TWI422811B - Portable biochemical detection device - Google Patents

Description

Portable biochemical detection device

The invention relates to a portable biochemical detecting device, which has the advantages of a simple portable device, a spherical pivoting portion with multi-directional deflection detection, a spherical pivoting portion and a working rotating disc, and the like. .

Traditional specimen detection devices, whether blood, urine or other test devices, are bulky and complex, so they can only be placed in fixed locations (such as large medical centers). For testing, it is necessary to go to a fixed location in person. It is quite inconvenient. Although medical institutions have introduced medical examinations for special vehicles, they can avoid waiting for a long time. However, they still have to go to a fixed location in person. If there is mobility, it is still necessary to enter and exit. Trouble with the portal, up and down stairs (or elevator).

Therefore, it is necessary to develop new technologies to solve the above shortcomings and problems.

The object of the present invention is to provide a portable biochemical detecting device which has a simple portable device, a spherical pivoting portion with multi-directional deflection detection, a spherical pivoting portion and a working rotating disc, and the like. efficacy. In particular, the problems to be solved by the present invention include: problems such as a portable detection structure having a simple structure.

The technical means for solving the above problems is to provide a portable biochemical detecting device, comprising: a sealed casing having an opening, a door, a top, a bottom, a plurality of side walls and a working space; the door has a first position and a second position, the door closes the opening when in the first position, the door opens the opening when in the second position; the top has a longitudinal slot; a side window is provided with a see-through window; a working rotary disc is disposed on the bottom for rotating and carrying at least one component to be detected; a spherical pivoting portion having a pair of chutes, an outer ball joint, and a An inner ball joint, an optical reading unit, a supporting portion and a beam splitter, the beam splitter having a first surface and a second surface; and wherein the spherical pivoting portion is permeable to the pair of chutes in the longitudinal direction Sliding on the groove, and the inner ball joint can be deflected in a multi-directional manner on the outer ball joint, thereby changing the position and angle of the beam splitter; a pair of telescopic partitions are disposed on the longitudinal groove and located in the spherical shape Both ends of the pivoting portion, the pair The contracting portion moves along the longitudinal groove with the spherical pivoting portion, and the airtight unit is kept closed by the expansion and contraction; an illuminating unit is disposed beside the see-through window for emitting a working beam, which is worn Passing through the see-through window to reflect a first light beam to the to-be-detected component through the first surface of the beam splitter, and then reflecting a second light beam from the to-be-detected component, which penetrates the first and second surfaces of the beam splitter Arriving at the optical reading unit; an optical analysis unit connecting the light emitting unit and the optical reading unit to read an optical signal of the working beam on the light emitting unit, and the optical reading unit The optical signal of the two beams is used to calculate the amount of light absorption of the element to be detected.

The above objects and advantages of the present invention will be readily understood from the following detailed description of the preferred embodiments illustrated herein.

The invention will be described in detail in the following examples in conjunction with the drawings:

Referring to the first, second, third and fourth figures, the present invention is a portable biochemical detecting device comprising: a sealed casing 10 having an opening 11, a door 12, a top 13, and a a bottom portion 14, a plurality of side walls 15 and a working space 16; the door 12 has a first position P1 and a second position P2. When the first position P1 is located, the door 12 closes the opening 11 when located In the second position P2, the door 12 opens the opening 11; the top portion 13 has a longitudinal slot 131; further, one of the side walls 15 is provided with a see-through window 151; a working wheel 21 is disposed on the bottom portion 14 For rotating and carrying at least one component to be detected 91; a spherical pivoting portion 30 having a pair of chutes 31, an outer ball joint 32, an inner ball joint 33, an optical reading unit 34, and a support Part 35 and a beam splitter 36. The beam splitter 36 has a first surface 361 and a second surface 362. Further, the spherical pivot portion 30 is slidable on the longitudinal slot 131 through the pair of sliding slots 31, and the inner ball joint 33 The outer ball joint 32 can be deflected in multiple directions, and the position and angle of the beam splitter 36 can be changed. A pair of telescopic partitions 40 are disposed on the longitudinal groove 131 and located at the spherical pivot portion 30. At both ends, the pair of telescopic partitions 40 move along the longitudinal groove 131 with the spherical pivoting portion 30, and the airtight casing 10 is kept closed (see first and fourteenth drawings); The unit 50 is disposed beside the see-through window 151 (as shown in the eighth and ninth figures) for emitting a working light beam L1 passing through the see-through window 151 and reflected by the first surface 361 of the beam splitter 36. a first light beam L2 to the element to be detected 91, and a second light beam L3 reflected from the element to be detected 91, which penetrates the first and second surfaces 361 and 362 of the beam splitter 36 to reach the optical reading The unit 34 is coupled to the light-emitting unit 50 and the optical reading unit 34 to read the light-emitting unit 50. The optical signal of the light beam L1, the optical reading of the signal of the second light beam L3 and the optical unit 34, to the light absorption amount calculated to be the detecting element 91.

