UA83233C2 - Замещенный 2-аминотетралин для лечения депрессии - Google Patents
Замещенный 2-аминотетралин для лечения депрессииInfo
- Publication number
- UA83233C2 UA83233C2 UAA200600562A UAA200600562A UA83233C2 UA 83233 C2 UA83233 C2 UA 83233C2 UA A200600562 A UAA200600562 A UA A200600562A UA A200600562 A UAA200600562 A UA A200600562A UA 83233 C2 UA83233 C2 UA 83233C2
- Authority
- UA
- Ukraine
- Prior art keywords
- depression
- aminotetralin
- substituted
- treatment
- entiomers
- Prior art date
Links
- LCGFVWKNXLRFIF-UHFFFAOYSA-N 1,2,3,4-tetrahydronaphthalen-2-amine Chemical class C1=CC=C2CC(N)CCC2=C1 LCGFVWKNXLRFIF-UHFFFAOYSA-N 0.000 title 1
- 208000020401 Depressive disease Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
Изобретение касается применения соединения общей формулы І, его фармацевтически приемлемых солей, рацематов или чистых энантиомеров для получения медикамента, который используют для лечения депрессии. Заместители определены в описании.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10334187A DE10334187A1 (de) | 2003-07-26 | 2003-07-26 | Substituierte 2-Aminotetraline zur Behandlung von Depressionen |
| PCT/EP2004/008169 WO2005009425A1 (de) | 2003-07-26 | 2004-07-22 | Substituierte 2-aminotetraline zur behandlung von depressionen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA83233C2 true UA83233C2 (ru) | 2008-06-25 |
Family
ID=34088861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200600562A UA83233C2 (ru) | 2003-07-26 | 2004-07-22 | Замещенный 2-аминотетралин для лечения депрессии |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20070072917A1 (ru) |
| EP (1) | EP1648433B1 (ru) |
| JP (1) | JP2007500155A (ru) |
| KR (1) | KR101160699B1 (ru) |
| CN (1) | CN1832734B (ru) |
| AT (1) | ATE373474T1 (ru) |
| AU (1) | AU2004258698A1 (ru) |
| BR (1) | BRPI0412999A (ru) |
| CA (1) | CA2532804C (ru) |
| DE (2) | DE10334187A1 (ru) |
| EA (1) | EA009870B1 (ru) |
| ES (1) | ES2291914T3 (ru) |
| IL (1) | IL173062A (ru) |
| IS (1) | IS2696B (ru) |
| MX (1) | MXPA06000865A (ru) |
| NO (1) | NO20060847L (ru) |
| UA (1) | UA83233C2 (ru) |
| WO (1) | WO2005009425A1 (ru) |
| ZA (1) | ZA200600343B (ru) |
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| DE10041479A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923 |
| DE10041478A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
| US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
| US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
| US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
| DE10234673B4 (de) * | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
| US8211462B2 (en) | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
| US8246980B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
| SI1426049T1 (en) | 2002-12-02 | 2005-08-31 | Sanol Arznei Schwarz Gmbh | Iontophoretic delivery of rotigotine for the treatment of Parkinson's disease |
| DE10261696A1 (de) | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
| DE10334188B4 (de) * | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
| DE10359528A1 (de) * | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
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| EP1976495A2 (en) * | 2006-01-06 | 2008-10-08 | Aarhus Universitet | Compounds acting on the serotonin transporter |
| DE102006006532B4 (de) | 2006-02-10 | 2007-11-08 | Biogenerics Pharma Gmbh | Pharmazeutische Zubereitung |
| TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
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| PT3257504T (pt) | 2009-12-22 | 2024-09-03 | Ucb Biopharma Sprl | Polivinilpirrolidona para a estabilização de uma dispersão sólida da forma não cristalina de rotigotina |
