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UA86629C2 - Oral sustained release formulation of tedisamil with gastric retention properties - Google Patents

Oral sustained release formulation of tedisamil with gastric retention properties

Info

Publication number
UA86629C2
UA86629C2 UAA200700949A UAA200700949A UA86629C2 UA 86629 C2 UA86629 C2 UA 86629C2 UA A200700949 A UAA200700949 A UA A200700949A UA A200700949 A UAA200700949 A UA A200700949A UA 86629 C2 UA86629 C2 UA 86629C2
Authority
UA
Ukraine
Prior art keywords
tedisamil
sustained release
release formulation
retention properties
gastric retention
Prior art date
Application number
UAA200700949A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Йоган Баккер
Винтер Мариус Л. де
Санта Фабиано
Original Assignee
Сольве Фармасьютикалз Б.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сольве Фармасьютикалз Б.В. filed Critical Сольве Фармасьютикалз Б.В.
Publication of UA86629C2 publication Critical patent/UA86629C2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to a novel sustained release formulation with gastric retention properties comprising tedisamil 5 to 40 wt % of tedisamil or a pharmaceutically acceptable salt thereof, 30 to 85 wt % of a hydroswelling polymer matrix and 2.5 to 5 wt % of a salt being capable of releasing gaseous carbon dioxide in a gastric environment, process for the preparation thereof and the use of this formulation in the prevention and treatment of atrial fibrillation, atrial flutter and cardiac ischemia.
UAA200700949A 2004-06-28 2005-06-27 Oral sustained release formulation of tedisamil with gastric retention properties UA86629C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04102987 2004-06-28

Publications (1)

Publication Number Publication Date
UA86629C2 true UA86629C2 (en) 2009-05-12

Family

ID=34929254

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200700949A UA86629C2 (en) 2004-06-28 2005-06-27 Oral sustained release formulation of tedisamil with gastric retention properties

Country Status (5)

Country Link
CN (1) CN1976683B (en)
AR (1) AR049936A1 (en)
BR (1) BRPI0512671A (en)
TW (1) TW200603793A (en)
UA (1) UA86629C2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109602714B (en) * 2018-12-29 2020-06-12 广东中润药物研发有限公司 A kind of rivaroxaban gastric retention tablet and preparation method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1466451B (en) * 2000-09-29 2010-05-12 索尔瓦药物有限公司 Sustained-release pharmaceutical formulations independent of ionic strength

Also Published As

Publication number Publication date
AR049936A1 (en) 2006-09-13
BRPI0512671A (en) 2008-04-01
CN1976683A (en) 2007-06-06
TW200603793A (en) 2006-02-01
CN1976683B (en) 2010-10-06

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