In practice, the present invention further includes a working rotating portion 20, which is provided with the working rotary disk 21 and a rotary power source 22 (as shown in FIG. 7), the working rotary disk 21 has at least one receiving slot 211 for placing The element to be detected 91.

The plurality of slots 211 are arranged in a radial arrangement on the working disk 21, and each of the slots 211 is configured to be placed differently. The component 91 (including at least a first sample 91A, a second sample 91B, and a third sample 91C), and each of the pockets 211 has at least a first region A1 and a second region A2 connected to each other. And a third area A3 (as shown in the thirteenth B).

Further, the plurality of pockets 211 are dendritic structures distributed from the periphery of the working coil 21 toward the center of the circle (such as the second solid shown in the tenth and eleventh figures) For example, a plurality of different components to be detected 91 (including at least a first sample 91A, a second sample 91B, and a third sample 91C) can be placed in a cavity 211, and each container The slot 211 has at least a first area A1, a second area A2 and a third area A3 connected to each other.

The spherical pivoting portion 30 is slidable on the longitudinal groove 131 through the pair of sliding slots 31 (as shown in FIG. 5). If the spherical pivoting portion 30 has a virtual vertical axis A, the inner ball is The joint 33 is deflectable in multiple directions on the outer ball joint 32, thereby changing the position and angle of the beam splitter 36 (see the sixth figure).

In addition, in view of the fact that the component to be detected 91 may contain viruses or bacteria, the present invention may add a sterilization and sterilization device 70 (as shown in the second figure), which may be a plasma generating device, after the detection operation is completed. The sterilization and sterilizing device 70 can be activated, and the plasma is freely collided in the working space 16 by the plasma (the stencil pattern in the working space 16 of the second drawing is an exaggerated representation of the plasma), and the element to be detected 91 may be scattered. The virus and bacteria in the workspace 16 are eliminated, and the virus or bacteria which may be contained in the element to be detected 91 can be prevented from being scattered.

The actual use of the present invention is as follows: Referring to the twelfth A and twelfth B, the predetermined element to be detected 91 is placed in the pocket 211 of the working disk 21 (the reservoir 211 may be pre-placed with the test reagent) Initiating the rotary power source 22 to drive the working disc 21 to rotate (mixing the element to be detected 91 with the test reagent, if the rotation speed is slow, it may only flow to the third area A3, and if the rotation speed is fast, it may flow to the first area A1, The area control speed that can be detected according to actual needs is stopped after a predetermined time, and the illumination unit 50 is activated to illuminate the working surface L1 toward the first surface 361 of the beam splitter 36 via the see-through window 151; the working beam L1 is reflected by the first surface 361. a light beam L2 to the detecting element 91 in the receiving groove 211 on the working disk 21 (assumed to be the second area A2 of the tenth receiving groove) (assuming the first sample 91A, may be blood or urine to be detected) Alternatively, the second light beam L3 is reflected by the first sample 91A, and penetrates the first and second surfaces 361 and 362 and is irradiated to the optical reading unit 34.

