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TW200720239A - Styrylsulfonamides, their manufacture and use as pharmaceutical agents - Google Patents

Styrylsulfonamides, their manufacture and use as pharmaceutical agents

Info

Publication number
TW200720239A
TW200720239A TW095117488A TW95117488A TW200720239A TW 200720239 A TW200720239 A TW 200720239A TW 095117488 A TW095117488 A TW 095117488A TW 95117488 A TW95117488 A TW 95117488A TW 200720239 A TW200720239 A TW 200720239A
Authority
TW
Taiwan
Prior art keywords
manufacture
styrylsulfonamides
pharmaceutical agents
compounds
above compounds
Prior art date
Application number
TW095117488A
Other languages
English (en)
Inventor
Edward Boyd
Frederick Brookfield
Jonathan Gridley
Matthias Koerner
Manfred Kubbies
Raymond Lau
Ulrike Reiff
Georg Tiefenthaler
Der Saal Wolfgang Von
Timothy Woodcock
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of TW200720239A publication Critical patent/TW200720239A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C07C311/46—Y being a hydrogen or a carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/51—Y being a hydrogen or a carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW095117488A 2005-05-20 2006-05-17 Styrylsulfonamides, their manufacture and use as pharmaceutical agents TW200720239A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05010982 2005-05-20
EP06001007 2006-01-18

Publications (1)

Publication Number Publication Date
TW200720239A true TW200720239A (en) 2007-06-01

Family

ID=36607423

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095117488A TW200720239A (en) 2005-05-20 2006-05-17 Styrylsulfonamides, their manufacture and use as pharmaceutical agents

Country Status (13)

Country Link
US (1) US7208526B2 (zh)
EP (1) EP1888519A2 (zh)
JP (1) JP2008545633A (zh)
KR (1) KR100929996B1 (zh)
CN (1) CN101268042A (zh)
AR (1) AR057300A1 (zh)
AU (1) AU2006312801A1 (zh)
BR (1) BRPI0611287A2 (zh)
CA (1) CA2607982A1 (zh)
IL (1) IL186851A0 (zh)
MX (1) MX2007014224A (zh)
TW (1) TW200720239A (zh)
WO (1) WO2007054139A2 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010526844A (ja) * 2007-05-16 2010-08-05 エフ．ホフマン−ラ ロシュ アーゲー アリールピリジルスルホンアミド誘導体、それらの製造法及び医薬剤としての使用
EP2701701B1 (en) 2011-04-28 2018-01-24 Celgene Corporation Methods and compositions using pde4 inhibitors for the treatment and management of autoimmune and inflammatory diseases
AR090100A1 (es) 2012-02-21 2014-10-22 Celgene Corp Procesos para la preparacion de la (s)-1-(3-etoxi-4-metoxifenil)-2-metanosulfoniletilamina
NZ628329A (en) 2013-06-17 2017-12-22 Celgene Corp Formulations of (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206142A (en) * 1973-06-11 1980-06-03 Mead Johnson & Company Styrylamidine process
US3983107A (en) * 1973-12-05 1976-09-28 Pfizer Inc. Hypolipidemic alkenesulfonamides
CA1071651A (en) * 1974-04-08 1980-02-12 William L. Matier Styrylamidines
US4157257A (en) * 1976-10-01 1979-06-05 Utsunomiya University Benzenesulfonamide derivatives
JPS5936663A (ja) * 1983-05-27 1984-02-28 Ishihara Sangyo Kaisha Ltd ベンズアミド誘導体及びそれらを含有する除草剤
US5591761A (en) 1993-05-20 1997-01-07 Texas Biotechnology Corporation Thiophenyl-, furyl-and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
WO1998015530A1 (en) * 1996-10-08 1998-04-16 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives
PT964849E (pt) * 1997-01-29 2003-08-29 Pfizer Derivados de sulfonilureia e sua utilizacao no controlo da actovidade da interleucina-1
CN1268942A (zh) * 1997-06-27 2000-10-04 藤泽药品工业株式会社 磺酰胺化合物及其药物用途
DE19742951A1 (de) * 1997-09-29 1999-04-15 Hoechst Schering Agrevo Gmbh Acylsulfamoylbenzoesäureamide, diese enthaltende nutzpflanzenschützende Mittel und Verfahren zu ihrer Herstellung
US6410584B1 (en) * 1998-01-14 2002-06-25 Cell Pathways, Inc. Method for inhibiting neoplastic cells with indole derivatives
UA74889C2 (en) 2001-06-06 2006-02-15 Lilly Co Eli Benzoylsulfonamides and sulfonylbenzamidines for the application as antitumour agents
AU2002323098A1 (en) * 2001-08-11 2003-03-03 Bristol-Myers Squibb Pharma Company Selective estrogen receptor modulators
AR037097A1 (es) * 2001-10-05 2004-10-20 Novartis Ag Compuestos acilsulfonamidas, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento
ATE375978T1 (de) 2002-11-22 2007-11-15 Lilly Co Eli Benzoylsulfonamide als antitumor-mittel

Also Published As

Publication number Publication date
CA2607982A1 (en) 2007-05-18
MX2007014224A (es) 2008-02-07
IL186851A0 (en) 2008-02-09
BRPI0611287A2 (pt) 2010-08-31
US20060270874A1 (en) 2006-11-30
AR057300A1 (es) 2007-11-28
EP1888519A2 (en) 2008-02-20
WO2007054139A3 (en) 2008-05-29
KR100929996B1 (ko) 2009-12-07
AU2006312801A1 (en) 2007-05-18
CN101268042A (zh) 2008-09-17
US7208526B2 (en) 2007-04-24
WO2007054139A2 (en) 2007-05-18
KR20070120195A (ko) 2007-12-21
JP2008545633A (ja) 2008-12-18

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