| CN103768010B (zh) * | 2012-10-22 | 2016-05-25 | 苏州药明康德新药开发股份有限公司 | 采用磺丁基-β-环糊精配制高浓度四氢化萘类化合物均一稳定溶液的方法 |
| CN103768043B (zh) * | 2012-10-22 | 2015-12-09 | 苏州药明康德新药开发股份有限公司 | 采用羟丙基-β-环糊精配制四氢化萘类化合物均一稳定溶液的方法 |
| WO2022089408A1 (zh) * | 2020-10-27 | 2022-05-05 | 广州市恒诺康医药科技有限公司 | 四氢萘类化合物、其药物组合物及其用途 |
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| JP2007518754A (ja) * | 2004-01-22 | 2007-07-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | モノアミン神経伝達物質再取込みインヒビターとドーパミンアゴニストを含む医薬組成物 |
| US20050197385A1 (en) * | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
| TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
| AU2008328920B2 (en) * | 2007-11-28 | 2013-09-12 | Ucb Pharma Gmbh | Polymorphic form of Rotigotine |
| EP2281559A1 (en) * | 2009-06-26 | 2011-02-09 | UCB Pharma GmbH | Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis |
| PT3257504T (pt) * | 2009-12-22 | 2024-09-03 | Ucb Biopharma Sprl | Polivinilpirrolidona para a estabilização de uma dispersão sólida da forma não cristalina de rotigotina |
-
2003
- 2003-07-26 DE DE10334187A patent/DE10334187A1/de not_active Ceased
-
2004
- 2004-07-22 EP EP04763387A patent/EP1648433B1/de not_active Expired - Lifetime
- 2004-07-22 CA CA2532804A patent/CA2532804C/en not_active Expired - Fee Related
- 2004-07-22 KR KR1020067001812A patent/KR101160699B1/ko not_active Expired - Fee Related
- 2004-07-22 AU AU2004258698A patent/AU2004258698A1/en not_active Abandoned
- 2004-07-22 WO PCT/EP2004/008169 patent/WO2005009425A1/de not_active Ceased
- 2004-07-22 US US10/565,713 patent/US20070072917A1/en not_active Abandoned
- 2004-07-22 DE DE502004005033T patent/DE502004005033D1/de not_active Expired - Lifetime
- 2004-07-22 CN CN2004800216477A patent/CN1832734B/zh not_active Expired - Fee Related
- 2004-07-22 AT AT04763387T patent/ATE373474T1/de not_active IP Right Cessation
- 2004-07-22 JP JP2006521477A patent/JP2007500155A/ja active Pending
- 2004-07-22 BR BRPI0412999-7A patent/BRPI0412999A/pt not_active IP Right Cessation
- 2004-07-22 ES ES04763387T patent/ES2291914T3/es not_active Expired - Lifetime
- 2004-07-22 UA UAA200600562A patent/UA83233C2/ru unknown
- 2004-07-22 MX MXPA06000865A patent/MXPA06000865A/es active IP Right Grant
- 2004-07-22 EA EA200600223A patent/EA009870B1/ru not_active IP Right Cessation
-
2006
- 2006-01-10 IL IL173062A patent/IL173062A/en not_active IP Right Cessation
- 2006-01-10 ZA ZA200600343A patent/ZA200600343B/xx unknown
- 2006-01-12 IS IS8230A patent/IS2696B/is unknown
- 2006-02-21 NO NO20060847A patent/NO20060847L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EA200600223A1 (ru) | 2006-08-25 |
| ES2291914T3 (es) | 2008-03-01 |
| CN1832734B (zh) | 2010-09-29 |
| IS2696B (is) | 2010-11-15 |
| IL173062A (en) | 2011-12-29 |
| EA009870B1 (ru) | 2008-04-28 |
| HK1091121A1 (en) | 2007-01-12 |
| EP1648433B1 (de) | 2007-09-19 |
| NO20060847L (no) | 2006-02-21 |
| CN1832734A (zh) | 2006-09-13 |
| ZA200600343B (en) | 2006-11-29 |
| WO2005009425A1 (de) | 2005-02-03 |
| US20070072917A1 (en) | 2007-03-29 |
| EP1648433A1 (de) | 2006-04-26 |
| IS8230A (is) | 2006-01-12 |
| JP2007500155A (ja) | 2007-01-11 |
| KR101160699B1 (ko) | 2012-06-28 |
| BRPI0412999A (pt) | 2006-10-03 |
| ATE373474T1 (de) | 2007-10-15 |
| IL173062A0 (en) | 2006-06-11 |
| DE10334187A1 (de) | 2005-03-03 |
| AU2004258698A1 (en) | 2005-02-03 |
| CA2532804A1 (en) | 2005-02-03 |
| DE502004005033D1 (de) | 2007-10-31 |
| KR20060052898A (ko) | 2006-05-19 |
| CA2532804C (en) | 2012-09-25 |
| MXPA06000865A (es) | 2006-05-04 |
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