GB0804039A patent/GB2443377A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992002217A1 (en) * | 1990-08-08 | 1992-02-20 | Ciba-Geigy Ag | Antimalarial compositions |
Non-Patent Citations (2)
| Title |
|---|
| "Independent Review of Medicines for malaria venture" DFID Helath Resource Centre, {Online], 31 May 2005, pp.1-28, London, UK. Retrieved from the internet; URL: <http://www.mmv.org/IMG/pdf/MMV_Final_Report_7.7.05.pdf> * |
| RATIONAL PHARMACEUTICAL MANAGMENT PLUS, [Online], 31 May 2005, KABUYA-MUTSHIPAYI, pp.1-11. Retrieved from the internet: URL<:http://pdf.dec.org/pdf_docs/PDACF086.pdf> * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007017646A2 (en) | 2007-02-15 |
| WO2007017646A3 (en) | 2007-04-19 |
| ZA200801208B (en) | 2009-05-27 |
| GB0804039D0 (en) | 2008-04-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |