UA82297C2 - Benzimidazolone carboxylic acid derivatives - Google Patents
Benzimidazolone carboxylic acid derivatives Download PDFInfo
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- UA82297C2 UA82297C2 UAA200613251A UAA200613251A UA82297C2 UA 82297 C2 UA82297 C2 UA 82297C2 UA A200613251 A UAA200613251 A UA A200613251A UA A200613251 A UAA200613251 A UA A200613251A UA 82297 C2 UA82297 C2 UA 82297C2
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- UA
- Ukraine
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- stage
- carbon atoms
- methyl
- isopropyl
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- -1 Benzimidazolone carboxylic acid derivatives Chemical class 0.000 title claims description 137
- 150000001875 compounds Chemical class 0.000 claims abstract description 278
- 150000003839 salts Chemical class 0.000 claims abstract description 45
- 239000012453 solvate Substances 0.000 claims abstract description 30
- 230000000694 effects Effects 0.000 claims abstract description 20
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- 238000011282 treatment Methods 0.000 claims abstract description 13
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- 230000001404 mediated effect Effects 0.000 claims abstract description 7
- 208000024827 Alzheimer disease Diseases 0.000 claims abstract description 6
- 208000024172 Cardiovascular disease Diseases 0.000 claims abstract description 6
- 206010010774 Constipation Diseases 0.000 claims abstract description 6
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- 125000004432 carbon atom Chemical group C* 0.000 claims description 137
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 130
- 238000000034 method Methods 0.000 claims description 110
- 125000002947 alkylene group Chemical group 0.000 claims description 49
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- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 34
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Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Данное изобретение касается соединений формулы (І): где каждый из символов R, R, R, А и m отвечает описанному в данной заявке, или их фармацевтически приемлемых солей и сольватов, а также композиций, содержащих такие соединения, и применению таких соединений при лечении состояний, опосредованных активностью рецептора 5-НТ, таких как, не ограничиваясь перечисленными, гастроэзофагальное рефлюксное заболевание, желудочно-кишечные заболевания, расстройства перистальтики желудка, неязвенная диспепсия, функциональная диспесия, синдром раздраженного желудка (IBS), запор, диспепсия, эзофагит, гастроэзофагальные заболевания, тошнота, заболевания центральной нервной системы, заболевание Альцгеймера, расстройства познавательной способности, рвота, мигрень, неврологические заболевания, боль, се�
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004177488A JP4129445B2 (ja) | 2004-06-15 | 2004-06-15 | ベンズイミダゾロンカルボン酸誘導体 |
| US60703504P | 2004-09-02 | 2004-09-02 | |
| PCT/IB2005/001825 WO2005123718A2 (en) | 2004-06-15 | 2005-06-01 | Benzimidazolone carboxylic acid derivatives |
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| Publication Number | Publication Date |
|---|---|
| UA82297C2 true UA82297C2 (en) | 2008-03-25 |
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| Application Number | Title | Priority Date | Filing Date |
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| UAA200613251A UA82297C2 (en) | 2004-06-15 | 2005-01-06 | Benzimidazolone carboxylic acid derivatives |
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| Country | Link |
|---|---|
| UA (1) | UA82297C2 (ru) |
-
2005
- 2005-01-06 UA UAA200613251A patent/UA82297C2/uk unknown
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