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UA88444C2 - Aza spiro alkane derivatives as inhibitors of metallproteases - Google Patents

Aza spiro alkane derivatives as inhibitors of metallproteases

Info

Publication number
UA88444C2
UA88444C2 UAA200511110A UAA200511110A UA88444C2 UA 88444 C2 UA88444 C2 UA 88444C2 UA A200511110 A UAA200511110 A UA A200511110A UA A200511110 A UAA200511110 A UA A200511110A UA 88444 C2 UA88444 C2 UA 88444C2
Authority
UA
Ukraine
Prior art keywords
metallproteases
inhibitors
formula
alkane derivatives
aza spiro
Prior art date
Application number
UAA200511110A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Веньцин Яо
Цзиньцун Чжо
Мейчжун Ксу
Фенлей Чжан
Брайан Меткаф
Original Assignee
Инсайт Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37390761&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA88444(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Инсайт Корпорейшн filed Critical Инсайт Корпорейшн
Publication of UA88444C2 publication Critical patent/UA88444C2/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention provides a compound of Formula I or Formula II: enantiomer, diastereomer, prodrug, solvate, metabolite, or pharmaceutically acceptable salt thereof, wherein constituent variables are provided herein. The compounds of Formula (I) and (II) are modulators of metalloproteases and are useful in treating diseases associated with metalloprotease activity such as arthritis, cancer, cardiovascular disorders, skin disorders, inflammation and allergic conditions.III
UAA200511110A 2003-04-24 2004-04-23 Aza spiro alkane derivatives as inhibitors of metallproteases UA88444C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46615903P 2003-04-24 2003-04-24

Publications (1)

Publication Number Publication Date
UA88444C2 true UA88444C2 (en) 2009-10-26

Family

ID=37390761

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200511110A UA88444C2 (en) 2003-04-24 2004-04-23 Aza spiro alkane derivatives as inhibitors of metallproteases

Country Status (4)

Country Link
CN (1) CN1863532A (en)
CR (1) CR8045A (en)
UA (1) UA88444C2 (en)
ZA (1) ZA200509496B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11851475B2 (en) 2018-01-03 2023-12-26 Xi'an Jiaotong-Liverpool University Membrane-type metalloprotease inhibitory protein and pharmaceutical and pharmaceutical composition containing same, and respective uses thereof
CN109394786A (en) * 2018-10-26 2019-03-01 西交利物浦大学 A kind of antitumor medicine composition

Also Published As

Publication number Publication date
CN1863532A (en) 2006-11-15
ZA200509496B (en) 2006-10-25
CR8045A (en) 2006-05-29

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