MXPA06000796A - Use of 3,7-diazabicyclo`3, 3,1 !nonane compounds for the treatment and/or prophylaxis of anti-arrhythmic events in male human patients. - Google Patents
Use of 3,7-diazabicyclo`3, 3,1 !nonane compounds for the treatment and/or prophylaxis of anti-arrhythmic events in male human patients.Info
- Publication number
- MXPA06000796A MXPA06000796A MXPA06000796A MXPA06000796A MXPA06000796A MX PA06000796 A MXPA06000796 A MX PA06000796A MX PA06000796 A MXPA06000796 A MX PA06000796A MX PA06000796 A MXPA06000796 A MX PA06000796A MX PA06000796 A MXPA06000796 A MX PA06000796A
- Authority
- MX
- Mexico
- Prior art keywords
- diazabicyclo
- human patients
- prophylaxis
- male human
- treatment
- Prior art date
Links
- 230000003288 anthiarrhythmic effect Effects 0.000 title abstract 2
- 239000003416 antiarrhythmic agent Substances 0.000 title abstract 2
- BKIMMITUMNQMOS-UHFFFAOYSA-N nonane Chemical class CCCCCCCCC BKIMMITUMNQMOS-UHFFFAOYSA-N 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- 206010003658 Atrial Fibrillation Diseases 0.000 abstract 2
- PTPQJKANBKHDPM-UHFFFAOYSA-N 3,7-diazabicyclo[3.3.1]nonane Chemical class C1NCC2CNCC1C2 PTPQJKANBKHDPM-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000033764 rhythmic process Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- CTIRHWCPXYGDGF-HDICACEKSA-N tedisamil Chemical compound [H][C@]12CN(CC3CC3)C[C@]([H])(CN(CC3CC3)C1)C21CCCC1 CTIRHWCPXYGDGF-HDICACEKSA-N 0.000 abstract 1
- 229960002926 tedisamil Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
The present invention relates to the use of 3,7-diazabicyclo[3,3,1]nonane compounds, preferably of 9,9-alkylene-3,7 -diazabicyclo[3,3,1]nonane compounds, and most preferably to the use of tedisamil, and the physiologically acceptable acid addition salts and/or solvates thereof, for the treatment and/or prophylaxis of anti-arrhythmic events in male human patients, preferably in conversion of recent onset of atrial fibrillation (Afib) or flutter to normal sinus rhythm (NSR) in male human patients.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03102243 | 2003-07-21 | ||
| PCT/EP2004/051532 WO2005011690A1 (en) | 2003-07-21 | 2004-07-19 | Use of 3,7-diazabicyclo`3, 3,1 !nonane compounds for the treatment and/or prophylaxis of anti-arrhythmic events in male human patients |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA06000796A true MXPA06000796A (en) | 2006-04-07 |
Family
ID=34112472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA06000796A MXPA06000796A (en) | 2003-07-21 | 2004-07-19 | Use of 3,7-diazabicyclo`3, 3,1 !nonane compounds for the treatment and/or prophylaxis of anti-arrhythmic events in male human patients. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1648456A1 (en) |
| JP (1) | JP2006528155A (en) |
| CN (1) | CN1822833A (en) |
| AU (1) | AU2004260624A1 (en) |
| BR (1) | BRPI0412247A (en) |
| CA (1) | CA2533492A1 (en) |
| MX (1) | MXPA06000796A (en) |
| WO (1) | WO2005011690A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2707361T3 (en) | 2011-05-10 | 2018-01-31 | Gilead Sciences Inc | Fused heterocyclic compounds as sodium channel modulators |
| TWI549944B (en) | 2011-07-01 | 2016-09-21 | 吉李德科學股份有限公司 | Fused heterocyclic compound as ion channel regulator |
| NO3175985T3 (en) | 2011-07-01 | 2018-04-28 | ||
| WO2014134419A1 (en) * | 2013-03-01 | 2014-09-04 | Gilead Sciences, Inc. | Use of ikach blockers for the treatment of cardiac diseases |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3234697A1 (en) * | 1982-09-18 | 1984-03-22 | Kali-Chemie Pharma Gmbh, 3000 Hannover | NEW DIAZABICYCLO (3,3,1) NONANA |
| PT88381B (en) * | 1987-09-09 | 1995-07-06 | Kali Chemie Pharma Gmbh | PROCESS FOR THE PREPARATION OF NEW COMPOUNDS 3,7-DIAZABICYCLO (3,3,1) NONANO, AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS |
| DE4139763A1 (en) * | 1991-12-03 | 1993-06-09 | Kali-Chemie Pharma Gmbh, 3000 Hannover, De | CRYSTALLINE FUMAR ACID SALTS OF 9,9-ALKYLENE-3,7-DIAZABICYCLONONAN COMPOUNDS AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
| TW200418468A (en) * | 2002-11-18 | 2004-10-01 | Solvay Pharm Gmbh | Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events |
-
2004
- 2004-07-19 EP EP04742001A patent/EP1648456A1/en not_active Withdrawn
- 2004-07-19 MX MXPA06000796A patent/MXPA06000796A/en not_active Application Discontinuation
- 2004-07-19 JP JP2006520832A patent/JP2006528155A/en not_active Withdrawn
- 2004-07-19 WO PCT/EP2004/051532 patent/WO2005011690A1/en not_active Ceased
- 2004-07-19 CN CNA200480019884XA patent/CN1822833A/en active Pending
- 2004-07-19 AU AU2004260624A patent/AU2004260624A1/en not_active Abandoned
- 2004-07-19 BR BRPI0412247-0A patent/BRPI0412247A/en not_active Application Discontinuation
- 2004-07-19 CA CA002533492A patent/CA2533492A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN1822833A (en) | 2006-08-23 |
| BRPI0412247A (en) | 2006-09-19 |
| CA2533492A1 (en) | 2005-02-10 |
| AU2004260624A1 (en) | 2005-02-10 |
| JP2006528155A (en) | 2006-12-14 |
| EP1648456A1 (en) | 2006-04-26 |
| WO2005011690A1 (en) | 2005-02-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |