UA91996C2 - Производные стильбена и их применение для связывания и визуализации амилоидных бляшек - Google Patents
Производные стильбена и их применение для связывания и визуализации амилоидных бляшекInfo
- Publication number
- UA91996C2 UA91996C2 UAA200708065A UAA200708065A UA91996C2 UA 91996 C2 UA91996 C2 UA 91996C2 UA A200708065 A UAA200708065 A UA A200708065A UA A200708065 A UAA200708065 A UA A200708065A UA 91996 C2 UA91996 C2 UA 91996C2
- Authority
- UA
- Ukraine
- Prior art keywords
- binding
- amyloid plaques
- stilbene derivatives
- imaging amyloid
- amyloid deposits
- Prior art date
Links
- 208000037259 Amyloid Plaque Diseases 0.000 title abstract 5
- 238000003384 imaging method Methods 0.000 title abstract 3
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical class C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 4
- 102000009091 Amyloidogenic Proteins Human genes 0.000 abstract 1
- 108010048112 Amyloidogenic Proteins Proteins 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Данное изобретение касается способа визуализации амилоидных отложений меченых соединений и способов получения меченых соединений, которые используются для визуализации амилоидных отложений. Данное изобретение также касается соединений и способов получения соединений для ингибирования агрегации амилоидных белков, которые образовывают амилоидные отложения, и способов доставки терапевтического агента к амилоидным белкам.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63669604P | 2004-12-17 | 2004-12-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA91996C2 true UA91996C2 (ru) | 2010-09-27 |
Family
ID=39085994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200708065A UA91996C2 (ru) | 2004-12-17 | 2005-12-19 | Производные стильбена и их применение для связывания и визуализации амилоидных бляшек |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN101123995B (ru) |
| CR (1) | CR9206A (ru) |
| UA (1) | UA91996C2 (ru) |
| ZA (1) | ZA200705104B (ru) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102471177A (zh) * | 2009-07-10 | 2012-05-23 | 拜耳医药股份有限公司 | 低至中压液相色谱在放射性示踪剂纯化中的应用 |
| US20120328521A1 (en) * | 2009-12-23 | 2012-12-27 | Piramal Imaging Sa | Formulations suitable for pet imaging with hydrophobic pet agents |
| TW201906818A (zh) * | 2017-05-31 | 2019-02-16 | 美商５１１製藥公司 | 新穎氘取代之正子發射斷層掃描（ｐｅｔ）顯影劑及其藥理應用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD231432A1 (de) * | 1984-11-01 | 1985-12-24 | Univ Leipzig | Material zur silberfreien bildaufzeichnung |
| EP1432453B1 (en) * | 2001-08-27 | 2013-08-14 | The Trustees of The University of Pennsylvania | Stilbene derivatives and their use for binding and imaging amyloid plaques |
-
2005
- 2005-12-19 UA UAA200708065A patent/UA91996C2/ru unknown
- 2005-12-19 CN CN2005800484422A patent/CN101123995B/zh not_active Expired - Lifetime
-
2007
- 2007-06-15 ZA ZA200705104A patent/ZA200705104B/xx unknown
- 2007-06-25 CR CR9206A patent/CR9206A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CR9206A (es) | 2009-12-30 |
| CN101123995A (zh) | 2008-02-13 |
| ZA200705104B (en) | 2008-09-25 |
| CN101123995B (zh) | 2011-11-16 |
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