UA91996C2 - Stilbene derivatives and their use for binding and imaging amyloid plaques - Google Patents
Stilbene derivatives and their use for binding and imaging amyloid plaquesInfo
- Publication number
- UA91996C2 UA91996C2 UAA200708065A UAA200708065A UA91996C2 UA 91996 C2 UA91996 C2 UA 91996C2 UA A200708065 A UAA200708065 A UA A200708065A UA A200708065 A UAA200708065 A UA A200708065A UA 91996 C2 UA91996 C2 UA 91996C2
- Authority
- UA
- Ukraine
- Prior art keywords
- binding
- amyloid plaques
- stilbene derivatives
- imaging amyloid
- amyloid deposits
- Prior art date
Links
- 208000037259 Amyloid Plaque Diseases 0.000 title abstract 5
- 238000003384 imaging method Methods 0.000 title abstract 3
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical class C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 4
- 102000009091 Amyloidogenic Proteins Human genes 0.000 abstract 1
- 108010048112 Amyloidogenic Proteins Proteins 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making com-pounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63669604P | 2004-12-17 | 2004-12-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA91996C2 true UA91996C2 (en) | 2010-09-27 |
Family
ID=39085994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200708065A UA91996C2 (en) | 2004-12-17 | 2005-12-19 | Stilbene derivatives and their use for binding and imaging amyloid plaques |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN101123995B (en) |
| CR (1) | CR9206A (en) |
| UA (1) | UA91996C2 (en) |
| ZA (1) | ZA200705104B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102471177A (en) * | 2009-07-10 | 2012-05-23 | 拜耳医药股份有限公司 | Usage of low to medium-pressure liquid chromatography for the purification of radiotracers |
| US20120328521A1 (en) * | 2009-12-23 | 2012-12-27 | Piramal Imaging Sa | Formulations suitable for pet imaging with hydrophobic pet agents |
| TW201906818A (en) * | 2017-05-31 | 2019-02-16 | 美商511製藥公司 | Novel erbium-substituted positron emission tomography (PET) developer and its pharmacological application |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD231432A1 (en) * | 1984-11-01 | 1985-12-24 | Univ Leipzig | MATERIAL FOR SILVER-FREE IMAGE RECORDING |
| EP1432453B1 (en) * | 2001-08-27 | 2013-08-14 | The Trustees of The University of Pennsylvania | Stilbene derivatives and their use for binding and imaging amyloid plaques |
-
2005
- 2005-12-19 UA UAA200708065A patent/UA91996C2/en unknown
- 2005-12-19 CN CN2005800484422A patent/CN101123995B/en not_active Expired - Lifetime
-
2007
- 2007-06-15 ZA ZA200705104A patent/ZA200705104B/en unknown
- 2007-06-25 CR CR9206A patent/CR9206A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CR9206A (en) | 2009-12-30 |
| CN101123995A (en) | 2008-02-13 |
| ZA200705104B (en) | 2008-09-25 |
| CN101123995B (en) | 2011-11-16 |
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