Controlling the optical analysis unit 60 to read the optical signal of the working light beam L1 on the light emitting unit 50 through the light emitting unit 50 and the optical reading unit 34, respectively. And the optical signal of the second light beam L3 on the optical reading unit 34 to calculate the light absorption amount of the first sample 91A, assuming that the first sample 91A is blood, and the normal light absorption amount is 2 units, the amount of light of the working beam L1 is 5 units, and the amount of light lost by the first beam L1 reflected by the first surface 361 of the beam splitter 36 is not calculated (ignoring the value of the detection result), therefore, The amount of light of the second light beam L3 reflected by the first sample 91A of the light beam L1 should be 3 units. If the detection result is consistent, the first sample 91A is normal. If the light absorption amount of the first sample 91A is different, it represents The blood is not normal. This principle is the same as what the industry calls "enzyme immunoassay" (known principles, not to be repeated).

With the same detection principle, the spherical pivoting portion 30 is moved on the longitudinal groove 131 (for example, from the position of the twelfth A picture to the position of the thirteenth A picture), or the work wheel 21 is rotated. (As shown in the thirteenth and twenty-thirdth Cth drawings), the test object 91 to be tested can be performed on other pockets 211 on the work disk 21 (which can also detect different regions of the same cavity 211). Detection, the relevant structure is moved according to the actual situation.

Furthermore, referring to the fourteenth figure, the inner ball joint 33 can be directly deflected on the outer ball joint 32, and the position and angle of the beam splitter 36 can be changed. Of course, the light-emitting unit 50 needs to change the light-emitting angle according to the setting. This can also achieve the test results.

In summary, the advantages and effects of the present invention can be summarized as follows:

[1] Simple portable device. According to the present invention, only the working rotating portion and the spherical pivoting portion are provided in a sealed casing, and the portable light emitting unit and the optical analyzing portion are additionally provided, so that the inspection instrument can be moved to the place where it is needed at any time, and the mobility is relatively high.

[2] A spherical pivot portion having multi-directional deflection detection. The inner ball joint on the spherical pivot portion of the present invention can be deflected in a multi-directional manner on the outer ball joint, thereby interlocking the beam splitter so that the working beam can be reflected to the desired groove to be detected on the working wheel, that is, As long as the single inner ball joint is pushed, the beam splitter can be multi-directionally deflected for detection.

[3] Both the spherical pivoting portion and the working dial can be rotated. The invention is in a closed casing The longitudinal slot is provided for the spherical pivoting portion to move to a predetermined position on the working rotary disc, and the working rotary disc can also rotate, so that the predetermined measuring slot can be rotated under the beam splitter, so the movement mode is equivalent Diversified, all adjusted according to actual needs.

The present invention has been described in detail with reference to the preferred embodiments of the present invention, without departing from the spirit and scope of the invention.

From the above detailed description, those skilled in the art can understand that the present invention can achieve the foregoing objects, and has been in compliance with the provisions of the patent law, and has filed an application for an invention patent.

10‧‧‧Closed housing

11‧‧‧ openings

12‧‧‧

13‧‧‧ top

131‧‧‧Longitudinal slot

14‧‧‧ bottom

15‧‧‧ side wall

151‧‧ ‧ perspective window

16‧‧‧Work space

20‧‧‧Working Rotation Department

21‧‧‧Working wheel

211‧‧‧ 容容

22‧‧‧Rotating power source

30‧‧‧Spherical pivoting

31‧‧‧Chute

32‧‧‧Outer ball joint

33‧‧‧Inner ball joint

34‧‧‧Optical reading unit

35‧‧‧Support

36‧‧‧beam splitter

361‧‧‧ first surface

362‧‧‧ second surface

40‧‧‧Flexible isolation

50‧‧‧Lighting unit

60‧‧‧Optical Analysis Department

70‧‧ ‧ disinfection and sterilization device

91‧‧‧Components to be tested

91A‧‧‧First sample

92B‧‧‧Second specimen

93C‧‧‧ third specimen

P1‧‧‧ first position

P2‧‧‧ second position

L1‧‧‧Working beam

L2‧‧‧First beam

L3‧‧‧second beam

A1‧‧‧ first area

A2‧‧‧Second area

A3‧‧‧ third area

A‧‧‧ virtual vertical axis

The first figure is a schematic view of the present invention

The second picture is a cross-sectional view of the first figure

The third figure is an exploded schematic view of the partial structure of the present invention.

The fourth figure is a schematic diagram of the combination of the third figure.

Figure 5 is a partial enlarged view of the spherical pivot portion of the present invention on the longitudinal groove

Figure 6 is a schematic view showing the multidirectional deflection of the inner ball joint of the present invention on the outer ball joint

Figure 7 is a partial enlarged view of the working rotating portion of the present invention

Figure 8 is a partial enlarged view of the light-emitting unit of the present invention

Figure 9 is a schematic view of a first embodiment of the housing of the present invention

Figure 10 is a schematic view showing a second embodiment of the housing of the present invention

The eleventh figure is a partial enlarged view of the tenth figure

Twelfth A and Twelfth B are schematic views of the first detection mode of the present invention

The thirteenth, thirteenth and thirteenthth Cth drawings are schematic diagrams of the second detection mode of the present invention

Figure 14 is a schematic view of the third detection mode of the present invention

10. . . Closed housing

11. . . Opening

12. . . door

13. . . top

131. . . Vertical slot

14. . . bottom

15. . . Side wall

151. . . Perspective window

16. . . Workspace

20. . . Working rotation

twenty one. . . Work coil

211. . . Crate

twenty two. . . Rotary power source

30. . . Spherical pivot

32. . . Outer ball joint

35. . . Support

36. . . Beam splitter

40. . . Telescopic isolation

50. . . Light unit

60. . . Optical analysis department

P1. . . First position

P2. . . Second position

L1. . . Working beam

L2. . . First beam

L3. . . Second beam

Claims (7)

A portable biochemical detecting device comprises: a sealed casing having an opening, a door, a top, a bottom, a plurality of side walls and a working space; the door has a first position and a second a position, the door closes the opening when in the first position, the door opens the opening when in the second position; the top has a longitudinal groove; and one of the side walls is provided with a see-through window; a working rotary disc is disposed on the bottom for rotating and carrying at least one component to be detected; a spherical pivoting portion having a pair of chutes, an outer ball joint, an inner ball joint, and an optical reading a unit, a supporting portion and a beam splitter, the beam splitter has a first surface and a second surface; further, the spherical pivoting portion is slidable on the longitudinal slot through the pair of sliding slots, and the inner ball The joint can be deflected in a multi-directional manner on the outer ball joint, thereby changing the position and angle of the beam splitter; a pair of telescopic partitions are disposed on the longitudinal groove and located at two ends of the spherical pivot portion, The telescopic isolation portion is associated with the spherical pivot portion Moving in a longitudinal slot, and following the expansion and contraction to keep the sealed casing closed; an illumination unit is disposed beside the see-through window for emitting a working beam that passes through the see-through window and passes through the first surface of the beam splitter Reflecting a first light beam to the element to be detected, and reflecting a second light beam from the element to be detected, which penetrates the first and second surfaces of the beam splitter to reach the optical reading unit; an optical analysis unit, Connecting the light emitting unit and the optical reading unit, and reading an optical signal of the working beam on the light emitting unit and an optical signal of the second light beam on the optical reading unit to calculate the to-be-detected component The amount of light absorbed. The portable biochemical detecting device according to claim 1, further comprising: a working rotating portion, the working rotating disc and a rotating power source, wherein the working rotating disc has at least one receiving groove for Place the component to be tested. A portable biochemical detection device as described in claim 1 of the patent application, The working disk has a plurality of radially arranged slots, and each of the slots is configured to place the component to be detected. The portable biochemical detection device of claim 1, wherein: the working disk has a plurality of radially arranged cavities, wherein each of the cuvettes is used for placing the component to be detected; Each of the pockets has at least a first region, a second region and a third region connected to each other. The portable biochemical detecting device according to claim 1, wherein the working disc has a plurality of radially arranged cavities; each of the cavities is distributed from the periphery of the working disc toward the center of the circle. The dendritic structure is used to place a plurality of components to be detected. The portable biochemical detecting device according to claim 1, wherein the working disc has a plurality of radially arranged cavities; each of the cavities is distributed from the periphery of the working disc toward the center of the circle. a dendritic structure for arranging a plurality of components to be detected, and having at least a first region, a second region and a third region connected thereto. The portable biochemical detecting device according to claim 1, further comprising: a disinfecting and sterilizing device disposed in the working space for containing viruses and bacteria in the working space to be detected Eliminate exhaustion.